scholarly journals Is There a Relation Between Vitamin B₁₂ Levels and Headaches in Children and Adolescents?

2021 ◽  
Author(s):  
Müge Ayanoğlu ◽  
Hale Tuhan ◽  
Ayça Kömüroğlu ◽  
Ayşe Tosun
Keyword(s):  
Vitamin B12 ◽  
Children And Adolescents ◽  
Tension Type Headache ◽  
Control Group ◽  
Vitamin B ◽  
Primary Headaches ◽  
Healthy Children ◽  
Significant Difference ◽  
Type Headache ◽  
Lower Vitamin

Objective: Primary headaches are common and benign discomforts both in children and adolescents. However, they have a negative influence on the quality of life. This retrospective study aimed to determine the relationship between vitamin B12 results and primary headaches in Turkish children. Methods: Demographical features, headache types, laboratory results, including vitamin B12, were assessed retrospectively. Headache types were categorized as tension-type headache, migraine, and unclassified headache according to the International Classification of Headache Disorders-beta version (ICD-3 beta). Patients with seconder headaches, anemia, and macrocytosis were excluded. Results: The study group consisted of 133 (86 female, 47 male) patients with headache and a control group of 103 (57 female, 46 male) healthy children. There was no significant difference in terms of age and gender between groups (p>0.05). Vitamin B₁₂ levels in tension-type headache, migraine, and unclassified headache groups were significantly lower (p<0.0001) than in the control group. Logistic regression has identified lower vitamin B12 levels than 400 pg/ml as an independent risk factor for headache (OR: 3.212, 95% CI: 1.850-5.576). Conclusion: We conclude that lower vitamin B12 levels than 400 pg/mL may be associated with tension-type headache, migraine, and unclassified headache.

Psychopathology in children and adolescents with primary headaches: Categorical and dimensional approaches

Cephalalgia ◽  
2013 ◽  
Vol 33 (16) ◽  
pp. 1311-1318 ◽  
Author(s):  
Francesco Margari ◽  
Elisabetta Lucarelli ◽  
Francesco Craig ◽  
Maria G Petruzzelli ◽  
Paola A Lecce ◽  
...  
Keyword(s):  
Behavioral Problems ◽  
Child Psychopathology ◽  
Psychiatric Comorbidity ◽  
Primary Headache ◽  
Tension Type Headache ◽  
Emotional And Behavioral Problems ◽  
Control Group ◽  
Primary Headaches ◽  
Healthy Children ◽  
Type Headache

Background Recurrent headache is common in childhood, but there is not a great amount of data on the associations between headaches and psychopathology in children. Objective The aim of this study is to examine the relationships between primary headaches and psychopathology in children, using both the categorical and dimensional assessment. Methods The sample consisted of 70 patients with primary headache compared to a matched sample of 50 healthy children. Psychiatric comorbidity was defined according to the diagnostic criteria of the Diagnostic and Statistical Manual of Disorders. Child psychopathology outcomes were assessed using child- and parent-reported standardized instruments. Results Internalizing and externalizing problems were significantly represented among children with headaches compared to the control group, respectively 63% and 27%, without significant differences between migraine and tension-type headache children. Moreover, a total of 26% of the children with a headache reported psychiatric comorbidity such as anxiety and mood disorders. Conclusion The dimensional approach improves accuracy in the recognition of emotional and behavioral problems compared to the categorical approach; however, the use of both of these approaches could be useful for clinical practice, treatment and research.

scholarly journals Evaluation of Neutrophil-to-Lymphocyte Ratio, Platelet-to-Lymphocyte Ratio, and C-Reactive Protein in Tension-Type Headache Patients

2021 ◽  
Author(s):  
Hasan Hüseyin Özdemir ◽  
Ahmet Dönder
Keyword(s):  
Systemic Inflammation ◽  
Tension Type Headache ◽  
Neutrophil To Lymphocyte Ratio ◽  
Control Group ◽  
C Reactive Protein ◽  
Platelet To Lymphocyte Ratio ◽  
Lymphocyte Ratio ◽  
Reactive Protein ◽  
Significant Difference ◽  
Type Headache

