scholarly journals Serum Uric Acid as a Prognostic Marker of Pregnancy induced Hypertension

2012 ◽  
Vol 4 (3) ◽  
pp. 130-133 ◽  
Author(s):  
Disha Sahijwani ◽  
Ajesh Desai ◽  
Hina Oza ◽  
Vijay Kansara ◽  
Pallavi Ninama ◽  
...  
Keyword(s):  
Uric Acid ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Serum Uric Acid ◽  
Prognostic Marker ◽  
Gestational Hypertension ◽  
Pregnancy Induced Hypertension ◽  
Maternal Complications ◽  
Induced Hypertension ◽  
Laboratory Changes

ABSTRACT Objectives The purpose of the study is to determine the level of serum uric acid (s. uric acid) above which all complications occur, to analyze the maternal and fetal clinical and laboratory changes associated with elevated s. uric acid, and to determine whether s. uric acid can be used to predict maternal and fetal complications. Design A retrospective study of hospital records was done on 80 women of pregnancy induced hypertension including both gestational hypertension and preeclampsia from January 2011 to March 2012 at Civil Hospital, Ahmedabad. The women were divided in two groups: with s. uric acid > 6 mg/dl/ s. uric acid < 6 mg/dl. Results S. uric acid > 6 mg/dl was associated with maternal complications while s. uric acid > 5.5 mg/dl was associated with low birth weight babies. The mean creatinine and platelet count in two groups were significantly different at 5% level. Statistically significant elevation of s. uric acid was found in women of eclampsia. Conclusion S. uric acid > 6 mg/dl is associated with increased maternal complications specially eclampsia and higher incidence of low birth weight. Thus, women with pregnancy induced hypertension with s. uric acid > 6 mg/dl should be offered termination of pregnancy. How to cite this article Sahijwani D, Desai A, Oza H, Kansara V, Ninama P, Maheshwari K, Soni C, Padhiyar B. Serum Uric Acid as a Prognostic Marker of Pregnancy induced Hypertension. J South Asian Feder Obst Gynae 2012;4(3):130-133.

scholarly journals Effect of raised serum uric acid level on perinatal and maternal outcome in cases of pregnancy-induced hypertension

2017 ◽  
Vol 10 (2) ◽  
pp. 58 ◽  
Author(s):  
Qumrun Nassa Ahmed ◽  
Farhana Dewan
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Pregnancy Induced Hypertension ◽  
Maternal Complications ◽  
Induced Hypertension ◽  
Group A ◽  
Group B

<p>The aim of this study was to find out the effects of raised serum uric acid level on perinatal and maternal outcome in cases of pregnancy-induced hypertension. One hundred pregnant women with gestational period beyond 28 weeks with pregnancy-induced hypertension-preeclampsia and eclampsia were included in this study and divided into two groups. Group A (n=65) patients with a serum uric acid level &gt;6 mg/dL was compared to Group B (n=35) patients with a uric acid level &lt;6 gm/dL. It revealed that high uric acid level in patients with pregnancy-induced hypertension was a risk factor for several maternal complications like postpartum hemorrhage (Group A, 17.4%; Group B, 22.6%), postpartum eclampsia (Group A, 10.1%; Group B, 9.7%), abruptio placentae (Group A, 8.7%; Group B, 6.4%), HELLP syndrome (Group A, 2.9%; Group B, 0%) and pulmonary edema (Group A, 4.3%; Group B, 0%). In case of perinatal outcome, the birth weight, intrauterine growth retardation, intrauterine death, stillbirth and neonatal death rate were worse in Group A 1.9 kg, 66.7, 19, 7 and 8% in comparison to Group B, where those were 2.1, 13, 6, 2, and 2% respectively. In conclusion, high uric acid in blood in patient with hypertensive disorders in pregnancy is a risk factor for several maternal complications.</p>

scholarly journals A retrospective study of the health profile of neonates of mothers with anemia in pregnancy and pregnancy induced hypertension in Lagos, Nigeria

