scholarly journals TREATMENT OF VERTIGO- WITH & WITHOUT ANXIOLYTIC DRUG (ALPRAZOLAM 0.25MG)

2021 ◽  
Vol 71 (Suppl-3) ◽  
pp. S445-47
Author(s):  
Muhammad Waqas Ayub ◽  
Syed Muhammad Asad Shabbir Bukhari ◽  
Mohsin Raza ◽  
Asma Waqas ◽  
Beenish Hassan Khan ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Treatment Outcome ◽  
Comparative Study ◽  
Conventional Treatment ◽  
Post Treatment ◽  
Beck Anxiety Inventory ◽  
Military Hospital ◽  
Trial Group ◽  
Group A ◽  
Group B

Objective: To compare the effect of using the tablet Alprazolam 0.25mg in the treatment outcome of vertigo related anxiety by beck anxiety inventory. Study Design: Comparative study. Place and Duration of Study: Combined Military Hospital Okara Cantt, Sep 2018 to Jun 2020. Methodology: A total of 384 patients were included in the study. They were randomly assigned to group A and B by randomized clinical trial. Group A was given tablet alprazolam 0.25 mg along with the conventional treatment of vertigo and group B was given the treatment of vertigo only and no anxiolytic was added. Their pre & post treatment (after 2 weeks) anxiety level using Beck anxiety inventory was scored. Results: There was a significant improvement in group A patient’s vertigo effects after treatment with alprazolam. Also, it was observed that group A patients responded significant improvement in anxiety score as compared to Group B patients 02 weeks post treatment. Conclusion: Antianxiety treatment should be added in all cases with the conventional treatment of vertigo to reduce the vertigo associated anxiety of the patients.

scholarly journals A “A COMPARATIVE STUDY OF ASITAKADI CHURNA AND ALAMBUSADI CHUNA IN THE MANAGEMENT OF AMAVATA”

2021 ◽  
Vol 5 (02) ◽  
Author(s):  
Dr.PRIYANKA KANDIKATTIWAR
Keyword(s):  
Clinical Trial ◽  
Comparative Study ◽  
Signs And Symptoms ◽  
Trial Group ◽  
Group A ◽  
Independent Life ◽  
Group B

ABSTRACT: - INTRODUCTION: - Amavata is one of the challenging diseases for the physicians due to its chronic nature, difficulty, complications. Amavata is the prime disease which makes the person unfit for an independent life. In this study, Asitakadi Churna  and Alambusadi chuna are considered, as both the drugs possess Vata-Kaphahara and Amapachak properties. Here an attempt is made to compare the efficacy of Asitakadi Churna  and Alambusadi chuna in Amavata with the title “A Comparative study of Asitakadi Churna  and Alambusadi chuna in the management of Amavata” AIM & OBJECTIVE: - To compare effect of Alabushadi churna  and Asitakadi churna in Amavata. MATERIALS AND METHODS - The patients were selected from the OPD and IPD of concern institution. 60 patients of Amavata were randomly selected and divided into two groups of 30 patients each, and subjected to clinical trial. Group- A patients were treated with Asitakadi Churna  and Group-B patients were treated with Alambusadi chuna. The signs and symptoms were recorded on the preformed designed for the study and assessment was done on subjective and objective criteria and results were analyzed statistically. RESULT – In the present study, it is concluded that both Group A and Group B showed significance in decreasing shool, Shoth, gourava, and jadya. Asitakadi Churna  is equally effective as Alambusadi chuna in on  Amavata. CONCLUSION – The treatments were found to be statistically significant in reducing the signs and symptoms of the disease.

scholarly journals THE EFFECT OF INTRAVENOUS MAGNESIUM SULFATE ON CHILDREN ADMITTED WITH ACUTE BRONCHIOLITIS IN A TERTIARY CARE HOSPITAL

2021 ◽  
Vol 71 (6) ◽  
pp. 2148-51
Author(s):  
Andaleeb Ara ◽  
Farooq Ikram ◽  
Hidayat Ullah ◽  
Shakila Asmat ◽  
Nadia Tareen
Keyword(s):  
Magnesium Sulfate ◽  
Conventional Treatment ◽  
Clinical Severity ◽  
Military Hospital ◽  
Care Hospital ◽  
Acute Bronchiolitis ◽  
Intravenous Magnesium ◽  
Significant Difference ◽  
Group A ◽  
Group B

