scholarly journals Correlation Between Clinical Oral Dryness Score and Salivary Flow Rates in Active and Passive Smokers

2021 ◽  
Vol 10 (02) ◽  
pp. 120-123
Author(s):  
Seeme Nigar ◽  
Sobia Hassan ◽  
Sidra Fahim ◽  
Ahmed Bin Khalid ◽  
Faisal Salim
Keyword(s):  
Flow Rate ◽  
Smoking Status ◽  
Saliva Sample ◽  
Salivary Flow ◽  
Salivary Flow Rate ◽  
Significant Difference ◽  
Oral Dryness ◽  
The Mean ◽  
Potential Factors ◽  
Oral Dryness Feeling

Objective: To evaluate the mean clinical oral dryness score (CODs) and salivary flow rate (SFR) in subjects exposed to active and passive smoking. The secondary aim was to determine the correlation between CODs and SFR and potential factors associated with CODs and SFR in our subjects. Study Design and Setting: The clinical observational study was conducted at the Outpatient department of oral diagnosis at Altamash Institute of Dental Medicine, Karachi from Jan 2019-Jul 2019. Methodology: A total of 217 participants of ages 15 – 80years coming for routine dental checkup of either gender were included. A thorough oral examination was performed for all the subjects. A non-stimulated saliva sample was collected from the oral cavity of subjects in a graduated container. The salivary flow rate was noted in ml/min for 5 minutes. Assessment of oral dryness/hypo-salivation was examined through CODs (clinical oral dryness score).The data were analyzed using SPSS software version 23. Results: The mean COD score and SFR were calculated as 1 and 0.42 ml/5min respectively. The Pearson’s correlation between COD score and SFR level was calculated as -0.281 (negative correlation) such as the SFR significantly decreased when the COD score increased (p<0.05). The age, gender, smoking status, betel quid and areca nut consumption showed statistically significant difference in mean COD score and SFR levels (p<0.05). Conclusion: Salivary flow rate was significantly decreased with increase in COD score thus having an implication on oral dryness feeling in these participants.

scholarly journals Comparison of Salivary Calcium Level in Dentulous and Edentulous Patients

2019 ◽  
Vol 13 (01) ◽  
pp. 036-041
Author(s):  
Maryam Rabiei ◽  
Hamid Neshandar Asli ◽  
Mohadeseh Haji Mohamadi
Keyword(s):  
Flow Rate ◽  
Calcium Level ◽  
Calcium Concentration ◽  
Dental Health ◽  
Inverse Correlation ◽  
Salivary Flow ◽  
Salivary Flow Rate ◽  
Significant Difference ◽  
The Mean ◽  
Edentulous Patients

Abstract Objectives Calcium is an inorganic component of the saliva, which is especially important in oral and dental health. This study sought to compare unstimulated salivary calcium level of dentulous and edentulous patients. Materials and Methods This case–control study was conducted on 72 participants, including 36 dentulous and 36 edentulous patients. The unstimulated salivary flow rate of patients and the mean salivary calcium concentration were measured and compared. The data were analyzed using the nonparametric Mann–Whitney U-test. Results The mean age of participants was 56.3 years. The mean number of teeth was 18.9 in the dentulous group. No significant difference was noted in salivary calcium level of dentulous and edentulous patients. The mean salivary calcium concentration was 0.61 ± 0.3875 mmol/L in dentulous and 0.8025 ± 0.5975 mmol/L in edentulous patients. Salivary calcium level had a significant inverse correlation with salivary flow rate (r = –0.370, p = 0.027), and by every 1-unit increase in salivary flow rate, salivary level of calcium significantly decreased by 3.85 units. Conclusion Edentate had averagely higher salivary calcium level compared to dentulous. The salivary concentration of calcium ion is not correlated to the presence or absence of teeth. Salivary flow rate reduces the calcium concentration.

Stimulated whole salivary flow rate and composition in menopausal women with oral dryness feeling

Oral Diseases ◽  
2007 ◽  
Vol 13 (3) ◽  
pp. 320-323 ◽  
Author(s):  
F Agha-Hosseini ◽  
I Mirzaii-Dizgah ◽  
PP Moghaddam ◽  
ZT Akrad
Keyword(s):  
Flow Rate ◽  
Salivary Flow ◽  
Salivary Flow Rate ◽  
Menopausal Women ◽  
Oral Dryness ◽  
Oral Dryness Feeling

scholarly journals Effect of a newly developed pastille on the salivary flow rate in subjects with dry mouth symptoms: a randomized, controlled, monocentric clinical study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
S. Bielfeldt ◽  
D. Wilhelm ◽  
C. Neumeister ◽  
U. Schwantes ◽  
K. -P. Wilhelm
Keyword(s):  
Surface Tension ◽  
Flow Rate ◽  
Gum Arabic ◽  
Salivary Flow ◽  
Salivary Flow Rate ◽  
Dry Mouth ◽  
Main Ingredient ◽  
Control Product ◽  
Swallowing Problems ◽  
The Mean

