Impact of Empowerment Intervention on Recovery and Symptoms Reduction in People with Schizophrenia

Background:Â Around one percent population is affected with Schizophrenia which is a severe mental illness. Typically onset is in late adolescence and remains for a lifetime. Objectives: The current study examined the impact of Empowerment intervention in Schizophrenia. Methods and Materials: This was a quasi-experimental, hospital-based intervention study, used purposive sampling to select 15 patients diagnosed with schizophrenia and admitted in Central Institute of Psychiatry, Ranchi.. Recovery Assessment Scale (RAS), Positive and Negative Syndrome Scale (PANSS) were administered. The study group received 6 sessions of empowerment intervention over a period of one month. Pre-post measurements were taken. Data were analysed using SPSS. Results: Findings suggested significant improvement in personal confidence, willingness, goal, reliance, and positive and negative syndrome than treatment as usual over a period of one month therapy. Conclusion: Empowerment intervention found to be effective in the management of schizophrenia. Findings indicate viable resource and pathways for future development are suggested.

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A mixed method evaluation of an intervention for parents with mental illness

Clinical Child Psychology and Psychiatry ◽

10.1177/1359104518822676 ◽

2019 ◽

Vol 24 (4) ◽

pp. 717-727 ◽

Cited By ~ 4

Author(s):

Darryl Maybery ◽

Melinda Goodyear ◽

Andrea Reupert ◽

Jade Sheen ◽

Warren Cann ◽

...

Keyword(s):

Mental Illness ◽

Family Functioning ◽

Mental Illnesses ◽

Control Treatment ◽

Wait List ◽

Structured Interviews ◽

Treatment As Usual ◽

Quasi Experimental ◽

And Control ◽

The Impact

Let’s Talk About Children is a manualised intervention for parents with a mental illness that aims to impact positively on family dynamics. Previous evaluations focused on parents with an affective disorder. The purpose of this study was to evaluate the intervention for parents with various mental illnesses and explore parents’ self-reported views regarding the impact of the intervention. A quasi-experimental approach was employed to compare outcomes for parents who received Let’s Talk About Children plus treatment as usual ( n = 20) with a wait list control (treatment as usual) group ( n = 19), using family functioning and parenting stress questionnaires. Questionnaires were completed 2 weeks prior to receiving the intervention and 4 to 6 weeks after the final session. The wait list parents completed the same questionnaires at two time periods, 6 weeks apart. Semi-structured interviews were conducted after the intervention. Both intervention and control groups showed improvements in parenting and family functioning. Interview data highlighted (1) increased insight, (2) normalising of the illness in the family, (3) family communication changes, (4) the importance of supporting the parenting role and (5) suggestions for additional supports. There are possible issues regarding the influence of psycho-education when giving participants information about the nature of the research.

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The Impact of Mindful Agency Coaching and Motivational Interviewing on the Development of Positive Learning Dispositions in Undergraduate Students: A Quasi-Experimental Intervention Study

Journal of Educational and Psychological Consultation ◽

10.1080/10474412.2019.1598266 ◽

2019 ◽

Vol 30 (1) ◽

pp. 63-89 ◽

Cited By ~ 2

Author(s):

Yanan Peng ◽

Qing Wang

Keyword(s):

Motivational Interviewing ◽

Undergraduate Students ◽

Intervention Study ◽

Experimental Intervention ◽

Quasi Experimental ◽

The Impact ◽

Learning Dispositions

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Subjective awareness of tardive dyskinesia and insight in schizophrenia

European Psychiatry ◽

10.1016/j.eurpsy.2009.12.006 ◽

2011 ◽

Vol 26 (5) ◽

pp. 293-296 ◽

Cited By ~ 16

Author(s):

R. Emsley ◽

D.J.H. Niehaus ◽

P.P. Oosthuizen ◽

L. Koen ◽

B. Chiliza ◽

...

