scholarly journals Anxiety and depression are common in rheumatoid arthritis and correlate with poor quality of life in Indian patients

2021 ◽  
Vol 59 (6) ◽  
pp. 386-393
Author(s):  
Gurmeet Singh ◽  
Nikhil Mahajan ◽  
Sameer Abrol ◽  
Abhinav Raina
Keyword(s):  
Quality Of Life ◽  
Rheumatoid Arthritis ◽  
Poor Quality ◽  
Anxiety And Depression ◽  
Indian Patients

scholarly journals POS1455-HPR RELATIONSHIP BETWEEN PSYCHOLOGICAL FACTORS AND MEASURES OF RHEUMATOID ARTHRITIS ACTIVITY

2021 ◽  
Vol 80 (Suppl 1) ◽  
pp. 1011.2-1011
Author(s):  
Y. Olyunin ◽  
V. Rybakova ◽  
E. Likhacheva ◽  
E. Nasonov
Keyword(s):  
Quality Of Life ◽  
Rheumatoid Arthritis ◽  
Psychological Factors ◽  
Global Assessment ◽  
Activity Level ◽  
Anxiety And Depression ◽  
Tender Joint Count ◽  
Sf 36 ◽  
Patient Reported

Background:The patient-reported outcomes are important components of quantitative methods of rheumatoid arthritis (RA) activity assessment which are used to choose the appropriate drug therapy. The value of these parameters can be significantly affected not only by the inflammatory process, but also by the psychological characteristics of the patient and, in particular, by hardiness [1].Objectives:To study the relationship between psychological factors and signs of RA activity.Methods:Patients with RA who met the EULAR/ACR 2010 criteria, and observed at the V. A. Nasonova Research Institute of Rheumatology were included. Clinical examination was performed including patient global assessment (PGA), physician global assessment (PhGA), pain measurement on a visual analog scale, tender joint count (TJC), swollen joint count (SJC). The functional status was determined by HAQ, the quality of life – by SF-36 EQ-5D, the nature of pain – by painDETECT, the presence of anxiety and depression – by HADS. Patients also completed Hardiness Survey questionnaire to assess hardiness (HDS) and 3 components of the HDS – commitment (CMT), control (CT) and challenge (CLN). Disease activity was evaluated with DAS28, CDAI, and RAPID3. All patients signed informed consent to participate in the study. Analysis of the data was performed using Spearman’s rank test, Fisher exact test, qui-square and t-tests.Results:85 patients with RA were included. There were 69 women and 16 men. Mean age was 56.7±13.1 years, disease duration – 7.6±2.7 years. 72 patients were positive for rheumatoid factor, 75 – for anti-cyclic citrullinated peptide antibody. CDAI showed high activity in 15, moderate – in 37, low – in 30, and remission in 3 patients, DAS 28 – in 10, 55, 12, and 8, and RAPID3 – in 24, 25, 15, and 21, respectively. 24 patients had subclinically or clinically expressed anxiety and 15 –subclinically or clinically expressed depression (≥8 according to HADS). In 31 patients, the painDETECT questionnaire revealed possible or probable neuropathic pain. Mean HDS was 84.8±21.7, CMT – 38.9±9.2, CT – 29.4±8.6, CLN – 17.3±7.1. These values were comparable with the corresponding population data for this age group. There was a significant inverse correlation between HDS and RA activity measures, including SJC, TJC, DAS28 (p<0.05), pain, PGA, PhGA, CDAI, RAPID3, and HAQ (p<0.01). In addition, HDS and all its components positively correlated with quality of life, assessed by SF-36 and EQ-5D (p<0.01). In patients with subclinically and clinically expressed anxiety and depression, HDS, CMT, and CT were significantly lower than in patients without anxiety and depression (p<0.01), while the values of CLN in these groups did not differ significantly.Conclusion:The results of the present study suggest that low HDS may be one of the significant factors determining RA activity level because it does not allow patients to adapt adequately to a stressful situation produced by the disease.References:[1]Maddi SR. Am Psychol. 2008 Sep;63(6):563-4.Disclosure of Interests:None declared

