scholarly journals Clinical Data, Comorbidities, and Mortality of COVID-19 in the State of Guanajuato, Mexico until May 20, 2020

2020 ◽  
Vol 9 (1) ◽  
Author(s):  
Nicolás Padilla-Raygoza ◽  
Efraín Navarro-Olivos ◽  
María De Jesús Gallardo-Luna ◽  
Francisco J Magos-Vázquez ◽  
Daniel Alberto Díaz-Martínez ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Odds Ratio ◽  
Regression Models ◽  
Ecological Study ◽  
The State ◽  
Age Group ◽  
Confounding Effect ◽  
Public Places ◽  
Logistic Regression Models ◽  
And Gender

Introduction: In December 2019, cases of pneumonia of unknown cause arose in Wuhan, China. The causative agent was subsequently identified as 2019-nCoV and later called SARS-CoV-2. In Mexico, since January 2020 when the first cases were reported, the spread of the infection has occurred throughout the country. The state of Guanajuato, which is located in the center of the country, has taken isolation measures and closed public places in March 2020. The objective of this study was to analyze the evolution, symptoms, co-morbidities and deaths due to confirmed cases of COVID-19.Methods: An ecological study was designed from the database of confirmed cases of COVID-19 in the state of Guanajuato. Odds ratios and 95% confidence intervals were calculated for symptoms and co-morbidities in deaths of confirmed cases. Logistic regression models were generated adjusting for age group and gender.Results: Among the 838 confirmed cases in the state, cases with dyspnea and cyanosis showed more significant effect on death. Age group and gender had little involvement as confounders. For practically all comorbidities (including diabetes, hypertension, cardiovascular disease, chronic kidney disease, and immunosuppression), there was a significant effect (odds ratio greater than 2) on mortality from COVID-19. Age group showed a confounding effect on comorbidities and death, but not gender.Conclusion: The confirmed cases had more than twice the possibility of having comorbidities, compared with those who did not die.

scholarly journals Aging demographic profile in municipalities in the state of Pará, Brazil

2018 ◽  
Vol 71 (suppl 1) ◽  
pp. 591-598 ◽  
Author(s):  
Ana Cristina Viana Campos ◽  
Lucia Hisako Takase Gonçalves
Keyword(s):  
Regression Models ◽  
Ecological Study ◽  
Population Aging ◽  
The State ◽  
Socioeconomic Conditions ◽  
Demographic Differences ◽  
Significance Level ◽  
Logistic Regression Models ◽  
Segmentation Analysis ◽  
Vulnerability To Poverty

ABSTRACT Objective: To investigate socioeconomic and demographic differences regarding population aging in municipalities of the state of Pará, Brazil. Method: Ecological study with secondary demographic, socioeconomic and health data from the 144 municipalities of the state of Pará, Brazil. Data were treated with segmentation analysis, the Mann-Whitney U test and logistic regression models, with a significance level of p ≤ 0.05. Results: Segmentation analysis provided a single variable to describe aging in the municipalities of Pará and originated two clusters, the high and low aging rate ones, with 104 (72.22%) and 40 (27.78%) municipalities in each, respectively. The fitted model revealed an association between aging and per capita income (p = 0.021), vulnerability to poverty (p = 0.003), rich to poor ratio (p = 0.012) and density of people (p = 0.019). Conclusion: There is heterogeneity in the population aging among the municipalities of Pará, mainly regarding socioeconomic conditions and number of people living in the municipalities.

Demographic factors associated with missed follow-up among solid tumor patients treated at a large multi-site academic institution

2020 ◽  
Vol 16 (32) ◽  
pp. 2635-2643
Author(s):  
Samantha L Freije ◽  
Jordan A Holmes ◽  
Saleh Rachidi ◽  
Susannah G Ellsworth ◽  
Richard C Zellars ◽  
...  
Keyword(s):  
Cancer Patients ◽  
Odds Ratio ◽  
Regression Models ◽  
Tumor Patients ◽  
Logistic Regression Models ◽  
Factors Associated ◽  
Follow Up Care ◽  
Risk Patients ◽  
African American Race

Aim: To identify demographic predictors of patients who miss oncology follow-up, considering that missed follow-up has not been well studies in cancer patients. Methods: Patients with solid tumors diagnosed from 2007 to 2016 were analyzed (n = 16,080). Univariate and multivariable logistic regression models were constructed to examine predictors of missed follow-up. Results: Our study revealed that 21.2% of patients missed ≥1 follow-up appointment. African–American race (odds ratio [OR] 1.33; 95% CI: 1.17–1.51), Medicaid insurance (OR 1.59; 1.36–1.87), no insurance (OR 1.66; 1.32–2.10) and rural residence (OR 1.78; 1.49–2.13) were associated with missed follow-up. Conclusion: Many cancer patients miss follow-up, and inadequate follow-up may influence cancer outcomes. Further research is needed on how to address disparities in follow-up care in high-risk patients.

