scholarly journals Liquid-based Cytology vs Conventional Cytology as a Screening Tool for Cervical Cancer in Postmenopausal Women

2017 ◽  
Vol 9 (2) ◽  
pp. 159-163 ◽  
Author(s):  
Uma Singh ◽  
Nisha Singh ◽  
Sabuhi Qureshi ◽  
Sakshi Foruin ◽  
Neha Negi ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Postmenopausal Women ◽  
Pap Smear ◽  
Screening Tool ◽  
Screening Method ◽  
Uttar Pradesh ◽  
Hormonal Changes ◽  
Conventional Cytology ◽  
Liquid Based Cytology ◽  
The Difference

ABSTRACT Aim To evaluate and compare the efficacy of liquid-based cytology (LBC) with conventional cytology (CS) as a screening tool for cervical cancer in postmenopausal women. Materials and methods This was an observational crosssectional study conducted over one year. Subjects were recruited from patients attending the outpatient department of the Department of Obstetrics and Gynecology, King George's Medical University, Lucknow, Uttar Pradesh, India. Pap smear and LBC were taken in all subjects. In cases with suspected lesions, the discrepancy between Pap smear and LBC and colposcopy was found. Results Pap smear reported 14.3% inadequate smears in women with postmenopausal changes and 5% inadequate smears in women without postmenopausal changes. In contrast, LBC reported no inadequate smear. This difference was statistically significant (p = 0.011). Cervical neoplasia was ruled out in 53.6% cases by Pap smear and 75.8% cases by LBC. The difference was statistically significant (p = 0.002). Conclusion Liquid-based cytology offers better results in detecting cervical pathology when compared with Pap smear. Liquid-based cytology could be better as a screening method, especially in postmenopausal women in which the screening is challenging due to menopause-induced anatomical and hormonal changes. Clinical significance Cervical cancer is the most common genital cancer among Indian women. Postmenopausal women are at higher risk for developing cervical cancer. Low estrogenic state poses a challenge for detection of cervical cancer by CS in postmenopausal women. We investigated LBC as a better cervical cancer screening tool in this age group. How to cite this article Qureshi S, Singh U, Foruin S, Negi N, Agarwal G, Singh N. Liquid-based Cytology vs Conventional Cytology as a Screening Tool for Cervical Cancer in Postmenopausal Women. J South Asian Feder Obst Gynae 2017;9(2):159-163.

scholarly journals How Liquid Based Cytology Surpasses Conventional Cytology - A Review Article

2021 ◽  
pp. 469-471
Author(s):  
Devikala Kumaresan
Keyword(s):  
Cervical Cancer ◽  
Pap Smear ◽  
Screening Tool ◽  
Precancerous Lesions ◽  
Invasive Cervical Cancer ◽  
Review Article ◽  
Cervical Smear ◽  
Cervical Lesions ◽  
Conventional Cytology ◽  
Liquid Based Cytology

Pap smear is the most widely used test for screening of cervical cancer and precancerous lesions. Liquid-based cytology is a cervical cancer screening technology that inspects cells by dissolving them in liquid and is used as a main screening tool for invasive cervical cancer. The purpose of this article is to demonstrate how fluid-based cytology has surpassed conventional cytology in the interpretation of cervical smear biopsy results in order to identify early cervical lesions in a more efficient and convenient manner, allowing for early diagnosis and treatment of cervical cancer patients and thus improving patient wellbeing.

scholarly journals Squamous lesions with glandular involvement: conventional cytology versus liquid-based cytology

2017 ◽  
Author(s):  
Telma Oliveira ◽  
Vera Azevedo ◽  
Rute Dominguez
Keyword(s):  
Cervical Cancer ◽  
Human Papillomavirus ◽  
European Country ◽  
Incidence Rate ◽  
Screening Method ◽  
Hpv Infection ◽  
Cervical Cytology ◽  
Western European Country ◽  
Conventional Cytology ◽  
Liquid Based Cytology

Portugal is the Western European country with the highest incidence rate of cervical cancer, being the Human Papillomavirus (HPV) infection its main cause. Cervical cytology is the most widely used screening method for the prevention and detection of cervical cancer, either by conventional means or by liquid basis. Conventional cytological preparations have more limitations than liquid-based preparations, however, when dealing with glandular lesions, both conventional and liquid-based cytology have some drawbacks. We report the case of a 31-year-old woman whose results from the screening cytology tests diverge from histological diagnosis. With this study we intend to highlight the limitations of conventional cytology in relation to the liquid-based cytology in the diagnostic of glandular lesions.

scholarly journals COMPARISON OF LIQUID-BASED CYTOLOGY AND CONVENTIONAL CYTOLOGY FOR EVALUATION OF CERVICAL PAP SMEARS

2019 ◽  
Vol 3 (1) ◽  
Author(s):  
Dr. Bipin Gandhi
Keyword(s):  
Cervical Cancer ◽  
Epithelial Cell ◽  
Pap Smear ◽  
Developed Countries ◽  
Low Grade ◽  
Squamous Intraepithelial Lesion ◽  
Conventional Cytology ◽  
Resource Setting ◽  
Intraepithelial Lesion ◽  
Liquid Based Cytology