2014 ◽  
Vol 5 (2) ◽  
Author(s):  
Olusola Funmilayo Sotunde ◽  
Silifat Ajoke Sanni ◽  
Oluseye Olusegun Onabanjo ◽  
Ibiyemi O. Olayiwola ◽  
Mure Agbonlahor
Keyword(s):  
Retrospective Study ◽  
Birth Weight ◽  
Sampling Technique ◽  
Neonatal Health ◽  
Pregnancy Induced Hypertension ◽  
Health Profile ◽  
Maternal Complications ◽  
Induced Hypertension ◽  
Anemia In Pregnancy ◽  
In Pregnancy

Our study assessed the health profile of neonates in relation to anemia in pregnancy and pregnancy induced hypertension (PIH). This was a retrospective study where a systematic random sampling technique was used to select a total of 1046 case records of pregnant women registered for ante-natal care at Lagos Island Maternity Hospital, Lagos, Nigeria, between 2005 and 2009. Socio-demographic characteristics of the mothers, prevalence of anemia and PIH, and neonatal health profile were obtained from the case records and were analyzed using both descriptive and inferential statistics. Pearson product moment correlation was used to show the relationship (P≤0.05) between maternal complications and neonatal health profile. Majority (68.8%) of the mothers had anemia and 6.7 % had PIH. Majority (97.12%) of the neonates were live births and 2.88% of the neonates were still births, 65.4% of the women with still birth pregnancy outcome had anemia, and 34.6% had PIH. Majority (74%) of the neonates had birth weight within normal range (2.5-4.0 kg) and majority (68%) had normal Apgar score at 5 min of birth (7- 10). A positive correlation existed between the packed cell volume of the mother and the birth weight of the neonates (r=0.740, P≤0.05). A negative correlation existed between the incidence of PIH and the birth weight of the neonates (r=

Abstract 135: Impaired Autonomic Function in Young Adults Born Preterm With Very Low Birth Weight is Associated With Elevated Serum Uric Acid Levels

Hypertension ◽  
2018 ◽  
Vol 72 (Suppl_1) ◽  
Author(s):  
Hossam A Shaltout ◽  
Patricia A Nixon ◽  
Mark C Chappell ◽  
Debra I Diz ◽  
Andrew M South ◽  
...  
Keyword(s):  
Young Adults ◽  
Uric Acid ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Serum Uric Acid ◽  
Autonomic Function ◽  
Very Low Birth Weight ◽  
Elevated Serum

scholarly journals Association of Hyperuricaemia with Perinatal Outcome in Pregnancy Induced Hypertension

2015 ◽  
Vol 32 (3) ◽  
pp. 124-129
Author(s):  
Saida Akter ◽  
Sharmin Sultana ◽  
Seema Rani Dabee
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Uric Acid Level ◽  
Perinatal Outcome ◽  
Acid Level ◽  
Serum Uric Acid Level ◽  
Pregnancy Induced Hypertension ◽  
Group I ◽  
Induced Hypertension ◽  
Group Ii

The high serum uric acid concentration correlates with the degree of severity of the pregnancy induced hypertension (PIH) and perinatal outcome. In this context, maternal serum uric acid level is reported to be one of the prognostic factor for determination of perinatal outcome. Based on the existing data, the present prospective study was undertaken in the Department of Obstetrics and Gynaecology, BIRDEM Academy, from January to December, 2010. Out of 120 women, 60 suffering from PIH (severe preeclampsia and eclampsia) served as group I and 60 normotensive women at third trimester of pregnancy served as group II. This study showed that mean (±SD) serum uric acid was significantly elevated in group I PIH patients (7.21±1.81 mg/dl) compared to group II normotensive pregnancy (4.40±0.84 mg/dl). In group I PIH patients, 39 (86%) had adverse perinatal outcome (preterm, IUGR, stillbirth), and 6 (13.3%) term and healthy deliveries when serum uric acid level was >6 mg/dl. Current study showed that there was positive and statistically significant relationship between diastolic blood pressure and hyperuricaemia in group I PIH patients (r = +0.359, P<0.01). This study also showed that in group I PIH patients, when serum uric acid increased, birth weight significantly decreased (r = 0.279, P<0.05).J Bangladesh Coll Phys Surg 2014; 32: 124-129

scholarly journals Comparison of risk factors for low birth weight among mothers with normal and low birth weight babies

