scholarly journals Antibiotic Prophylaxis In Preventing Surgical Site Infection In Patients Undergoing Lichtenstein’s Hernioplasty

2018 ◽  
Vol 08 (03) ◽  
pp. 147-150
Author(s):  
Rizwanullah Junaid Bhanbhro ◽  
Khalil Ahmed Almani ◽  
Sadia Kazi
Keyword(s):  
Inguinal Hernia ◽  
Surgical Site Infection ◽  
Antibiotic Prophylaxis ◽  
Prophylactic Antibiotic ◽  
University Hospital ◽  
Site Infection ◽  
Inguinal Hernioplasty ◽  
Exclusion Criteria ◽  
Antibiotic Group ◽  
Low Incidence

Objective: To determine the antibiotic prophylaxis in preventing surgical site infection in patients undergoing Lichtenstein’s hernioplasty. Study design: Observational study Place and Duration: Department of surgery, ISRA University Hospital, Hyderabad. from December 2015 to March 2017. Materials and Methods: 120 cases of inguinal hernia planned for Lichtenstein’s hernioplasty were selected according to exclusion criteria and divided into control and antibiotic group. Pre- operative patient history, physical examination and inguinal hernia examination was performed. Prophylactic antibiotic ceftriaxone (1000 mg) was given over night of surgical procedure. Statistical software SPSS 21.0 was used for data analysis at 95% CI (P <0.05). Results: Mean± SD age was noted as 39.51 ± 7.56 years (15 – 61 years). Of 120, who underwent Lichtenstein’s hernioplasty the direct and indirect hernias were noted in 35 (29.16%) and 33 (27.5%) & 25 (20.83%) and 27 (22.5%) of control and antibiotic groups respectively. Of 120 subjects, the SSI was noted in 17 (14.1%) in control and 5 (4.16%) in antibiotic group. Cumulative SSI in 120 cases was 22 (18.33%). Conclusion: The present study reports low incidence of surgical site infection with antibiotic prophylaxis in Lichtenstein’s mesh repair in open inguinal hernioplasty.

scholarly journals P066 ELECTIVE LICHTENSTEIN INGUINAL HERNIOPLASTY IN GERIATRIC PATIENTS WITHOUT ANTIBIOTIC PROPHYLAXIS : HOW SAFE IS IT ?

2021 ◽  
Vol 108 (Supplement_8) ◽  
Author(s):  
Vladimir Cijan ◽  
Predrag Bojovic ◽  
Jovana Bojicic
Keyword(s):  
Placebo Group ◽  
Surgical Site Infection ◽  
Antibiotic Prophylaxis ◽  
Geriatric Patients ◽  
Operating Time ◽  
Prophylactic Antibiotic ◽  
Operation Time ◽  
Site Infection ◽  
Inguinal Hernioplasty ◽  
Elective Repair

Abstract Aim Elective surgery is becoming increasingly common in geriatric patients, particularly as the population is aging. The incidence of inguinal hernia in the elderly is also increasing. Lichtenstein inguinal hernioplasty is the most frequent procedure for the elective repair. There is ambiguity about the usefulness of antibiotic prophylaxis in inguinal mesh hernioplasty and the evidence for its value is still a matter of debate. Our aim was to evaluate the outcomes of Lichtenstein inguinal hernioplasty without antibiotic prophylaxis in geriatric patients. Material and Methods A database of patients aged 70 and more undergoing elective Lichtenstein inguinal hernioplasty was established. Patients were randomly categorized in antibiotic (received antibiotics) and placebo group (received placebo). Demographics, American Society of Anesthesiologists (ASA) classification, comorbidity, hernia type, operating time and hospitalisation were analyzed. Infections were evaluated 1 week, 2 weeks and 1 month postoperatively according to Center for Disease Control criteria. Results Between 2015.-2019., 400 patients were evaluated, 200 patients in each group. All patients were operated under local anaesthesia with 24-hours hospitalisation. Groups were well matched regarding demographics, ASA-type, comorbidity, hernia type, operation time. Superficial surgical site infection developed in 16 patients from the antibiotic and 19 from the placebo group. Three from each group developed deep infection. Two mesh removal was required in the placebo group. Conclusions Prophylactic antibiotic usage in geriatric patients undergoing Lichtenstein inguinal hernioplasty did not show any significant beneficial efects in reduction of surgical site infection. Our results do not support the routine use of antibiotics for elective inguinal hernioplasty.

