A retrospective study of the health profile of neonates of mothers with anemia in pregnancy and pregnancy induced hypertension in Lagos, Nigeria

Our study assessed the health profile of neonates in relation to anemia in pregnancy and pregnancy induced hypertension (PIH). This was a retrospective study where a systematic random sampling technique was used to select a total of 1046 case records of pregnant women registered for ante-natal care at Lagos Island Maternity Hospital, Lagos, Nigeria, between 2005 and 2009. Socio-demographic characteristics of the mothers, prevalence of anemia and PIH, and neonatal health profile were obtained from the case records and were analyzed using both descriptive and inferential statistics. Pearson product moment correlation was used to show the relationship (P≤0.05) between maternal complications and neonatal health profile. Majority (68.8%) of the mothers had anemia and 6.7 % had PIH. Majority (97.12%) of the neonates were live births and 2.88% of the neonates were still births, 65.4% of the women with still birth pregnancy outcome had anemia, and 34.6% had PIH. Majority (74%) of the neonates had birth weight within normal range (2.5-4.0 kg) and majority (68%) had normal Apgar score at 5 min of birth (7- 10). A positive correlation existed between the packed cell volume of the mother and the birth weight of the neonates (r=0.740, P≤0.05). A negative correlation existed between the incidence of PIH and the birth weight of the neonates (r=

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The Effect of Lupus Nephritis on Pregnancy Outcome and Fetal and Maternal Complications

The Journal of Rheumatology ◽

10.3899/jrheum.090872 ◽

2010 ◽

Vol 37 (4) ◽

pp. 754-758 ◽

Cited By ~ 81

Author(s):

DAFNA D. GLADMAN ◽

ANU TANDON ◽

DOMINIQUE IBAÑEZ ◽

MURRAY B. UROWITZ

Keyword(s):

Lupus Nephritis ◽

Renal Disease ◽

Pregnancy Outcome ◽

Repeated Measures ◽

Fetal Outcome ◽

Pregnancy Induced Hypertension ◽

Maternal Complications ◽

Induced Hypertension ◽

Fetal Complications ◽

In Pregnancy

Objective.To evaluate the effect of lupus nephritis on pregnancy with respect to fetal outcome, maternal complications, and lupus activity.Methods.All pregnancies seen between 1970 and 2003 in the Lupus Clinic were evaluated for the 3 outcomes. Renal disease was defined as the presence of nephrotic syndrome, dialysis, renal transplant, serum creatinine > 120 mmol/l, proteinuria, sterile hematuria and pyuria, or the presence of casts. Fetal complications were evaluated in pregnancies resulting in either live births or stillbirths. Generalized estimating equations were used to test for differences in outcomes between pregnancies with and without the presence of active renal disease. Repeated measures adjustments were made in the model for multiple pregnancies in the same mother.Results.There were 193 pregnancies in 104 women. Of these, 81 occurred in the presence of active renal disease during the study period, defined as 6 months prior to conception until the date of pregnancy outcome. One hundred twelve pregnancies were defined as nonrenal. No statistical difference was found in pregnancy outcome. Fetal complications were not different between the 2 groups with the exception of low birth weight and congenital malformations, which were observed more frequently in the renal group. Pregnancy-induced hypertension was more frequent in pregnancies with renal disease. Lupus flares were also more likely to occur in pregnancies with renal disease compared to those without.Conclusion.Lupus nephritis in pregnancy does not lead to worsened pregnancy or fetal outcomes. Active renal disease, however, is associated with pregnancy-induced hypertension, as well as a flare of lupus activity during pregnancy.