Objective: To assess the efficacy of using intravenous Magnesium Sulfate along with the conventional treatment in the management of acute bronchiolitis Study Design: Quasi-experimental study. Place and Duration of Study: Pediatrics department in Sandeman Provincial Hospital, Quetta, from Jan to Jul 2019. Methodology: The study was approved by institutional ethical committee of Combined Military Hospital, Peshawar. Children, 2 months to 2 years of age, with acute bronchiolitis having clinical severity score of ≥5, presenting to the OPD and emergency department were enrolled in the study after getting informed consent from the guardian. They were randomly assigned group A receiving intravenous Magnesium Sulfate and group B receiving placebo along with the conventional treatment for both. Data was analysed with SPSS-21. Results: Total 108 patients were included in the study with 54 (50%) in group A and 54 (50%) in group B. Mean age in the study was 12.02 ± 6.421 months. Mean age in group A and B was 11.17 ± 6.40 and 12.87 ± 6.38 months respectively. Out of 108 patients 50 (46.3%) were males while 58 (53.7%) were females. There was statistically significant difference in the efficacy of treatment between two groups with values being 48 (88.9%) and 37 (68.5%) for Magnesium Sulfate and control groups respectively (p=0.01). Conclusion: From a clinical point of view, intravenous Magnesium Sulfate combined with conventional treatment is more effective than conventional treatment alone in the management of acute bronchiolitis.

scholarly journals COMPARATIVE STUDY OF EFFICACY OF SHATAVARI GHRUTA ANJANA AND ERANDA TAILA ANJANA IN THE MANAGEMENT OF VISUAL DISPLAY TERMINAL SYNDROME

2021 ◽  
Vol 9 (9) ◽  
pp. 1958-1965
Author(s):  
Vijay Dubey ◽  
S.S. Salvi
Keyword(s):  
Clinical Trial ◽  
Comparative Study ◽  
Statistical Methods ◽  
Clinical Data ◽  
Visual Display ◽  
Exclusion Criteria ◽  
Visual Display Terminal ◽  
Group A ◽  
Group B ◽  
Ethical Clearance

This study was conducted to evaluate the efficacy of Shatavari ghutra Anjana and Eranda taila anjana in the management of the visual display syndrome. For this work patients attending the netraroga (oph- thalmology) OPD at the hospital attached to Tilak Ayurveda Mahavidyalaya, Pune (Maharashtra) was selected based on the inclusion and exclusion criteria of the study. Ethical clearance was accredited by the institutional ethical committee of the institute and written consent from all the selected patients was taken before the treatment. The selected patients were randomly divided into two groups. Group A was given Shatavari ghruta anjana in each eye one time a day for one month and group B was given Eranda taila anjana in each eye one time a day for one month. The clinical data collected and compiled from this clinical trial was sorted out processed by implying various statistical methods and it was found that Group A showed comparatively better results in redness of eyes and eye irritation. Keywords: Shatavari ghruta anjana, Eranda taila anjana, visual display syndrome.

scholarly journals Comparative study of standardized apamarga ksharsutra and traditional ksharsutra in the management of bhagandara w. s. r. fistula in ano.

2018 ◽  
Vol 6 (5th) ◽  
Author(s):  
Bharat Madhukar Rokade ◽  
Umesh Vaidya
Keyword(s):  
Clinical Trial ◽  
Statistical Analysis ◽  
Comparative Study ◽  
Fistulous Tract ◽  
Medical Sciences ◽  
Fistula In Ano ◽  
The World ◽  
Average Unit ◽  
Group A ◽  
Group B

Fistula in Ano is condition which has been recognized as difficult surgical diseases in all ancient & modern medical sciences of the world. In Ayurvedic text it is described as Bhagandara. Ksharsutra is a unique and an established procedure for the management of Bhagandara in Ayurveda. It has brought upheaval in the Indian system of Surgery. The aim of the study was to compare standardized or traditional ksharsutra therapy in the management of fistula in Ano. Materials & methods- The study was randomized clinical trial carried out at anorectal unit of Shalya tantra department of College of Ayurved, Bharati Vidyapeeth Deemed to be University, Pune. The technique involved   passing a medicated seton(Ksharsutra) through fistulous tract. 40 patients with fistula in Ano were selected and divided into two groups of twenty patients each. Group A was treated with standardized ksharsutra and Group B with the traditional ksharsutra. Result- The healing occurred in all patients treated either with standardized or traditional ksharsutra. The average unit cutting time was 5.8 for standardized ksharsutra and 6.7with traditional ksharsutra. Statistical analysis was done.

scholarly journals Comparative prospective randomized open label trial of synbiotic (bifilac) as an add on therapy with standard treatment in patients with aphthous ulcer