Abstract Objectives A tension headache is the most common type of headache, and its causes are multifactorial. A relationship has been shown between migraine headaches and neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and C-reactive protein (CRP). In this study, we investigated the NLR, PLR, and serum CRP levels in frequent episodic tension-type headache (FETTH) and chronic tension-type headache (CTTH) patients. Materials and Methods This retrospective study included 64 patients with FETTH, 80 patients with CTTH, and 60 healthy controls who were followed up in the neurology clinic. Hematological parameters were compared between the patient and control groups. Results In CTTH patients, platelets, NLR, PLR, and CRP values were statistically higher than in FETTH patients and patients in the control group. In FETTH patients, the PLR value was higher than in patients in the control group, but there was no statistically significant difference in NLR and CRP values between FETTH patients and patients in the control group. Also, there was no correlation between these values and age and gender. Conclusion Increase platelet count might have an effect on tension-type headache pathophysiology. Systemic inflammation parameters were shown to be significantly higher in CTTH patients. More comprehensive studies are needed to evaluate the effect of systemic inflammation on the chronicity of tension headaches.

scholarly journals Evaluation of depression and self-esteem in children with monosymptomatic nocturnal enuresis: A controlled trial

2014 ◽  
Vol 86 (3) ◽  
pp. 212 ◽  
Author(s):  
Orhan Koca ◽  
Mehmet Akyüz ◽  
Bilal Karaman ◽  
Zeynep Yesim Özcan ◽  
Metin Öztürk ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Nocturnal Enuresis ◽  
Depression Scale ◽  
Self Esteem ◽  
Control Group ◽  
Case Group ◽  
Healthy Children ◽  
Significant Difference ◽  
Monosymptomatic Nocturnal Enuresis ◽  
Age Range

Objectives: Nocturnal enuresis (NE) is very common and is one of the most common causes for patients to be admitted to urology, pediatrics, child psychiatry and child surgery departments. We aimed to investigate the effect on depression and self-esteem of this disorder that can cause problems on person's social development and human relations. Material and methods: 90 patients who were admitted to our clinic with complaints of nocturnal enuresis were enrolled. Investigations to rule out organic causes were performed in this group of patients. Out of them 38 children and adolescents (age range 8-18 years) with primary monosymptomatic nocturnal enuresis (PMNE) agreed to participate in the study In the same period 46 healthy children and adolescents with a similar age range without bed wetting complaint were included in the study as a control group. The age of the family, educational and socioeconomic level were questioned and Piers-Harris Children's Self-Concept Scale (PHCSCS) and Children's Depression Inventory (CDI) forms were filled out. Results: Mean age of the cases (18 females or 47.4% and 20 males or 52.6%) was 10.76 ± 3.82 years whereas mean age of controls (26 females or 56.5% and 20 males or 43.5%) was 10.89 ± 3.11 years. Depression scale was significantly higher (p = 0.001) in the case group than in the control group (10.42 ± 4.31 vs 7.09 ± 4.35). In both groups there was no statistically significant difference by age and sex in terms of depression scale (p &gt; 0.05). Conclusion: NE is widely seen as in the community and is a source of stresses either for children and for their families. When patients were admitted to physicians for treatment, a multidisciplinary approach should be offered and the necessary psychological support should be provided jointly by child psychiatrists and psychologists.

