scholarly journals Potency dependent activity of homeopathic nanomedicine- classical and quantum electrodynamical approach

2021 ◽  
Vol 16 (2) ◽  
pp. 01-04
Author(s):  
Papiya S Nandy
Keyword(s):  
Physical System ◽  
Trace Amount ◽  
Mechanical Energy ◽  
Mathematical Expression ◽  
Point Of View ◽  
High Dilution ◽  
Homeopathic Medicine ◽  
Physico Chemical ◽  
Dependent Activity ◽  
Membrane Barrier

The effect of homeopathic medicine on biological and physical system is directly related to its potency [1]. However, from physico-chemical point of view it is difficult to explain this effect at such high dilution, as then the existence of even trace amount of particle is questionable. It has been reported that during the process of potentization, a large amount of mechanical energy gets transferred to the medium due to succussion [2]. This energy in all probability reduces the size of the drug aggregates. The drug then penetrates easily through the membrane barrier, and thereby gives rise to enhanced activity of the medicine. It has been experimentally proved by us and supported by others that indeed a reduction of size of the aggregates takes place with increase in potency [3]. Using five different homeopathic medicines, their sizes at three different potencies have been estimated and a general mathematical expression relating the size of the particle (Y) and the corresponding potency (X) has been derived as follows Y = a X -n

scholarly journals Derivation of an empirical relation between the size of the nanoparticle and the potency of homeopathic medicines

2021 ◽  
Vol 14 (4) ◽  
pp. 02-07
Author(s):  
Subrat Kar ◽  
Poonam Bandyopadhyay ◽  
Sweta Chakraborty ◽  
Monalisa Chakrabarty ◽  
Biplab kumar Paul ◽  
...  
Keyword(s):  
Empirical Relation ◽  
Mathematical Expression ◽  
Point Of View ◽  
Standard Curve ◽  
Homeopathic Medicine ◽  
Physico Chemical ◽  
Aconitum Napellus ◽  
High Dilutions ◽  
Very High

Homeopathic medicines are often prescribed at very high dilutions and it is a clinically observed fact that the medicinal effect of the drug remains even at these high dilutions. The increase in potency of a medicine due to potentization is still debatable from physico-chemical point of view. Out of various hypotheses to explain this phenomenon, a recent hypothesis, advanced by us and supported by others, is that the size of the constituent particles decreases and eventually achieves nano dimension due to potentization. From the experiments performed by our group, the size of nanoparticles (NPs) of Cuprum metallicum, Zincum oxydatum, Aurum metallicum, Ferrum metallicum and Aconitum napellus (6cH, 30cH and 200cH) have been estimated. A general mathematical expression of the form y = a x-n has been derived which relates the size of NPs (y) with the corresponding potencies (x). There is no method to calculate the accurate potency of the homeopathic medicine, as the potency of a medicine depends to some extent on the method of preparation, for which a standardized procedure is warranted. Also, while handling a medicine, the solvent might evaporate causing a change in the potency. Thus by measuring the size of the NPs and using our proposed standard curve, the potency may be estimated.

scholarly journals I.—The Metamorphosis of the Lizard Gabbros

1886 ◽  
Vol 3 (11) ◽  
pp. 481-489 ◽  
Author(s):  
J. J. H. Teall
Keyword(s):  
Mechanical Energy ◽  
Earth Pressure ◽  
Careful Consideration ◽  
Point Of View ◽  
Igneous Rocks ◽  
General Point ◽  
Present Moment ◽  
General View ◽  
Original Rock ◽  
The Subject