Quality of life of osteoporotic patients attending rheumatology rehabilitation in-patient units

2012 ◽  
Vol 153 (33) ◽  
pp. 1314-1319
Author(s):  
Julianna Rozália Sallai ◽  
Gábor Héjj ◽  
István †Ratkó ◽  
Aniella Hunka ◽  
Ilona Márkus ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Rheumatoid Arthritis ◽  
Low Back Pain ◽  
Back Pain ◽  
Chronic Low Back Pain ◽  
Poor Quality ◽  
Low Back ◽  
Life Data ◽  
Sf 36

There has been no report on demographic, social and quality of life data of osteoporotic patients attending rheumatology rehabilitation in-patient units in Hungary. Aim: The authors analyzed the data of osteoporotic patients treated in rheumatology rehabilitation departments as in-patients in four hospitals in Hungary. Methods: Demographic and social data were obtained by using a questionnaire developed by the authors, and quality of life was assessed with the use of the SF-36 questionnaire. The quality of life data of osteoporotic patients were compared to that obtained from patients with rheumatoid arthritis, osteoarthrosis and chronic low back pain who were treated in the same department at the same time. Results: Of the 253 patients who were asked to participate in the study, 211 patients filled out the questionnaires. 25.6% of the patients were male. 58% of the patients were younger than 60 years of age, and 40% of them were heavy physical workers earlier. More than 50% of the patients did not complete secondary school education, and only 6.7% of the patients had a per capita monthly income higher than 100 000 HUF. The quality of life of the osteoporotic patients assessed by SF-36 scored 34.7, which was significantly lower than that of the mean of the Hungarian population scoring 70–90. The SF-36 scores of osteoporotic patients were lower in all domains compared to the scores of patients with rheumatoid arthritis, osteoarthritis and low back pain, although the difference was significant only in the domain of physical activity. The affective role of patients with osteoporosis was significantly lower than those with rheumatoid arthritis and osteoarthritis. Conclusions: Osteoporotic patients attending in-patient rheumatology in-patient rehabilitation units in Hungary have poor quality of life comparable, even worse than that found in patients with rheumatoid arthritis, osteoarthritis and chronic low back pain. Orv. Hetil., 2012, 153, 1314–1319.

Low cognitive reserve is associated with chronic migraine with medication overuse and poor quality of life

Cephalalgia ◽  
2014 ◽  
Vol 35 (8) ◽  
pp. 683-691 ◽  
Author(s):  
Marian Gómez-Beldarrain ◽  
Ane Anton-Ladislao ◽  
Urko Aguirre-Larracoechea ◽  
Isabel Oroz ◽  
Juan Carlos García-Moncó
Keyword(s):  
Quality Of Life ◽  
Chronic Migraine ◽  
Cognitive Reserve ◽  
Medication Overuse ◽  
Univariate Analysis ◽  
Poor Quality ◽  
Anxiety And Depression ◽  
Cross Sectional ◽  
Sf 36

