The Correlation between Physical Activity with Body Mass Index in Obesity Patient with Knee Osteoarthritis

In this study, we assessed the influences of change in moderate-to-vigorous physical activity (MVPA)/sedentary time (ST) of caregivers participating in a commercial weight-loss program on their children’s change in MVPA/ST. Data from 29 caregivers and their children were collected over 8 weeks. We used multivariable linear regression to assess associations of changes in caregiver’s percent of time spent in MVPA/ST and changes in their child’s percent of time spent in MVPA/ST. For caregivers that decreased body mass index (BMI) over 8 weeks, changes in caregivers’ MVPA was strongly associated with the change in children’s MVPA (β = 2.61 [95% CI: 0.45, 4.77]) compared to caregivers who maintained/increased BMI (β = 0.24 [–2.16, 2.64]). Changes in caregivers’ ST was strongly associated with changes in children’s ST (β = 2.42 [1.02, 3.81]) compared to caregivers who maintained/increased BMI (β = 0.35 [–0.45, 1.14]). Findings reinforce encouraging caregivers to enroll in weight-loss programs for the benefit of their children as well as for themselves.

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Physical activity, body mass index and arsenic metabolism among Mexican women

Environmental Research ◽

10.1016/j.envres.2021.110869 ◽

2021 ◽

Vol 195 ◽

pp. 110869

Author(s):

Brenda Gamboa-Loira ◽

Mariano E. Cebrián ◽

Lizbeth López-Carrillo

Keyword(s):

Physical Activity ◽

Body Mass Index ◽

Body Mass ◽

Mexican Women ◽

Arsenic Metabolism

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Relationship between Gender, Physical Activity, Screen Time, Body Mass Index and Wellbeing in Irish Children from Social-Disadvantage

Child Care in Practice ◽

10.1080/13575279.2021.1887815 ◽

2021 ◽

pp. 1-15

Author(s):

Wesley O’Brien ◽

Sarahjane Belton ◽

Ben Fitzpatrick ◽

Stephen Shannon ◽

Deirdre Brennan ◽

...

Keyword(s):

Physical Activity ◽

Body Mass Index ◽

Body Mass ◽

Screen Time ◽

Social Disadvantage

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Anthropometric Variables as Mediators of the Association of Changes in Diet and Physical Activity With Inflammatory Profile

The Journals of Gerontology Series A ◽

10.1093/gerona/glab072 ◽

2021 ◽

Author(s):

Gabriela Cárdenas-Fuentes ◽

Camille Lassale ◽

Miguel Ángel Martínez-González ◽

María Grau ◽

Jordi Salas-Salvadó ◽

...

Keyword(s):

Physical Activity ◽

Body Mass Index ◽

Body Mass ◽

Body Fat ◽

Controlled Trial ◽

High Sensitivity ◽

Linear Regression Models ◽

Mediating Role ◽

Inflammatory Score ◽

Inflammatory Profile

Abstract Background Mechanisms underlying the associations of high levels of physical activity (PA) and adherence to the Mediterranean diet (MedDiet) with a better inflammatory profile remain unclear. Our objective was to assess the mediating role of changes in body mass index (BMI) and waist circumference (WC), as markers of body fat in the association of changes in PA and adherence to the MedDiet, with changes in the inflammatory profile. Method This study included 489 adults, aged 55–75 years, from the PREDIMED-Plus multicenter lifestyle intervention trial. An inflammatory score was calculated, based on 8 blood biomarkers: high-sensitivity C-reactive protein, interleukin 6, interleukin 8, interleukin 18, monocyte chemo-attractant protein-1, C-peptide, leptin, and regulated on activation, normal T-cell–expressed and secreted chemokine. Biomarkers, levels of PA, score of MedDiet adherence, BMI, and WC were measured at baseline and at 1-year follow-up. Linear regression models were fitted according to the Baron and Kenny framework for mediation analysis. Results Changes in BMI and WC mediated the association of both changes in PA and changes in the MedDiet adherence with the inflammatory score. Body mass index mediated 26% of the association of changes in total PA with the inflammatory profile, and 27% of the association of changes in the MedDiet, while WC mediated 13% and 12% of these associations, respectively. Conclusion In older adults at high cardiovascular risk, increasing PA levels and adherence to a MedDiet during 1 year were associated with a lower inflammatory score, which was partly mediated by a reduction in body fat. Clinical Trials Registration Number International Standard Randomized Controlled Trial Number: ISRCTN89898870; registration date July 24, 2014, retrospectively registered.

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Physical Activity, Weight, and Outcomes in Patients Receiving Chemotherapy for Metastatic Breast Cancer (C40502/Alliance)

JNCI Cancer Spectrum ◽

10.1093/jncics/pkab025 ◽

2021 ◽

Author(s):

Jennifer A Ligibel ◽

Luke Huebner ◽

Hope S Rugo ◽

Harold J Burstein ◽

Debra L Toppmeyer ◽

...

Keyword(s):

Breast Cancer ◽

Physical Activity ◽

Body Mass Index ◽

Metastatic Breast Cancer ◽

Body Mass ◽

Hormone Receptor ◽

Metastatic Breast ◽

Hazard Ratio ◽

First Line ◽

Risk Of Cancer

Abstract Background Obesity and inactivity are associated with increased risk of cancer related- and overall mortality in breast cancer, but there are few data in metastatic disease. Methods CALGB 40502 was a randomized trial of first-line taxane-based chemotherapy for patients with metastatic breast cancer. Height and weight were collected at enrollment. After 299 patients enrolled, the study was amended to assess recreational physical activity (PA) at enrollment using the Nurses’ Health Study Exercise Questionnaire. Associations with progression-free survival (PFS) and overall survival (OS) were evaluated using stratified Cox modeling (strata included hormone receptor status, prior taxane, bevacizumab use, and treatment arm). Results 799 patients were enrolled and at the time of data lock, median follow-up was 60 months. At enrollment, median age was 56.7 years, 73.1% of participants had hormone receptor-positive cancers, 42.6% had obesity, and 47.6% engaged in less than 3 metabolic equivalents of task (MET)-hours of PA/week (<1 hour of moderate PA). Neither baseline body mass index nor PA was statistically significantly associated with PFS or OS, although there was a marginally statistically significant increase in PFS (hazard ratio = 0.83, 95% confidence interval [CI] = 0.79, 1.02; p = .08) and OS (hazard ratio = 0.81, 95% CI = 0.65, 1.02; p = .07) in patients who reported PA greater than 9 MET-hours/week vs 0–9 MET-hours/week. Conclusions In a trial of first-line chemotherapy for metastatic breast cancer, rates of obesity and inactivity were high. There was no statistically significant relationship between body mass index and outcomes. More information is needed regarding the relationship between PA and outcomes.

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