Efeitos cicatrizantes e antimicrobianos das plantas medicinais especies Porophyllum ruderale (Arnica), Arctium lappa minor (Bardana) e Plantago major (Tanchagem ou Cinco Nervos)

1991 ◽  
Author(s):  
Domingos Alves de Lima Neto
Keyword(s):  
Plantago Major ◽  
Arctium Lappa

scholarly journals Avaliação da atividade antimicrobiana e citotoxicidade hemolítica em diferentes extratos vegetais

2018 ◽  
Vol 25 (1) ◽  
pp. 11
Author(s):  
Andréia De Haro Moreno ◽  
Lucas Possebon ◽  
Moniele Sant’ana ◽  
Helena Ribeiro Souza ◽  
Melina Misuzaki Iomasa Pilon ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Staphylococcus Aureus ◽  
Pseudomonas Aeruginosa ◽  
Klebsiella Pneumoniae ◽  
Proteus Mirabilis ◽  
Plantago Major ◽  
Arctium Lappa ◽  
Morus Nigra ◽  
Acinetobacter Sp ◽  
Mikania Glomerata

Introdução: A busca por novos agentes terapêuticos tem incentivado as pesquisas com plantas medicinais, pois muitas delas podemapresentar propriedade antimicrobiana e conhecer o potencial citotóxico dos extratos é fundamental para garantir a segurançadurante o uso. Objetivo: Avaliar a atividade antimicrobiana e a citotoxicidade hemolítica de Arctium lappa (bardana), Equisetumarvense (cavalinha), Mikania glomerata (guaco), Morus nigra (amora) e Plantago major (tanchagem), amplamente consumidospela população na forma de chás medicinais. Material e Métodos: Os extratos etanólicos fora preparados a 20% por percolação.Na avaliação antimicrobiana foi utilizada a técnica de difusão em disco, empregando as bactérias Staphylococcus aureus,Escherichia coli, Pseudomonas aeruginosa, Proteus mirabilis, Klebsiella pneumoniae, Acinetobacter sp, Enterococcus sp eSalmonella sp. O ensaio de citotoxicidade baseou-se na exposição dos extratos a 5%, 25%, 50%, 75% e 100% em suspensão dehemácias a 37ºC por 30 minutos, seguido de centrifugação e visualização do grau de hemólise. Resultados: Todos os extratosapresentaram inibição de crescimento microbiano, principalmente sobre Acinetobacter sp (amora), Enterococcus sp (amorae cavalinha), K. pneumoniae (amora, bardana e guaco), P. aeruginosa (cavalinha, tanchagem, bardana e guaco) e Salmonellasp (amora e bardana). No ensaio de citotoxicidade, o grau de hemólise foi classificado como baixo para tanchagem e bardana(5%) e médio para cavalinha, guaco e amora (25%) nas concentrações testadas. Conclusão: Os resultados mostram o potencialantimicrobiano dos extratos de amora, bardana, cavalinha, guaco e tanchagem contra bactérias Gram negativas e a baixacitotoxicidade hemolítica confirma a segurança no uso dos mesmos como agentes terapêuticos.

Антиаритмическое действие флавоноидной фракции экстракта Plantago major L.

2019 ◽  
Vol 52 (12) ◽  
pp. 30-33
Author(s):  
Шункор Садуллаевич Хушматов ◽  
Рустам Расулджанович Махмудов
Keyword(s):  
Plantago Major

Изучено антиаритмическое действие флавоноидной фракции экстракта Plantago major L. (0,05 мг/мл). Установлено, что исследованные фракции подавляют частоту сокращений папиллярной мышцы сердца крысы на фоне аритмии, вызванной аконитином (1 мкМ) в условиях in vitro. Анализируя литературные и полученные данные, можно предположить, что антиаритмический эффект изученных флавоноидных фракций может быть связан с модуляцией функциональной активности Na+- и Са2+-каналов в кардиомиоцитах.

Efficacy of Aloe vera/ Plantago Major Gel in Diabetic Foot Ulcer: A Randomized Double-Blind Clinical Trial

2019 ◽  
Vol 16 (2) ◽  
pp. 223-231 ◽  
Author(s):  
Younes Najafian ◽  
Zahra M. Khorasani ◽  
Mona N. Najafi ◽  
Shokouh S. Hamedi ◽  
Marjan Mahjour ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Diabetic Foot ◽  
Intervention Group ◽  
Aloe Vera ◽  
Foot Ulcer ◽  
Diabetic Foot Ulcer ◽  
Control Group ◽  
Plantago Major ◽  
Double Blind ◽  
Significant Difference