scholarly journals Sex Differences in the Association between Internet Usage and Overweight/Obesity: Evidence from a Nationally Representative Survey in Nepal

Sexes ◽  
2021 ◽  
Vol 2 (1) ◽  
pp. 132-143
Author(s):  
Juwel Rana ◽  
Md. Momin Islam ◽  
John Oldroyd ◽  
Nandeeta Samad ◽  
Rakibul Islam
Keyword(s):  
Odds Ratio ◽  
Regression Models ◽  
Internet Use ◽  
Adjusted Odds Ratio ◽  
Internet Usage ◽  
The Internet ◽  
Logistic Regression Models ◽  
Biological Sex ◽  
Obesity Interventions ◽  
Nationally Representative

Objective: To examine the associations between internet use and overweight/obesity in people aged 15–49 years in Nepal and the extent to which these associations differ by biological sex. Materials and methods: The study analyzed the nationally representative Nepal Demographic and Health Survey (NDHS) 2016 data. Multivariable ordinal logistic regression models were fitted to estimate the total effects of internet use (IU) in the last 12 months and frequency of internet use (FIU) in the last month on overweight/obesity adjusted for potential confounders. Results: Of the 10,380 participants, the prevalence of overweight/obesity by IU was 38% (95% confidence interval (CI): 35.9%, 40.1%) for males and 44.1% (95% CI: 41.6%, 46.6%) for female. The likelihood of overweight/obesity was significantly higher (adjusted odds ratio (aOR): 1.55; 95% CI: 1.40, 1.73; p < 0.001) among those participants who used the internet compared to the participants who did not use the internet in the last 12 months. Similar associations were observed when using the augmented measure of exposure-FIU in the last month. We observed the modification effect of sex in the associations of IU (p-difference < 0.001) and FIU (p-difference < 0.002) with overweight/obesity in Nepal. Conclusions: Our findings suggest that future overweight/obesity interventions in Nepal discourage unnecessary internet use, particularly among males.

Racial Disparities in Invasive Management for Patients With Acute Myocardial Infarction With Chronic Kidney Disease

2021 ◽  
Author(s):  
Jennifer A. Rymer ◽  
Shuang Li ◽  
Patrick H. Pun ◽  
Laine Thomas ◽  
Tracy Y. Wang
Keyword(s):  
Myocardial Infarction ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Racial Disparities ◽  
Odds Ratio ◽  
Adjusted Odds Ratio ◽  
Logistic Regression Models ◽  
Black Patients ◽  
Invasive Management ◽  
White Patients

Background: Due to increased risks of contrast nephropathy, chronic kidney disease (CKD) can deter consideration of invasive management for patients with myocardial infarction (MI). Black patients have a higher prevalence of CKD. Whether racial disparities exist in the use of invasive MI management for patients with CKD presenting with MI is unknown. Methods: We examined 717 012 White and 99 882 Black patients with MI treated from 2008 to 2017 at 914 hospitals in the National Cardiovascular Data Registry Chest Pain—MI Registry. CKD status was defined as estimated glomerular filtration rate (eGFR) ≥90 mL/(min·1.73 m 2 ; no CKD), eGFR <90 but ≥60 (mild), eGFR <60 but ≥30 (moderate), and eGFR <30 or dialysis (severe). We used multivariable logistic regression models to examine the interaction of race and CKD severity in invasive MI management. Results: Among those with MI, Black patients were more likely than White patients to have CKD (eGFR <90; 61.4% versus 58.5%; P <0.001). Among those with MI and CKD, Black patients were more likely than White patients to have severe CKD (21.2% versus 12.4%; P <0.001). Patients with CKD were more likely than those without CKD to have diabetes or heart failure; Black patients with CKD were more likely to have these comorbidities when compared with White patients with CKD (all P <0.0001). Black race and CKD were associated with a lower likelihood of invasive management (adjusted odds ratio, 0.78 [95% CI, 0.75–0.81]; adjusted odds ratio, 0.72 [95% CI, 0.70–0.74]; P <0.001 for both). At eGFR levels ≥10, Black patients were significantly less likely than White patients to undergo invasive management. Conclusions: Black patients with MI and mild or moderate CKD were less likely to undergo invasive management compared with White patients with similar CKD severity. National efforts are needed to address racial disparities that may remain in the invasive management of MI.

scholarly journals Movement Behaviors and Perceived Loneliness and Sadness within Alaskan Adolescents

