scholarly journals M.E.S. Abasaheb Garware College, Pune and Arts, Commerce and Science College, Lasalgaon

2021 ◽  
pp. 86-89
Author(s):  
Sujata M. Kasabe ◽  
Bajirao B. Ahire
Keyword(s):  
Blood Plasma ◽  
Human Body ◽  
Calcium Concentration ◽  
The Body ◽  
Ion Concentration ◽  
Human Beings ◽  
Total Calcium ◽  
Chemical Signalling ◽  
Wide Range ◽  
Bone Calcium

During the last decade it became the subject of much attention by both scientists and the general public that in the biological system like many other inorganic elements calcium is the most important element. The central role of calcium is in mammalian bones and other mineralized tissues were recognised immediately after its discovery as an element by the scientist Davy in 1808. The insight arrived much later that calcium 2+ ions could play a very important role in other tissues as well. Nowadays, Ca2+ ions are widely recognised as central to a complex intracellular messenger system that is mediating a wide range of biological processes such as muscle contraction, secretion, glycolysis and glycogenesis, iron transport, cell division and growth [1–11]. In the case of mammals, the blood plasma in the Ca2+ Ion concentration exceeds the intracellular by factor of about 104 Ca2+ ions are instrumental in joining certain proteins in the blood clotting system with membrane surfaces of circulating cells. The stable isotopes of calcium are 40 Ca, 44 Ca, 42 Ca, 43 Ca, amid all 40 Ca is most abundant [12]. There are two main groups of experimental techniques for the measurement ofCa2+ion namely 1) Measurement of free calcium concentration. 2) Measurement of total calcium concentration. Approximately 1 kilogram of calcium is present in the human body of which more than 99% deposit is in the bone in the form of calcium phosphate [1]. The distribution of calcium 2+ Ion throughout the organism is demanded and should be made available where needed. In human beings, the blood plasma level of total calcium is kept constant (=2.45mM) within the narrow limits. On a cellular level the basal cytoplasmic calcium 2+concentration, at least in eukaryotic cells, is very low that is on the order of 100 nM. Whereas, at the same time the concentration of Ca2+ in certain organelles such as endoplasmic reticulum or mitochondria may be considerably higher [2,13]. Ca+ channels are regulated by chemical signalling, perhaps by hormones acting directly on the channel by small molecules released intracellularly when a hormone is attached to a membrane- bound receptor [lipard]. More than 99% of the calcium in the human body is in the bones and teeth. In bone, calcium provides the structural strength that allows the bone to support the body’s weight and anchor the muscles. Bone calcium also serves as a reservoir that can be tapped to maintain extracellular calcium concentration regardless of intake. Calcium differs from most other nutrients in that the body contains a substantial store, far in excess of short-term needs, but at the same time that store serves a critical structural role. Thus, the effects of calcium deficiency may escape notice for a considerable time, until they manifest as skeletal weakness or fractures. Deficiency of calcium bones becomes interstitial or brittle and osteoporosis gradually develops.

Hierarchical Engineering Model of the Human Body

2016 ◽  
Author(s):  
Somayajulu D. Karamchetty
Keyword(s):  
Human Body ◽  
Hierarchical Modeling ◽  
Control Volume ◽  
The Body ◽  
Whole Body ◽  
Operational Parameters ◽  
Sufficient Detail ◽  
Wide Range ◽  
Level Model ◽  
Complex Engineering

Engineers and scientists are able to understand and analyze the behavior of complex engineering systems in a wide range of critical technologies through hierarchical modeling followed by simulation of the model operation. This process results in a high fidelity integrated model as each level in the hierarchy is modeled in sufficient detail. The overall objective of this effort is to develop a sophisticated hierarchical model of the human body, followed by simulation of the model operation. In this initial research phase, the feasibility of the concept is explored and a framework for the model is described. A six-level model consisting of the whole body as a system, system of systems, organs, tissues, cells, and molecules is proposed and described. This paper explains that the human body is amenable to such hierarchical modeling and describes the benefits that can be achieved. The systems in the body deal with numerous processes: electrical, chemical, biochemical, energy conversion, transportation, pumping, sensing, communications, and so on. Control volume models for the organs in the body capture the mass and energy balance and chemical reactions. Tissue can be represented similar to structural components made of various biomaterials. Cells can be represented as a manufacturing and maintenance workforce assisted by molecular reactions. Following the representation of a healthy body, simulation runs by inserting faults and/or deficiencies in the operational parameters into the model could reveal the causes for specific diseases and illnesses. Such modeling and simulation will benefit medical, pharmaceutical, nutritional specialists, and engineers in designing, developing, and delivering products and services to enable humans to lead healthy lives.