If we take a general view of the present position of geological science, we are struck by the fact that, although there is substantial agreement amongst geologists on matters relating to the origin of the rocks usually designated as aqueous and igneous, the greatest diversity of opinion prevails with regard to the circumstances under which the so-called metamorphic rocks have been produced. Every fragment of evidence calculated to throw light on the origin of these rocks, therefore, deserves the most careful consideration. Of recent years special attention has been directed to the effects of mechanical energy in modifying the mineralogical and structural characters of rocks originally formed by aqueous and igneous agencies; and a suspicion has been aroused that it is in this direction that we must look for a solution of many of the problems connected with the origin of the crystalline schists. A visit to the Lizard Peninsula of Cornwall during the present summer has convinced me of the immense importance of this view so far as that district is concerned. That portion of the peninsula which lies south of a line drawn from Porthalla on the east to Polurrian Cove on the west is formed.partly of igneous rocks—such as gabbro, greenstone, serpentine, and granite—and partly of crystalline schists. The igneous rocks, in certain places, become foliated and sohistose and sometimes show a definite banding due to a variation in the relative proportions of the different constituents. In other words they present characters which are usually regarded as distinctive of the crystalline schists. There is, moreover, evidence to show that these characters are mainly the result of a yielding to earth-pressure subsequent to the consolidation of the original rock. At the present moment, having just returned from the district, I am unable to treat the subject from a general point of view with any prospect of success; but it has occurred to me that some details with regard to one of the rocks may not be without interest to members of the Association.

scholarly journals STUDY OF PHYSICOCHEMICAL CHARACTERISTICS OF BIRD VALLEY’S QUARRY WATER PCMC, MAHARASHTRA

2021 ◽  
Vol 6 (2) ◽  
pp. 18-24
Author(s):  
Shashikala Kokcha ◽  
Harsha Chatrath
Keyword(s):  
Seasonal Variations ◽  
Water Samples ◽  
Physicochemical Characteristics ◽  
Point Of View ◽  
Present Condition ◽  
Chemical Parameters ◽  
Standard Methods ◽  
Drinking Purposes ◽  
Physico Chemical ◽  
Methods And Techniques

Purpose of the study: The purpose of this study is to make sure that the Bird valley’s quarry water is suitable for drinking purposes or not and to monitor the seasonal variations in the physico-chemical parameters of this quarry water. Methodology: Water samples from the quarry were collected in clean and sterilized polyethylene bottles. Water samples were collected from different points and mixed together to get an integrated sample. Some of the selected physico-chemical parameters of the quarry water have been analyzed. Results were compared with standard limits of IS: 10500-2012. All the parameters were analyzed in the laboratory by using standard methods and techniques. Main Findings: As per the obtained results this quarry water contains a very large number of Coliforms detected in the months of September and December and in June month Coliform count was 33 CFU/ml. This overall result for coliform is making this quarry water unfit for domestic purposes. Applications of this study: This study helps us to understand the current condition of this quarry water and also enables us to know whether the quarry water is fit for drinking purposes. It also enables us to know whether this quarry water can be used for domestic purposes after the treatment. Novelty/Originality of this study: Bird valley’s quarry water has not been analyzed from this point of view till date. This study will help us to understand the present condition of the water.

Shape Memory Alloys Wires: From Small to Medium Diameter

2016 ◽  
Vol 101 ◽  
pp. 79-88 ◽  
Author(s):  
Vicenç Torra ◽  
Sara Casciati ◽  
Michele Vece
Keyword(s):  
Shape Memory Alloys ◽  
Shape Memory ◽  
Mechanical Energy ◽  
Critical Discussion ◽  
Point Of View ◽  
Hysteretic Behavior ◽  
External Temperature ◽  
Cold Temperatures ◽  
Thin Wires ◽  
Different Diameters

