scholarly journals The Impact of COVID-19 on Healthy Related Issues, A structured Review

2021 ◽  
Vol 17 (3) ◽  
pp. 152-157
Author(s):  
Hiyam Rauof Al-Hamamy

Coronavirus: (COVID-19) is a recently discovered viral disease caused by a new strain of coronavirus. The majority of patients with corona-virus infections will have a mild-moderate respiratory disease that recovers without special care. Most often, the elderly, and others with chronic medical conditions such as asthma, coronary disease, respiratory illness, and malignancy are seriously ill.     COVID-19 is spread mostly by salivary droplets or nasal secretions when an infected person coughs or sneezes.     COVID-19 causes severe acute respiratory illness (SARS-COV-2). The first incidence was recorded in Wuhan, China, in 2019.  Since then it spreads leading to a pandemic. The typical incubation time for COVID-19 infection is 2-14 days (normally 5). The common features include fever, cough, tiredness, difficulty in breathing, loss of smell or taste. Occasionally, signs are absent. COVID-19 complications include renal failure, syndrome of cytokine release, pneumonia, respiratory failure, lung fibrosis.

2021 ◽  
Vol 19 ◽  
Author(s):  
Mohamed Said Boulkrane ◽  
Victoria Ilina ◽  
Roman Melchakov ◽  
Mikhail Arisov ◽  
Julia Fedotova ◽  
...  

: The World Health Organization declared the pandemic situation caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2) in March 2020, but the detailed pathophysiological mechanisms of Coronavirus disease 2019 (COVID-19) are not yet completely understood. Therefore, to date, few therapeutic options are available for patients with mild-moderate or serious disease. In addition to systemic and respiratory symptoms, several reports have documented various neurological symptoms and impairments of mental health. The current review aims to provide the available evidence about the effects of SARS-CoV-2 infection on mental health. The present data suggest that SARS-CoV-2 produces a wide range of impairments and disorders of the brain. However, a limited number of studies investigated the neuroinvasive potential of SARS-CoV-2. Although the main features and outcomes of COVID-19 are linked to severe acute respiratory illness. The possible damages on the brain should be considered, too.


2020 ◽  
Vol 10 (4) ◽  
pp. 312-315
Author(s):  
Olga Berdina ◽  
Irina Madaeva ◽  
Liubov Rychkova

In the literature, there are suggestions of a possible mutual influence between obstructive sleep apnea (OSA) and the novel coronavirus disease 2019 (COVID-19). The aim of this review is to analyze data found in the literature related to pathogenetic aspects of the impact of OSA on COVID-19, and vice versa, and features of the course of this comorbidity in both adulthood and childhood. Information was searched in MEDLINE, PubMed, EBSCO, and RSCI databases, which presented some data for the connection between COVID-19 and OSA, as well as aspects of OSA and COVID-19 comorbidity for adults and the elderly. The common pathophysiological pathways leading to increased systemic inflammation and adverse consequences of OSA and COVID-19 infection do coexist and were revealed in detail. We paid special attention to aspects of this comorbidity in children and found that research in this area was lacking. Based on this information, it should be concluded that: 1) more pediatric studies of links between OSA and COVID-19 are urgently needed; 2) screening hospitalized COVID-19 patients with tools to detect OSA could identify those at risk for a severe course of these diseases and adverse outcomes; 3) treating OSA will allow increasing the likelihood of developing a robust and long-lasting post-COVID-19 adaptive immunity in these patients.


2020 ◽  
pp. 1-4
Author(s):  
Punit Gupta ◽  
◽  
Sulakshna D ◽  

COVID-19, a respiratory illness caused by a newly discovered coronavirus, has become a pandemic affecting over 1.9 million people with over 130,000 deaths in 210 countries.Some people become infected with the virus but do not develop symptoms. When they appear, symptoms are non-specific, with fever, cough, shortness of breath, sore throat, fatigue, and headache being the most common. Symptoms are usually mild and benign in a vast majority (>80%) and recede gradually, leading to a full spontaneous recovery. A small number become seriously ill, develop difficulty in breathing and complications related to other organs. They may require hospitalization and a smaller subset need ICU care. The mortality is relatively higher in the latter group. This risk goes up in the elderly and those with co-orbidities (such ashypertension, diabetes, cardiac disease, kidney failure). Still, it is essential to emphasize that everybody is at risk for severe disease (including the relatively young and healthy dialysis staff). The strategy of physical distancing, case finding, contact tracing and quarantine/isolation of positive cases and high-risk contacts is critical to controlling the spread of this infection. This strategy is being implemented through nationwide lockdown during the period of intense transmission. Still, physical distancing is likely to remain in force after the end of the current lockdown to prevent disease spread.


2020 ◽  
Vol 375 (1811) ◽  
pp. 20190607 ◽  
Author(s):  
Melissa Emery Thompson ◽  
Zarin P. Machanda ◽  
Stephanie A. Fox ◽  
Kris H. Sabbi ◽  
Emily Otali ◽  
...  

