scholarly journals MICRO NEEDLING VERSUS CARBON DIOXIDE FRACTIONAL LASER IN MANAGEMENT OF ACNE SCARS

2021 ◽  
Vol 71 (6) ◽  
pp. 2095-98
Author(s):  
Shanza Obaid ◽  
Nadia Iftikhar ◽  
Asher Mashhood ◽  
Ayesha Khokhar ◽  
Zarnab Zainab ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Side Effects ◽  
Adverse Effects ◽  
Laser Treatment ◽  
Military Hospital ◽  
P Value ◽  
Fractional Laser ◽  
Acne Scars ◽  
Number Of Patients ◽  
Laser Group

Objective: To compare the effectiveness of carbon dioxide fractional laser with micro needling in acne scarring. Study Design: Quasi experimental study. Place and Duration of Study: Department of Dermatology, Pak Emirates Military Hospital Rawalpindi, from Jun 2019 to Mar 2020. Methodology: Overall 40 patients with acne scars assessed by consultant dermatologist were made part of study. The patients were divided into two treatment groups through lottery method. Group A, was managed by micro needling technique, while Group B was managed by carbon dioxide fractional laser, each to be done monthly for a total of three sessions. The response was measured by the dermatologist and patients in both the groups. The side effects were also compared in both the groups. Results: Out of 40 patients with acne scars included in study, 17 (42.5%) underwent micro-needling while 23 (57.5%) underwent carbon dioxide fractional laser treatment after randomization. Thirty (75%) patients were female while 10 (25%) were male. The patients with acne scars responded better in carbon dioxide fractional laser group as compared to micro needling in opinion of dermatologists (p-value=0.01) and also patients themselves (p-value=0.03). Side effects were significantly higher in carbon dioxide fractional laser group as compared to micro needling (p-value=0.02). Conclusion: Significant number of patients respond well to carbon dioxide fractional laser treatment and the response included both expert opinion and patients own opinion, but adverse effects were seen more in same group. Therefore, better response but at the cost of more adverse effects was noted.

scholarly journals INTRAVENOUS REGIONAL ANESTHESIA (BIERS BLOCK);

2012 ◽  
Vol 19 (05) ◽  
pp. 710-714
Author(s):  
Muhammad ASGHER ◽  
ASIM GHAURI ◽  
MUHAMMAD ABDULLAH ◽  
Tariq Abassi
Keyword(s):  
Regional Anaesthesia ◽  
Military Hospital ◽  
P Value ◽  
Complete Evaluation ◽  
Intravenous Regional Anesthesia ◽  
Number Of Patients ◽  
Group A ◽  
The Mean ◽  
Group B ◽  
Intravenous Regional Anaesthesia

Objective: To compare the analgesic effects of combination of 0.5% Lidocaine plus Ketorolac in intravenous regionalanaesthesia technique with those of Lidocaine (0.5%) alone to prevent post operative pain after intravenous regional anaesthesia (Biersblock). Study design: Randomized Control Trial. Place and duration of study: The study was carried out at Department of Anaesthesiology,Intensive Care and pain management, Combined Military hospital, Rawalpindi from July 2008 to February 2009. Patients and Methods: Thestudy was conducted after complete evaluation of risk / benefit ratio to the patients. On the basis of random number method the patients weredivided into two equal groups (group A and group B). The number of patients in each group was 75. Group A was assigned Lidocaine in a dose of200mg 40ml of 0.5% solution and group B was assigned injection Ketorolac 30mg added to Lidocaine in a dose of 200mg 40ml of 0.5% solution.The patients were kept in post anaesthesia care unit for two hours and pain intensity was measured by visual analogue scale(VAS) on 15,30minutes,1hour, 1.5 and at 2 hours after the cuff deflation. The analgesic efficacy recorded on the basis of visual analog scale of two groups, wascompared using student’s t - test. p value of less than 0.05 was considered statistically significant. Results: In group A 33 males and 42 femaleswere enrolled for the study while in group B there were 38 males and 37 females. The mean age of the patients in group A was 34.31 ± 6.03years while in group B was 32.99 ± 6.08 years. Patients were also classified according to ASA classification in which 87 patients were classifiedas ASA – I and 63 patients as ASA – II. Group B which received Ketorolac in addition to Lidocaine for Bier’s block had low visual analogue scoresas compared to group A which received only Lidocaine for Bier’s block. P values obtained after the comparison of the mean VAS of two groupsat 15 minutes, 30 minutes, 1 hour, 1.5 hours and 2 hours were all less than 0.05 (0.002 for 15 minutes, 0.004 for 30 minutes, 0.001 for 1 hour,0.004 for 1.5 hours and 0.001 for 2 hours). Conclusions: Ketorolac improves the postoperative analgesia markedly when used with Lidocainein intravenous regional anaesthesia.