scholarly journals Substantial and Substantive Corporeality in the Body Discourses of Bhakti Poets

Perichoresis ◽  
2020 ◽  
Vol 18 (2) ◽  
pp. 73-94
Author(s):  
Yadav Sumati
Keyword(s):  
Human Body ◽  
The Body ◽  
Historical Background ◽  
Spiritual Awakening ◽  
Male Body ◽  
Human Beings ◽  
Medieval Period ◽  
Late Medieval ◽  
Late Medieval Period ◽  
Material Reality

AbstractThis paper studies the representation of human corporeal reality in the discourses of selected Bhakti poets of the late medieval period in India. Considering the historical background of the Bhakti movement and contemporary cultural milieu in which these mystic poets lived, their unique appropriation of the ancient concept of body is reviewed as revolutionary. The focus of the study is the Kabir Bijak, Surdas’s Vinay-Patrika, and Tulsidas’s Vinay-Patrika, wherein they look at and beyond the organic corporeality and encounter human body not as a socially, religiously, economically stamped noble body or lowly body; male body or female body, but a human body. This paper explores how, like existential phenomenologists, these poet/singers decode the material reality of human beings and link it to the highest goal of achieving Moksha (liberation from the cycle of birth-death) by making body a vulnerable but essential instrument towards spiritual awakening. The paper also reflects upon how these poets have suggested a middle path of absolute devotion to God while performing all earthly duties, seek spiritual enlightenment and avoid the extremities of asceticism and hedonism.

Mimi Nichter, Fat talk: What girls and their parents say about dieting. Cambridge, MA: Harvard University Press, 2000. Pp. xi, 263. Hb $22.95.

2002 ◽  
Vol 31 (5) ◽  
pp. 811-815
Author(s):  
Mary Bucholtz
Keyword(s):  
Human Body ◽  
Harvard University ◽  
The Body ◽  
Fat Talk ◽  
Teenage Girls ◽  
Wide Range ◽  
Medical Anthropologist ◽  
The Relationship ◽  
Equal Interest

The relationship between language and the body has become an increasingly prominent area of research within linguistics and related disciplines. Some investigators of this question have examined how facts about the human body are encoded in linguistic structure, while others have explored the use of the body as a communicative resource in interaction. Surprisingly little, however, has been written about the role of language in constructing the body as a social object. In Fat talk, Mimi Nichter, a medical anthropologist, addresses this issue by examining the discourse of dieting among American teenage girls. Although language itself is not the center of the analysis, Nichter draws on a wide range of sociolinguistic research to investigate how the body is constructed through talk – a question that will be of equal interest to scholars of language, culture, and society.

scholarly journals BODY FLUID CHANGES DUE TO CONTINUED LOSS OF THE EXTERNAL SECRETION OF THE PANCREAS

1928 ◽  
Vol 48 (6) ◽  
pp. 859-869 ◽  
Author(s):  
James L. Gamble ◽  
Monroe A. McIver ◽  
Keyword(s):  
Body Weight ◽  
Blood Plasma ◽  
Pancreatic Juice ◽  
Plasma Volume ◽  
Body Fluid ◽  
Chloride Ion ◽  
The Body ◽  
Ion Concentration ◽  
Ionic Content ◽  
Physical Changes