Estimation of Antiphospholipid Antibodies in a Prospective Longitudinal Study of Children with Migraine

Cephalalgia ◽  
2004 ◽  
Vol 24 (10) ◽  
pp. 831-837 ◽  
Author(s):  
T Avcin ◽  
G Markelj ◽  
V Niksic ◽  
Z Rener-Primec ◽  
S Cucnik ◽  
...  
Keyword(s):  
Antiphospholipid Antibodies ◽  
Tension Type Headache ◽  
Control Group ◽  
Healthy Children ◽  
Prospective Longitudinal Study ◽  
Glycoprotein I ◽  
Patient Groups ◽  
Unselected Group ◽  
Type Headache ◽  
Prospective Longitudinal

The aim of this study was to determine the prevalence and clinical significance of antiphospholipid antibodies (aPL) in children with migraine. The values of anti-cardiolipin (aCL) and antiβ2 glycoprotein I (antiβ2GPI) antibodies were assayed by an ELISA method in 52 children with migraine and 22 children with tension-type headache. The control group consisted of 61 apparently healthy children at regular preventive visits. Two monoclonal β2GPI dependent aCL (HCAL and EY2C9) were used as calibrators. Lupus anticoagulant (LA) was determined by a modified dilute Russell viper venom time test. Persistently positive aPL were observed during the follow-up in 16.3% of children with migraine (9.3% for aCL, 7.0% for antiβ2GPI and 0% for LA) and in 16.7% of children with tension-type headache (11.1% for aCL, 5.6% for antiβ2GPI and 0% for LA). The prevalence of aPL did not differ significantly between patient groups and healthy children. The prevalence of aPL does not appear to be increased in an unselected group of children with migraine, however, the possible role of aPL in individual cases of paediatric migraine can not be excluded.

scholarly journals The relationship between tension headache and screen exposure in children and adolescents

2021 ◽  
Author(s):  
Jullyane Lutterbach Erthal ◽  
Caroline Matos de Souza Franco Rêgo
Keyword(s):  
Children And Adolescents ◽  
Screen Time ◽  
Technological Development ◽  
Muscle Tension ◽  
Tension Headache ◽  
Tension Type Headache ◽  
Moderate Intensity ◽  
Primary Headaches ◽  
Healthy Habits ◽  
Type Headache

Background: Primary headaches are idiopathic or genetic conditions without a known secondary cause. Primary tension-type headache is characterized by bilateral, non-throbbing pain, of mild to moderate intensity. Nowadays, with greater exposure to electronics, a relationship was observed between screen time and increased tension headache among children and adolescents. Objective: Elucidate the association between tension-type headache and increased screen exposure among children and adolescents. Methods: A literature review was carried out after analyzing scientific articles from 2014 to 2020, on Scielo, UPTODATE and Pubmed, in Portuguese and English. Results: With technological development and behavioural changes, the use of electronics has grown among children and adolescents. However, its overuse causes consequences such as a sedentary lifestyle, stress, reduced socialization and complaints of headache. In children, the most prevalent primary headaches are tension-type and migraine. The tension-type headache is characterized by bilateral location, in pressure, with photophobia or phonophobia, without nausea or vomiting. The hypothesis that best explains the association between tension headache and screen exposure is that consecutive periods of electronic activities cause sustained muscle tension and pain. Furthermore, there is an influence of genetic factors, diet and psychological stress. Therefore, it is necessary to raise awareness of the importance of an approach to avoid triggers for headache in children, such as controlling screen time and maintaining healthy habits. Conclusions: The correlation between excessive screen time and headache is substantial and admits an educational performance by health professionals to avoid harmful consequences to growth.

scholarly journals The relationship of Vitamin B 12 with Two Symptoms of Shingles: Who has Pain and Who has Itch?

2021 ◽  
Author(s):  
İlkay Özer ◽  
Günseli Kekeç ◽  
Duygu İlke Yıldırım ◽  
ARZU ATASEVEN ◽  
Recep Dursun
Keyword(s):  
Vitamin B12 ◽  
Negative Impact ◽  
Vitamin B12 Deficiency ◽  
Nerve Damage ◽  
Control Group ◽  
Vitamin B ◽  
Significant Difference ◽  
Patient Will ◽  
Vitamin B 12 ◽  
Pain Symptoms

