ASSESSMENT OF GEOCENTRIC DATUM OF MALAYSIA 2000 (GDM2000)

Abstract. Several major earthquakes that happened nearby Malaysia for the past decades resulted in a tectonic drift of the Sunda plate. Geocentric Datum of Malaysia 2000 (GDM2000) is affected and has shifted. This paper aims to assess the consistency of GDM2000 by computing datum shift caused by tectonic movement and reference frame effect. Daily solution coordinate of Malaysia Real-Time Kinematic Network (MyRTKnet) stations in the latest reference frame i.e ITRF2014 generated and a coordinate discrepancy between the current reference frame and publish coordinate provided by Jabatan Ukur dan Pemetaan Malaysia (JUPEM) are computed. The result shows that the datum has shifted with an average of 34.6 cm and moved with an average orientation of 111.1° toward the southeast direction. Therefore, this study will contribute to giving an overview of the current status of GDM2000.

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Video real-time imaging of artificial membranes during freeze-drying by cryo-electron microscopy

Proceedings, annual meeting, Electron Microscopy Society of America ◽

10.1017/s042482010010216x ◽

1988 ◽

Vol 46 ◽

pp. 16-17

Author(s):

Alan S. Rudolph ◽

Ronald R. Price

Keyword(s):

Real Time ◽

Self Assembly ◽

Freeze Drying ◽

Video Capture ◽

Drying Process ◽

Artificial Membranes ◽

The Past ◽

Cryo Electron Microscopy ◽

Spherical Structures ◽

Capture Techniques

We have employed cryoelectron microscopy to visualize events that occur during the freeze-drying of artificial membranes by employing real time video capture techniques. Artificial membranes or liposomes which are spherical structures within internal aqueous space are stabilized by water which provides the driving force for spontaneous self-assembly of these structures. Previous assays of damage to these structures which are induced by freeze drying reveal that the two principal deleterious events that occur are 1) fusion of liposomes and 2) leakage of contents trapped within the liposome [1]. In the past the only way to access these events was to examine the liposomes following the dehydration event. This technique allows the event to be monitored in real time as the liposomes destabilize and as water is sublimed at cryo temperatures in the vacuum of the microscope. The method by which liposomes are compromised by freeze-drying are largely unknown. This technique has shown that cryo-protectants such as glycerol and carbohydrates are able to maintain liposomal structure throughout the drying process.

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Contrast-enhanced ultrasound of the abdominal aorta – current status and future perspectives

VASA ◽

10.1024/0301-1526/a000749 ◽

2019 ◽

Vol 48 (2) ◽

pp. 115-125 ◽

Cited By ~ 4

Author(s):

Xin Li ◽

Daniel Staub ◽

Vasileios Rafailidis ◽

Mohammed Al-Natour ◽

Sanjeeva Kalva ◽

...

Keyword(s):

Real Time ◽

Vascular Diseases ◽

Aneurysm Rupture ◽

Vasa Vasorum ◽

Current Status ◽

Contrast Enhanced Ultrasound ◽

Aortic Diseases ◽

Cross Sectional ◽

Vascular Abnormalities ◽

Contrast Enhanced

Abstract. Ultrasound has been established as an important diagnostic tool in assessing vascular abnormalities. Standard B-mode and Doppler techniques have inherent limitations with regards to detection of slow flow and small vasculature. Contrast-enhanced ultrasound (CEUS) is a complementary tool and is useful in assessing both the macro- and microvascular anatomy of the aorta. CEUS can also provide valuable physiological information in real-time scanning sessions due to the physical and safety profiles of the administered microbubbles. From a macrovascular perspective, CEUS has been used to characterize aortic aneurysm rupture, dissection and endoleaks post-EVAR repair. With regard to microvasculature CEUS enables imaging of adventitial vasa vasorum thereby assessing aortic inflammation processes, such as monitoring treatment response in chronic periaortitis. CEUS may have additional clinical utility since adventitial vasa vasorum has important implications in the pathogenesis of aortic diseases. In recent years, there have been an increasing number of studies comparing CEUS to cross-sectional imaging for aortic applications. For endoleak surveillance CEUS has been shown to be equal or in certain cases superior in comparison to CT angiography. The recent advancement of CEUS software along with the ongoing development of drug-eluting contrast microbubbles has allowed improved targeted detection and real-time ultrasound guided therapy for aortic vasa vasorum inflammation and neovascularization in animal models. Therefore, CEUS is uniquely suited to comprehensively assess and potentially treat aortic vascular diseases in the future.

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Advances In Asthma Care

Californian Journal of Health Promotion ◽

10.32398/cjhp.v1i1.383 ◽

2003 ◽

Vol 1 (1) ◽

pp. 87-90 ◽

Cited By ~ 1

Author(s):

Chris Garvey

Keyword(s):

Healthcare Costs ◽

Professional Organizations ◽

Current Status ◽

Asthma Care ◽

Advanced Level ◽

Clinical Criteria ◽

Asthma Knowledge ◽

The Past ◽

The Us ◽

Examination Process

Asthma rates in the US have risen during the past 25 years, as have asthma-related morbidity and healthcare costs. Professional organizations involved in asthma care have identified the need to assure that an advanced level of asthma knowledge and skill is available to patients with asthma, their families, and insurers. This need led to development of the certification for asthma educators. The Certified Asthma Educator (AE-C) must meet specific clinical criteria and pass a standardized examination designed to evaluate knowledge and skill for providing competent asthma education and coordination. The development and current status of the Certified Asthma Educator examination process and content are discussed, as are goals of the certification