From the data given above the following explanation of the effects of continued loss of the external secretion of the pancreas may be offered. The underlying event is a steadily increasing deficit of sodium and of chloride ion due to the large requirement for these electrolytes in the construction of pancreatic juice. In consequence there is continued loss of water, chiefly from the body fluids in which sodium and chloride ion are large factors of total ionic content, viz., interstitial fluids and the blood plasma. During about two-thirds of the survival period the volume and composition of the blood plasma remain approximately normal, the losses of water, sodium, and chloride ion being replaced at the expense of interstitial fluids. Reduction of the volume of these fluids is indicated by loss of body weight beginning directly after establishment of the pancreatic fistula. Ultimately reduction of plasma volume begins and, as it progresses, serious symptoms develop and death occurs unless water, sodium, and chloride ion are abundantly replaced. Owing to the relatively greater loss of sodium than of chloride ion in pancreatic juice, reduction of bicarbonate ion concentration in the plasma tends to occur. The death of the organism may be simply and reasonably explained as the result of progressive impairment of the function of the blood by the physical changes, dehydration and acidosis, produced in the plasma by the continued loss of sodium and of chloride ion in the pancreatic juice.

scholarly journals ABSTRACT Various body parts or organs can be analysed to identify the different diseases in the human body. Fingernail analysis is one of the ways to identify disease in the human body. Nails are the body part which are farthest from the heart and therefore receive oxygen at last. As a result the nails are the first who show the symptoms of a disease in the human body. Fingernails can be easily captured for diagnosis and there are no heavy equipment or no specific conditions required to use nail image for disease diagnosis, like in other tests and scanning processes. Human nails deliver beneficial information about complaints or any nutritive imbalances in the human body depending upon their shape, texture and colour. In human beings, numerous systemic and skin diseases can be easily analyzed through careful examination of nails of both the limbs. A lot of nail illnesses have been found to be primary signs of numerous underlying systemic illnesses. The colour, texture or shape changes in nails are signs of many diseases mainly affecting nails. Considering all these properties of nails a system is proposed that uses digital image processing (DIP) methods for identifying such changes in the human nail to get more precise results and predict numerous diseases effortlessly. With the emerging Internet of Things (IOT) concept the generated report is made available remotely, this will help users to reduce transportation efforts. As the system has to deal with large and private data, the security of data must be ensured. To keep the data confidential, the Blockchain concept which is one of the most emerging concepts in the field of data management is used. The paper contains the implementation of the digital image processing for feature extraction of nail images, usage of IOT (ThingSpeak cloud) for data storage and implementation of Blockchain to keep the system secured and theft free. KEY WORDS: Int ernet of thin gs (IOT), Image proc essin g, Thin gSpeak, RG B vavalues, Mean pi xel vavalues, Bloc kchain , Hash key. Disease Diagnostic System: Abnormalities in Human Nail

2020 ◽  
Vol 13 (14) ◽  
pp. 452-457
Author(s):  
Pranav S. Wazarkar
Keyword(s):  
Image Processing ◽  
Digital Image Processing ◽  
Human Body ◽  
Digital Image ◽  
Skin Diseases ◽  
Disease Diagnosis ◽  
The Body ◽  
Careful Examination ◽  
Human Beings ◽  
Human Nail

scholarly journals OpenSim scripting: MATLAB and XML

2020 ◽  
Author(s):  
Tanmay Debnath
Keyword(s):  
Human Body ◽  
Broad Spectrum ◽  
The Body ◽  
Human Skeleton ◽  
Skeleton Model ◽  
Wide Range ◽  
Precise Representation ◽  
Sports And Exercise ◽  
Injury Recovery ◽  
Media Lab

Biomechanics is one of the important domains to study and research. There are certain domains within the broad spectrum of biomechanics which is based on the precise representation of the biomechanics of a particular body. Some of the applications of the same are evident in the department of sports and exercise, where the improvement in the biomechanics of the body directly affects the improvement in the game or sport. It is not only related to the study of sports and related mechanics. But it has a wide range of applications in the domain of injury recovery. Worth mentioning, Hugh Herr, the director of the Biomechatronics lab at MIT Media Lab is one of the key people to have established the domain in a way no one could have ever imagined. Using the paradigms of biomechanics and electronics, he revolutionized the mechanics of the human body for those who are required to have some form of body prosthetics.In analyzing the same, we find the usage of the OpenSim to be most crucial and hence, in turn, determine the scripting of the same to be one of the important paradigms to be learned in the same. In this report, I have presented the entire modeling segment of the human skeleton model using OpenSim classes in MATLAB. The code shall be utilized in all versions of MATLAB and can be modified as per requirements.