INTRODUCTION: This high mortality rate from cervical cancer globally can be reduced by an approach that includes prevention, early diagnosis, effective screening and treatment programmes. There are currently vaccines that protect against common cancer-causing types of human papilloma virus and can significantly reduce the risk of cervical cancer. in low socioeconomic or developing countries where screening programmes are not available, diagnosing cervical cancer at an early stage and providing access to effective treatment can significantly improve the likelihood of survival. Liquid-based cytology (LBC) was introduced at around mid-1990s as an alternative technique to process the cervical samples. After that most of the developed countries has switched from conventional Pap smear to LBC. LBC has been proposed to be beneficial than Pap smear because of less number of unsatisfactory smears MATERIAL AND METHODS: This study comprises of 287 cervical samples from women visiting the Department of Obstetrics and Gynaecology over a period of 1 year.  Samples were taken and divided into two parts by split-sample technique.  Material was taken from the fornix, portio, and endocervix from all women. Slides for conventional cytology and LBC were stained according to the Pap method. LBC was considered representative if the slide contained >5000 epithelial cells. Endocervical cells were considered present if the slide contained ≥2 groups of glandular/metaplastic cells with ≥5 cells each or if the slide contained ≥10 dissociated glandular/metaplastic cells RESULTS: 287 patients were included in the study. Epithelial cell abnormality was observed in 10 cases in conventional smear while in LBC it was 11. In conventional smear pap report of Unsatisfactory, normal, atrophic, altered flora and candida was in 21,193, 21, 46 and 10 cases respectively. In LBC pap report Unsatisfactory, normal, atrophic, altered flora and candida was in 15,214, 22, 44 and 13 cases respectively. Epithelial cell abnormality was seen in 10 (3.5%) cases by both the methods. Of these 10 cases low grade squamous intraepithelial lesion was observed in 2 cases, High grade squamous intraepithelial lesion in one case, Squamous cell carcinoma in one case and atypical squamous cells of undetermined significance in 6 cases. CONCLUSION: There was a similar detection rate of epithelial abnormalities and infections in both the methods. US rate of CPS was 7.3% and 5.2% for LBC. Thus LBC can be a superior test as compared to conventional pap smear but has to reconsidered in the low-resource setting.

scholarly journals A comparison of liquid-based cytology and Pap smear as a screening method for cervical cancer

2007 ◽  
Author(s):  
Jie Zhu ◽  
Ingrid Norman ◽  
Kristina Elfgren ◽  
Vera Gaberi ◽  
Bjorn Hagmar ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Pap Smear ◽  
Screening Method ◽  
Liquid Based Cytology

scholarly journals Comparative study of conventional Pap smear and liquid based cytology as a screening method for cervical cancer

2021 ◽  
Vol 9 (8) ◽  
pp. 2439
Author(s):  
Bhagyalakshmi Atla ◽  
Uma Prasad ◽  
Venkata Satya Kartheek Botta ◽  
Uma Namballa ◽  
Lahari Pujari ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Epithelial Cell ◽  
Pap Smear ◽  
Screening Method ◽  
P Value ◽  
Pap Smears ◽  
Cervical Lesions ◽  
Malignant Lesions ◽  
Liquid Based Cytology

Background: Pap smear is the conventional screening procedure for cervical cancer. Liquid based cytology has been developed as a cost effective alternative as it has a short screening time, better morphology and clean background while also providing residual material to test for HPV DNA. Therefore this study is undertaken to know the role of Liquid-based cytology in evaluating pre-malignant and malignant lesions of cervix. Objectives of current study were to study the distribution of various cervical lesions on liquid-based cytology and compare them with conventional Pap smears. To know the role of liquid-based cytology in evaluating pre-malignant and malignant lesions of cervixMethods: This study included 200 women attending to gynaecology OPD and the samples were taken for both conventional cytology and liquid based cytology. The smears were studied in detail and were interpreted as per The Bethesda system 2014 of reporting pap smears and results are recorded and compared.Results: The commonest cervical lesions on pap smears by liquid-based cytology are NILM-reactive changes (N=92, 46%), NILM Candida infection is seen in 9 cases (4.5%) and trichomonas vaginalis infection in 5 cases (2.5%). Unsatisfactory smears on LBC is less when compared to conventional smears as the coefficient of correlation is significant with p value of 0.000422 (<0.05). The number of cases with a diagnosis of ASCUS is reported more in liquid-based cytology (9 cases) when compared to conventional Pap (8 cases). The number of cases with diagnosis of HSIL, SCC is reported more in liquid based cytology (7 cases) when compared to conventional Pap (4 cases). Epithelial cell abnormality were easily diagnosed on LBC smears with significant p value of 0.002414 (<0.05).Conclusions: Liquid-based cytology has advantages of fewer unsatisfactory smears and better detection of epithelial cell abnormalities when compared to conventional Pap smears. LBC is better for the screening of premalignant and malignant lesions of cervix even though it is costly.

A Comparison of Liquid-Based Cytology with Conventional Cytology in Cervical Cancer Screening

2012 ◽  
Vol 56 (4) ◽  
pp. 370-374 ◽  
Author(s):  
Setsu Akamatsu ◽  
Shoji Kodama ◽  
Yukari Himeji ◽  
Naomi Ikuta ◽  
Nikako Shimagaki
Keyword(s):  
Cervical Cancer ◽  
Cancer Screening ◽  
Cervical Cancer Screening ◽  
Conventional Cytology ◽  
Liquid Based Cytology

Comparison of Liquid-Based Cytology With Conventional Cytology for Detection of Cervical Cancer Precursors: A Randomized Controlled Trial

2010 ◽  
Vol 65 (3) ◽  
pp. 181-182
Author(s):  
Albertus G. Siebers ◽  
Paul J. J. M. Klinkhamer ◽  
Johanna M. M. Grefte ◽  
Leon F. A. G. Massuger ◽  
Judith E. M. Vedder ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Conventional Cytology ◽  
Liquid Based Cytology ◽  
Cancer Precursors
Sign in / Sign up

Export Citation Format

Share Document