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[PP.24.14] PREDICTIVE VALUE OF ANEMIA AND HYPOCHROMIA FOR LOW BIRTH WEIGHT, GESTATIONAL AGE AND POOR APGAR SCORE IN PREGNANCY INDUCED HYPERTENSION

Journal of Hypertension ◽

10.1097/01.hjh.0000492107.72755.7a ◽

2016 ◽

Vol 34 ◽

pp. e264-e265

Author(s):

I. Mozos ◽

R. Nitu ◽

Z. Popa ◽

M. Craina

Keyword(s):

Birth Weight ◽

Low Birth Weight ◽

Gestational Age ◽

Apgar Score ◽

Predictive Value ◽

Pregnancy Induced Hypertension ◽

Induced Hypertension ◽

In Pregnancy

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A retrospective study of socio-demographic factors in pregnancy induced hypertension in a tertiary care hospital in eastern India

International Journal of Clinical Obstetrics and Gynaecology ◽

10.33545/gynae.2019.v3.i1b.14 ◽

2019 ◽

Vol 3 (1) ◽

pp. 78-81

Author(s):

Pratibha Jena ◽

Sudeep Mohapatra

Keyword(s):

Retrospective Study ◽

Tertiary Care Hospital ◽

Tertiary Care ◽

Demographic Factors ◽

Care Hospital ◽

Pregnancy Induced Hypertension ◽

Eastern India ◽

Induced Hypertension ◽

Socio Demographic Factors ◽

In Pregnancy

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Maternal And Fetal Outcome Following Severe Anaemia In Pregnancy: Results From Nobel Medical College Teaching Hospital, Biratnagar, Nepal.

Journal of Nobel Medical College ◽

10.3126/jonmc.v2i1.7668 ◽

2013 ◽

Vol 2 (1) ◽

pp. 22-26

Author(s):

Ram Hari Ghimire ◽

Sita Ghimire

Keyword(s):

Birth Weight ◽

Postpartum Haemorrhage ◽

Fetal Death ◽

Severe Anaemia ◽

Exposed Group ◽

Intrauterine Fetal Death ◽

Pregnancy Induced Hypertension ◽

Medical College ◽

Induced Hypertension ◽

In Pregnancy

Background: anaemia is a major contributor to maternal death in developing countries. Since it reduces resistance to blood loss, death may occur from bleeding associated with normal delivery. Objective: To explore the association between anaemia and maternal and perinatal complications. Study Design: Retrospective cohort study. Materials and Methods: 100 pregnant women admitted for delivery and having severe anaemia were studied and compared with 100 non anaemic women matched for age, parity, and gestational age. Adverse outcomes analysed were: pregnancy induced hypertension, Postpartum haemorrhage hypertension, Abruptio Placenta,, Infection, Maternal Mortality, Low Birth Weight, and Perinatal mortality. Results : Compared to nonexposed women, exposed women had an increased risk of pregnancy induced hypertension with odds ratio of 5.06 . Postpartum haemorrhage, incidence of wound infection,Intermediate care unit admission were statistically significant in exposed group .However there was no significant difference in maternal mortality among study group.APGAR score <7 in 5 minutes was 18%in exposed group and 5% in non exposed group (p=0.0039). Intrauterine fetal death was 6% in cases and none of respondants from control group had Intrauterine fetal death (p=0.0128). Frequency of low birth weight was 22% in exposed group and 9% in non exposed group(p=0.011). Conclusions: The burden of anemia in pregnant population is still high in eastern region of Nepal. Severe anemia in pregnancy carries significant risk to mother and fetus. Hence preventive measures need to be implemented at community level. Public awareness regarding pre-pregnancy hemoglobin status and importance of antenatal checkup relating with maternal and fetal adverse pregnancy outcome should be initiated. Journal of Nobel Medical College Vol. 2, No.1 Issue 3 Nov.-April 2013 Page 22-26 DOI: http://dx.doi.org/10.3126/jonmc.v2i1.7668

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The association of pregnancy-induced hypertension and neonatal hypospadias.