Keyword(s):

Mental Illness ◽

Tardive Dyskinesia ◽

Rating Scale ◽

Subscale Score ◽

Domain Specific ◽

Subjective Awareness ◽

Syndrome Scale ◽

Mild Impairment ◽

Negative Syndrome ◽

Insight Into

AbstractBackgroundLack of awareness of tardive dyskinesia (TD) and poor insight into mental illness are common in schizophrenia, raising the possibility that these phenomena are manifestations of a common underlying dysfunction.MethodsWe investigated relationships between low awareness of TD and poor insight into mental illness in 130 patients with schizophrenia and TD. We also examined selected demographic and clinical correlates of these two phenomena.ResultsSixty-six (51%) patients had no or low awareness of TD and 94 (72%) had at least mild impairment of insight into their mental illness. Low awareness of TD was not significantly correlated with greater impairment of insight into mental illness. Regression analyses indicated that the Positive and Negative Syndrome Scale (PANSS) disorganised factor (β = 0.72, t = 11.88, p < 0.01) accounted for 52% of the variance in insight into mental illness (adjusted R2 = 0.55) (F[2, 127] = 81.00, p < 0.01) and the Extrapyramidal Symptom Rating Scale (ESRS) dyskinesia subscale score (β = 0.47, t = 6.80, p < 0.01), PANSS disorganised factor (β = −0.26, t = −3.73, p < 0.01), and ESRS parkinsonism subscale score (β = 0.31, t = 4.55, p < 0.01) together accounted for 37% of the variance in awareness of TD (adjusted R2 = 0.37) (F[3, 126] = 26.87, p < 0.01).ConclusionThe two phenomena appear to be dissociated, and may be domain-specific.

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Glycine attenuates impairments of stimulus-evoked gamma oscillation in the ketamine model of schizophrenia

10.1101/2021.04.15.439976 ◽

2021 ◽

Author(s):

Moritz Haaf ◽

Stjepan Curic ◽

Saskia Steinmann ◽

Jonas Rauh ◽

Gregor Leicht ◽

...

Keyword(s):

Clinical Benefit ◽

Negative Symptoms ◽

Large Body ◽

Gamma Band ◽

Similar Reduction ◽

Syndrome Scale ◽

Nmda Receptor Function ◽

Negative Syndrome ◽

Gamma Band Oscillations ◽

The Impact

Although a substantial number of studies suggests some clinical benefit concerning negative symptoms in schizophrenia through the modulation of NMDA-receptor function, none of these approaches achieved clinical approval. Given the large body of evidence concerning glutamatergic dysfunction in a subgroup of patients, biomarkers to identify those with a relevant clinical benefit through glutamatergic modulation are urgently needed. A similar reduction of the early auditory evoked gamma-band response (aeGBR) as found in schizophrenia patients can be observed in healthy subjects in the ketamine-model, which addresses the putative excitation / inhibition (E/I) imbalance of the diseases. Moreover, this change in gamma-band oscillations can be related to the emergence of negative symptoms. Accordingly, this study investigated whether glycine-related increases of the aeGBR accompany an improvement concerning negative symptoms in the ketamine-model. The impact of subanesthetic ketamine doses and the pretreatment with glycine was examined in twenty-four healthy male participants while performing a cognitively demanding aeGBR paradigm with 64-channel electroencephalography. Negative Symptoms were assessed through the Positive and Negative Syndrome Scale (PANSS). Ketamine alone caused a reduction of the aeGBR amplitude associated with more pronounced negative symptoms compared to placebo. Pretreatment with glycine attenuated both, the ketamine-induced alterations of the aeGBR amplitude and the increased PANSS negative scores in glycine-responders, classified based on relative aeGBR increase. Thus, we propose that the aeGBR represents a possible biomarker for negative symptoms in schizophrenia related to insufficient glutamatergic neurotransmission. This would allow to identify patients with negative symptoms, who might benefit from glutamatergic treatment.

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Destigmatized Group Intervention on Promoting Hope of Recovery: A Quasi-Experiment Study

Research on Social Work Practice ◽

10.1177/1049731519841432 ◽

2019 ◽

Vol 30 (1) ◽

pp. 54-64 ◽

Cited By ~ 1

Author(s):

Daniel K. W. Young ◽

Petrus Y. N. Ng ◽

Daphne Cheng

Keyword(s):

Mental Illness ◽

Repeated Measures ◽

Group Intervention ◽

Behavioral Therapy ◽

Assessment Tools ◽

Analysis Of Covariance ◽

Control Group ◽

Treatment As Usual ◽

Quasi Experimental ◽

Adults With Mental Illness

Objective: This research project aims to evaluate the effectiveness of a destigmatized group intervention in promoting hope of recovery for adults with mental illness. Methods: A quasi-experimental research method was adopted. In addition to treatment as usual (TAU), the treatment group ( n = 36) participated in a 10-session destigmatized group intervention, which was based on cognitive behavioral therapy (CBT), while the control group ( n = 42) received TAU. Standardized assessment tools were used for outcome assessment at the pretreatment and posttreatment periods. Results: The 2 × 2 repeated measures analysis of covariance demonstrated that participants who participated in the destigmatized group intervention experienced significantly fewer self-stigma and more hope of recovery. Additionally, multiple linear regression showed that the reduction of self-stigma predicted the promotion of hope of recovery. Conclusions: This study supports the effectiveness of the destigmatized group intervention, suggesting the importance of reducing self-stigma for facilitating recovery for adults with mental illness.

