SEX- AND AGE-RELATED SPECIAL FEATURES OF SPINAL CURVATURES IN THE FRONTAL PLANE IN CHILDREN AND YOUNG PEOPLE OF THE NORTHERN REGION WITH UNDIFFERENTIATED CONNECTIVE TISSUE DYSPLASIA

Author(s):  
N.A. Ilyushchenko ◽  
O.V. Ragozina ◽  
I.A. Shevnin ◽  
O.N. Ragozin
2021 ◽  
Vol 54 (2) ◽  
pp. 93-100
Author(s):  
Igor Andreevich Shevnin ◽  
Pavel Borisovich Tatarintsev ◽  
Olga V. Ragozina ◽  
Natalia A. Ilyushchenko ◽  
Oleg N. Ragozin ◽  
...  

Abstract. In connection with the spread of undifferentiated forms of connective tissue dysplasia (UCTD) in unfavorable climatogeographic and environmental conditions, it seems relevant to assess the impact of organogenesis disorders on physical development in schoolchildren living in the northern region. Based on the foregoing, the purpose of this study was to study the relationships and interdependencies of the components of physical development and somatometric indicators in children of the northern region with phenotypic signs of connective tissue dysplasia. Anthropometric indicators were revealed that can be used for express diagnostics of the level of physical development in children with UCTD these are the length of the legs, the thickness of the skin-fat fold on the front surface of the shoulder and the interorbital-circumferential index. When assessing covariants such as age and sex, there is a correlation of clusters of long-length values with age, the relationship of the thickness of the skin-fat folds with the floor, and the parameters assessing changes in the cerebral and facial skull, such as: face width, head circumference and interorbital-circumferential index are associated with both sex and with age. The influence of posture disorders on the studied components of physical development is manifested by higher growth in children with flat and round-curved backs, a decrease in the thickness of skin-fat folds and head size with a round and round-curved back. Thus, for a comparative analysis of gender and age differences in the level of physical development in children with UCTD, it is necessary to take into account the dynamics of interdependent anthropometric indicators and indices, taking into account postural disorders.


2019 ◽  
Vol 104 (8) ◽  
pp. 755-760 ◽  
Author(s):  
Lucy M. Alderson ◽  
Sandra X Joksaite ◽  
Jennifer Kemp ◽  
Eleanor Main ◽  
Tim Watson ◽  
...  

ObjectiveTo develop paediatric gait standards in healthy children and young people.MethodsThis observational study aims to address the lack of population standards for gait measurements in children. Analysing gait in children affected by neurological or musculoskeletal conditions is an important component of paediatric assessment but is often confounded by developmental changes. The standards presented here do not require clinician expertise to interpret and offer an alternative to developmental tables of normalised gait data. Healthy children aged 1–19 years were recruited from community settings in London and Hertfordshire, UK. The GAITRite walkway was used to record measurements for each child for velocity, cadence, step length, base of support and stance, single and double support (as percentage of gait cycle). We fitted generalised linear additive models for location, scale and shape (gamlss).ResultsWe constructed percentile charts for seven gait variables measured on 624 (321 males) contemporary healthy children using a gamlss package in R. A clinical application of gait standards was explored.ConclusionAge-related, gender-specific standards for seven gait variables were developed and are presented here. They have a familiar format and can be used clinically to aid diagnoses and to monitor change over time for both medical therapy and natural history of the condition. The clinical example demonstrates the potential of the Great Ormond Street Institute of Child Health Paediatric Gait Centiles to enable meaningful interpretation of change in an individual’s performance and describes characteristic features of gait from a specific population throughout childhood.


2021 ◽  
Vol 27 (2) ◽  
pp. 188-205
Author(s):  
M. E. Evsevyeva ◽  
M. V. Eremin ◽  
M. V. Rostovtseva ◽  
E. N. Fursova ◽  
A. V. Rusydi ◽  
...  