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Accurate Three Dimensional Coordinates Measurements Using Differential GPS Real Time Kinematic Mode

Iraqi Journal of Science ◽

10.24996/ijs.2018.59.2c.20 ◽

2018 ◽

Vol 59 (2C) ◽

Keyword(s):

Real Time ◽

Three Dimensional ◽

Differential Gps ◽

Real Time Kinematic

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Water resources management in Greece: current status and prospective outlook

Water Science & Technology ◽

10.2166/wst.1995.0693 ◽

1995 ◽

Vol 32 (9-10) ◽

pp. 267-272 ◽

Cited By ~ 1

Author(s):

A. Angelakis ◽

E. Diamadopoulos

Keyword(s):

Water Resources ◽

Water Resources Management ◽

Water Demand ◽

Treatment Plant ◽

Current Status ◽

Reclaimed Wastewater ◽

Resources Management ◽

The Past ◽

Precipitation Water ◽

Pollution Loads

The basic aim of this paper is to present the existing conditions and problems of water resources management in Greece. Water demand has increased tremendously over the past 30 years. Despite adequate precipitation, water imbalance is often experienced, due to temporal and regional variations of the precipitation, the increased water demand during the summer months and the difficulty of transporting water due to the mountainous terrain. Integration of reclaimed wastewater originating from the wastewater treatment plant effluents into the water resources management is proposed. This plan exhibits the potential for reducing the pollution loads entering sea or inland waters, while at the same time providing water for irrigation.

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THE INTEGRATION OF GEOGRAPHY INFORMATION SYSTEM (GIS) AND GLOBAL NAVIGATION SATELITE SYSTEM-REAL TIME KINEMATIC (GNSS-RTK) FOR LAND USE MONITORING

International Journal of Geomate ◽

10.21660/2017.36.2768 ◽

2017 ◽

Vol 13 (36) ◽

Cited By ~ 5

Author(s):

Komara Djaja

Keyword(s):

Land Use ◽

Information System ◽

Real Time ◽

Geography Information System ◽

Real Time Kinematic ◽

Global Navigation ◽

Geography Information ◽

Land Use Monitoring

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Upcoming Drifts In Bio-Similars

Current Clinical Pharmacology ◽

10.2174/1574884715666200507131943 ◽

2020 ◽

Vol 15 ◽

Author(s):

Geeta Aggarwal ◽

Manju Nagpal ◽

Ameya Sharma ◽

Vivek Puri ◽

Gitika Arora Dhingra

Keyword(s):

Metabolic Diseases ◽

Market Competition ◽

Current Status ◽

Medicinal Products ◽

The Past ◽

Biologic Activity ◽

Emerging Trends ◽

Regulatory Guidelines ◽

Food Drug Administration ◽

Insight Into

Background: Biopharmaceuticals such as Biologic medicinal products have been in clinical use over the past three decades and have benefited towards the therapy of degenerative and critical metabolic diseases. It is forecasted that market of biologics will be going to increase at a rate of 20% per year, and by 2025, more than ˃ 50% of new drug approvals may be biological products. The increasing utilization of the biologics necessitates for cost control, especially for innovators products that have enjoyed a lengthy period of exclusive use. As the first wave of biopharmaceuticals is expired or set to expire, it has led to various opportunities for the expansion of bio-similars i.e. copied versions of original biologics with same biologic activity. Development of biosimilars is expected to promote market competition, meet worldwide demand, sustain the healthcare systems and maintain the incentives for innovation. Methods: Appraisal of published articles from peer reviewed journals, PubMed literature, latest news and guidelines from European Medicine Agency, US Food Drug Administration (FDA) and India are used to identify data for review. Results: Main insight into the quality requirements concerning biologics, current status of regulation of biosimilars and upcoming challenges lying ahead for the upgrading of marketing authorization of bio-similars has been incorporated. Compiled literature on therapeutic status, regulatory guidelines and the emerging trends and opportunities of biosimilars has been thoroughly stated. Conclusion: Updates on biosimilars will support to investigate the possible impact of bio-similars on healthcare market.

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Between Jerusalem and Athens

10.1093/oso/9780198746676.001.0001 ◽

2018 ◽

Cited By ~ 1

Author(s):

Nurit Yaari

Keyword(s):

Real Time ◽

Social Conditions ◽

Cultural Events ◽

Greek Drama ◽

The Past ◽

Key Points ◽

Mise En Scene ◽

Dramatic Writing ◽

Artistic Performance

How does a theatrical tradition emerge in the fields of dramatic writing and artistic performance? Can a culture, in which theatre played no part in the past, create a theatrical tradition in real time—and how? What was the contribution of classical Greek drama to the evolution of Israeli theatre? How do political and social conditions affect the encounter between cultures—and what role do they play in creating a theatre with a distinctive identity? This book, the first of its kind, attempts to answer these and other questions, by examining the reception of classical Greek drama in the Israeli theatre over the last seventy years. It deals with dramatic and aesthetic issues while analysing translations, adaptations, new writing, mise-en-scène, and ‘post dramatic’ performances of classical Greek drama that were created and staged at key points of the development of Israeli culture amidst fateful political, social, and cultural events in the country’s history.

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