Abstract Background Xerostomia is associated with several diseases and is a side effect of certain drugs, resulting from reduced saliva secretion. Often, aged and sometimes younger people suffer from (idiopathic) xerostomia. Chewing gum and sucking pastilles may relieve symptoms of xerostomia by increasing the salivary flow rate due to the mechanical effect of sucking and gustatory stimulation. Swallowing problems and the urge to cough or experiencing a tickling sensation in the throat might be alleviated through a reduction in dry mouth symptoms. We investigated whether a pastille containing four polysaccharides increased the salivary flow rate and relieved the symptoms of dry mouth. Methods Participating subjects with xerostomia were randomized into two equally balanced treatment groups. Subjects received the pastille on Day 1 and a control product (Parafilm®) on Day 3, or vice versa. Unstimulated saliva was collected every 2.5 min for 0–10 min. Stimulated saliva was collected after subjects sucked the pastille or the control product. The salivary flow rate was determined gravimetrically, and, in parallel, the feeling of dry mouth was assessed using a visual analog scale. Saliva surface tension was measured in pooled saliva samples (0–5 min of sampling). Additionally, in stimulated saliva from six subjects who sucked the pastille, the presence of the main ingredient—gum arabic—was examined by Raman spectroscopy. Results Chewing the pastille significantly increased the mean salivary flow rate by 8.03 g/10 min compared to the mean changes after chewing the control product (+ 3.71 g/10 min; p < 0.0001). The mean score of dry mouth was significantly alleviated by the pastille (− 19.9 ± 17.9 mm) compared to the control product (− 3.3 ± 18.1 mm). No difference between the two products was seen regarding the saliva surface tension. Gum arabic was present in the saliva of all investigated subjects for up to 10 min after sucking the pastille. Conclusions The pastille was well tolerated and effective in increasing the salivary flow rate and reducing mouth dryness after sucking. These results were in line with the detection of the main ingredient, gum arabic, in saliva for up to 10 min after sucking the pastille. Trial registration German Register Clinical Trials (Deutsches Register Klinische Studien, DRKS) DRKS-ID: DRKS00017393, Registered 29 May 2019, https://www.drks.de/drks_web/navigate.do?navigationId=trial. HTML&TRIAL_ID = DRKS00017393.

Association of Salivary Lipids and Early Childhood Caries in an Indian Subpopulation: A Preliminary Study

2019 ◽  
Vol 43 (6) ◽  
pp. 393-397
Author(s):  
Akhilesh Sharma ◽  
Mudunuri Sindhuja ◽  
Priya Subramaniam
Keyword(s):  
Flow Rate ◽  
Early Childhood Caries ◽  
Salivary Flow ◽  
Salivary Flow Rate ◽  
Total Lipids ◽  
Group Iii ◽  
Group I ◽  
The Mean ◽  
Preliminary Study ◽  
Group Ii

Aim: This preliminary study aimed to estimate and correlate the relationship between salivary flow rate and levels of salivary triglycerides, cholesterol and total lipids in children with and without early childhood caries. Study design: Ninety children aged 3 – 6 years were divided into three groups of 30 each based on their decayed missing filled tooth (dmft) score, group I (dmft score = 0), group II (dmft score ≥4 and ≤ 9) and group III (dmft scores ≥ 10). Whole unstimulated saliva was collected in a sterile graduated cup over a period of 5 minutes and was quantitatively analyzed for levels of salivary triglycerides, cholesterol and total lipids. Data obtained was subjected to statistical analysis by one way ANOVA, Post-Hoc tukey and Pearson’s correlation test. Results: Salivary flow rate was 1.20±0.36, 1.01±0.37 and 0.86±0.31 ml/min in group I, II and III respectively. The mean levels of salivary triglycerides in group I, II and III was 3.57±0.43mg/ml, 6.11±1.70mg/ml and 6.03±1.73 mg/ml, respectively. The mean levels of salivary total lipids were higher in group II and III, ie 22.51±2.87 mg/ml and 22.68±2.54 mg/ml respectively. The mean level of salivary cholesterol was highest in group III (8.03±2.91 mg/ml). Salivary triglycerides and total lipids showed a significant positive correlation with dmft scores of children (p≤ 0.001). Salivary cholesterol also had a positive association with dental caries experience of children but was not significant. There was a negative correlation between salivary flow rate and levels of salivary triglycerides, cholesterol and total lipids. Conclusion: Children with ECC (group II and III) had lower salivary flow rate and higher levels of salivary triglycerides and total lipids compared to caries free children (group I). Levels of salivary cholesterol did not differ between caries free and children with ECC.