The use of Shape Memory Alloys in dampers devices able to reduce the wind, rain or traffic induced oscillations in stayed cables is well represented in the literature. An analysis realized on standard cables at existing facilities shows the reliable efficiency of the SMA wire in damping oscillations. Such studies also provide tools to build the SMA dampers and to account for the effects of the external temperature in the SMA. The particular study reported in this paper focuses on a critical discussion on the relation between the wire diameter and macroscopic behavior and external temperature effects. The damping requires the absorption of the mechanical energy and its conversion to heat via the action of hysteresis cycles. The study was realized on wires of different diameters. In particular, the study centers on wires of diameter 0.2, 0.5 and 2.46 mm. The flat cycles showed by the thin wires (i.e., diameter 0.2 and 0.5 mm) and the non-classical S-shaped cycles of wires of diameter 2.46 mm establish clear differences of the response under external summer-winter temperature actions. Depending of the room temperature and SMA composition, a complete flat transformation in thin wires requires stresses, in general, near 300-400 MPa. A complete transformation for an S-shaped cycle need stresses as higher as 600 MPa. The analysis of the behavior of these wires under the action of warm temperatures in summer and cold temperatures in winter, suggests that thin wires lose their pseudo-elastic state in winter. The S-shaped permits positive working in extended temperature domain and a supplementary investigation establishes that S-shaped can be increased by strain aging. The hysteretic behavior in S-shaped permits practical working under external temperatures as applications in bridges require. From a fundamental point of view, the flat cycles are coherent with the classical treatment of the SMA as a first order phase transition but the S-shaped can be considered associated to an anomaly in heat capacity.

scholarly journals Perspectives on the Use of Germinated Legumes in the Bread Making Process, A Review

2020 ◽  
Vol 10 (18) ◽  
pp. 6244
Author(s):  
Denisa Atudorei ◽  
Georgiana Gabriela Codină
Keyword(s):  
Wheat Flour ◽  
Point Of View ◽  
Bakery Products ◽  
Bread Making ◽  
Legume Seeds ◽  
Daily Diet ◽  
Germination Process ◽  
Physico Chemical ◽  
Different Types ◽  
Germinated Seeds

Nowadays, it may be noticed that there is an increased interest in using germinated seeds in the daily diet. This high interest is due to the fact that in a germinated form, the seeds are highly improved from a nutritional point of view with multiple benefits for the human body. The purpose of this review was to update the studies made on the possibilities of using different types of germinated legume seeds (such as lentil, chickpea, soybean, lupin, bean) in order to obtain bakery products of good quality. This review highlights the aspects related to the germination process of the seeds, the benefits of the germination process on the seeds from a nutritional point of view, and the effects of the addition of flour from germinated seeds on the rheological properties of the wheat flour dough, but also on the physico–chemical and sensory characteristics of the bakery products obtained. All these changes on the bread making process and bread quality depend on the level and type of legume seed subjected to the germination process which are incorporated in wheat flour.

scholarly journals Simple Approximate Formulas for Postbuckling Deflection of Heavy Elastic Columns

2020 ◽  
Vol 10 (20) ◽  
pp. 7163
Author(s):  
Hiroyuki Shima
Keyword(s):  
Mathematical Expression ◽  
Point Of View ◽  
Mathematical Methods ◽  
Concentrated Load ◽  
Combined Loads ◽  
Living Things ◽  
Buckling Behavior ◽  
Post Buckling ◽  
Analytical Formulas ◽  
Elastic Column

Columnar buckling is a ubiquitous phenomenon that occurs in both living things and man-made objects, regardless of the length scale ranging from macroscopic to nanometric structures. In general, analyzing the post-buckling behavior of a column requires the application of complex mathematical methods because it involves nonlinear problem solving. To complement these complex methods, this study presents simple analytical formulas for the large deflection of a heavy elastic column under combined loads. The analytical formulas relate the concentrated load acting on the tip of the column, the column’s own weight, and the deflection angle of the column through a simple mathematical expression. This can assist in obtaining an overall picture of the post-buckling behavior of heavy columns from an application point of view.