scholarly journals Fractional Ablative Carbondioxide Laser Resurfacing for Acne Scars - A Single Centered Study

2018 ◽  
Vol 1 (2) ◽  
pp. 79-81
Author(s):  
Rima Shrestha ◽  
Anupama Karki
Keyword(s):  
Carbon Dioxide ◽  
Effective Treatment ◽  
Carbon Dioxide Laser ◽  
Laser System ◽  
Monthly Interval ◽  
Fractional Laser ◽  
Monthly Basis ◽  
Improvement Rate ◽  
Severe Acne ◽  
Acne Scars

Introduction: Pulsed carbon dioxide laser devices are considered highly effective treatment options for skin resurfacing.  The aim of this study was to evaluate the efficacy and safety of an ablative 10,600-nm carbon dioxide fractional laser system on moderate to severe acne scarsMaterials and Methods: Forty participants (Fitzpatrick skin types III–IV) ranging from the age group of 25-45 who had moderate to severe acne scars were included in the study.CO2 Fractional laser was used, Unit: eCO2 Lutronic Korea; FDA approved, in 3 sessions at one month interval and 4th and 5th sessions at the interval of 2 months. Comparison was done on a monthly basis for the improvement of scars at one monthly interval and any other symptoms like pain, recovery time for wound healing and complications of laser like hyperpigmentation were noted by asking the patient to fill up a questionaire.Results: All the patients completed the treatment.At the end of the session participants experienced a reduction in the size of the scars. At the first laser session, they presented 10-25%, at the second session 20-45% and at the third session 30-60%. All participants felt an ascending improvement rate during and after the course of treatment. An average improvement of 71% was observed. Twelve of sixteen patients showed mild erythema which was transient and recovered at its own.Conclusions: Fractional Co2 laser ablation provides a safe and effective treatment of moderate to severe facial acne.

The Safe Delivery of Fractional Ablative Carbon Dioxide Laser Treatment for Acne Scars in Asian Patients Receiving Oral Isotretinoin

2014 ◽  
Vol 40 (12) ◽  
pp. 1361-1366 ◽  
Author(s):  
Hyun Woo Kim ◽  
Sung Eun Chang ◽  
Jeong Eun Kim ◽  
Joo Yeon Ko ◽  
Young Suck Ro
Keyword(s):  
Carbon Dioxide ◽  
Laser Treatment ◽  
Carbon Dioxide Laser ◽  
Safe Delivery ◽  
Asian Patients ◽  
Acne Scars ◽  
Oral Isotretinoin

scholarly journals COMPARISON OF MANIFESTATIONS OF GIARDIA AND ASCARIS INFESTATIONS BETWEEN BOTH GENDERS PRESENTING WITH DIARRHEA

2020 ◽  
Vol 70 (6) ◽  
pp. 1681-85
Author(s):  
Kanwal Jehanzeb ◽  
Zia Ul Haq ◽  
Saeed Zaman Khattak ◽  
Sajid Ali Shah ◽  
Munir Akmal Lodhi ◽  
...  
Keyword(s):  
Sampling Technique ◽  
Cross Sectional Study ◽  
Military Hospital ◽  
P Value ◽  
Common Symptom ◽  
Chi Square ◽  
Cross Sectional ◽  
Worm Infestation ◽  
Number Of Patients ◽  
Common Parasite