scholarly journals ANTIBIOTIC PROPHYLAXIS IN BARIATRIC SURGERY: a continuous infusion of cefazolin versus ampicillin/sulbactam and ertapenem

2015 ◽  
Vol 52 (2) ◽  
pp. 83-87 ◽  
Author(s):  
Álvaro Antônio Bandeira FERRAZ ◽  
Luciana Teixeira de SIQUEIRA ◽  
Josemberg Marins CAMPOS ◽  
Guido Correa de ARAÚJO JUNIOR ◽  
Euclides Dias MARTINS FILHO ◽  
...  
Keyword(s):  
Surgical Site Infection ◽  
Antibiotic Prophylaxis ◽  
Continuous Infusion ◽  
Prophylactic Antibiotic ◽  
Surgical Site Infections ◽  
Anesthesia Induction ◽  
Site Infection ◽  
Cross Sectional ◽  
Group I ◽  
Bariatric Patients

Background The incidence of surgical site infection in bariatric patients is significant and the current recommendations for antibiotic prophylaxis are sometimes inadequate. Objective The aim of this study was to analyze the effect of three prophylactic antibiotic regimens on the incidence of surgical site infection. Methods A prospective, cross-sectional study was conducted between January 2009 and January 2013 in which 896 Roux-en-Y gastric bypasses were performed to treat obesity. The study compared three groups of patients according to the perioperative antibiotic prophylaxis administered intravenously and beginning at anesthesia induction: Group I consisting of 194 patients treated with two 3-g doses of ampicillin/sulbactam; Group II with 303 patients treated with a single 1-g dose of ertapenem; and Group III with 399 patients treated with a 2-g dose of cefazolin at anesthesia induction followed by a continuous infusion of cefazolin 1g throughout the surgical procedure. The rate of surgical site infection was analyzed, as well as its association with age, sex, preoperative weight, body mass index and comorbidities. Results The rates of surgical site infection were 4.16% in the group treated prophylactically with ampicillin/sulbactam, 1.98% in the ertapenem group and 1.55% in the continuous cefazolin group. Conclusion The prophylactic use of continuous cefazolin in surgeries for morbid obesity shows very promising results. These findings suggest that some prophylactic regimens need to be reconsidered and even substituted by more effective therapies for the prevention of surgical site infections in bariatric patients.

scholarly journals Long-term antibiotic prophylaxis regimen compared to short-term antibiotic prophylaxis regimen in patients undergoing orthognathic surgery

Medwave ◽  
2020 ◽  
Vol 20 (11) ◽  
pp. e8071-e8071
Author(s):  
Matthias Wallach ◽  
Javier Cuéllar ◽  
Francisca Verdugo-Paiva ◽  
Ana Alarcón
Keyword(s):  
Surgical Site Infection ◽  
Antibiotic Prophylaxis ◽  
Systematic Reviews ◽  
Orthognathic Surgery ◽  
Meta Analysis ◽  
Prophylactic Antibiotic ◽  
Cost Benefit ◽  
Site Infection ◽  
Short Term

INTRODUCTION Orthognathic surgery, being an invasive surgical procedure, may present significant postoperative morbidities for the patient. Among the most frequently described complications is surgical site infection. The administration of prophylactic antibiotics prior to this type of procedure is a common practice, however, the cost-benefit of the use of antibiotics, the type of antibiotics, the route of administration, the dosage, and the regimen to be used have not been clearly defined and are still considered a controversial issue. In this summary of evidence, we will compare long-term antibiotic prophylaxis with short-term prophylaxis. METHODS We searched in Epistemonikos, the largest database of systematic reviews in health, which is maintained by screening multiple information sources, including MEDLINE, EMBASE, Cochrane, among others. We extracted data from the systematic reviews, reanalyzed data of primary studies, conducted a meta-analysis and generated a summary of findings table using the GRADE approach. RESULTS AND CONCLUSIONS We identified five systematic reviews including nine studies overall, of which all nine were randomized trials. We conclude that administering a long-term prophylactic antibiotic regimen probably decreases the risk of surgical site infection and that it may increase the risk of hospital stay longer than two days, nevertheless, regarding this last point, the certainty of the evidence is low.