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Impact of primary negative symptoms on functional outcomes in schizophrenia

European Psychiatry ◽

10.1016/j.eurpsy.2014.01.007 ◽

2014 ◽

Vol 29 (7) ◽

pp. 449-455 ◽

Cited By ~ 86

Author(s):

G. Fervaha ◽

G. Foussias ◽

O. Agid ◽

G. Remington

Keyword(s):

Functional Outcomes ◽

Negative Symptoms ◽

Depression Scale ◽

Baseline Visit ◽

Syndrome Scale ◽

Quality Of Life Scale ◽

Life Scale ◽

Negative Syndrome ◽

The Impact

AbstractObjectiveNegative symptoms are known to undermine functional outcomes in people with schizophrenia; however, most studies have not accounted for whether these symptoms were primary or secondary to other psychopathological factors. The present study examined the impact of primary negative symptoms on functional outcomes in patients with schizophrenia.MethodThe sample included 1427 patients with schizophrenia who completed the baseline visit in the CATIE study. Symptoms were assessed with the Positive and Negative Syndrome Scale and Calgary Depression Scale, extrapyramidal side effects with the Simpson-Angus scale, and functional status with the Heinrichs-Carpenter Quality of Life Scale.ResultsNegative symptoms were significantly and inversely related to each domain of functioning examined. These relationships remained after statistically controlling for the influence of potential sources of secondary negative symptoms. In addition, the relationships between negative symptoms and specific domains of functioning remained in patients who had mild/absent positive, depressive, anxiety and extrapyramidal symptoms. Negative symptoms were associated with functional outcomes even in antipsychotic-free patients.ConclusionsPrimary negative symptoms significantly contribute to the functional impairment seen in people with schizophrenia. A better understanding of the etiology and pathobiology of these symptoms is required to guide the search for effective therapeutics that promote functional recovery.

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Effects of Adherence to Pharmacological Treatment on the Recovery of Patients with Schizophrenia

Healthcare ◽

10.3390/healthcare9091230 ◽

2021 ◽

Vol 9 (9) ◽

pp. 1230

Author(s):

Alejandra Caqueo-Urízar ◽

Alfonso Urzúa ◽

Patricio Mena-Chamorro ◽

Josefa Bravo de la Fuente

Keyword(s):

Negative Symptoms ◽

Positive Relationship ◽

Demographic Variables ◽

Antipsychotic Treatment ◽

Personal Recovery ◽

Attitude Inventory ◽

Syndrome Scale ◽

Recovery Assessment ◽

Drug Attitude Inventory ◽

Negative Syndrome

The aim of this study was to evaluate the effects of adherence to antipsychotic treatment on the recovery of patients with schizophrenia in northern Chile. One hundred and fifty-one patients diagnosed with schizophrenia completed the Drug Attitude Inventory (DAI-10), Positive and Negative Syndrome Scale for Schizophrenia (PANSS), Recovery Assessment Scale (RAS-24), sociodemographic information, and clinical and treatment characteristics of patients with schizophrenia. Multivariate analysis with multiple linear regression was then performed to identify variables that were potentially associated with the recovery assessment (variable criterion). A significant association was found between adherence to antipsychotic medication and the Willing to Ask for Help dimension of Recovery (β = 0.239, p = 0.005). Association of clinical and socio-demographic variables with recovery were identified: negative symptoms with Personal Confidence and Hope (β = −0.341, p = 0.001) and Goal and Success Orientation (β = −0.266, p = 0.014); cognitive symptoms with Willing to Ask for Help (β = −0.305, p = 0.018) and no domination by symptoms (β = −0.351, p = 0.005); marital status with reliance on others (β = −0.181, p = 0.045); age with Personal Confidence and Hope (β = −0.217, p = 0.021), Goal and Success Orientation (β = −0.296, p = 0.003), and no domination by symptoms (β = 0.214, p = 0.025). Adherence has a positive relationship with personal recovery in this sample of Chilean patients with schizophrenia.

