scholarly journals Jorge Oteiza y Mariano Garrigues en el INIA (1951-57): un cruce de dos modernidades

2019 ◽  
Vol 6 (2) ◽  
pp. 121
Author(s):  
Carlos Labarta Aizpún ◽  
Eduardo Delgado Orusco

The fruitful decade of the nineteen-fifties, although a widely studied period, harbours unexpected eventualities, such as the confluence of a resolutely experimental sculptor and an architect of a more possibilistic nature. The circumstances surrounding the encounter and revelation of this joint work, very rarely mentioned in the corresponding literature, can be seen as an event that contributes to verifying, once again, the multi-faceted soul of the modern movement in Spain, whose fruitfulness was a result of its inherent hybridity, strengthened by the challenge of creating any classification. In this case, it is concluded that Oteiza’s piece, the result of his investigation into the spatial implications of the wall, is juxtaposed against the building by Garrigues without achieving a real dialogue with the incipient modernism in the architecture of the institute.

2019 ◽  
Author(s):  
Zichen Wang ◽  
Huaxun Fan ◽  
Xiao Hu ◽  
John Khamo ◽  
Jiajie Diao ◽  
...  

<p>The receptor tyrosine kinase family transmits signals into cell via a single transmembrane helix and a flexible juxtamembrane domain (JMD). Membrane dynamics makes it challenging to study the structural mechanism of receptor activation experimentally. In this study, we employ all-atom molecular dynamics with Highly Mobile Membrane-Mimetic to capture membrane interactions with the JMD of tropomyosin receptor kinase A (TrkA). We find that PIP<sub>2 </sub>lipids engage in lasting binding to multiple basic residues and compete with salt bridge within the peptide. We discover three residues insertion into the membrane, and perturb it through computationally designed point mutations. Single-molecule experiments indicate the contribution from hydrophobic insertion is comparable to electrostatic binding, and in-cell experiments show that enhanced TrkA-JMD insertion promotes receptor ubiquitination. Our joint work points to a scenario where basic and hydrophobic residues on disordered domains interact with lipid headgroups and tails, respectively, to restrain flexibility and potentially modulate protein function.</p>


2018 ◽  
Vol 84 (12) ◽  
pp. 61-67
Author(s):  
V. A. Eryshev

The mechanical properties of a complex composite material formed by steel and hardened concrete, are studied. A technique of operative quality control of new credible concrete and reinforcement, both in laboratory and field conditions is developed for determination of the strength and strain characteristics of materials, as well as cohesion forces determining their joint operation under load. The design of the mobile unit is presented. The unit provides a possibility of changing the direction of loading and testing the reinforced element of the given shape both for tension and compression. Moreover, the nomenclature of testing equipment and the number of molds for manufacturing concrete samples substantially decrease. Using the values of forcing resulting in concrete cracking when the joint work of concrete and reinforcement is disrupted the values of the inherent stresses and strains attributed to the concrete shrinkage are determined. An analytical relationship between the forces and deformations of the reinforced concrete sample with central reinforcement is derived for axial tension and compression, with allowance for strains and stresses in the reinforcement and concrete resulted from concrete shrinkage. The results of experimental studies are presented, including tension diagrams and diagrams of developing axial deformations with an increase in the load under the central loading of the reinforced elements. A methodology of accounting for stresses and deformations resulted from concrete shrinkage is developed. The applicability of the derived analytical relationships between stresses and deformations on the material diagrams to calculations of the reinforced concrete structures in the framework of the deformation model is estimated.


Author(s):  
Elena A. Kosovan ◽  

The paper provides a review on the joint Russian-Belarusian tutorial “History of the Great Patriotic War. Essays on the Shared History” published for the 75th anniversary of the victory in the Great Patriotic War. The tutorial was prepared within the project “Belarus and Russia. Essays on the Shared History”, implemented since 2018 and aimed at publishing a series of tutorials, which authors are major Russian and Belarusian historians, archivists, teachers, and other specialists in human sciences. From the author’s point of view, the joint work of specialists from the Russian Federation and the Republic of Belarus in such a format not only contributes to the deepening of humanitarian integration within the Union state, but also to the formation of a common educational system on the scale of the Commonwealth of Independent States or the Eurasian integration project (Eurasian Economic Union – EEU). The author emphasises the high research and educational significance of the publication reviewed when noting that the teaching of history in general and the history of the Second World War and the Great Patriotic War in particular in post-Soviet schools and institutes of higher education is complicated by many different issues and challenges (including external ones, which can be regarded as information aggression by various extra-regional actors).


Author(s):  
Е. N. Sedov ◽  
T. V. Yanchuk ◽  
S. А. Korneeva ◽  
L. I. Dutova ◽  
Е. V. Ulianovskaya

The experience in cooperation of breeders of different institutions in creating cultivars is shown. It is not always when the breeding institution has the necessary initial forms for selection. In this regard, there is a need to conduct separate stages of selection in different breeding institutions. For this purpose, a provision on authorship and continuity in the integrated work of several institutions in fruit breeding has been developed (Program and methods of fruit, berry and nut crop breeding. Annex. – Orel, 1995. – pp. 492-498). Breeding work of the Russian Research Institute of Fruit Crop Breeding (VNIISPK) and North Caucasian Federal Scientific Center of Horticulture, Viticulture, Winemaking can serve as a positive experience of creating new apple cultivars by two institutions. As a result of the joint work of these two institutions, 22 apple cultivars have been created, of which 9 have already been included in the state register of breeding achievements approved for use (zoned), including three cultivars for the conditions of the Middle zone of Russia – Aleksandr Boiko, Maslovskoye and Yablochny Spas and six cultivars for the conditions of the North Caucasus – Vasilisa, Karmen, Margo, Orfey, Soyuz and Talisman. Brief economical and biological characteristics of these cultivars are given in this paper. The obtained practical results indicate that in some cases, when creating modern cultivars that meet the requirements of production, it is necessary to use the knowledge of breeders, the source material and equipment of different breeding institutions, and carry out separate stages of the selection process in different institutions.


