scholarly journals The Prevalence of Pulmonary Aspergillosis Among Clinically Suspected and Undertreated Tuberculosis Patients in Khartoum State, Sudan

2021 ◽  
Vol 17 (3) ◽  
pp. 180-184
Author(s):  
Abubaker Agbash Baraka ◽  
Salma Ali Alabid ◽  
Mohammed Abdulgadir Mohammed ◽  
Nagla Mohammed Ahmed

Background Respiratory tract aspergillosis is a pulmonary disease cause by aspergillus species which are opportunistic fungi that mainly infect immuno-compromised patients .  Objective(s) The present study aimed to detect the frequency of pulmonary aspergillosis among clinically suspected and under follow up tuberculosis patients conducted at Tropical Diseases Teaching Hospital, Omdurman, Khartoum State , Sudan during the period from December 2019 to November 2020.  Materials and Methods One hundred and fifty sputum samples were collected from suspected cases of pulmonary tuberculosis and under follow up tuberculosis patients. All specimens were examined using 20% KOH and cultured on two sets of Sabouraudʹs Dextrose agar slope media with chloramphenicol. Results Asperigillus species were isolated from 9/150 (6%) patients. They represented 5(3.3%) A.fumigatus, 3 (2%) A. niger and 1 (0.6%) A. Flavus. It was found that all Aspergillus isolates were revealed from Non acid fast bacilli (Non AFB) patients 9/137(6.6%) with the most common frequency among asymptomatic patients 3/35(8.6%) , patients who were under tuberculosis treatment (8.5%), those who were under Rifampicin (RIF) and Isonizide (INH) treatment (10%) and with duration of less than three month. Also the higher percentage (13%) was represented among the age group range from 61-80 year and slightly among males 6/97 (6.2 %) than females 3/53 (5.7%). There was statistically non-significant association between the frequency of aspergillosis and the studied variables in this study. Conclusion  The frequency of pulmonary aspergillosis among patients with anti-tuberculosis treatment reflects the need for routine screening and diagnosis of those patients since the use of anti- tuberculosis treatment can promote the growth and reproduction of fungi. Keywords Pulmonary aspergillosis, tuberculosis, follow up patients. 

2021 ◽  
Vol 15 (7) ◽  
pp. 1794-1797
Author(s):  
Khalil Ahmed Memon ◽  
M. Khan ◽  
Sarah Azhar ◽  
Jai Kershan ◽  
Partab Puri ◽  
...  

Objective: To assess the prevalence rate of Hepatitis B and C among those patients who had tuberculosis in local community of Sindh, Pakistan. Study Design:Survey-based study Place and Duration of Study: Department of Pathology, Liaquat University of Medical & health Sciences Jamshoro from 1stJanuary 2020 to 31stDecember 2020. Methodology: Five hundred and eighty nine confirmed cases of tuberculosis patients were enrolled. The patients were further analyzed to assess either HBV, HCV or both are present or absent. Results: Three hundred and forty one (57.8%) were males and 248 (42.1%) were females. The majority of participants were in the age group of 45-54 years 147 (24.9%).The residence detail showed that 167 (28.3%) belonged to urban areas. Further 143 (24.2%) had sickness history of 2-6 months, 239 (40.5%) had history of 6-12 months, The prevalence of hepatitis B and C among tuberculosis patients showed, 17.8% (n=105) with Hepatitis B, 26.3% (n=155) were diagnosed with hepatitis C, 15.7% (n=93) had Both Hepatitis B and C, however 236 (40.0%) had no history with hepatitis. Hepatitis C was most frequently found age of above 54 years, 55 (9.3%). Conclusion:The control of tuberculosis has remained one of the greatest goals globally till date, the higher risk of liver complications, along with the Hepatitis B and Hepatitis C. Although the complications of Tuberculosis patients remain unsolved yet the possible efforts can be made to identify the earlier problems for the clinical prospective and a complete follow up of the records can optimize the management of Tuberculosis in co-existing conditions of hepatitis B and C. Key Words: Hepatitis B, Hepatitis C, Tuberculosis, Liver diseases


2015 ◽  
Vol 16 (1) ◽  
pp. 10-13 ◽  
Author(s):  
Munawar Hussain Soomro ◽  
Faisal Shahzad ◽  
Muhammad Amir Khan ◽  
Ejaz Qadeer ◽  
Odd Mørkve