10.22541/au.161248631.13273255/v1 ◽

2021 ◽

Author(s):

Yi Wang ◽

Lin Wang ◽

Zeyong Yang ◽

Fang Chen ◽

Zhiwei Liu

Keyword(s):

Regression Analysis ◽

Birth Weight ◽

Gestational Age ◽

Occurrence Rate ◽

Multiple Birth ◽

Control Group ◽

Hypertensive Disorder ◽

Pregnancy Induced Hypertension ◽

Induced Hypertension ◽

In Pregnancy

Background: The prevalence of hypertensive disorder in pregnancy has been well-documented worldwide. In Chinese newborns, the risk of hypospadias in women with hypertension during pregnancy remains ambiguous. This study aimed to evaluate the relationship between hypertension in pregnancy and neonatal hypospadias based on a large sample of Chinese people. Methods: A retrospective cohort study was conducted at our hospital from 2015 to 2019. Mothers who delivered male infants with hypospadias or those without any malformations were enrolled. Factors such as hypertension, placenta previa, thyroid diseases, hepatitis B, obesity, multiple birth, amniotic fluid, gestational age, birth weight, and in vitro fertilization were collected to establish a regression analysis to assess risk factors for hypospadias. Results: In total, 41,490 mothers and 42,244 male infants were enrolled. The overall incidence of hypospadias was 0.23%. The occurrence rate of hypospadias in pregnancy-induced hypertension (PIH) group was higher than control group (0.944% vs. 0.186%, RR 5.08), whereas the occurrence rate in chronic hypertension group was 0%. Potential exposure factors were screened for hypospadias, and PIH, multiple birth, hyperthyroidism, preterm delivery, low birth weight, and small for gestational age (SGA) were found to have higher proportion of hypospadias in offspring. After adjustment for potential confounders in the multivariate regression analysis, PIH (OR: 2.437, 95% CI: 1.478–4.016, P<0.01), birth weight (OR: 0.852, 95% CI: 0.795–0.912, P<0.01), and SGA (OR: 3.282, 95% CI: 1.644–6.549, P<0.01) showed a significant relationship with hypospadias. Conclusion: Women with PIH had higher risks of hypospadias in offspring. Lower birth weight, SGA and hyperthyroidism were also statistically associated with hypospadias.

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Serum Lactate Dehydrogenase Level in Pregnancy Induced Hypertension and Fetomaternal Outcome

Nepal Medical College Journal ◽

10.3126/nmcj.v23i4.42207 ◽

2021 ◽

Vol 23 (4) ◽

pp. 275-280

Author(s):

Sarmila Prajapati ◽

Bekha Laxmi Manandhar ◽

Suvana Maskey ◽

Jyoti Sharma

Keyword(s):

Lactate Dehydrogenase ◽

University Teaching ◽

Serum Lactate Dehydrogenase ◽

Hypertensive Disorder ◽

Pregnancy Induced Hypertension ◽

Maternal Complications ◽

Elevated Liver Enzymes ◽

Induced Hypertension ◽

Fetal Complications ◽

In Pregnancy

Hypertensive disorders complicate 5-10% of all pregnancies and associated with potentially dangerous maternal and fetal complications. Studies have shown that pre-eclamptic patients with higher levels of lactate dehydrogenase (LDH) are at high risk of developing subsequent complications with poor maternal and fetal outcome. So with the aim to correlate serum LDH level in pregnancy induced hypertension (PIH) with fetomaternal outcome this hospital based observational descriptive study was done at Tribhuvan University Teaching Hospital (TUTH) for the duration of 1 year from 15th May, 2018 to 14th May, 2019. Women with PIH fulfilling inclusion criteria were enrolled in the study. Serum LDH level was measured and severity of PIH, maternal and perinatal outcome were studied according to the levels of LDH. Results were analyzed using SPSS 18. The incidence of hypertensive disorder in pregnancy was 4.74% in this study and total 180 cases were enrolled. The mean serum LDH level increased with increase in severity of PIH. Thirty two (17.7%) cases had maternal complications and hemolysis elevated liver enzymes and low platelet (HELLP) syndrome was most common complication. More than 2/3rd (62.5%) of cases with LDH level >800 IU/L had complications. The most common perinatal complication was intrauterine growth restriction (IUGR). The perinatal morbidity and mortality were significantly high in patients with PIH with LDH level >800 IU/l. As with the increase in serum LDH level increase in maternal and fetal complications was observed, LDH can be a useful biochemical marker that reflects the severity of PIH.