Background; Both herpetic pain and itching in shingles are two symptoms whose pathogenesis has not been elucidated, although they are thought to be due to nerve damage. These two symptoms are difficult to treat and negative impact quality of life. In addition, It is unclear which patient will have the symptoms of itching or pain. Vitamin B 12 is a neurotropic agent which is contributes to the treatment of nerve damage, and effective in treating neuropathic pain and itch. In this study we investigated that is relationship between vitamin B12 both herpetic pain and herpetic itch. Methods; In this study, we investigated the effect of vitamin B12 values on itching and pain symptoms that patients with shingles have in the acute period. Vitamin B 12 values of 53 adults with patients with shingles with herpetic pain or herpetic itching were recorded and compared with the control group. Results; We found that patients with herpetic pain had lower vitamin B12 values than the control group (p=0.046) and patients with herpetic itch (p=0.021). Vitamin B12 values of herpetic itch patients did not show significant difference from the control group (p=0.816). Conclusions; Although vitamin B12 deficiency plays a role in the etiology of herpetic pain, it has no effect on herpetic itching. Our study supports that the etiopathogenesis of HI is different from herpetic pain, and will help studies focusing on herpetic itching etiopathogenesis.

Comparison of Children with Migraine and Those with Tension-Type Headache for Psychiatric Symptoms and Quality of Life

2019 ◽  
Author(s):  
Burak Sadettin Açıkel ◽  
Ayhan Bilgiç ◽  
Hatice Derin ◽  
Arzu Eroğlu ◽  
Ömer Faruk Akça ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Sleep Disturbances ◽  
Psychiatric Symptoms ◽  
Sleep Onset ◽  
Tension Type Headache ◽  
Control Group ◽  
Healthy Children ◽  
Type Headache ◽  
The Impact

AbstractThis study compared the severity of depression, anxiety, somatization, anxiety sensitivity, sleep disturbances, and quality of life (QoL) among children with migraine, children with tension-type headache (TTH), and healthy children. A total of 37 children with migraine, 22 with TTH, and a healthy control group (n = 35) participated in this study. Children with migraine exhibited higher depression and somatization and lower QoL scores than those in the control group. General sleep disturbances, bedtime resistance, sleep onset delay, sleep duration, sleep anxiety, night wakings, sleep-disordered breathing, and daytime sleepiness scores were also higher in those in the migraine group than in the control group. Regression models indicated that the severity of headache and depression scores significantly affected the QoLs of children with headache disorder as a whole. Migraine is associated with depression, somatization, sleep disturbances, and poor QoL, whereas TTH is associated with only sleep disturbances in childhood. The impact of headache on the QoL occurs mainly through the headache-specific and psychiatric factors.

Efficacy of strength training on tension-type headache: A randomised controlled study

Cephalalgia ◽  
2017 ◽  
Vol 38 (6) ◽  
pp. 1071-1080 ◽  
Author(s):  
Bjarne K Madsen ◽  
Karen Søgaard ◽  
Lars L Andersen ◽  
Birte Tornøe ◽  
Rigmor H Jensen
Keyword(s):  
Neck Pain ◽  
Strength Training ◽  
Training Group ◽  
Tension Type Headache ◽  
Controlled Study ◽  
Control Group ◽  
Significant Difference ◽  
Type Headache ◽  
Randomised Controlled

Background Strength training has shown effects in reducing neck pain. As neck pain is highly prevalent in tension-type headache (TTH), it is relevant to examine the effect of strength training of the shoulder muscles on TTH patients. Aim To examine the effect of strength training of the shoulder/neck muscles on TTH frequency and duration. Methods Sixty patients with TTH were randomised into strength training or a control group. The strength training group trained ten weeks with elastic resistance bands. The control group performed ergonomic and posture correction. Efficacy was evaluated at follow-up after 19–22 weeks. Results Twenty-three patients completed strength training and 21 completed ergonomic and posture correction (per-protocol). No between-group effect was detected, but within groups numerical reductions were noted in both groups from baseline to follow-up. Frequency of TTH in the strength training group decreased by 11% ( P = 0.041) and duration decreased by10% ( P = 0.036), while the ergonomic and posture correction group showed a significant reduction in frequency of 24% ( P = 0.0033) and a decrease in duration of 27% ( P = 0.041). Conclusion No significant difference between the groups was found and the within-group effects did not reach clinical significance. Combining all the elements into a multifaceted intervention could prove more useful and should be further explored in future studies. Clinical trials registration number NCT02984826

scholarly journals The Level of Physical Activity, Lung Function and Exercise Capacity of Children and Adolescents With Cystic Fibrosis Compared to Healthy Controls