scholarly journals Antibiotic Prophylaxis in Elective Hand Surgery

2017 ◽  
Vol 45 (02) ◽  
pp. 089-093 ◽  
Author(s):  
Carolina Vasconcelos ◽  
Marta Serra ◽  
Rúben Nogueira ◽  
Leonor Carmo
Keyword(s):  
Retrospective Study ◽  
Surgical Site Infection ◽  
Antibiotic Prophylaxis ◽  
Infection Rate ◽  
Prophylactic Antibiotic ◽  
Hand Surgery ◽  
Diabetic Patients ◽  
Antibiotic Administration ◽  
Site Infection ◽  
Related Data

Purpose Antibiotic prophylaxis decreases the rate of surgical site infection in a broad spectrum of surgical procedures. However, in patients undergoing elective hand surgery, there is evidence of lower efficacy, and its use might be related to the development of antimicrobial resistance. The side effects and higher health-related costs must also be taken into consideration. Our aim was to assess the efficacy of antibiotic prophylaxis in these procedures. Material and methods A retrospective study was conducted including all patients who underwent clean, elective hand surgery lasting less than 30 minutes from January 1st 2014 to December 31st 2015 at our hospital. The demographic and surgery-related data were analyzed using the Statistical Package for the Social Sciences (SPSS, IBM Corp., Armonk, NY, US) software, version 23.0. Results A total of 346 patients matched the study's inclusion criteria. The infection rate was of 1%, and it was not influenced by gender, age or diabetes mellitus. Antibiotic prophylaxis was administered in 52% of the cases, and it had no effect on the decrease in the infection rate, even in the group of diabetic patients. Conclusions Despite the inherent limitations of any retrospective study, our data analysis supports the fact that prophylactic antibiotic administration does not reduce the incidence of surgical site infection in clean, elective hand surgery that lasts less than 30 minutes, even in patients at risk.

scholarly journals The efficacy of antibiotic prophylaxis in preventing SSI (surgical site infection) in patients undergoing Lichenstein’s hernioplasty at our tertiary care centre

2017 ◽  
Vol 4 (6) ◽  
pp. 1922
Author(s):  
Gowri Sankar Alagarsamy ◽  
Rajavelu Ramasamy
Keyword(s):  
Inguinal Hernia ◽  
Antibiotic Prophylaxis ◽  
Wound Infection ◽  
Tertiary Care ◽  
Site Infection ◽  
Care Centre ◽  
Inguinal Hernioplasty ◽  
Hernia Surgery ◽  
Tertiary Care Centre ◽  
Inguinal Hernia Surgery

Background: Inguinal hernia surgery is the commonest surgery performed worldwide. Lichtenstein tension free repair using polypropylene mesh is the gold standard procedure for inguinal hernioplasty. Wound infection is the most common complication encountered in inguinal hernia surgery. Antibiotic prophylaxis for open inguinal hernioplasty in minimizing wound infection has been a subject of debate since the beginning of mesh repair.Methods: This study is a randomized control trial (double blind study) designed to study the efficacy of antibiotic prophylaxis in preventing SSI (surgical site infection) in patients undergoing Lichenstein’s hernioplasty at our tertiary care centre.Results: The overall SSI incidence was found to be 12% in the study population. Among the placebo group, SSI was observed in 7 patients (14%). In the patients in whom antibiotic prophylaxis was administered, SSI was observed in 5 patients (10%).Conclusions: Antibiotic prophylaxis was associated with decreased incidence of wound infection when compared to control group, but the difference was not statistically significant. This study only gives a baseline data about the status of SSI associated with hernia repair in our tertiary care centre highlighting the need for further research in this field.