scholarly journals DETERMINATION OF TERIFLUNOMIDE ACROSS A WIDE DYNAMIC CONCENTRATION RANGE IN HUMAN PLASMA BY LC–MS/MS

2019 ◽  
Vol 16 (32) ◽  
pp. 608-620
Author(s):  
Natalia E. MOSKALEVA ◽  
Natalia V. MESONZHNIK ◽  
Roman M. KUZNETSOV ◽  
Pavel A. MARKIN ◽  
Svetlana A. APPOLONOVA
Keyword(s):  
Blood Plasma ◽  
High Performance ◽  
Plasma Concentrations ◽  
Internal Standard ◽  
The Body ◽  
Human Blood Plasma ◽  
Measured Concentration ◽  
Wide Range ◽  
The Difference ◽  
Acquity Uplc

Leflunomide is an antirheumatic drug with anti-inflammatory and antirheumatic properties, it is rapidly metabolized in the body to the active metabolite teriflunomide, which causes its pharmacological activity. At the usual 20-mg daily dosage of leflunomide, the expected teriflunomide plasma concentration is about 35 μg/ml. The pharmacokinetics of the drug is characterized by a large interindividual variability and a long half-life, which in combination with possible side effects creates the need to control the concentration of teriflunomide in the blood plasma. Teriflunomide may increase the risk of fetal death or teratogenic effects when administered to pregnant women. Teriflunomide plasma concentrations less than 0.02 μg/ml are preferred for patients anticipating pregnancy. In this study, a sensitive and high-performance method for analyzing teriflunomide in human blood plasma in a wide range of concentrations was developed and validated using a triple quadrupole liquid chromatography-mass spectrometer (HPLC-MS/MS). Sample preparation was performed by protein precipitation with acetonitrile, followed by chromatographic separation using an Acquity UPLC BEN C8 1.7 mm, 2.1 × 50 mm column (Waters, USA). D4-teriflunomide was used as an internal standard. The developed method was validated in the concentration range from 0.001 μg/ml to 200 μg/ml teriflunomide in plasma. Accuracy (%), defined as the difference between the nominal and measured concentration and reproducibility (coefficient of variation CV) ranged from -5.02% to 5.00% and from 0.47% to 9.30%, respectively, within the series and between series of samples. The developed method was successfully used to analyze volunteer blood plasma samples after taking 20 mg of leflunomide.

scholarly journals The influence of silicium compounds on the content of calcium, phosphorus and some lipides in the plasma blood

2019 ◽  
Vol 21 (95) ◽  
pp. 41-46 ◽  
Author(s):  
A. I. Ivanitskaya ◽  
Ya. V. Lesyk
Keyword(s):  
Body Weight ◽  
Organic Compound ◽  
Blood Plasma ◽  
Study Groups ◽  
Sodium Metasilicate ◽  
Inorganic Phosphorus ◽  
The Body ◽  
Control Group ◽  
Total Calcium ◽  
Preparatory Period

The aim of the study was to investigate the effects of nanotechnology and sodium metasilicate on the content of total calcium and inorganic phosphorus and individual lipids in the blood of rabbits from 52 to 110 days of life. Studies were conducted on young rabbits of Hyla breed in the private sector. Rabbits for the study were selected at the age of 41 days on the principle of analogues, weighing 1.2–1.4 kg, were divided into six groups (control and five experimental), 6 animals (3 males and 3 females) in each. Animals were kept in with adjustable microclimate and illumination in mesh cages measuring 50×120×30 cm, in accordance with modern animal health standards. The control group rabbits were fed without restriction a balanced granular compound feed, with free access to water. Animals I, II, and III of the study groups were fed a control group diet and fed citrate silicon for 24 hours, with a corresponding rate of 25; 50 and 75 µg Si/kg body weight. Young animals of the IV and V experimental groups were fed wit diet of the control group and water was given sodium metasilicate (Na2SiO3H2O) in the amount of 2.5 and 5.0 mg Si/kg body weight, respectively. The experiment lasted 68 days, including the preparatory period of 10 days, the experimental period – 58 days. In the preparatory period – at 52 days and experimental at 83 and 110 days of life (31 and 58 days of drinking additives) in 4 animals (2 males and 2 females) from the group blood samples were taken for biochemical studies. Studies have found that the concentration of total calcium in the blood plasma of rabbits III and IV study groups was higher by 9.6 and 6.4% (P < 0.05) for 58 days of the study compared with the control, indicating the stimulating effect of the organic compound silicon to activate the processes of assimilation of this macronutrient in the body of young rabbits. Silicone citrate in the large test quantities and sodium metasilicate in the blood plasma of animals of III, IV and V experimental groups respectively increased the level of inorganic phosphorus by 35.7; 28.5 and 35.7% (P < 0.05) than controls at day 58 of the study. In the final study period, the ratio of Calcium to Phosphorus in the animals of the II – V experimental groups was in the range of 2.0–1.73: 1, indicating a more pronounced effect of silicon compounds on the metabolism of Phosphorus during a longer period of supplementation. The content of triacylglycerols in the blood plasma of rabbits II and III of the experimental groups was lower (P < 0.05) at 31 and 58 days of the study compared with the control. The results obtained may indicate the activation of the processes of metabolic accumulation of plastic components of cell membranes and energy needs of body tissues. The use of silica organic compound reduced the cholesterol content by 37% (P < 0.05) in the blood of rabbits of the III experimental group at 31 days of the study. Whereas at the final stage of the experiment in animals II; In the 3rd and 4th research groups, its level was lower by 43.4; 36.9 and 42.2% (P < 0.05) compared to the control, indicating greater use of cholesterol by the organism with silica organic compound.