Objective: To assess the occurrence and intensity of Giardia and Ascaris infestations in children of both genders reporting with diarrhea. Study Design: Comparative cross sectional study. Place and Duration of Study: Paediatrics department, Combined Military Hospital, Gilgit, from Jul 2016 to Jul2018. Methodology: Patients of either gender with worm infestation were included in the study. Patients more than13 years old were excluded. The sampling technique used was non probability consecutive sampling. The stoolexamination (R/E) for the diagnosis of worm infestation was done. Stratification was done with regards to age,mother education, gender, type of water used and post stratification chi square test was applied. p-value was0.613 when calculated for the manifestation between both genders. p-value ≤0.05 was considered significant. Results: Total number of patients in our study was 100. Among them, males were 65 (65%) and females were 35(35%). Mean age of patients in our study was 4.20 ± 2.61 years (Mean ± SD). Abdominal pain being most common symptom in 43 (43%) of patients. Majority of the patients were from 2 to 10 years of age, 79 (79%). Helminthic infestation was the most common observed in 52 (52%) whereas Protozoal infestation was observed in 48 (48%) patients. The most common parasite isolated was Giardia 41 (41%) followed by Ascaris 36 (36%). p-value of 0.613 was found between both gender. Conclusion: In our study Helminthic infestation was more common. The most common parasite isolated wasGiardia followed by Ascaris.

scholarly journals Evaluation of adverse effects with COVID-19 vaccination in Pakistan

2021 ◽  
Vol 37 (7) ◽  
Author(s):  
Dr Sana Abbas ◽  
Beenish Abbas ◽  
Sidra Amir ◽  
Mehreen Wajahat
Keyword(s):  
Side Effects ◽  
Adverse Effects ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Post Vaccination ◽  
Gastrointestinal Disturbance ◽  
Creative Commons ◽  
Chi Square Test ◽  
Categorical Groups

Objectives: Vaccinations work with different mechanisms to offer protection against disease; however, process of immunity building can cause symptoms. Therefore, this study aimed to determine the immediate side effects of COVID–19 vaccination in the Pakistani Population. Methods: This cross-sectional analytical study was conducted at Foundation University College of Dentistry, Islamabad from February to April 2021. 0.5 mL per dose of the Covid-19 vaccine was administered to the candidates. These 205 candidates receiving vaccination were then interviewed investigating the adverse effects of the vaccine. Post-vaccination side effects were compared among categorical groups using the Chi-Square test, whereas post-vaccination side effects were compared with age using independent samples T-test. A p-value of ≤0.05 was statistically significant. Results: Among post-vaccination side effects, fever was reported by 69 participants, while 56 of 205 reported soreness, redness, and swelling at the injection site. It was reported by 42/205 participants to have felt chills and rigor, whereas gastrointestinal disturbance and flu-like symptoms were reported in 55/205 and 28/205 participants, respectively. Younger participants were more likely to develop gastrointestinal disturbance and flu-like symptoms following vaccination as compared to older participants. Conclusion: Malaise, headache, and fever were observed to be the most common side effects of the vaccine, moreover there was a linear relationship between manifestations of adverse effects and history of comorbidities. doi: https://doi.org/10.12669/pjms.37.7.4522 How to cite this:Abbas S, Abbas B, Amir S, Wajahat M. Evaluation of adverse effects with COVID-19 vaccination in Pakistan. Pak J Med Sci. 2021;37(7):---------.   doi: https://doi.org/10.12669/pjms.37.7.4522 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

scholarly journals PLASMAPHERESIS IN THE TREATMENT OF MYASTHENIA GRAVIS: OUTCOME AND COMPLICATIONS

2021 ◽  
Vol 71 (2) ◽  
pp. 396-400
Author(s):  
Maryam Abbas ◽  
Helen Mary Robert ◽  
Asad Mahmood ◽  
Salem Ahmed Khan ◽  
Mohammad Abdul Naeem ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Side Effects ◽  
Myasthenia Gravis ◽  
Tertiary Care ◽  
Military Hospital ◽  
P Value ◽  
Poor Outcome ◽  
Long Duration ◽  
First Session