2018 ◽  
Vol 7 (5) ◽  
pp. 878
Author(s):  
Sasikala G. ◽  
Malar Sivaraman ◽  
Trayambak Dutta ◽  
Dhanasekar K. R.
Keyword(s):  
Conventional Treatment ◽  
Standard Treatment ◽  
Aphthous Ulcer ◽  
Control Group ◽  
Trial Group ◽  
Open Label ◽  
Aphthous Ulcers ◽  
Group A ◽  
Mean Size ◽  
Group B

Background: To trial the safety, efficacy and rapidity of response to a lozenges containing synbiotic in patients with minor aphthous ulcer.Methods: A total of 60 patients were enrolled for the trial after obtaining IEC approval and randomly allocated into two groups. Control “Group A” was administered with conventional treatment i.e., zytee and B complex for 2 weeks and trial “Group B” was administered with Bifilac along with conventional treatment for 2 weeks. The results of this trial were analyzed both subjectively and objectively.Results: Comparing with control group, where standard treatment was used with analgesics and B-complex, the trial group showed a quick relief of pain and helped in reducing mean size of ulcer.Conclusions: This trial was done with synbiotic lozenges in minor aphthous ulcers and it proved to be better alternative for them. Moreover, synbiotics have no adverse effects.

scholarly journals Comparative Study of Topical Oxiconazole Cream (1%) Versus Ketoconazole Cream (2%) in the Treatment of Inguinocrural Dermatophytoses

2017 ◽  
Vol 28 (2) ◽  
pp. 57-61
Author(s):  
Farzana Afroz ◽  
Md Shahidullah ◽  
Mohd Nurul Alam ◽  
Humaira Afreen ◽  
Tahmina Sultana ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Comparative Study ◽  
Once Daily ◽  
Male And Female ◽  
Medical College ◽  
Group A ◽  
The Mean ◽  
The Difference ◽  
Group B

A clinical trial was carried out for the duration of six months from September' 2012 to February' 2013 in the Department of Dermatology and Venereology, Shaheed Monsur Ali Medical College, Uttara Dhaka and patients attending private clinical chamber. To evaluate the effectiveness of oxiconazole cream in comparison to the ketoconazole cream for the treatment of inguinocrural dermatophytoses.A total number of 60 patients with inguinocrural dermatophytoses were included in the study of which 30 patients were treated with oxiconazole (Group A) and the rest 30 patients were treated with ketoconazole (Group B)once daily for 21 days and weekly the outcome of lesions were clinically evaluated and recorded.In group A, male and female were 17 (56.7%) cases and 13 (43.3%) cases respectively. In group B, male and female were 16 (53.3%) cases and 14 (46.7%) cases respectively.The mean age with SD in group A and group B were 28.93 ± 8.29 years and 31.36 ± 8.36 years respectively. The mean scoring with SD in group A and group B were 6.26 ± 2.22 minutes and 6.53 ± 1.81 minutes respectively at the time of observation and 4.23 ± 1.50 minutes and 5.13 ± 1.45 minutes respectively after 1 week and 2.00 ± 1.22 minutes and 3.25 ± 1.07 minutes respectively after 2 weeks. The difference between the mean score of the two group is significant (p=0.006). The mean scoring with SD in group A and group B were 0.00 ± 0.00 minutes and 1.75 ± 0.95 respectively after 3 weeks.Sotopical treatment oxiconazole has revealed itself to be as efficient as ketoconazole and it seems more effective and better tolerated than ketoconazole.Medicine Today 2016 Vol.28(2): 57-61

scholarly journals COMPARISON OF MONTHLY PULSE OF ORAL AZITHROMYCIN WITH DAILY DOXYCYCLINE IN THE TREATMENT OF MODERATE ACNE VULGARIS

2021 ◽  
Vol 71 (Suppl-1) ◽  
pp. S268-72
Author(s):  
Muhammad Mudassir ◽  
Ali Amar ◽  
Naeem Raza ◽  
Ayesha Khokhar ◽  
Adeel Siddiqui ◽  
...  
Keyword(s):  
Acne Vulgaris ◽  
Severity Index ◽  
Post Treatment ◽  
Military Hospital ◽  
Dermatology Department ◽  
Oral Doxycycline ◽  
Group A ◽  
Pre Treatment ◽  
Group B ◽  
Oral Azithromycin