Objective. To assess the occurrence of various vascular aging phenotypes among young people, depending on the level of blood pressure (BP) and in relation to risk factors (RF) and the presence of connective tissue dysplasia (CTD).Design and methods. In total, 250 young people (88 boys and 162 girls) aged from 18 to 25 years old were examined at the University Health Center. All the subjects were divided into tercile groups based on cardio-ankle vascular index (CAVI), determined by the VaSera-1500 (Fucuda Denshia, Japan). According to the latest expert recommendations the third tercile group corresponds to early vascular aging or EVA syndrome. The first tercile group corresponds to favorable vascular aging. We have analyzed the representation of various vascular phenotypes in individuals with elevated and normal BP, as well as the main RF and external signs of CTD in each of CAVI-tercile group. Data processing was performed using the software package “Statistica 10.0” (StatSoft Inc., USA).Results. Among young people with office hypertension and high normal BP, the EVA phenotype and phenotypes of normal and favorable vascular aging are equally distributed. In persons with office normal and elevated BP, vascular stiffness correlates with weight, body mass index and waist circumference (with the increase in arterial rigidity these indicators decrease). CTD is registered among subjects with severe vascular remodeling both in boys and girls.Conclusions. Our data indicate the feasibility of angiology screening for identification of vascular aging phenotypes as a part of preventive measures among young people, regardless of the level of initial office BP. This strategy strategy will contribute to a more differentiated identification of risk groups and more individualized preventive interventions based on vascular aging phenotypes.


2021 ◽  
Vol 2021 ◽  
pp. 1-7
Author(s):  
Maria Shirshakova ◽  
Elena Morozova ◽  
Daria Sokolova ◽  
Svetlana Pervykh ◽  
Lyailya Kayumova

Undifferentiated connective tissue dysplasia is one of the most common diseases of nowadays, which does not fit into the group of hereditary syndromes. This condition is diagnosed in 20–50% of the population at any age. The study aimed to correct the facial soft tissues of patients with undifferentiated connective tissue dysplasia through the cosmetic procedure of calcium hydroxylapatite injection. In 2018, a 36-year-old patient addressed the beauty salon with signs of undifferentiated connective tissue dysplasia, such as severe asymmetry of the face, infraorbital and nasolabial sulci, and thin and easily folding skin. Signs were observed from the age of 22, i.e., for 14 years. The therapy was performed using special features of the correction of facial soft tissue changes in patients with connective tissue dysplasia (CTD) using calcium hydroxylapatite-based products (Radiesse®, Merz North America, Inc., USA). Particular attention is given to the need for early correction to prevent premature skin aging related to this condition. After 14 days, a significant improvement of the patient’s skin condition was noted after the passing of two procedures. Her condition was estimated as consistent with T1-2P0G0A1Zh1 P1M1K1 and corresponded to grade I age-related changes in the superficial soft tissues. The performed treatment showed high efficacy in case of mild connective tissue dysplasia diagnosis. The results showed that when collecting information from anamnesis, the diagnostic criteria for dysplasia should be considered. If the criteria are met, the cosmetological correction with collagen stimulators becomes possible.


2020 ◽  
Vol 19 (6) ◽  
pp. 2524
Author(s):  
M. E. Evseveva ◽  
M. V. Eremin ◽  
M. V. Rostovtseva ◽  
O. V. Sergeeva ◽  
E. N. Fursova ◽  
...  

Aim. To study the main risk factors and signs of connective tissue dysplasia (CTD) in young people according  to quartile analysis of cardioankle vascular index (CAVI).Material and methods. The study involved 243 young people (men, 81; women, 162) aged 18-25 years. All subjects were divided into quartile groups  depending  on CAVI on both sides,  or CAVI-R and CAVI-L, determined  using the VaSera-1500 system (Fucuda Denshia,Japan). According to the latest guidelines, the 4th  quartile of this distribution among persons  of the same sex and age corresponds to early vascular aging (EVA) syndrome.  The 1st  quartile corresponds to favorable vascular aging. We analyzed the main RFs and CTD signs in each  of the 4 CAVI quartiles. Data processing  was carried out using the Statistica 10.0 software package (StatSoft Inc,USA).Results. The minimum and maximum CAVI in the sample were 3,2 and 7,9. The overwhelming majority of studied risk factors in both sexes were not associated with the stiffness. Only body mass and body mass index increasedwith a decrease in vascular stiffness and vice versa. The average number of external stigmas of dysembryogenesis in young people increased from the 1st  to the 4th  CAVI quartile, with significant differences in the extreme groups. Such CTD signs as a carpal tunnel syndrome and thumb sign also significantly differed between the 1st  and 4th quartiles.Conclusion. The presented results can be used for prevention among young people to form more individualized programs taking into account a comprehensive assessment of vascular aging phenotype and the level of external stigmatization of each young person.


