Effect of Resistance Exercise Training on Metabolic Syndrome and Depression in Elderly Women

2010 ◽  
Vol 42 ◽  
pp. 947-955
Author(s):  
Hee Jeong Son ◽  
Ji Hoon Kang
Keyword(s):  
Metabolic Syndrome ◽  
Exercise Training ◽  
Resistance Exercise ◽  
Elderly Women ◽  
Resistance Exercise Training

scholarly journals Resistance Exercise Training-Induced Muscle Hypertrophy Was Associated with Reduction of Inflammatory Markers in Elderly Women

2010 ◽  
Vol 2010 ◽  
pp. 1-7 ◽  
Author(s):  
Kishiko Ogawa ◽  
Kiyoshi Sanada ◽  
Shuichi Machida ◽  
Mitsuharu Okutsu ◽  
Katsuhiko Suzuki
Keyword(s):  
Exercise Training ◽  
Resistance Exercise ◽  
Elderly Women ◽  
Muscle Thickness ◽  
The Elderly ◽  
Low Grade ◽  
Resistance Exercise Training ◽  
Tnf Α ◽  
Low Grade Inflammation ◽  
Circulating Levels

Aging is associated with low-grade inflammation. The benefits of regular exercise for the elderly are well established, whereas less is known about the impact of low-intensity resistance exercise on low-grade inflammation in the elderly. Twenty-one elderly women (mean age ± SD, 85.0 ± 4.5 years) participated in 12 weeks of resistance exercise training. Muscle thickness and circulating levels of C-reactive protein (CRP), serum amyloid A (SAA), heat shock protein (HSP)70, tumor necrosis factor (TNF)-α, interleukin (IL)-1, IL-6, monocyte chemotactic protein (MCP-1), insulin, insulin-like growth factor (IGF)-I, and vascular endothelial growth factor (VEGF) were measured before and after the exercise training. Training reduced the circulating levels of CRP, SAA (P<.05), HSP70, IGF-I, and insulin (P<.01). The training-induced reductions in CRP and TNF-α were significantly (P<.01,P<.05) associated with increased muscle thickness (r=−0.61,r=−0.54), respectively. None of the results were significant after applying a Bonferroni correction. Resistance training may assist in maintaining or improving muscle volume and reducing low-grade inflammation.

scholarly journals Combined Exercise Training Performed by Elderly Women Reduces Redox Indexes and Proinflammatory Cytokines Related to Atherogenesis

2019 ◽  
Vol 2019 ◽  
pp. 1-9 ◽  
Author(s):  
André L. L. Bachi ◽  
Marcelo P. Barros ◽  
Rodolfo P. Vieira ◽  
Gislene A. Rocha ◽  
Paula B. M. de Andrade ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Exercise Training ◽  
Resistance Exercise ◽  
Proinflammatory Cytokines ◽  
Elderly Women ◽  
Plasma Lipid ◽  
Hdl Cholesterol ◽  
Moderate Intensity ◽  
Trained Group ◽  
Resistance Exercise Training