2020 ◽  
Author(s):  
Marjane Cardoso ◽  
Caroline Jacoby Schmidt ◽  
Gabriela Motter ◽  
Gabrielle Costa Borba ◽  
Tatiana Helena Rech ◽  
...  
Keyword(s):  
Physical Activity ◽  
Cystic Fibrosis ◽  
Lung Function ◽  
Children And Adolescents ◽  
Functional Capacity ◽  
Control Group ◽  
Healthy Children ◽  
Healthy Controls ◽  
Cross Sectional ◽  
Significant Difference

Abstract Background : people with Cystic Fibrosis (CF) have progressive limitation to physical exercise and reduced daily living activities. Regular physical activity (PA) and exercise contribute to the quality of live of people with CF. The objective of this study was to evaluate level of PA , lung function and functional capacity in children and adolescents diagnosed with CF and compare them with those of healthy children and adolescents. Methodology: the study had a cross-sectional design with a control group. Patients with CF were followed at the Children’s Pneumology Outpatient Clinic, and were matched for age and sex with healthy controls from a local public school. The evaluations included daily step count, the shuttle walk test and spirometry. Results: 70 children and adolescents were evaluated, 35 diagnosed with CF and 35 healthy controls. The overall mean age was 11.6±2.9 years. There was no significant difference in level of PA between the patient and control groups. Gender analysis revealed no significant difference in level of PA between the groups or within the CF group. The CF group values were significantly lower than the control group for BMI (p=0.04), percentage of predicted FEV 1 and FEV 1 Z-score (p=0.02 and p=0.010). Conclusion: In this sample, children and adolescents with CF had the same level of PA as their healthy peers. Boys and girls with CF had similar level of PA when stratified by sex, as well as when compared to healthy peers of the same gender. Differences were observed between BMI, FEV 1 and some functional capacity test variables between the groups.

scholarly journals The Prevalence of Headache in Crohn’s Disease: Single-Center Experience

2016 ◽  
Vol 2016 ◽  
pp. 1-6
Author(s):  
Ulker Anadol Kelleci ◽  
Turan Calhan ◽  
Abdurrahman Sahin ◽  
Resul Kahraman ◽  
Kamil Ozdil ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
International Headache Society ◽  
Tension Type Headache ◽  
Control Group ◽  
Disease Group ◽  
Single Center Experience ◽  
Group 12 ◽  
Significant Difference ◽  
Type Headache

Objectives. This study is aimed at studying the prevalence and characteristics of different types of headaches in patients with Crohn’s disease.Materials and Methods. 51 patients in Crohn’s disease group (F/M: 26/25) and 51 patients in control group (F/M: 27/24) were involved. Patients in Crohn’s disease group were diagnosed and monitored according to European Crohn’s and Colitis Organization diagnostic criteria. The control group composed of healthy subjects with similar age and sex to Crohn’s disease group. Headache was classified using the International Headache Society II criteria.Results. Headache was reported by 35/51 (68.6%) patients in Crohn’s disease group and 21/51 (41.2%) patients in the control group. The prevalence of headache was statistically high in the group with Crohn’s disease (OR: 3.125 (95% CI: 1.38–7.04);p=0.01). Comparing two groups with respect to their subtypes of headaches resulted in that the tension-type headache was statistically (p=0.008) higher in Crohn’s disease group (26/51) than in the control group (12/51). However, no significant difference was found in the migraine-type headache (p=1).Conclusions. This study indicates that the prevalence of headache is high in patients with Crohn’s disease and most commonly associated with the tension-type headache.

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