scholarly journals Inflammatory Odontogenic Cysts

2021 ◽  
Vol 17 (3) ◽  
pp. 135-144
Author(s):  
Marwa Abdul-Salam Hamied ◽  
Salwa M. Al-Shaikhani ◽  
Zana D. Ali

 Cystic conditions of the jaw cause bony destruction and may cause resorption or displacement of adjacent teeth. Odontogenic cysts have developmental or inflammatory origins. To describe in detail the inflammatory odontogenic cysts, a manual search was done in hard copy books of oral and maxillofacial pathology, and an electronic search was done in the google website, oral and maxillofacial pathology E-books, PubMed, Research Gate, Academia, and Google scholar using the keywords "odontogenic cysts," "classification of the odontogenic cysts," "radicular cyst," "periapical cyst," "lateral inflammatory cyst," "residual cyst," "paradental cyst," "collateral inflammatory cyst," "treatment of inflammatory odontogenic cysts," and matching each odontogenic inflammatory cyst subtype with these words "gross description," "pathogenesis," "microscopical,"  clinical," "radiographical" appearance. Articles published till February 2021 were included in this review.  In conclusion, an accurate diagnosis of an inflammatory odontogenic cyst requires information relative to its clinical, radiographical, macro- and microscopical findings. In many instances, two cysts that are classified differently may exhibit similar histopathological features. In such cases, clinical and radiographic findings are necessary to make a precise diagnosis.

Author(s):  
Dagar Mona ◽  
Sharma Anamika

The diagnosis "Aggressive Periodontitis", defined by the International Workshop for Classification of Periodontal Diseases and Conditions in 1999, refers to the multifactorial, severe, and rapidly progressive form of Periodontitis, which primarily – but not exclusively – affects younger patients. Aggressive periodontitis have localized and generalized forms. It is currently believed that combination of bacteriologic, immunologic and hereditary factors are of major importance in the etiology of this disease. The case was of a 20 year old female and her clinical and radiographic findings were typical for generalized Aggressive Periodontitis. Treatment consisted of thorough scaling and root planing along with administration of tetracycline250 mg every six hours for three weeks, followed by surgical intervention. Keywords: Aggressive periodontitis, multifactorial disease, treatment


2021 ◽  
Vol 17 (2) ◽  
pp. 52-61
Author(s):  
Marwa A. Hamied ◽  
Salwa M. Al-Shaikhani ◽  
Zana D. Ali

Purpose: to review in detail various aspects of odontogenic keratocyst, emphasizing recent nomenclature, clinical, histopathological, recurrence, and management of odontogenic keratocyst. Methods: To achieve the objective of this review, a manual search was done in hard copy books of oral and maxillofacial pathology, and an electronic search was done in the google website, oral and maxillofacial pathology E-books, virtual database sites, such as PubMed, Research Gate, Academia, and Google scholar using the descriptors: odontogenic cyst, kerato odontogenic tumor, odontogenic keratocyst, and jaws cystic lesion. The eligibility criteria for selecting articles were: to be in the English language, studies published in journals, or indexed in these databases until 2021. Exclusion criteria were: articles in any languages other than English, studies presented in duplicate between the bases, whose theme did not contemplate the objective proposed in this review, or those not available in the digital environment. Data collection occurred from October to December 2020, followed by a thorough evaluation of the studies found, including an exploratory, selective, analytical, and interpretative reading. Summary and conclusions: the odontogenic keratocyst is noteworthy because of its unusual growth pattern, the tendency to recur, and association with an inherited syndrome. The renaming of odontogenic keratocysts as keratocystic odontogenic tumors has been one of the most debatable changes in the terminology of odontogenic lesions in recent years. Early diagnose of this lesion is important to perform the more conservative treatment. A wait-and-see policy, with yearly follow-up for the first five years and every two years after that, is strongly advocated.


Author(s):  
Mashhour Bani Amer ◽  
Mohammad Amawi ◽  
Hasan El-Khatib

In this paper, a neural fuzzy system for the diagnosis of potassium disturbances is presented. This paper develops an adaptive neuro-fuzzy expert system that can provide accurate diagnosis of potassium disturbances. The proposed diagnostic approach has many attractive features. First, it provides an efficient tool for diagnosis of K+ disturbances and aids clinicians, especially the non-expert ones, in providing fast and accurate diagnosis of K+ disturbances in critical time. Second, it significantly reduces the time needed to accomplish precise diagnosis of K+ disturbances and thus enhances the healthcare standards. Third, it is capable of diagnosing the different types of potassium disturbances using a hybrid neural fuzzy approach. Finally, it has good accuracy (higher than 87%), specificity (100%), and average sensitivity (83%). The performance of the proposed diagnostic system was experimentally evaluated and the achieved results confirmed that the proposed system is efficient and accurate in diagnosing K+ disturbances.


Author(s):  
Keith L. Ligon ◽  
Karima Mokhtari ◽  
Thomas W. Smith

This chapter presents the most up-to-date classification of tumors of the nervous system, based on the histological appearance of the neoplasm and also on information derived from cytogenetics and molecular biology, now recognized worldwide as increasingly important for more precise diagnosis, prognosis, and therapeutic guidance. The chapter provides a detailed morphologic description of each major tumor type, with numerous illustrations of macroscopic and microscopic lesions. First we consider primary tumors of the nervous system, including those derived from neuroepithelial tissue (astrocytic, oligodendroglial, ependymal, neuronal, and glioneuronal), pineal tissue, peripheral nerve sheath, and meninges. Next lymphomas, hematopoietic neoplasms, and secondary (metastatic) neoplasms are described.