Author(s):  
Aisha A. Upton ◽  
Joyce M. Bell

This chapter examines women’s activism in the modern movement for Black liberation. It examines women’s roles across three phases of mobilization. Starting with an exploration of women’s participation in the direct action phase of the U.S. civil rights movement (1954–1966), the chapter discusses the key roles that women played in the fight for legal equality for African Americans. Next it examines women’s central role in the Black Power movement of 1966–1974. The authors argue that Black women found new roles in new struggles during this period. The chapter ends with a look at the rise of radical Black feminism between 1974 and 1980, examining the codification of intersectional politics and discussing the continuation of issues of race, privilege, and diversity in contemporary feminism.


Gerontology ◽  
2021 ◽  
pp. 1-11
Author(s):  
Rebecca L. Krupenevich ◽  
Owen N. Beck ◽  
Gregory S. Sawicki ◽  
Jason R. Franz

Older adults walk slower and with a higher metabolic energy expenditure than younger adults. In this review, we explore the hypothesis that age-related declines in Achilles tendon stiffness increase the metabolic cost of walking due to less economical calf muscle contractions and increased proximal joint work. This viewpoint may motivate interventions to restore ankle muscle-tendon stiffness, improve walking mechanics, and reduce metabolic cost in older adults.


Processes ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 395
Author(s):  
Feng Cheng ◽  
Boqing Ding ◽  
Xiuwei Li

An absorption air-conditioning system is a good choice for green buildings. It has the superiority in the utilization of renewable energy and the refrigerant is environment-friendly. However, the performance of the traditional absorption system has been restricted by the energy waste in the thermal regeneration process. Capacitive deionization (CDI) regeneration is proposed as a potential method to improve system efficiency. In the new method-based air-conditioning system, strong absorbent solutions and pure water are acquired with the joint work of two CDI units. Nevertheless, the practical CDI device is composed of a lot of CDI units, which is quite different from the theoretical model. To reveal the performance of multiple CDI units, the model of the double/multi-stage CDI system has been developed. Analysis has been made to expose the influence of some key parameters. The results show the double-stage system has better performance than the single-stage system under certain conditions. The coefficient of performance (COP) could exceed 4.5, which is higher than the traditional thermal energy-driven system, or even as competitive as the vapor compression system. More stages with proper voltage distribution better the performance. It also provides the optimization method for the multi-stage CDI system.


2020 ◽  
Vol 13 (1) ◽  
pp. 235
Author(s):  
Fernando Martín-Consuegra ◽  
Fernando de Frutos ◽  
Ignacio Oteiza ◽  
Carmen Alonso ◽  
Borja Frutos

This study quantified the improvement in energy efficiency following passive renovation of the thermal envelope in highly inefficient residential complexes on the outskirts of the city of Madrid. A case study was conducted of a single-family terrace housing, representative of the smallest size subsidized dwellings built in Spain for workers in the nineteen fifties and sixties. Two units of similar characteristics, one in its original state and the other renovated, were analyzed in detail against their urban setting with an experimental method proposed hereunder for simplified, minimal monitoring. The dwellings were compared on the grounds of indoor environment quality parameters recorded over a period covering both winter and summer months. That information was supplemented with an analysis of the energy consumption metered. The result was a low-cost, reasonably accurate measure of the improvements gained in the renovated unit. The monitoring output data were entered in a theoretical energy efficiency model for the entire neighborhood to obtain an estimate of the potential for energy savings if the entire urban complex were renovated.


Author(s):  
Michael Atiyah ◽  
Matilde Marcolli

Abstract This paper, completed in its present form by the second author after the first author passed away in 2019, describes an intended continuation of the previous joint work on anyons in geometric models of matter. This part outlines a construction of anyon tensor networks based on four-dimensional orbifold geometries and braid representations associated with surface-braids defined by multisections of the orbifold normal bundle of the surface of orbifold points.


Author(s):  
Miriam Luhnen ◽  
Sari Susanna Ormstad ◽  
Anne Willemsen ◽  
Chaienna Schreuder-Morel ◽  
Catharina Helmink ◽  
...  

Abstract Objectives The European Network for Health Technology Assessment (EUnetHTA) was established in 2006 and comprises over eighty organizations from thirty European countries. In its fifth project phase (Joint Action 3), EUnetHTA set up a quality management system (QMS) to improve the efficiency and standardization of joint work. This article presents EUnetHTA's new QMS and outlines experiences and challenges during its implementation. Methods Several working groups defined processes and methods to support assessment teams in creating high-quality assessment reports. Existing guidelines, templates, and tools were refined and missing parts were newly created and integrated into the new QMS framework. EUnetHTA has contributed to Health Technology Assessment (HTA) capacity building through training and knowledge sharing. Continuous evaluation helped to identify gaps and shortcomings in processes and structures. Results Based on a common quality management concept and defined development and revision procedures, twenty-seven partner organizations jointly developed and maintained around forty standard operating procedures and other components of the QMS. All outputs were incorporated into a web-based platform, the EUnetHTA Companion Guide, which was launched in May 2018. Concerted efforts of working groups were required to ensure consistency and avoid duplication. Conclusions With the establishment of a QMS for jointly produced assessment reports, EUnetHTA has taken a significant step toward a sustainable model for scientific and technical collaboration within European HTA. However, the definition of processes and methods meeting the numerous requirements of healthcare systems across Europe remains an ongoing and challenging task.


Sign in / Sign up

Export Citation Format

Share Document