Cardiovascular benefits for the general population of combined aerobic-resistance exercise training are well-known, but the impact of this exercise training modality on the plasma lipid, inflammatory, and antioxidant status in elderly women that are exposed to a great risk of developing ischemic cardio- and cerebrovascular diseases has not been well investigated. So, we aimed to evaluate the plasma lipids, oxidative stress, and inflammatory cytokines in 27 elderly women (TRAINED group, 69.1±8.1 yrs) that were performing moderate intensity combined aerobic-resistance exercise training (3 times/week for at least 18 months) and in 27 sedentary elderly women (SED group, 72.0±6.4 yrs), not submitted to exercise training for at least 5 yrs. Our results showed that BMI was lower in the TRAINED group than in the SED group (25.1±3.2 vs. 28.7±5.1, p<0.05). The TRAINED group had lower glycemia (92±3 vs. 118±12, p<0.05), glycated hemoglobin (5.9±0.1 vs. 6.4±0.2, p<0.05), and triglycerides (98 (75-122) vs. 139 (109-214), p<0.01); equal total cholesterol (199 (175-230) vs. 194 (165-220)), LDL-cholesterol (108 (83-133) vs. 109 (98-136)), and non-HDL-cholesterol (54 (30-74) vs. 62 (26-80)); and also higher HDL-cholesterol (64 (52-77) vs. 52 (44-63), p<0.01) and LDL-C/oxLDL ratio (13378±2570 vs. 11639±3113, p<0.05) compared to the SED group. Proinflammatory cytokines as IL-1β (11.31±2.4 vs. 28.01±4.7, p<0.05), IL-6 (26.25±7.4 vs. 49.41±17.8, p<0.05), and TNF-α (25.72±2.8 vs. 51.73±4.2, p<0.05) were lower in the TRAINED group than in the SED group. The TRAINED group had lower total peroxides (26.3±7.4 vs. 49.0±17.8, p<0.05) and oxidized LDL (1551±50.33 vs. 1773±74, p<0.02) and higher total antioxidant capacity (26.25±7.4 vs. 49.41±17.8, p<0.001) compared to the SED group. In conclusion, in TRAINED women, BMI was lower, plasma lipid profile was better, plasma oxidative stress was diminished, and there was less expression of proinflammatory interleukins than in SED, suggesting that combined aerobic-resistance exercise training may promote the protection against the complications of ischemic cardio- and cerebrovascular disease in elderly women.

scholarly journals The effects of resistance exercise training on arterial stiffness in metabolic syndrome

2016 ◽  
Vol 116 (5) ◽  
pp. 899-910 ◽  
Author(s):  
E. DeVallance ◽  
S. Fournier ◽  
K. Lemaster ◽  
C. Moore ◽  
S. Asano ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Exercise Training ◽  
Arterial Stiffness ◽  
Resistance Exercise ◽  
Resistance Exercise Training

scholarly journals Type 2 Diabetes Reduces the Muscle Anabolic Effect of Resistance Exercise Training in Older Adults

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 529-529
Author(s):  
Amanda Randolph ◽  
Tatiana Moro ◽  
Adetutu Odejimi ◽  
Blake Rasmussen ◽  
Elena Volpi
Keyword(s):  
Type 2 Diabetes ◽  
Older Adults ◽  
Muscle Strength ◽  
Exercise Training ◽  
Resistance Exercise ◽  
Lean Mass ◽  
Synthesis Rate ◽  
Resistance Exercise Training ◽  
Appendicular Lean Mass

Abstract Type 2 Diabetes Mellitus (T2DM) accelerates the incidence and increases the prevalence of sarcopenia in older adults. This suggests an urgent need for identifying effective sarcopenia treatments for older adults with T2DM. It is unknown whether traditional approaches, such as progressive resistance exercise training (PRET), can effectively counteract sarcopenia in older patients with T2DM. To test the efficacy of PRET for the treatment of sarcopenia in older adults with T2DM, 30 subjects (15 T2DM and 15 age- and sex- matched controls) underwent metabolic testing with muscle biopsies before and after a 13-week full-body PRET program. Primary outcome measures included changes in appendicular lean mass, muscle strength, and mixed muscle fractional synthesis rate (FSR). Before PRET, BMI-adjusted appendicular lean mass was significantly lower in the T2DM group (0.7095±0.0381 versus 0.8151±0.0439, p&lt;0.0001). As a result of PRET, appendicular lean mass adjusted for BMI and muscle strength increased significantly in both groups, but to a lesser extent for the T2DM group (p=0.0009) . Preliminary results for FSR (n=25) indicate that subjects with T2DM had lower basal FSR prior to PRET (p=0.0197) . Basal FSR increased significantly in the control group after PRET (p=0.0196), while it did not change in the T2DM group (p=0.3537). These results suggest that in older adults the positive effect of PRET on muscle anabolism and strength is reduced by T2DM . Thus, older adults with T2DM may require more intensive, multimodal and targeted sarcopenia treatment. Funded by NIH R01AG049611 and P30AG024832.

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