Association Between Salivary Flow Rate and the Use of Systemic Medication Among 76-, 81-, and 86-year-old Inhabitants in Helsinki, Finland

1992 ◽  
Vol 71 (12) ◽  
pp. 1875-1880 ◽  
Author(s):  
T.O. Narhi ◽  
J.H. Meurman ◽  
A. Ainamo ◽  
J.M. Nevalainen ◽  
K.G. Schmidt-Kaunisaho ◽  
...  
Keyword(s):  
Flow Rate ◽  
Age Groups ◽  
Salivary Flow ◽  
Salivary Flow Rate ◽  
Flow Rates ◽  
Systemic Medication ◽  
Younger Age ◽  
Significant Difference ◽  
The Difference ◽  
Saliva Flow

The aim of this study was to examine salivary flow rate and its association with the use of medication in a representative sample of 76-, 81-, and 86-year-old subjects, totaling 368. In this study, 23% (n = 80) of the subjects were unmedicated. From one to three daily medications were used by 47% (n = 168) and more than four medications by 30% (n = 104). The most commonly used medications were nitrates, digitalis or anti-arrhythmic drugs (47.7%), analgesics and antipyretics (32.6%), and diuretics (29.5%). The mean number used daily was significantly higher in 86-year-olds than in the two younger age groups (p < 0.01). No significant differences in this respect were found between genders. Among the unmedicated subjects, 76-year-olds had significantly higher stimulated salivary flow rates than did the 81-year-olds (p < 0.05). Unmedicated women showed significantly lower unstimulated (p < 0.01) and stimulated flow rates than did men (p < 0.05). Stimulated salivary flow rate was also significantly higher in the 76-year-old medicated subjects than in the medicated 86-year-old subjects (p < 0.05). No statistically significant differences were found in unstimulated salivary flow rates among the three age groups. Medicated women showed significantly lower unstimulated salivary flow rates than men (p < 0.001), although the difference in stimulated saliva flow was not significant. A statistically significant difference in unstimulated and stimulated salivary flow rates was found between unmedicated persons and those who took from four to six, or more than seven, prescribed medications daily.

scholarly journals Pengaruh obat kumur beralkohol terhadap laju aliran saliva dan pH saliva

e-GIGI ◽  
2017 ◽  
Vol 5 (2) ◽  
Author(s):  
Feiby Rawung ◽  
Jane Wuisan ◽  
Michael A. Leman
Keyword(s):  
Oral Mucosa ◽  
Flow Rate ◽  
Salivary Flow ◽  
T Test ◽  
Salivary Flow Rate ◽  
Wilcoxon Test ◽  
Purposive Sampling ◽  
Significant Difference ◽  
Salivary Ph ◽  
Before And After

Abstract: Mouthwash is one of the accessible oral healthcare and practical for use by the community. Various commercial products contain more than one active ingredient; the most common one is alcohol with varied concentrations from 6% to 26%. Mouthwash with high concentration of alcohol can cause some effects to some users, like burning and dry sensation of the oral mucosa. Dry oral mucosa caused by reduced saliva production will be more susceptible to irritation. Reduced amount of saliva also causes lower oral pH which leads to increased growth of cariogenic bacteria. This study was aimed to investigate the influence of alcoholic mouthwash to salivary flow and salivary pH. This was a quasi-experiment study with before and after treatment groups. The population study was students of Dental Medical Education Program of Medical Faculty of University of Sam Ratulangi, Manado, batch 2012, with a total of 30 respondents obtained by using purposive sampling method. The T test showed that salivary flow rate before and after treatment had no significant difference (p >0.05) based on T test. Moreover, the Wilcoxon test showed that there was no significant difference of salivary pH between before and after treatment (p >0.05). Conclusion: There was no effect of rinsing with alcoholic mouthwash on salivary flow and salivary pH.Keywords: alcoholic mouthwash, salivary flow rate, salivary pH Abstrak: Obat kumur merupakan salah satu produk perawatan kesehatan gigi dan mulut yang mudah diperoleh dan praktis digunakan sendiri oleh masyarakat. Berbagai produk komersial mengandung lebih dari satu bahan aktif; salah satunya yaitu alkohol dengan konsentrasi bervariasi dari 6% hingga 26,9%. Kandungan alkohol yang tinggi dapat menimbulkan efek bagi sebagian pengguna, seperti sensasi terbakar dan kering di area mukosa mulut disebabkan berkurangnya saliva yang memudahkan terjadinya iritasi. Berkurangnya saliva juga menyebabkan pH mulut rendah sehingga pertumbuhan bakteri kariogenik meningkat. Penelitian ini bertujuan untuk mengetahui adanya pengaruh obat kumur beralkohol terhadap laju aliran saliva dan pH saliva. Jenis penelitian ialah eksperimen semu dengan kelompok sebelum dan sesudah perlakuan. Populasi penelitian yaitu mahasiswa Angkatan Tahun 2012 Program Studi Pendidikan Dokter Gigi, Fakultas Kedokteran, Universitas Sam Ratulangi Manado yang berjumlah 30 responden, diperoleh dengan purposive sampling. Hasil uji T berpasangan mennunjukkan data laju aliran saliva sebelum dan sesudah perlakuan tidak memiliki perbedaan bermakna (p >0,05). Berdasarkan uji Wilcoxon, data pH saliva sebelum dan sesudah perlakuan tidak memiliki perbedaan bermakna (p >0,05). Simpulan: Tidak terdapat pengaruh berkumur dengan obat kumur beralkohol terhadap laju aliran saliva dan pH saliva.Kata kunci: obat kumur beralkohol, laju aliran saliva, pH saliva