2020 ◽  
Vol 14 (1) ◽  
pp. 1-6
Author(s):  
Vinodkumar Mugada ◽  
Raj Kiran Kolakota ◽  
Abhilasha Sakalabathula ◽  
Bindu Pavani Kola
Keyword(s):  
Risk Factors ◽  
Weight Gain ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Statistical Significance ◽  
Pregnancy Induced Hypertension ◽  
Normal Birth Weight ◽  
Normal Birth ◽  
Low Birth Weight Babies ◽  
Induced Hypertension

Background: Low birth weight is an alarming problem in developing countries and has severe future complications. Aim of the study: Our study aimed to compare the risk factors among mothers with low and normal birth weight babies. Materials and Methods: A cross-sectional study was carried out on 1000 mothers with normal and low birth weight babies (500 per group) over two years. Maternal parameters including age, hemoglobin levels, gravida, maternal weight gain, height, pregnancy-induced hypertension, etc., were collected along with anthropometric data of the child. We compared risk factors among the low and normal birth weight babies using the chi-square test, determining statistical significance at p<0.05, and high statistical significance at p<0.01. Results: Highly statistically significant associations were observed between low birth weight and seven variables: maternal age (p=0.0074), maternal height (p<0.0001), weight (p<0.0001), weight gain (p<0.0001), hemoglobin (p<0.0001), severe anemia (p<0.0001), and pregnancy-induced hypertension (p<0.0001). Conclusion: Our study observed significant modifiable risk factors like weight gain, weight, hemoglobin, and anemia among mothers with low birth weight babies. If we focus on raising awareness surrounding these risk factors, there may be an improvement in the birth weight of babies in this population.

scholarly journals Significance of serum uric acid in toxemia and pregnancy-induced hypertension

2008 ◽  
Vol 32 (2) ◽  
pp. 147-154
Author(s):  
Iwao Ohno ◽  
Yuichiro Yamaguchi ◽  
Hajime Saikawa ◽  
Daijiro Uetakeo ◽  
Miho Hikita ◽  
...  
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Pregnancy Induced Hypertension ◽  
Induced Hypertension

Meta-Analysis Finds Use of Inhaled Corticosteroids During Pregnancy Safe: A Systematic Meta-Analysis Review

2006 ◽  
Vol 25 (8) ◽  
pp. 447-452 ◽  
Author(s):  
R Rahimi ◽  
S Nikfar ◽  
M Abdollahi
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Inhaled Corticosteroids ◽  
Birth Outcome ◽  
Meta Analysis ◽  
Perinatal Outcomes ◽  
Pregnancy Induced Hypertension ◽  
Drug Of Choice ◽  
Term Delivery ◽  
Induced Hypertension

Inhaled corticosteroids (ICs) are the drug of choice for asthmatic women during pregnancy, but the results on the effects of these medications on obstetrical and perinatal outcomes are not conclusive. Meta-analysis is the statistical analysis of a collection of analysis results from individual studies for the purpose of integrating the findings. Meta-analysis techniques are necessary because only summary statistics are available in the literature. In order to determine the risk of exposure to ICs, we pooled data from all clinical studies that evaluated the pregnancy and perinatal outcomes in women exposed to this group of drugs during pregnancy by the meta-analytic technique. PUBMED, OVID, EMBASE and SCOPUS databases were searched for studies that investigated birth outcome following exposure to ICs during pregnancy. Data were collected from 1997 to 2005 (up to 31 December). Types of outcome investigated were major malformations, pre-term delivery, low birth weight and pregnancy-induced hypertension. The criteria for inclusion of studies in this meta-analysis were exposure of women to any therapeutic dosage of any ICs (fluticasone, beclomethasone, budesonide, triamcinolone and flunisolide) during pregnancy. The results showed that ICs do not increase the risk of major malformations, preterm delivery, low birth weight and pregnancy-induced hypertension. In conclusion, ICs do not increase the rates of any obstetrical outcomes investigated in the present study and interestingly improve the symptoms and are helpful in the management of asthma and thus can be used comfortably during pregnancy.

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