2020 ◽  
Vol 17 (18) ◽  
pp. 6866
Author(s):  
Ryan D. Burns ◽  
Yang Bai ◽  
Christopher D. Pfledderer ◽  
Timothy A. Brusseau ◽  
Wonwoo Byun
Keyword(s):  
Mental Health ◽  
Odds Ratio ◽  
Regression Models ◽  
Movement Behavior ◽  
Youth Risk Behavior Survey ◽  
Association Analyses ◽  
Lower Odds ◽  
Logistic Regression Models ◽  
Race Ethnicity ◽  
Screen Use

Physical activity, screen use, and sleep are behaviors that integrate across the whole day. However, the accumulative influence of meeting recommendations for these 24-h movement behaviors on the mental health of Alaskan adolescents has not been examined. The purpose of this study was to examine the associations between movement behaviors, loneliness, and sadness within Alaskan adolescents. Data were obtained from the 2019 Alaska Youth Risk Behavior Survey (YRBS). The number of adolescents participating in the 2019 Alaska YRBS was 1897. Associations between meeting recommendations for movement behaviors with loneliness and sadness were examined using weighted logistic regression models, adjusted for age, sex, race/ethnicity, and body mass index (BMI). Approximately 5.0% of the sample met recommendations for all three movement behaviors. Meeting 2 or 3 movement behavior recommendations was associated with lower odds of loneliness (odds ratio (OR) range = 0.23 to 0.44, p < 0.01). Additionally, meeting 1 to 3 movement behavior recommendations was associated with lower odds of sadness (OR range = 0.29 to 0.52, p < 0.05). Joint association analyses determined that these relationships were primarily driven by meeting the sleep recommendation for loneliness and meeting the screen use recommendation for sadness. The results support use of multiple movement-based behavior programming to attenuate feelings of loneliness and sadness within Alaskan adolescents.

scholarly journals Effects of Older Adult Driving Resumption on All-Cause Mortality

2019 ◽  
Vol 75 (10) ◽  
pp. 2263-2267
Author(s):  
Kendra L Ratnapradipa ◽  
Jing Wang ◽  
Marla Berg-Weger ◽  
and Mario Schootman
Keyword(s):  
Logistic Regression ◽  
Older Adult ◽  
Mortality Risk ◽  
Odds Ratio ◽  
Regression Models ◽  
Adjusted Odds Ratio ◽  
Community Dwelling ◽  
Driving Cessation ◽  
Logistic Regression Models ◽  
All Cause Mortality

Abstract Objectives Driving cessation is associated with adverse social and health outcomes including increased mortality risk. Some former drivers resume driving. Do resumed drivers have a different mortality risk compared to former drivers or continued drivers? Method We analyzed National Health and Aging Trends Study (2011–2015) data of community-dwelling self-responding ever drivers (n = 6,189) with weighted stratified life tables and discrete time logistic regression models to characterize mortality risk by driving status (continued, resumed, former), adjusting for relevant sociodemographic and health variables. Results Overall, 14% (n = 844) of participants died and 52% (n = 3,209) completed Round 5. Former drivers had the highest mortality (25%), followed by resumed (9%) and continued (6%) drivers. Former drivers had 2.4 times the adjusted odds of mortality compared with resumed drivers (adjusted odds ratio [aOR] = 2.41; 95% confidence interval [CI] = 1.51, 3.83), with no difference between continued and resumed drivers (aOR = 1.22; 95% CI = 0.74, 1.99). Discussion Those who resumed driving had better survival than those who did not. Practice implications include driver rehabilitation and retraining to safely promote and prolong driving.

scholarly journals Teachers' opinion about the need for health promotion information

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
R Maceinaitė ◽  
G Šurkienė ◽  
R Sketerskienė
Keyword(s):  
Health Promotion ◽  
Health Information ◽  
Odds Ratio ◽  
Regression Models ◽  
Adjusted Odds Ratio ◽  
Teachers Perceptions ◽  
Logistic Regression Models ◽  
Health Promoting Schools ◽  
Health Promoting ◽  
The Subject