scholarly journals Μισέλ Φουκώ: Η συγκρότηση του σύγχρονου πειθαρχικού υποκειμένου

Conatus ◽  
2017 ◽  
Vol 1 (1) ◽  
pp. 41
Author(s):  
Θάνος Κιοσόγλου (Thanos Kiosoglou)
Keyword(s):  
Everyday Life ◽  
Human Body ◽  
The Body ◽  
The Political ◽  
Human Being ◽  
Human Beings ◽  
Present Account ◽  
The Reformation ◽  
The Everyday ◽  
Political Technology

In his seminal Discipline and Punish: The Birth of the Prison, Michel Foucault aims at outlining the historical course that led to the promulgation and consolidation of the institution of imprisonment as a means of punishment as well as narrating how the corresponding human type, i.e. the contemporary disciplined subject, has been shaped. Obviously, the disciplined subject gradually took the place of the tormented subject. Consequently, this study aims at describing the sequential mutations of the imposed punishment as it progressively shifted from the spectacular slaughtering of the body to the strictly scientific manipulation of the non-material dimension of the human being. The reformation of the punitive practices “constructs” a docile body. It must be noticed, however, that this body is not necessarily guilty, since the disciplinary schemes concern everybody, even the most innocent sides of the everyday life as for example the hospital, the school or the barracks. Additionally, discipline is imposed through the division of the space, what Foucault calls the “art of allocation”, so that every working person is easily seen and supervised by the eye of the authority, while the disciplined subject is being forged gradually through the sense of responsibility before the flowing time. Foucault highlights the “political technology of the body”, that is its usurpation by the authorities, who aim at imposing to it adictated activity that produces palpable results in a binding frame of time. Although selective and brief, the present account of the punitive concepts of the three last centuries clarifies the fact that the authoritarian strategies are indissolubly interwoven with the different connotations of the human body, through the use of which they subdue human beings.

scholarly journals The nature, function, and destiny of the human body—Origen’s interpretation of 1 Cor 15

2019 ◽  
Vol 23 (1) ◽  
pp. 36-52
Author(s):  
Anders-Christian Jacobsen
Keyword(s):  
Human Body ◽  
First Principles ◽  
The Body ◽  
Human Beings

Abstract In this article, I will investigate Origen’s use of two metaphors: The seed metaphor and the clothing metaphor. Both metaphors are found in Paul’s first letter to the Corinthians, which Origen uses as his biblical foundation in the passage from On First Principles that will be analyzed in this article. My focus will be on how Origen understands the nature, the function, and the destiny of human beings and especially of human bodies. According to Origen, the nature of the human body is changeable and unstable. This is because the bodily matter has merely been added to the rational beings at a certain time and will disappear again when its function is fulfilled. The function of the human body is to clothe the rational being on its way through fall and spiritual progress towards perfection. Thus, the body allows the rational being to be punished and educated. The destiny of the human body is eventually to disappear, but this will only happen when the body has gone through many stages of fall and progress in its service of the rational being.

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