Objective: To compare oral Azithromycin with oral Doxycycline in treatment of moderate Acne Vulgaris. Study design: Randomized control trial Place and duration of the study: Dermatology Department , Pak Emirates Military Hospital, Rawalpindi from 1st August 2017 till 31st January 2018. Materials and methods: A total of 92 patients with moderate Acne were selected from Dermatology outpatient department (OPD) Pak Emirates Military Hospital Rawalpindi, after written informed consent. Patients were randomly allocated to one of the two treatment groups: Group A and Group B by lottery method. Patients in group A were given oral Azithromycin 500 mg daily for four consecutive days each month for 03 months and patients in group B were given oral Doxycycline 100 mg daily for 03 months. Patients were reviewed monthly for 03 months and Acne Severity Index (ASI) was recorded at baseline, at one month and three months. The primary outcome measured was more than 50% decrease from baseline in ASI within 3 months of treatment, using Global Acne Grading System (GAGS). Results: Mean age of patients in group A was 21.80 + 4.64 years whereas mean age of patients in group B was 21.61 + 4.48 years. In group A mean pre-treatment ASI was 24.83 + 3.15 and mean post-treatment ASI was 10.15 + 1.7. In group B mean pre-treatment ASI was 25.30 ± 2.96 and mean post-treatment ASI was 9.86 + 1.58. Conclusion: Azithromycin is comparable to Doxycycline in terms of mean change in ASI, in the treatment of moderate Acne Vulgaris.

COMPARATIVE STUDY IN BETWEEN INTRALESIONAL VITAMIN D3 AND INTRALESIONAL BLEOMYCIN IN THE TREATMENT OF CUTANEOUS VERRUCAE

2020 ◽  
Vol 4 (8) ◽  
Author(s):  
Shrikant . ◽  
R.D. Mehta ◽  
B.C. Ghiya
Keyword(s):  
Partial Response ◽  
Comparative Study ◽  
Recurrence Rate ◽  
Vitamin D3 ◽  
Complete Response ◽  
Recurrence Rates ◽  
Additional Advantage ◽  
Cost Effective Treatment ◽  
Group A ◽  
Group B

Background: Verruca is one of the common dermatopathologies which has multiple therapeutic options but with variable success rates, refractory cases and high recurrence rates. Nowadays, treatment with intralesional injections has gained recognition due to its effectiveness in clearing verrucae. These act by stimulating the cell-mediated immunity. Out of scores of options available for intralesional therapeutics, Vitamin D3 appears to be more promising but least evaluated. Therefore, we planned to evaluate the efficacy of intralesional Vitamin D3 in various types of cutaneous verrucae. Simultaneously the results were compared with intralesional bleomycin, also. Methods: A total of 200 patients of cutaneous verrucae with varying size and duration were included in the experimental randomized comparative study. We divided them into two groups. Group A, comprising of 100 patients, received 0.2-0.5 ml intralesional Vitamin D3 (600,000 IU, 15mg/ml) and Group B, also of hundred subjects, received intralesional Bleomycin (1 mg/ml) into the base of verrucae. A maximum of 5 verrucae were injected per session at 3 weeks interval until resolution or for a maximum of 4 sessions. Patients were followed up for 6 months after the last injection to assess the clearance status and detect any recurrence. Results: In Group A (Vitamin D3), 'Complete response', 'Partial response' and 'No response' were observed in 85.07%, 6.74% and 8.17% respectively after 4 sessions. Recurrence rate was 0.81% after 6 months. In Group B (Bleomycin), 'Complete response', 'Partial response' and 'No response' were found in 77.99%, 10.47% and 11.53% in the series. Recurrence rate was 1.71%, comparatively higher in group B. Conclusion: The efficacy of intralesional Vitamin D3 was found significantly higher as compared to intralesional Bleomycin in the treatment of cutaneous verrucae with less recurrence rates. Vitamin D3 has an additional advantage of cost-effective treatment over Bleomycin. We purpose its use, as a primary mode of treatment in various types of cutaneous verrucae. Keywords: Bleomycin, Vitamin D3, Verrucae.

Comparative Study Between Clean Intermittent Self-Catheterization (Cisc) and Continuous Indwelling Catheterization (Cidc) in Relieving Acute Refractory Retention of Urine Due to Benign Enlargement of Prostate (Bep)

2020 ◽  
Vol 21 (2) ◽  
pp. 105-110
Author(s):  
Md Shawkat Alam ◽  
Sudip Das Gupta ◽  
Hadi Zia Uddin Ahmed ◽  
Md Saruar Alam ◽  
Sharif Muhammod Wasimuddin
Keyword(s):  
Comparative Study ◽  
Acute Urinary Retention ◽  
Bladder Capacity ◽  
Inclusion Criteria ◽  
College Hospital ◽  
Medical College ◽  
High Incidence ◽  
Group A ◽  
Group B ◽  
Better Than