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Serum Uric Acid as a Prognostic Marker of Pregnancy induced Hypertension

Journal of SAFOG with DVD ◽

10.5005/jp-journals-10006-1194 ◽

2012 ◽

Vol 4 (3) ◽

pp. 130-133 ◽

Cited By ~ 1

Author(s):

Disha Sahijwani ◽

Ajesh Desai ◽

Hina Oza ◽

Vijay Kansara ◽

Pallavi Ninama ◽

...

Keyword(s):

Uric Acid ◽

Birth Weight ◽

Low Birth Weight ◽

Serum Uric Acid ◽

Prognostic Marker ◽

Gestational Hypertension ◽

Pregnancy Induced Hypertension ◽

Maternal Complications ◽

Induced Hypertension ◽

Laboratory Changes

ABSTRACT Objectives The purpose of the study is to determine the level of serum uric acid (s. uric acid) above which all complications occur, to analyze the maternal and fetal clinical and laboratory changes associated with elevated s. uric acid, and to determine whether s. uric acid can be used to predict maternal and fetal complications. Design A retrospective study of hospital records was done on 80 women of pregnancy induced hypertension including both gestational hypertension and preeclampsia from January 2011 to March 2012 at Civil Hospital, Ahmedabad. The women were divided in two groups: with s. uric acid > 6 mg/dl/ s. uric acid < 6 mg/dl. Results S. uric acid > 6 mg/dl was associated with maternal complications while s. uric acid > 5.5 mg/dl was associated with low birth weight babies. The mean creatinine and platelet count in two groups were significantly different at 5% level. Statistically significant elevation of s. uric acid was found in women of eclampsia. Conclusion S. uric acid > 6 mg/dl is associated with increased maternal complications specially eclampsia and higher incidence of low birth weight. Thus, women with pregnancy induced hypertension with s. uric acid > 6 mg/dl should be offered termination of pregnancy. How to cite this article Sahijwani D, Desai A, Oza H, Kansara V, Ninama P, Maheshwari K, Soni C, Padhiyar B. Serum Uric Acid as a Prognostic Marker of Pregnancy induced Hypertension. J South Asian Feder Obst Gynae 2012;4(3):130-133.

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EVALUATION OF TEMPERAMENT IN PREGNANCY INDUCED HYPERTENSION CASES

Indian Journal of Unani Medicine ◽

10.53390/ijum.v14i1.4 ◽

2021 ◽

Vol 14 (1) ◽

Author(s):

Rahnuma Sayed ◽

Naeela Ansari ◽

Shaikh Ejaz Parvez ◽

Farha Rizwan ◽

Rehan Safee ◽

...

Keyword(s):

Retrospective Study ◽

Maternal Death ◽

Pregnancy Induced Hypertension ◽

Exclusion Criteria ◽

Mortality And Morbidity ◽

The Third ◽

Tertiary Center ◽

The World ◽

Induced Hypertension ◽

In Pregnancy

Pregnancy induced hypertension (PIH) is a worldwide concern; 22 may is remembered every year as the world preeclampsia day. According to the WHO, PIH is one of the main causes of maternal, fetal and neonatal mortality and morbidity. In a retrospective study over the period 2000-2009 in a tertiary center in India, PIH was the third cause of maternal death. Material and Methods: One time observational hospital based study Patients as per inclusion and exclusion criteria were selected for the study. Consent of the patient recorded.

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