scholarly journals Protocol for a comparison study of 1-day versus 2-day prophylactic antibiotic administration in Holmium Laser enucleation of the prostate (HoLEP): a randomized controlled trial

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 161
Author(s):  
Katsumi Shigemura ◽  
Fukashi Yamamichi ◽  
Kento Nishimoto ◽  
Koichi Kitagawa ◽  
Masato Fujisawa
Keyword(s):  
Infectious Disease ◽  
Surgical Site Infection ◽  
Antimicrobial Prophylaxis ◽  
Prophylactic Antibiotic ◽  
University Hospital ◽  
Holmium Laser ◽  
Occurrence Rate ◽  
Antibiotic Administration ◽  
Site Infection ◽  
Prostate Hyperplasia

Background: The best method of antimicrobial prophylaxis administration for surgical site infection (SSI) in transurethral holmium laser resection and enucleation of the prostate (HoLEP)/bipolar transurethral enucleation (TUEB) remains controversial. The purpose of this study is to compare one-day and two-day cefazolin in a randomized 2nd-phase study to help establish a protocol with a 95% confidence interval (CI) for SSI prevention. Methods: Patients undergoing HoLEP/TUEB for benign prostate hyperplasia without preoperative pyuria will be enrolled and randomized to receive prophylactic antibiotic administration for HoLEP/TUEB in two groups, 1-day cefazolin and 2-day cefazolin. The primary endpoint is the occurrence rate of postoperative urinary tract infection or urogenital infection within 30 days after HoLEP/TUEB with a statistical 95% CI in comparison between those groups. Secondary outcomes include the kind of infectious disease and evidence of diagnosis, day of diagnosis of infectious disease, performance of urine or blood culture, detection of bacteria, treatments, duration of treatments, AEs other than surgical site infection, and drug-induced AEs. Discussion: The results of this study will provide evidence for defining the optimal duration of cefazolin prophylactic antibiotic administration for SSI. Trial registration: This study was registered in the University Hospital Medical Information Network-Clinical Trial Registry (UMIN000027955) based on recommendations from the International Committee of Medical Journal Editors (ICMJE) on July 1st 2017.

scholarly journals Evaluation of compliance with the antibiotic prophylaxis protocol in hysterectomy. Prospective cohort study

2020 ◽  
Vol 33 (3) ◽  
pp. 180-186
Author(s):  
Mario Gil-Conesa ◽  
Juan Antonio del-Moral-Luque ◽  
Nieves Climent-Martínez ◽  
Alberto Delgado-Iribarren ◽  
Rita Riera-Pérez ◽  
...  
Keyword(s):  
Cohort Study ◽  
Surgical Site Infection ◽  
Antibiotic Prophylaxis ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Public Health Problem ◽  
Epidemiological Surveillance ◽  
Site Infection ◽  
Low Incidence ◽  
The Moment

Objectives. Health care-related infections are a public health problem, among them surgical site infection (SSI) are the most frequent in hospitals. The objetive of this study was to assess the effect of the compliance to antibiotic prophylaxis protocol on the incidence of surgical site infection in hysterectomized patients. Material and methods. A prospective cohort study was carried out between October 2009 and December 2018. The incidence of SSI was studied after a maximum period of 30 days from the moment of surgery. The degree of adequacy of antibiotic prophylaxis in hysterectomy and the effect of its inadequacy on the incidence of infection was evaluated using relative risk (RR) adjusted with a logistic regression model. Results. A total of 1,025 interventions were studied in 1,022 women. The cumulative incidence of SSI was 2,1% (n = 22). The most frequent etiology of infection was Escherichia coli (23.1%) and Proteus mirabilis (23.1%). Antibiotic prophylaxis was indicated in 1,014 interventions (98.9%) being administered in 1,009 of them (99.5%). The adherence to the protocol was 92,5%. The main cause of non-compliance was the time of onset (40.9%), followed by the choice of the antibiotic (35.2%). The effect of inadequate prophylaxis on the incidence of infection was RR = 0.9; 95% CI 0.2-3.9; p> 0.05. Conclusions. The adequacy of antibiotic prophylaxis was very high, with a low incidence of surgical site infection. No association was found between adequacy of prophylaxis and incidence of infection in hysterectomy. The continuous improvement of epidemiological surveillance in gynecology should be emphasized.