2018 ◽  
Vol 6 (3) ◽  
pp. e000592 ◽  
Author(s):  
Naomi F Earley ◽  
Michael E Herrtage ◽  
Jon L Hall

Congenital lobar emphysema is a rare condition in dogs. A three-month-old pug presented with acute dyspnoea and radiographic findings diagnosed congenital lobar emphysema. Due to the patient’s rapidly deteriorating ventilation, an emergency right middle lung lobectomy was performed and recovery was uneventful. This case report describes the importance of making a prompt and accurate diagnosis of this condition, based on radiographic findings, to facilitate immediate treatment.


2019 ◽  
Vol 11 (11) ◽  
pp. e10-e10
Author(s):  
Nicolas K Khattar ◽  
Andrew C White ◽  
Shawn W Adams ◽  
Zaid S Aljuboori ◽  
Michael J Wilder ◽  
...  

Intracranial vascular pathologies often have overlapping clinical presentations. Dissected vessel occlusions and bifurcation aneurysms can appear similar on pretherapeutic imaging. The medical management of these two entities is drastically different. The patient is a 51-year-old man who presented with severe, sudden-onset headache. Initial presentation was consistent with a ruptured middle cerebral artery (MCA) aneurysm and surgical clipping was recommended. However, further review of radiographic findings could not definitively differentiate an aneurysmal origin of the symptoms as opposed to intracranial dissection followed by occlusion of the M2 branch of the MCA. MRI sampling perfection with application optimised contrasts using different flip angle evolution (SPACE) was performed and showed thin flow signalling distal to the dissected vessel stump confirming the diagnosis. Accurate diagnosis is a crucial step in directing treatment for intracranial vascular lesions. MRI SPACE is a simple tool in the diagnostic armamentarium to adequately direct treatment and avoid the potential for unnecessary interventions.


2019 ◽  
Vol 6 (3) ◽  
pp. e560 ◽  
Author(s):  
Leslie A. Benson ◽  
Hojun Li ◽  
Lauren A. Henderson ◽  
Isaac H. Solomon ◽  
Ariane Soldatos ◽  
...  

ObjectiveTo highlight a novel, treatable syndrome, we report 4 patients with CNS-isolated inflammation associated with familial hemophagocytic lymphohistiocytosis (FHL) gene mutations (CNS-FHL).MethodsRetrospective chart review.ResultsPatients with CNS-FHL are characterized by chronic inflammation restricted to the CNS that is not attributable to any previously described neuroinflammatory etiology and have germline mutations in known FHL-associated genes with no signs of systemic inflammation. Hematopoietic stem cell transplantation (HCT) can be well tolerated and effective in achieving or maintaining disease remission in patients with CNS-FHL.ConclusionsEarly and accurate diagnosis followed by treatment with HCT can reduce morbidity and mortality in CNS-FHL, a novel, treatable syndrome.Classification of evidenceThis study provides Class IV evidence that HCT is well tolerated and effective in treating CNS-FHL.


Author(s):  
Nádya Santos Moura ◽  
Maria Luziene Sousa Gomes ◽  
Ivana Rios Rodrigues ◽  
Daniel Lorber Rolnik ◽  
Fabrício Silva Costa ◽  
...  

Abstract Objective To identify the most effective procedures recommended for the prevention of preeclampsia. Data Sources A systematic review was performed in the following databases: Pubmed/MEDLINE, CINAHL, Web of Science, Cochrane and LILACS via the Virtual Health Library (VHL). A manual search was also performed to find additional references. The risk of bias, the quality of the evidence, and the classification of the strength of the recommendations were evaluated using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach. Selection of Studies In the initial search in the databases, the total number of articles retrieved was 351, and 2 were retrieved through the manual search; after duplicate articles were removed, 333 citations remained. After a thorough review of the titles and abstracts, 315 references were excluded. Accordingly, 18 articles were maintained for selection of the complete text (phase 2). This process led to the exclusion of 6 studies. In total, 12 articles were selected for data extraction and qualitative synthesis. Data Collection The articles selected for the study were analyzed, and we inserted the synthesis of the evidence in the online software GRADEpro Guideline Development Tool (GDT) (McMaster University and Evidence Prime Inc. All right reserved. McMaster University, Hamilton, Ontário, Canada); thus, it was possible to develop a table of evidence, with the quality of the evidence and the classification of the strength of the recommendations. Data Synthesis In total, seven studies recommended the individual use of aspirin, or aspirin combined with calcium, heparin or dipyridamole. The use of calcium alone or in combination with phytonutrients was also highlighted. All of the studies were with women at a high risk of developing preeclampsia. Conclusion According to the studies evaluated, the administration of aspirin is still the best procedure to be used in the clinical practice to prevent preeclampsia.


Blood ◽  
1989 ◽  
Vol 73 (7) ◽  
pp. 1987-1992 ◽  
Author(s):  
GL Kropp ◽  
S Fucharoen ◽  
SH Embury

Abstract Hemoglobin Constant Spring is an elongation mutation of the alpha 2- globin locus that results in a thalassemic phenotype. It has a high prevalence in Asian populations. When inherited with other alpha- thalassemia determinants, the Constant Spring gene has the potential to cause severe forms of alpha-thalassemia. Accurate diagnosis of the condition with standard hemoglobin electrophoresis is unreliable due to the small to undetectable amounts of the mutant hemoglobin present. Because of the extensive sequence homology of the alpha 1 and alpha 2 loci, allele-specific hybridization to total genomic DNA containing the Constant Spring gene would not distinguish between heterozygous and homozygous hemoglobin Constant Spring. Selective enzymatic amplification of alpha 2-globin DNA sequences, however, allows unambiguous diagnoses to be made using allele-specific hybridization. This method is useful for providing accurate genetic counseling and prenatal diagnosis in populations and specific families in which precise diagnosis is important.


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