Objective The objective of this article is to test the hypothesis that cognitive reserve (CR) is related to migraine chronification, medication overuse and poor quality of life in migraineurs. Design/methods A cross-sectional study on patients with chronic migraine with medication overuse (CM-MOH), episodic migraine (EM), and controls, matched by sex, age and education, was carried out. CR was assessed by a specific questionnaire, and quality of life was measured by general and specific questionnaires (SF-36 and MSQoL). Migraine Disability Assessment Scale and Beck questionnaires for depression and anxiety were used. Medication dependence was evaluated by the medication-dependence questionnaire in headache (MDQ-H). Results Fifty-five individuals were enrolled: 18 CM-MOH patients (32.73%), 22 EM patients (40%) and 15 controls (27.27%). Fifty (90.91%) of them were females and aged 43.53 (7.54) years. Univariate analysis showed a significant association between the study group and CR, and all items of the SF-36, anxiety and depression questionnaires, MSQoL and MDQ-H. The lower CR and CM-MOH group were related to a worse quality of life, more anxiety and depression and the highest medication dependence scores. Multivariate analysis showed that higher CR scores were related to higher quality of life as measured by the physical and mental composite scores of the SF-36, and to lower anxiety (beta = −1.08, p = 0.001) and depression (beta = −0.56, p = 0.03) levels. Focusing on MSQoL, the increase in CR was predictive of a better quality of life (beta = 1.88, p < 0.0001). By all the models, the explained variance of the sample ranged from 39% (mental composite score) to 58% (MSQoL). Conclusions Low CR appears to be an independent factor associated with the deterioration of quality of life, the presence of anxiety and depression, and drug dependence and medication overuse in CM-MOH.

scholarly journals Fibromyalgia Is Common and Adversely Affects Pain and Fatigue Perception in North Indian Patients with Rheumatoid Arthritis

2009 ◽  
Vol 36 (11) ◽  
pp. 2443-2448 ◽  
Author(s):  
VARUN DHIR ◽  
ABLE LAWRENCE ◽  
AMITA AGGARWAL ◽  
RAMNATH MISRA
Keyword(s):  
Quality Of Life ◽  
Rheumatoid Arthritis ◽  
Disease Activity ◽  
Functional Disability ◽  
Health Assessment ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
The North ◽  
Indian Patients

Objectives.Fibromyalgia (FM) has been shown to be common in patients with rheumatoid arthritis (RA), but studies on Asian patients are lacking. It remains unclear whether FM has an adverse influence on pain, fatigue, quality of life, and mood in these patients, and what its relationship is with disease activity. We studied prevalence and effects of FM in North Indian patients with RA and associations of RA with disease activity.Methods.This cross-sectional study included 200 RA patients and an equal number of controls. Presence of FM was defined using the American College of Rheumatology 1990 criteria. Pain and fatigue scores were assessed using a 10 cm visual analog scale. Quality of life and presence of depression/anxiety were determined using validated questionnaires. Disease activity and functional disability in RA patients was assessed using the Disease Activity Score 28-3 and Health Assessment Questionnaire, respectively.Results.FM was present in 15% of patients with RA compared to 2.5% of controls in the North Indian population. RA patients with FM did not differ from those without FM in terms of age, gender, current disease-modifying agents, or steroid use. RA patients with FM had higher disease activity and worse functional disability. The number of tender and swollen joints was higher in patients with FM, but correlated poorly with each other. RA patients with FM had higher pain and fatigue scores but were not different in the quality of life or mood.Conclusion.FM is more common in North Indian patients with RA compared to controls. It adversely affects the pain and fatigue felt by RA patients. Disease activity and FM influence each other.

scholarly journals The Impact of Schizotypy on Quality of Life Among Adults with Autism Spectrum Disorder

2021 ◽  
Author(s):  
Albin Klang ◽  
Britta Westerberg ◽  
Mats B. Humble ◽  
Susanne Bejerot
Keyword(s):  
Quality Of Life ◽  
Autism Spectrum Disorder ◽  
Autistic Traits ◽  
Poor Quality ◽  
Autism Spectrum ◽  
Spectrum Disorder ◽  
Anxiety And Depression ◽  
Schizotypal Personality ◽  
The Impact