Abstract Background School is the most appropriate place for health promotion of pupils, which enables them to increase control over their health and improve it. Health promotion gives the best results when not only pupils but also their teachers are involved in the process, it is obvious that the success of health promotion depends on the teacher's attitude towards this process and his knowledge in this field. Aim of the study - to assess teachers' perceptions of the need for information on health promotion for themselves and their pupils. Methods 1247 teachers from 110 different schools in Lithuania were surveyed. Estimate of prevalence were calculated at 95% CI, logistic regression models were concluded, 95% CIs of adjusted odds ratio were calculated. Results 44.3% of teachers received sufficient amount of information on health promotion and 43.3% of them wanted more information on this subject. The odds of getting enough information on pupils health promotion were significantly related to teachers education, schools membership in Health Promoting Schools Network (HPSN) and location of school, the odds of wishing to get more information - with age and the subject teacher teaches. The most necessary information for teachers was information about healthy diet. They indicated that this information is most relevant to their pupils. In the opinion of the teachers, their pupils lack information on mental health. 71.6% of teachers were interested in information about health promotion. Interest in this subject was significantly related to gender, the subject teacher teaches and schools membership in HPSN. Conclusions Less than half of the respondents have received a sufficient amount of health promotion information and most of them are interested in this information, so it is important to provide teachers with health information that meets their needs. Providing teachers with health information it is important to take into consideration individual and school characteristics. Key messages Only less than half of teachers received sufficient amount of health promotion information. The majority of teachers were interested in information about health promotion.

scholarly journals Differential Methylation in APOE Genes (Chr19; exon four; from 44,909,188 to 44,909,373) and Increased Apolipoprotein E Plasmatic Levels in Subjects with Mild Cognitive Impairment”

2019 ◽  
Author(s):  
Oscar Mancera Páez ◽  
Kelly Estrada Orozco ◽  
Maria Fernanda Mahecha ◽  
Francy Cruz Sanabria ◽  
Kely Bonilla-Vargas ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Apolipoprotein E ◽  
Social History ◽  
Regression Models ◽  
Neuropsychological Testing ◽  
Logistic Regression Models ◽  
And Gender ◽  
Epigenetic Patterns ◽  
Risk Association

Background: Biomarkers are essential for identification of individuals at high risk of mild cognitive impairment (MCI) for potential prevention of dementia. We investigated DNA methylation in the ApoE gene and plasmatic apolipoprotein E (ApoE) levels as MCI biomarkers in Colombian subjects with MCI and controls. Methods: 100 participants were included (71% women, average age, 70 yrs., range 43-91). MCI was diagnosed by neuropsychological testing, medical and social history, activities of daily living, cognitive symptoms and neuroimaging. Multivariate logistic regression models adjusted by age and gender were performed to examine the risk association of MCI with plasma ApoE and APOE methylation Results: MCI was diagnosed in 41 subjects (average age, 66.5±9.6 yrs.) and compared with 59 controls. Elevated plasma ApoE and APOE methylation of CpGs 165, 190, and 198 were risk factors for MCI (P&lt;0.05). Higher CpG-227 methylation correlated with lower risk for MCI (P=0.002). Only CpG-227 was significantly correlated with plasmatic ApoE levels (correlation coefficient=-0.665; P=0.008). Conclusion: Differential APOE methylation and increased plasma ApoE levels were correlated with MCI. These epigenetic patterns can be used as potential biomarkers to identify early stages of MCI.

scholarly journals Multivariate regression analysis in the probability of deaths in COVID-19 cases: a case study in the State of Pará, Amazon region, Brazil

2020 ◽  
Vol 9 (11) ◽  
pp. e71291110299
Author(s):  
Cássio Pinho dos Reis ◽  
Herson Oliveira da Rocha ◽  
Nayara de Araújo Muzili Reis ◽  
Sávio Pinho dos Reis ◽  
Gustavo Nogueira Dias ◽  
...  
Keyword(s):  
Probabilistic Model ◽  
Odds Ratio ◽  
Multivariate Regression Analysis ◽  
The State ◽  
Metropolitan Region ◽  
Great Effort ◽  
Infected People ◽  
And Gender ◽  
The Impact

Since the first detected cases of COVID-19 in Brazil, researchers have made a great effort to try to understand the disease. Understanding the impact of the disease on people can be instrumental in identifying which groups can be considered at risk. Therefore, this study researches a probabilistic model based on a statistical model of non-linear regression analyzing the following variables: age, if you are a health professional, if you are resident in the Metropolitan Region of Belém (RMB), State of Pará and gender with the objective of identifying those people who have a greater impact on the number of people infected and killed by COVID-19, that is, people who are more likely to die. To carry out the research, we used the data of all infected people by COVID-19 in the State of Pará until July 2020. It can be verified according to the proposal of the probabilistic model that elderly people, with a odds ratio of 1.69 (95% CI 1.52-1.88), residents of Metropolitan Region of Belém, with an odds ratio of 2.14 (95% CI 2.02 - 2.27) and men, with an odds ratio of 1.83 (95% CI 1.73 - 1.95) are groups of people with a higher risk of dying from diseases, while health professionals, with a 0.36 chance ratio (CI9 5% 0.29 - 0.45), are less likely to die.

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