Objective: To assess the outcome and complications of plasmapharesis in treatment of myasthenia gravis and factors linked to poor outcome at hematology unit of a tertiary care teaching hospital of Pakistan Study Design: Prospective comparative study. Place and Duration of Study: Pak Emirates Military Hospital/Armed Forces Institute of Pathology, Rawalpindi, from Jan 2018 to Jul 2019. Methodology: A prospective study was conducted on patients of myasthenia gravis presented at our neurology department. All the complications of the procedure were recorded. Outcomes included recovery, shifting to intensive care unit and death. Pearson chi-square was applied to relate the factors with presence of complications or poor outcome. Results: Hypotension 3 (6%) was the commonest complication faced by the patients followed by chest discomfort 2 (4%) during or after the plasmapharesis. Out of 50 patients, 47 (94%) recovered, 8 (16%) had minor complications, 2 (4%) were shifted to the intensive care unit and 1 (2%) died. Long duration of time between onset of symptoms and first session of plasmapharesis had a significant relationship (p-value <0.05) with presence of complications or poor outcome among the patients of myasthenia gravis undergoing plasmapharesis. Conclusion: Plasmapharesis emerged as effective treatment for this immune based neurological disorder with limited side effects. A neurologist should be aware of these common minor and rare major side effects and pay special attention to the patients with generalized myasthenia gravis and those with long duration of time between onset of symptoms and first session of plasmapharesis.Keywords:  ,.

scholarly journals Combined fractional laser treatment with 1550-nm erbium glass and 10 600-nm carbon dioxide lasers

2010 ◽  
Vol 21 (4) ◽  
pp. 221-223 ◽  
Author(s):  
Sung Bin Cho ◽  
Sang Ju Lee ◽  
Jin Moon Kang ◽  
Young Koo Kim ◽  
Sang Ho Oh
Keyword(s):  
Carbon Dioxide ◽  
Laser Treatment ◽  
Carbon Dioxide Lasers ◽  
Fractional Laser ◽  
Erbium Glass

Do New Antiepileptic Drugs with Novel Mechanisms of Action Suggest Reconsideration of Rational Polypharmacy?

US Neurology ◽  
2010 ◽  
Vol 06 (01) ◽  
pp. 70 ◽  
Author(s):  
Barry E Gidal ◽  
Keyword(s):  
Side Effects ◽  
Adverse Effects ◽  
Mechanisms Of Action ◽  
Rational Approach ◽  
Effective Control ◽  
Partial Seizures ◽  
New Antiepileptic Drugs ◽  
Number Of Patients ◽  
Seizure Models ◽  
Pharmacologic Effect

Although effective control of epilepsy can be achieved by a single antiepileptic drug (AED), the condition persists in a significant number of patients despite increasing dosages with monotherapy and polytherapy. Treatment with combinations of older AEDs has been known to cause undesirable drug–drug interactions and side effects. However, there has been renewed interest in polytherapy with the advent of newer AEDs with novel mechanisms of actions that are less likely to cause adverse effects in patients. Animal seizure models are useful for determining whether AEDs will be effective in generalised or partial seizures prior to clinical studies and isobolgraphic analysis may allow for a more systematic, rational approach to predicting whether a given combination of drugs will result in a greater or lesser pharmacologic effect. Since one treatment strategy does not suit all patients, studies should focus on the tolerability and safety of specific combinations of AEDs in order to provide guidance to physicians. In summary, pharmacokinetic interactions must be taken into account in studies in humans and animals with measurement of toxicity as well as efficacy.

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