While declining physical performance is an expected consequence of ageing, human clinical research has placed increasing emphasis on physical frailty as a predictor of death and disability in the elderly. We examined non-invasive measures approximating frailty in a richly sampled longitudinal dataset on wild chimpanzees. Using urinary creatinine to assess lean body mass, we found moderate but significant declines in physical condition with age in both sexes. While older chimpanzees spent less of their day in the trees and feeding, they did not alter activity budgets with respect to travel or resting. There was little evidence that declining lean body mass had negative consequences independent of age. Old chimpanzees with poor lean body mass rested more often but did not otherwise differ in activity. Males, but not females, in poor condition were more likely to exhibit respiratory illness. Poor muscle mass was associated acutely with death in males, but it did not predict future mortality in either sex. While there may be some reasons to suspect biological differences in the susceptibility to frailty in chimpanzees versus humans, our data are consistent with recent reports from humans that lean, physically active individuals can successfully combat frailty. This article is part of the theme issue ‘Evolution of the primate ageing process’.


2020 ◽  
Vol 6 (02) ◽  
pp. 47-52
Author(s):  
Sapna Marcus ◽  
Rohit Mahajan

AbstractA pandemic coronavirus, termed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causes a respiratory illness called coronavirus disease 2019 (COVID-19) that is often severe or life threatening. Considering the low immunity status of cancer patients due to multimodality treatment, they seem to be more prone to COVID-19. Given the rapidity with which the novel coronavirus (SARS-CoV-2) is spreading, we can expect an increased burden of cancer patients diagnosed with COVID-19 at oncology treatment clinics and a need to address the issues associated. As of the date of this writing, United States has been witnessing an increase in confirmed cases, not far behind are the large outbreaks of European countries. Patients with cancer may have compromised immunity due to their disease or its ongoing treatment, and early reports suggest cancer is a risk factor for severe COVID-19. Since the outbreak in Wuhan, Chinese researchers have published on their experience with COVID-19 and have highlighted high-risk groups, including the elderly and patients with comorbidities, including cancer. In one of the largest series reported from Wuhan, elderly patients were at a higher risk for disease severity with an 8.0% case fatality rate in those aged between 70 and 79 years, and 14.8% in those aged 80 years and older. The case fatality rate for cancer patients in that cohort was notably higher than noncancer patients at 5.6 versus 2.1% in the whole sample. This review focuses on the pandemic-driven strategies that need to be adopted to overcome the radiation oncology clinics burden, especially in this region of India popularly termed as the cancer belt. Although colleagues around the world have dealt with enormous service pressures in the face of natural disaster or infection previously, the global scale and challenge of COVID-19 are unprecedented. Our aim is to highlight the quintessential point that even within these circumstances the morbidity and mortality associated with cancer should not be taken lightly. Departmental protocols should be regularly upgraded to provide smooth and efficient functioning of the department.


Author(s):  
Nguyen Tan Danh

The proportion of the elderly in Vietnam is happening with rapidly growing numbers. This is an inevitable trend in Vietnamese society, and also a problem - a challenge for the government. The main goal of our country in particular is to point out and face the immediate situation (high aging rate of the population), and at the same time find a strategy that is suitable for the development of the country as well as consistent with the common interests of the current elderly group; making predictions to take the right steps to minimize the risks and risks from its negative sides. This article discusses the general situation of population aging in recent years in Vietnam; give specific numbers and statistics on this issue. From there, this article will highlight the opportunities and challenges that this country is facing - especially the impact on the country's economy and give a number of recommendations related to the improvementin order to build a satisfactory welfare and welfare system for the elderly in the current aging population in Vietnam. The article uses the method of surveying a number of interviewers to find suitable solutions, and the results show that the problem of the elderly, even though not alarmed since the elderly in Vietnam are still taken care by children and their families rather well. However, there is quite a big concern we need to pay more attention, that is, the economic burden will be an issue for society in the future, especially in the medical field.


2021 ◽  
Vol 12 ◽  
Author(s):  
Muhammad Harris Shoaib ◽  
Farrukh Rafiq Ahmed ◽  
Muhammad Sikandar ◽  
Rabia Ismail Yousuf ◽  
Muhammad Talha Saleem

The 2019 novel coronavirus (2019-nCoV), commonly known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) or coronavirus disease 2019 (COVID-19), was first revealed in late 2019 in Wuhan city, Hubei province, China. It was subsequently spread globally and thereby declared as a pandemic by WHO in March 2020. The disease causes severe acute respiratory illness and is highly contagious due to the fast-onward transmission. As of the mid of November 2020, the disease has affected 220 countries with more than 16 million active cases and 1.3 million deaths worldwide. Males, pregnant women, the elderly, immunosuppressed patients, and those with underlying medical conditions are more vulnerable to the disease than the general healthy population. Unfortunately, no definite treatment is available. Although remdesivir as an antiviral had been approved for use in those above 12 years of age and 40 kg weight group, it has been observed to be ineffective in large-scale SOLIDARITY trials by WHO. Moreover, dexamethasone has been found to increase the recovery rate of ventilated patients; oxygen and inhaled nitric oxide as a vasodilator have been given emergency expanded access. In addition, more than 57 clinical trials are being conducted for the development of the vaccines on various platforms. Two vaccines were found to be significantly promising in phase III results. It is concluded that till the approval of a specific treatment or development of a vaccine against this deadly disease, the preventive measures should be followed strictly to reduce the spread of the disease.


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