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Anomalies of Imagination, Self-Disorders, and Schizophrenia Spectrum Psychopathology: A Network Analysis

Frontiers in Psychiatry ◽

10.3389/fpsyt.2021.808009 ◽

2022 ◽

Vol 12 ◽

Author(s):

Andreas Rosén Rasmussen ◽

Andrea Raballo ◽

Antonio Preti ◽

Ditte Sæbye ◽

Josef Parnas

Keyword(s):

Mental Illness ◽

Network Analysis ◽

Healthy Controls ◽

Schizophrenia Spectrum Disorders ◽

Schizotypal Personality ◽

Canonical State ◽

Schizophrenia Spectrum ◽

Syndrome Scale ◽

Spectrum Disorders ◽

Negative Syndrome

BackgroundAnomalies of imagination encompass disturbances of the basic experiential structure of fantasies and imagery that can be explored in a semi-structured way with the Examination of Anomalous Fantasy and Imagination (EAFI). We aimed (1) to examine the distribution of anomalies of imagination among different diagnostic groups and a group of healthy controls, and (2) to examine their relation with disorders of basic self, perceptual disturbances and canonical state psychopathology of the schizophrenia-spectrum (positive, negative and general symptoms).MethodsThe 81 participants included patients with schizophrenia or other non-affective psychosis (N = 32), schizotypal personality disorder (N = 15) or other mental illness (N = 16) and healthy controls (N = 18). The assessment encompassed EAFI, Examination of Anomalous Self-Experience (EASE), parts of Bonn Scale for the Assessment of Basic Symptoms (BSABS) and Positive and Negative Syndrome Scale (PANSS). For network analysis, the associations of EAFI with the other psychopathological variables were tested by Pearson's correlation coefficient and graphically represented using multidimensional clustering. Comparisons between correlations in the network were tested with Steiger's test.ResultsAnomalies of imagination aggregated significantly in schizophrenia-spectrum disorders compared to other mental illness and healthy controls with no difference between schizophrenia and schizotypal disorder. In the network analysis, anomalies of imagination were closely inter-connected with self-disorders. Although, the anomalies of imagination correlated moderately with perceptual disturbance and positive, negative and general state symptomatology, these dimensions aggregated separately and relatively distant in the network.ConclusionsThe results support that anomalies of imagination are highly characteristic of schizophrenia-spectrum disorders and closely related to self-disorders.

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Pengaruh Dukungan Kelompok Keluarga Sesama Penderita (family peer-led support group) terhadap Pencegahan Relaps Penderita Skizofrenia di Kabupaten Sleman, Yogyakarta

Journal of Nursing and Health ◽

10.25099/jnh.vol1.iss1.14 ◽

2019 ◽

Vol 1 (1) ◽

Author(s):

Abdul Ghofur

Keyword(s):

Treatment Group ◽

Support Group ◽

Bivariate Analysis ◽

Control Group ◽

Syndrome Scale ◽

Quasi Experimental ◽

Group A ◽

And Function ◽

Negative Syndrome ◽

Role And Function

Background. Psychoeducation conducted by professionals, not fully able to overcome the problems faced by families. Therefore, continuity of services at the community level has not run continuously and focused its efforts on empowering families in optimizing the role and function according to development tasks. Objectives. This study aims to determine the influence of the family support group of fellow patients (family peer-led support group) on the prevention of schizophrenia’s relapse. Method. This research method using a quasi-experimental design with pre and post control group. A sample of 36 families who have a schizophrenic patient who lived in Community Health Centres Godean I and Gamping II in Sleman district, which is divided into 18-person family in the treatment group and 18 families in the control group. Technics sampling with randomized control trials. Results. While indicators of relapse using the Positive and Negative Syndrome Scale (PANSS) before the intervention in the treatment group had a mean ± SD of 25.06 ± 11.79 after intervention mean ± SD of 24.28 ± 11.09; while the control group mean ± SD of 19.83 ± 5.38, after intervention mean ± SD of 27.61 ± 9.97. Based on bivariate analysis showed mean ± SD of 0.36 ± 6.40 (t: -2.112; Sig α (<0.05): 0.042; 95% CI: -16.788 to -0.322). Conclusion. Support family group of fellow patient (family peer-led support group) can reduce the risk of schizophrenia’s relapse.

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