The Kirkendall Plane in Binary Interdiffusion Systems

2004 ◽  
Vol 233-234 ◽  
pp. 61-76 ◽  
Author(s):  
A.A. Kodentsov ◽  
A. Paul ◽  
F.J.J. van Loo
Keyword(s):  
Experimental Evidence ◽  
Kirkendall Effect ◽  
Point Of View ◽  
Chemical Approach ◽  
Diffusion Controlled ◽  
Physico Chemical ◽  
Considerable Body

There is now a considerable body of experimental evidence to indicate that in a volumediffusion controlled interaction the Kirkendall plane need not be unique. The Kirkendall plane can microstructurally be stable as well as unstable (it does not exist!). Under predictable circumstances, it can also bifurcate and even trifurcate. This can be rationalised in terms of Kirkendall velocity construction as well as from a purely chemical point of view considering diffusion-controlled interactions at the interphase interfaces. The physico-chemical approach is also used to explain significance of the Kirkendall effect in the morphogenesis of interdiffusion systems.

scholarly journals Separation of Biological Entities from Human Blood by Using Magnetic Nanocomposites Obtained from Zeolite Precursors

Molecules ◽  
2020 ◽  
Vol 25 (8) ◽  
pp. 1803
Author(s):  
Serena Esposito ◽  
Antonello Marocco ◽  
Gianfranco Dell’Agli ◽  
Barbara Bonelli ◽  
Franca Mannu ◽  
...  
Keyword(s):  
Human Blood ◽  
Chemical Properties ◽  
Industrial Process ◽  
High Sensitivity ◽  
Point Of View ◽  
The Novel ◽  
Magnetic Adsorbents ◽  
Physico Chemical ◽  
Magnetic Metal ◽  
Biological Entities

In this work, three novel magnetic metal–ceramic nanocomposites were obtained by thermally treating Fe-exchanged zeolites (either A or X) under reducing atmosphere at relatively mild temperatures (750–800 °C). The so-obtained materials were thoroughly characterized from the point of view of their physico-chemical properties and, then, used as magnetic adsorbents in the separation of the target gene factors V and RNASE and of the Staphylococcus aureus bacteria DNA from human blood. Such results were compared with those obtained by using a top ranking commercial separation system (namely, SiMAG-N-DNA by Chemicell). The results obtained by using the novel magnetic adsorbents were similar to (or even better than) those obtained by using the commercial system, both during manual and automated separations, provided that a proper protocol was adopted. Particularly, the novel magnetic adsorbents showed high sensitivity during tests performed with small volumes of blood. Finally, the feasible production of such magnetic adsorbents by an industrial process was envisaged as well.

scholarly journals Optimization of Curcumin Nanocrystals as Promising Strategy for Nose-to-Brain Delivery Application

Pharmaceutics ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 476 ◽  
Author(s):  
Angela Bonaccorso ◽  
Maria Rosa Gigliobianco ◽  
Rosalia Pellitteri ◽  
Debora Santonocito ◽  
Claudia Carbone ◽  
...  
Keyword(s):  
Desirability Function ◽  
Point Of View ◽  
Degree Of Crystallinity ◽  
Solubility In Water ◽  
Innovative Strategy ◽  
Drug Permeability ◽  
Physico Chemical ◽  
Mean Size ◽  
The Central Nervous System ◽  
Model Drug

Intranasal (IN) drug delivery is recognized to be an innovative strategy to deliver drugs to the Central Nervous System. One of the main limitations of IN dosing is the low volume of drug that can be administered. Accordingly, two requirements are necessary: the drug should be active at a low dosage, and the drug solubility in water must be high enough to accommodate the required dose. Drug nanocrystals may overcome these limitations; thus, curcumin was selected as a model drug to prepare nanocrystals for potential IN administration. With this aim, we designed curcumin nanocrystals (NCs) by using Box Behnken design. A total of 51 formulations were prepared by the sonoprecipitation method. Once we assessed the influence of the independent variables on nanocrystals’ mean diameter, the formulation was optimized based on the desirability function. The optimized formulation was characterized from a physico-chemical point of view to evaluate the mean size, zeta potential, polidispersity index, pH, osmolarity, morphology, thermotropic behavior and the degree of crystallinity. Finally, the cellular uptake of curcumin and curcumin NCs was evaluated on Olfactory Ensheathing Cells (OECs). Our results showed that the OECs efficiently took up the NCs compared to the free curcumin, showing that NCs can ameliorate drug permeability.

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