2020 ◽  
Vol 74 (2) ◽  
pp. 41-44
Author(s):  
O.N. Ragozin ◽  
◽  
I.A. Shevnin ◽  
N.A. Ilyushchenko ◽  
O.V. Ragozina ◽  
...  

The article presents the results of assessing the physical development of children 7–17 years old in the northern region with undifferentiated connective tissue dysplasia. It has been established that undifferentiated connective dysplasia affects the degree of harmony of physical development and the formation of pathological types of posture depending on gender and age, but does not affect gender and age differences in the rates of physical development.


2021 ◽  
Author(s):  
N.A. Ilyushenko ◽  
Yu.O. Gainutdinova ◽  
Z.B. Eskindyrova ◽  
O.V. Ragozina ◽  
I.A. Shevnin ◽  
...  

The article analyzes the data of an anthropometric and somatotypological study of 164 boys and 93 girls of the northern region, different sexual somatotypes with different severity of signs-phenes of undifferentiated connective tissue dysplasia. It was found that 44% of boys and 22% of girls with d, according to sexual somatic differentiation, correspond to the biological sex, 34% of boys and 53% of girls have mild gender dysplasia in the form of mesomorphy, and 19% of boys and 21% of girls have signs of sex inversion. Undifferentiated connective tissue dysplasia affects the severity of morphotypological differences between sexual somatotypes and the appearance of signs of gracialization within them. Key words: northern region, adolescence, sexual dimorphism, undifferentiated connective tissue dysplasia.


2021 ◽  
pp. 286-289
Author(s):  
A. A. Pantyushina ◽  
◽  
E. V. Ushakova ◽  
E. A. Zyuzina ◽  
◽  
...  

Quite recently, speaking about diseases of the knee joint, the discussion, as a rule, was about older people, more often, over 60 years old. Problems such as arthritis, arthrosis, acute arthrosis and other diseases arising from wear and tear of the joint during life came to mind. Nowadays, everything has changed since adolescence. Young people at the beginning of the XXI century, in connection with the development of scientific, technical and computer progress, increases physical inactivity, which leads to various diseases of the musculoskeletal system. Today, a very large number of young people suffer from knee diseases, the genesis of which is mainly post-traumatic or mediated by the growth of pathologies of the knee joint tissues. Injuries can occur due to accidents, but some of them can be triggered by the presence in patients of such chronic processes as connective tissue dysplasia. This disease significantly increases the risks of weakening the ligamentous apparatus of the joint. As a result, the likelihood of injury increases. The article presents the author’s complex of physiotherapy exercises for the restoration of the knee joint (A. A. Pantyushina) after injuries and related operations.


2019 ◽  
Vol 65 (2) ◽  
pp. 220-223
Author(s):  
I. Bagirov

Objective of the study: to assess the age-related dynamics of the incidences of ALL among children and young people in Azerbaijan during 1998-2014 years. Materials and methods of the study. Study has been held on the basis of the Azerbaijan Scientific and Research Institute of Haematology and Transfusiology named after B.A.Eyvazov where has been concentrated services of treatment and registration of patients with acute lymphoblastic leukemia. All patients under age of 30 years, determined during 1998-2014 years, have been observed. Diagnosis of ALL was confirmed in accordance with the program of the examinations, provided in the clinical protocols. Achieved results. In all periods of observation the highest value of the incidence of ALL in the 0-4 age group, which changed within the interval of 2,5 till 6,2In 5-9 years group morbidity rate of ALL varies within relatively narrow range: from 1,1 till 3,5. During 1998-2014 years in 10-14 years group morbidity rate of ALL also varies within relatively narrow range. Conclusions: The main trend of morbidity with ALL for all age groups is the tendency of increasing during 1998-2014 years.


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