Abstract Background: Autism spectrum disorder (ASD) and schizotypal personality disorder can be difficult to distinguish. Deficits in social relationships and social interaction, present in both conditions, are known to impair quality of life. The aim of the present study was to investigate if schizotypal symptoms affect quality of life among adults diagnosed with autism spectrum disorder and to study the association between schizotypy and autistic traits among them. Methods: Participants diagnosed with autism spectrum disorder (n=110) completed questionnaires exploring schizotypy (Schizotypal Personality Questionnaire – Brief Revised (SPQ-BR)), autistic traits (The Ritvo Autism, Asperger Diagnostic Scale-Revised Screen 14 items), anxiety and depression (The Hospital Anxiety and Depression scale) and quality of life (Brunnsviken Brief Quality of Life Scale and the European quality of life index version 5D). Results: Schizotypy was found to be associated with anxiety, depressive and autistic symptoms, and poor quality of life. Although schizotypy was a predictor for impaired quality of life, this relationship was mediated by symptoms of anxiety and depression, plausibly inherent to autism. Autistic traits were positively associated with all higher order constructs of the SPQ-BR, i.e. positive and negative schizotypy, disorganization and social anxiety, as well as with poor quality of life. Conclusions: There is considerable overlap between schizotypy and autism that needs to be considered in research. Prominent schizotypal traits in people with ASD may constitute an endophenotype coinciding with a particularly poor quality of life.

scholarly journals Anxiety, depression and quality of life in mothers of intellectually disabled children

2018 ◽  
Vol 6 (2) ◽  
pp. 28-35
Author(s):  
N Sapkota ◽  
A K Pandey ◽  
BK Deo ◽  
MK Shrivastava
Keyword(s):  
Quality Of Life ◽  
Intellectual Disability ◽  
Poor Quality ◽  
Anxiety And Depression ◽  
Disabled Children ◽  
Intellectually Disabled ◽  
Icd 10 ◽  
Anxiety Depression ◽  
The Relationship

Introduction: Studies have shown that there is an association between Anxiety, Depression in mothers of children having Intellectual disability with poor quality of life (QOL) in mothers of such children. This study was carried with the objectives to describe the clinico-socio-demographic profile of mothers of intellectually disabled children and to investigate the relationship among anxiety and depression with quality of life in mothers with intellectually disabled children.Material And Method: Mothers (N=31), whose children's IQ score was below 70, were enrolled in to the study with their informed consent. Depression and Anxiety disorders were diagnosed as per ICD 10. Severity of depression was measured with BDI and Anxiety symptoms with STAI. WHOQOL-BREF was used to assess Quality of life. The relationship among anxiety, depression and QOL were analysed using diagonal matrix, ANOVA and Pearson correlation test.Results: The mean age of participants was 50.23 (S.D= 6.11), BDI score was 13.65(S.D= 11.301), STAI score was 53.90 (SD= 15.821), WHOQOL- BREF in all four domains was 290.90 (S.D=49.42). There was significant correlation between BDI and STAI (P=0.01, r:0.651 ) and the three domains of WHOQOL- BREF(P=0.01, r:0.821, 0.843, 0.635 respectively) scale except Environment domain. Among the participants, 48.4% (ICD 10) had depression of varying degree along with 54.8% depression as per BDI cut off score. Anxiety disorder was seen in 22.6% as per ICD 10 but as per STAI it was 53.90(SD=15.821) which was statistically significant (p:0.01, r: -0.507). Depression when compared with no diagnosis persons has poor quality of life in WHOQOL-BREF physical domain (p:0.002) but with compared to Anxiety or both it was not statistically significant.Conclusion: The findings of this study revealed that mothers of children having Intellectual disability have high level of Anxiety and Depression which indeed had impact in quality of life. J Psychiatrists’ Association of Nepal Vol. 6, No. 2, 2017 Page: 28-35

Predictors of quality of life, symptoms of anxiety, and depression in Latino patients with cervical cancer.