Objective: To compare the clean intermittent self-catheterization (CISC) with continuous indwelling catheterization (CIDC) in relieving acute urinary retention (AUR) due to benign enlargement of prostate (BEP). Materials and Methods :A total 60 patients attending in urology department of Dhaka Medical college hospital were included according to inclusion criteria ,Patients were randomized by lottery into two groups namely group –A and group –B for CISC and IDC drainage respectively . Thus total 60 patients 30 in each group completed study. Results : Most men can safely be managed as out-patients after AUR due to BPH. The degree of mucosal congestion and inflammation within the bladder was found to be lower in those using CISC and the bladder capacity in these patients was also found higher.Patients with an IDC had a high incidence of UTIs then that of patients with CISC. During the period of catheterization the incidence of UTI was 43.3% in group B in comparison to 40% in group A; before TURP 36% in group B in comparison to 10% incidence in group A.According to patient’s opinion CISC is better than IDC in the management of AUR. Experiencing bladder spasm, reporting blood in urine, management difficulties, incidence and severity of pain were less in CISC group, and the method of CISC was well accepted by patients as well as their family members. Conclusion: From the current study it may be suggested that CISC is better technique for management of AUR patient due to BPH than IDC. It can also be very helpful when surgery must be delayed or avoided due to any reasons in this group of patients. Bangladesh Journal of Urology, Vol. 21, No. 2, July 2018 p.105-110

scholarly journals A comparative study between the effect of verapamil versus nalbuphine as an adjuvant in supraclavicular brachial plexus block

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Mohammed Ibrahim Khamis ◽  
Ahmed Saeed Mohamed ◽  
Hesham Mohamed El Azazy ◽  
Hala Salah El Ozairy ◽  
Mohamed Moien Mohamed
Keyword(s):  
Comparative Study ◽  
Brachial Plexus ◽  
Normal Saline ◽  
Motor Block ◽  
Brachial Plexus Block ◽  
Sensory Block ◽  
Motor Blockade ◽  
Group A ◽  
Group B ◽  
Plexus Block

Abstract Background Brachial plexus block has substituted general anesthesia in the majority of patients planned for upper limb surgeries as it avoids the undesired effects of the medications used in general anesthesia as well as the stress response associated with airway manipulation. Opioid agonist–antagonists such as nalbuphine are used as adjuvant to improve the anesthetic properties of bupivacaine. Verapamil has an additive effect in brachial plexus blockade in the form of decreasing the consumption of analgesics in the postoperative period with reducing onset time and extending the duration of motor and sensory blockade. The aim of this study is to investigate the adjuvant effect of verapamil versus nalbuphine to 0.5% bupivacaine in brachial plexus block as regards onset, duration of sensory and motor blockade and postoperative analgesic augmentation. The study is randomized, prospective, double-blinded, comparative study where 90 patients subjected to arm, forearm and hand surgeries were randomized into three groups, group A received 30 ml of plain bupivacaine 0.5% plus 2 ml of normal saline, group B received 30 ml of bupivacaine 0.5% plus 2 ml verapamil equivalent to 5 mg, group C received 30 ml of bupivacaine 0.5% plus 10 mg of nalbuphine diluted in 2 ml of normal saline. Results Results of this study showed that group C and group B sensory block time onset was 7.25 ± 1.5 vs. 10.92 ± 3.84 min, P < 0.001 and was shorter than that in group A (13.2 ± 2.66 min). In addition, the motor block onset was (11.10 ± 1.24 vs. 13.50 ± 3.77 min, P < 0.001) shorter than group A (17.16 ± 1.30 min). In group C and group B, sensory block duration was 396 ± 32.17 vs. 355.83 ± 18.48 min, P < 0.001, respectively and was longer than that in group A (321.13 ± 25.08 min). Also, there was prolonged motor block duration in group C and group B recording (338.92 ± 25.2 vs. 302.93 ± 15.24 min, P < 0.001) and was longer than that in group A (280.70 ± 32.35 min). Time of demand of rescue analgesia dose was significantly long in group C and group B (449.53 ± 52.45 vs. 418.13 ± 41.12 min, P < 0.001) and was longer than group A (361.31 ± 21.42 min). Both verapamil and nalbuphine have additive effect to bupivacaine improving the all anesthetic parameters of the block. Conclusion Both drugs produce favorable enhancement of time onset and effective prolongation of duration of sensory and motor blockade and extend the period of postoperative analgesia with superiority to nalbuphine over verapamil.

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