scholarly journals Saliva diagnostic utility in patients with type 2 diabetes: Future standard method

2019 ◽  
Vol 0 (0) ◽  
Author(s):  
Marwa Mrag ◽  
Asma Kassab ◽  
Asma Omezzine ◽  
Raoua Belkacem Chebil ◽  
Fatma Ben Fredj Ismail ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Flow Rate ◽  
Total Protein ◽  
Immunoglobulin A ◽  
Salivary Flow ◽  
Salivary Flow Rate ◽  
Oral Exam ◽  
Whole Saliva ◽  
Significant Difference

Summary Background The purpose of the present study was to assess saliva reliability in diagnosis and monitoring type 2 diabetes instead of blood. Methods Blood and unstimulated whole saliva were collected from 300 type 2 diabetic subjects and 300 healthy controls in fasting. Then, the salivary flow rate was calculated. All parameters including glucose, urea, amylase, total protein, albumin, C-reactive protein (CRP), immunoglobulin A (IgA), potassium, calcium and chloride were assessed in the supernatant, using an autoanalyzer. Oral exam was conducted by a single examiner on full mouth excluding third molars. Statistical analysis was performed by the SPSS 20.0 version. Results Saliva screening showed that glucose, urea, amylase, total protein, potassium, calcium and chloride were significantly higher in patients compared to controls (p < 0.05). Whereas, the IgA level and salivary flow rate were significantly reduced in patients (p < 0.05). No significant difference was found in albumin and CRP levels (p = 0.05). There was a significant positive correlation between salivary and plasma glucose levels (r = 0.887, and r = 0.900, p < 0.001), as well as, salivary and blood urea (r = 0.586, and r = 0.688, p < 0.001) in patients and controls, respectively. Conclusions From this study, saliva could be suggested as a useful diagnostic tool for type 2 diabetes.

scholarly journals Differences in the salivary inorganic ions levels and salivary flow rate of the periodontitis and non-periodontitis patients

2020 ◽  
Vol 32 (2) ◽  
Author(s):  
Rizki Amalina ◽  
Mahdalena Mahdalena ◽  
Grahita Aditya
Keyword(s):  
Calcium Phosphate ◽  
Flow Rate ◽  
Inorganic Ions ◽  
Salivary Flow ◽  
Salivary Flow Rate ◽  
Plaque Deposition ◽  
Periodontal Inflammation ◽  
Pathological Conditions ◽  
Significant Difference ◽  
Saliva Flow

Introduction: Saliva contains numerous proteins and electrolytes that may serve as biomarkers of pathological conditions, including periodontitis. Saliva flow also influenced by pathological conditions, such as periodontitis. Therefore, saliva analysis, as one of the biomarker source needs to be examined. This study was aimed to analyse the differences salivary inorganic ions levels (calcium, phosphate, and bicarbonate) and salivary flow rate in periodontitis and non-periodontitis patients. Methods: This research was analytic-observational using two groups, the healthy periodontal group consisting of 21 people (PI scores between 0-0.2) and the periodontitis group consisting of 21 people (PI scores between 0.7-8.0). Unstimulated saliva was collected using a passive drolling method. The calcium, phosphate and bicarbonate levels in the saliva were analysed using UV/Vis spectrophotometers. Results: Calcium, phosphate and bicarbonate levels in saliva were different between groups. Salivary flow rate also different between groups. There was a significant difference (p = 0.00) in the calcium, phosphate and bicarbonate levels between groups (t-test), and also significantly different (p = 0.000) salivary flow rate between groups. The higher the salivary flow rate, the higher the levels of calcium, phosphate and bicarbonate would be. Conclusion: Periodontitis condition increases the level of salivary inorganic ions and salivary flow rate because of periodontal inflammation. This inflammation mainly because of plaque deposition and calculus. Increased level of inorganic ions in the saliva such as calcium, phosphate, and bicarbonate, and also the salivary flow rate indicates the existence of a periodontal disease.

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