2018 ◽  
Vol 36 (34_suppl) ◽  
pp. 171-171
Author(s):  
Oscar Galindo Vazquez ◽  
Mayra CU Menes ◽  
David Ortiz ◽  
Abelardo Meneses-Garcia ◽  
Jose Luis Aguilar ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cervical Cancer ◽  
Depression Scale ◽  
Psychosocial Care ◽  
Poor Quality ◽  
Anxiety And Depression ◽  
Chi Square ◽  
European Organization ◽  
Exact Test

171 Background: Cervical cancer is considered one of the most frequent cancers among women and with the greatest causes of death in the world. In Mexico it is considered the second cause of death. Objective: The identify predictors of quality-of-life, symptomatology of anxiety and depression in patients with cervical cancer. Methods: 192 patients with cervical cancer aged between 44 and 60 years were included, through interview and consultation of the clinical file, information on sociodemographic and clinical variables were obtained. Instrument: European Organization Scale for Cancer Research and Treatment and Quality of Life (EORTC QLC-C30) and Hospital Anxiety and Depression Scale (HADS). Statistical analysis: Chi square or Fisher´s exact test. The association of the variables was evaluated by logistic regression analysis. Results: 48% had poor quality of life, 24% with depression, and 29% with anxiety.The predictors of a low quality of life are: presenting one or more comorbidities, family history with cancer, presenting anxious, and depressive symptoms Conclusions: Psychological assumptions are predictors of variables such as quality of life, in a population with cervical cancer, in Mexico this group of patients have low educational and economic levels. Psychosocial care programs are required in this group of Latina women.

Quality of Life in Indian Patients with Rheumatoid Arthritis

2005 ◽  
Vol 14 (8) ◽  
pp. 1953-1958 ◽  
Author(s):  
Gurdesh S. Bedi ◽  
Nikhil Gupta ◽  
Rohini Handa ◽  
Hemraj Pal ◽  
R. M. Pandey
Keyword(s):  
Quality Of Life ◽  
Rheumatoid Arthritis ◽  
Indian Patients

Patient-reported outcomes are independent predictors of one-year mortality and cardiac events across cardiac diagnoses: Findings from the national DenHeart survey

2018 ◽  
Vol 26 (6) ◽  
pp. 624-637 ◽  
Author(s):  
Selina K Berg ◽  
Charlotte B Thorup ◽  
Britt Borregaard ◽  
Anne V Christensen ◽  
Lars Thrysoee ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Hospital Discharge ◽  
Patient Reported Outcomes ◽  
Severe Symptom ◽  
Poor Quality ◽  
Anxiety And Depression ◽  
Cardiac Events ◽  
Patient Reported ◽  
One Year

Aims Patient-reported quality of life and anxiety/depression scores provide important prognostic information independently of traditional clinical data. The aims of this study were to describe: (a) mortality and cardiac events one year after hospital discharge across cardiac diagnoses; (b) patient-reported outcomes at hospital discharge as a predictor of mortality and cardiac events. Design A cross-sectional survey with register follow-up. Methods Participants: All patients discharged from April 2013 to April 2014 from five national heart centres in Denmark. Main outcomes Patient-reported outcomes: anxiety and depression (Hospital Anxiety and Depression Scale); perceived health (Short Form-12); quality of life (HeartQoL and EQ-5D); symptom burden (Edmonton Symptom Assessment Scale). Register data: mortality and cardiac events within one year following discharge. Results There were 471 deaths among the 16,689 respondents in the first year after discharge. Across diagnostic groups, patients reporting symptoms of anxiety had a two-fold greater mortality risk when adjusted for age, sex, marital status, educational level, comorbidity, smoking, body mass index and alcohol intake (hazard ratio (HR) 1.92, 95% confidence interval (CI) 1.52–2.42). Similar increased mortality risks were found for patients reporting symptoms of depression (HR 2.29, 95% CI 1.81–2.90), poor quality of life (HR 0.46, 95% CI 0.39–0.54) and severe symptom distress (HR 2.47, 95% CI 1.92–3.19). Cardiac events were predicted by poor quality of life (HR 0.71, 95% CI 0.65–0.77) and severe symptom distress (HR 1.58, 95% CI 1.35–1.85). Conclusions Patient-reported mental and physical health outcomes are independent predictors of one-year mortality and cardiac events across cardiac diagnoses.

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