scholarly journals Effect of single dose pre-operative antibiotic prophylaxis versus conventional antibiotic therapy in patients undergoing lichtenstein tension free mesh repair

2017 ◽  
Vol 4 (2) ◽  
pp. 738
Author(s):  
Madhu B. S. ◽  
Shashi Kumar H. B. ◽  
Naveen Kumar Reddy M. ◽  
Abilash V. Reddy ◽  
Sangeetha Kalabhairav
Keyword(s):  
Single Dose ◽  
Inguinal Hernia ◽  
Side Effects ◽  
Hernia Repair ◽  
Surgical Site Infection ◽  
Antibiotic Prophylaxis ◽  
Mesh Repair ◽  
Control Group ◽  
Site Infection ◽  
Tension Free

Background: Rational use of antibiotic is important as injudicious use can adversely affect the patient, cause emergence of antibiotic resistance and increase the cost of health care. The efficacy of antibiotic prophylaxis in preventing surgical site infection in patients undergoing Lichtenstein tension free inguinal hernia repair still remains controversial.Methods: A randomized controlled trial was conducted in patients undergoing lichtenstein tension free inguinal hernia repair between January 2015 to June 2016, and the results were compared with the control group in whom, conventional antibiotics were given for 7 days . All patients in study group undergoing surgery were given 400 mg parenteral ciprofloxacin 30 min prior to surgery. In the control group, the patients were given 2 days parenteral ciprofloxacin 400 mg twice a day and the next 5 days the same antibiotics were given in oral route, after surgery. Total 100 patients were randomized to 50 each group. The outcome in terms of duration of surgery, surgical site infection, cost and antibiotic side effects were then compared.Results: The duration of the hospital stay, cost and side effects are significantly higher in the control group patients. Antibiotic side effects (P < 0.05) were high for control group. The infection rate was same in both the groups. There was no significant difference in terms of infection rate among two groups.Conclusions: This study concludes that prophylactic single-dose antibiotic is effective in preventing surgical site infection and is cost-effective in patients undergoing lichtenstein tension free mesh repair.

scholarly journals Single dose antibiotic prophylaxis for prevention of surgical site infection in elective surgery

2017 ◽  
Vol 5 (1) ◽  
pp. 27 ◽  
Author(s):  
Swaroop V. Borade ◽  
Obaid Syed
Keyword(s):  
Surgical Site Infection ◽  
Antibiotic Prophylaxis ◽  
Elective Surgery ◽  
Prophylactic Antibiotic ◽  
Surgical Site Infections ◽  
Relevant Information ◽  
Site Infection ◽  
Intraoperative Management ◽  
Clean Contaminated ◽  
A Prospective Study

Background: Surgical site infections are associated with prolonged hospital stays and increased costs. Infection develops when endogenous flora is translocated to a normally sterile site. Seeding of the operative site from a distant site of infection can also occur (especially in patients with prosthesis or another implant). Factors influencing the development of surgical site infections include bacterial inoculums and virulence, host defences, preoperative care and intraoperative management. Hence there is the need for antibiotic prophylaxis to overcome this problem. This study was planned to evaluate the effect of prophylactic antibiotic in clean and clean contaminated cases and to assess the outcome.Methods: A prospective study was conducted which include 100 patients undergoing elective surgery admitted to the department of general surgery IIMSR’s Medical College and Hospital, Warudi, Jalna, relevant information of each patient was collected according to the Performa designed for the study. Cefuroxime was used preoperatively 30 min prior to incision and its impact on postoperative wound infection was studied.Results: We had 100 cases in our study predominantly males with maximum individuals in 31-40 years age group, we had 67% clean and 33% clean contaminated surgeries done and had 3% case of superficial surgical site infection.Conclusions: A single preoperative dose of antibiotic Cefuroxime is effective to prevent surgical site infection in elective case assuming an uncomplicated procedure.

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