Background: Tuberculosis is a serious global public health, social and economical problem that affects millions of people particularly in low income countries. The aim of this study was to see the loss to follow up pattern in Tuberculosis patients in district Rawalpindi, Pakistan. Materials and method: A cross-sectional study was conducted in district Rawalpindi between August and October 2010. All sputum smear positive Tuberculosis patients diagnosed and treated in public sector, urban and rural diagnostic centers of the district Rawalpindi during the year 2008 were included in the study.All cases other (smear negative pulmonary and extra-pulmonary) than sputum smear positive and all private hospitals were excluded. Results: A total of 451 patients were enrolled in the study. Majority of the patients (89.6%) were provided with the treatment support. Geographically dropout rate was observed higher in urban patients than in rural 18.7% vs. 10.5%. On the other hand by patient gender, drop out was seen more in male patients than in females 16.5% vs. 13.1%. By patients age groups, interestingly patients under the childhood age group all the patients completed the treatment while drop out was observed more in older age group. Conclusions: Loss to follow up pattern was seen more in urban patients, by gender more in male patients and by age groups observed more in older patients.DOI: http://dx.doi.org/10.3329/jom.v16i1.22374 J MEDICINE 2015; 16 : 10-13


2021 ◽  
Vol 13 (1) ◽  
pp. 11-17
Author(s):  
Mamadou Saliou Sow ◽  
Alioune Camara ◽  
Sidikiba Sidibé ◽  
Ibrahima Kaba ◽  
Nestor Niouma Leno ◽  
...  

Introduction: The aim was to assess weight gain during tuberculosis treatment in patients co-infected with tuberculosis and HIV. Methods: Tuberculosis patients co-infected with HIV and undergoing tuberculosis treatment in the pneumophtisiology and infectious and tropical diseases departments of the CHU in Conakry were included. Results: 562 patients were included, with a mean age of 35.6±11.3 years, and 52.5% were women. The average Body Mass Index [BMI] at baseline was 17.8 3.3 kg/m2. 71.5% of patients had a favorable result and 28.5% had an unfavorable result [death, abandonment]. Healed and lost patients gained an average of 2.6 kg and 0.1 kg respectively. Deceased patients lost an average of 3.6 kg. The weight variations of the cured patients were different from those of the deceased [p < 0.001]. A weight gain of 5% after 6 months of treatment was associated with the treatment site [OR=3.81; 95% CI 1.08 to 13.45], alcohol consumption [OR=10.33; 95% CI 1.20 to 89.16], malnutrition before treatment [OR=2.72; 95% CI 1.43 to 5.17] and the form of tuberculosis [OR=3.27; 95% CI 1.15 to 9.33]. Conclusion: Newly diagnosed patients co-infected with TB-HIV at Conakry's CHU are often malnourished. Weight gain during treatment seems to be a reliable indicator of the overall response to treatment.


2021 ◽  
pp. 101053952110005
Author(s):  
Hyunjin Son ◽  
Jeongha Mok ◽  
Miyoung Lee ◽  
Wonseo Park ◽  
Seungjin Kim ◽  
...  

This is a retrospective cohort study using notification data in South Korea. We evaluated the nationwide status, regional differences, and the determinants of treatment outcomes among tuberculosis patients. Treatment success rate improved from 77.0% in 2012 to 86.0% in 2015. The lost to follow-up rate was higher among older people, males, and foreign nationals. Health care facilities designated for the Public-Private Mix (PPM) project showed higher success rate and lower rate of lost to follow-up. Moreover, municipalities with low regional deprivation index had higher PPM project coverage. Since there is a large regional difference in the coverage of the PPM project, an additional community-based support program should be implemented, especially for tuberculosis patients residing in region with low PPM project coverage.


Pharmacy ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 86
Author(s):  
Fauna Herawati ◽  
Yuni Megawati ◽  
Aslichah ◽  
Retnosari Andrajati ◽  
Rika Yulia

The long period of tuberculosis treatment causes patients to have a high risk of forgetting or stopping the medication altogether, which increases the risk of oral anti-tuberculosis drug resistance. The patient’s knowledge and perception of the disease affect the patient’s adherence to treatment. This research objective was to determine the impact of educational videos in the local language on the level of knowledge, perception, and adherence of tuberculosis patients in the Regional General Hospital (RSUD) Bangil. This quasi-experimental study design with a one-month follow-up allocated 62 respondents in the intervention group and 60 in the control group. The pre- and post-experiment levels of knowledge and perception were measured with a validated set of questions. Adherence was measured by pill counts. The results showed that the intervention increases the level of knowledge of the intervention group higher than that of the control group (p-value < 0.05) and remained high after one month of follow-up. The perceptions domains that changed after education using Javanese (Ngoko) language videos with the Community Based Interactive Approach (CBIA) method were the timeline, personal control, illness coherence, and emotional representations (p-value < 0.05). More than 95% of respondents in the intervention group take 95% of their pill compared to 58% of respondents in the control group (p-value < 0.05). Utilization of the local languages for design a community-based interactive approach to educate and communicate is important and effective.


Sign in / Sign up

Export Citation Format

Share Document