Background:Diabetic foot ulcer (DFU) is one of the most common complications of diabetic patients. Mostly, non-healing DFU leads to infection, gangrene, amputation and even death. High costs and poor healing of the wounds need a new treatment such as alternative medicine. So, the aim of this study was to evaluate the efficacy of Aloe vera/ Plantago major gel (Plantavera gel) in healing of DFUMethods:Forty patients with DFU enrolled in a double-blind randomized clinical trial. The patients who were randomly assigned into the intervention group (n = 20), received topical Plantavera gel in addition to the routine cares, whereas the patients in the control group (n = 20), received topical Placebo gel in addition to the routine cares. Intervention was done twice a day for 4 weeks in the both groups. Photography and an evaluation of DFU healing were conducted by a checklist and then were scored at baseline and at the end of each week. The collected data was analyzed by SPSS software.Results:At the end of the study, there was a significant difference between the two groups in terms of total ulcer score (P<0.001) and Plantavera gel significantly reduced the ulcer surface comparing with the control group (P=0.039). However, there was not a significant difference between the two groups (P=0.263) in terms of the ulcer depth. During this study, no side effect was observed for Plantavera gel in the intervention group.Conclusion:Topical Plantavera gel seems to be an effective, cheap and safe treatment. Of course, further studies are required to confirm the properties of the wound healing of this gel.

Improved Method for Obtaining of Arctigenin from Arctium Lappa L. and its Antiproliferative Effect on Human Hepatocarcinoma HepG2 Cells

2020 ◽  
Vol 16 (3) ◽  
pp. 358-362
Author(s):  
Renan S. Teixeira ◽  
Paulo H.D. Carvalho ◽  
Jair A.K. Aguiar ◽  
Valquíria P. Medeiros ◽  
Ademar A. Da Silva Filho ◽  
...  
Keyword(s):  
Antitumor Activity ◽  
Crude Extract ◽  
Hepg2 Cells ◽  
Liver Carcinoma ◽  
Adhesion Assay ◽  
Dependent Manner ◽  
Concentration Dependent Manner ◽  
Arctium Lappa ◽  
Nih 3T3

Background: Arctigenin is a lignan found in Arctium lappa L. (Asteraceae) that displays anti-inflammatory activities. Previous studies showed that the crude extract of A. Lappa has antitumor activity in human liver carcinoma, lung and stomach cancer cells. The aim of this study was to obtain arctigenin from A. lappa L., as well as to evaluate its antiproliferative effects in cells of liver carcinoma (HepG2) and fibroblasts (NIH/3T3). Methods: Arctigenin was obtained from the hydrolysis of arctiin, which was isolated from the crude extract of A. lappa. The effects of arctigenin and arctiin on HepG2 cell viability and cell adhesion were analyzed by MTT method. Adhesion assay was also carried out to evaluate the antitumor activity. Results: Our results showed that the analytical process to obtain arctigenin was fast and easy. In vitro experiments showed that arctigenin (107-269 μM) decreased HepG2 cells viability and did not cause cytotoxicity on NIH/3T3 cells. Arctigenin (27-269 μM) demonstrated anti-adhesion in HepG2 cells in a concentration-dependent manner, when compared with control. Conclusion: These results suggest a promising pharmacological activity for arctigenin as an antiproliferative compound.

Arctium lappa and management of liver functions to detoxifying the bloodstream

2020 ◽  
Vol 10 ◽  
Author(s):  
Mohaddese Mahboubi
Keyword(s):  
Zinc Oxide ◽  
Carbon Tetrachloride ◽  
Animal Studies ◽  
Main Part ◽  
Liver Enzymes ◽  
Review Article ◽  
Northern Asia ◽  
Arctium Lappa ◽  
Perennial Plant ◽  
Liver Functions

: Arctium lappa or burdock (Compositae family) is a perennial plant, native to Europe, Northern Asia and North America. Burdock roots are known as detoxifying herb to clear toxins from the bloodstream. It seems that its effects are on the liver functions as the main part of body in detoxifying the bloodstream. The aim of this review article was to evaluate the potency of burdock in management of liver functions in detoxifying the bloodstream. The information was extracted from electronic resources (Google scholar, Science Direct, Springer, Magiran). The results of our investigation exhibited that the studies are limited to animal studies, but the results of investigations showed that burdock roots detoxify the liver against ethanol, carbon tetrachloride (CCL4), acetaminophen, cadmium and zinc oxide by improving the functions of liver enzymes. The antioxidant, anti-inflammatory and prebiotic effects of burdock roots may involve in its effects on liver enzymes and detoxifying the blood. The large clinical studies are required to confirm its efficacy on liver functions and detoxify the liver.

Ảnh hưởng của điều kiện ánh sáng và thời gian sinh trưởng lên hàm lượng một số hợp chất trong cây mã đề (Plantago major)

2019 ◽  
Vol 55(5) ◽  
pp. 66
Author(s):  
Nguyễn Văn Ây ◽  
Trần Thanh Mến ◽  
Đỗ Tấn Khang ◽  
Nguyễn Thị Quới Trâm
Keyword(s):  
Plantago Major
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