Sebastiania chamaelea (L.) Mull.Arg. - Phytochemical characters

Abstract: the preliminary phytochemical screening is the foremost step to standardize a drug and also to predict its pharmacological activities. The therapeutic uses of the drug Sebastiania chamaelea (L.) Mull.Arg have been described in Hortus Malabaricus and Yogamrutham. To give a back ground to claim its therapeutic efficacy and also to validate the profile of the drug before the scientific community, the preliminary phytochemical screening of the whole plant have been done. It includes the assessment of physicochemical parameters and estimation of phytoconstituents. It has been found that the drug contains the fiber (21.08%), total sugar (4.49%), reducing sugar (3.44%), tannin (8.5%), phenol (1.36%) and pH 3.9. the qualitative analysis of the phytoconstituents showed the presence of flavonoids, saponins, carbohydrates, phenols, tannins and steroids. The presence of these pytoconstituents can be the reason behind the therapeutic efficacy of the drug Sebastiania chamaelea (L.) Mull.Arg. and thus can look forward for the pharmacological exploration of the drug.

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Phytochemical Contents, Biological Activities, and Therapeutic Applications of Hedera Helix (Ivy Leaf) Extracts: A Review

The Natural Products Journal ◽

10.2174/2210315511666210917111801 ◽

2021 ◽

Vol 11 ◽

Author(s):

Aya Shokry ◽

Riham El-Shiekh ◽

Gehan Kamel ◽

Amer Ramadan

Keyword(s):

Biological Activities ◽

Phytochemical Screening ◽

Bioactive Constituents ◽

Leaf Extracts ◽

Hedera Helix ◽

Pharmacological Activities ◽

Chemical Screening ◽

Therapeutic Uses

Background: Herbs have long been used as natural therapeutics, and recent controlled clinical studies have confirmed some of the presumed benefits. Hedera helix (ivy leaves) is a valuable common from related to the family Araliaceae. Many herbal preparations include extracts from their leaves as the principle active ingredient. Objective: The objective of this article is to summarize the pharmacological activities and phytochemical screening of H. helix. Methods: The objective of this article is to summarize the pharmacological activities and phytochemical screening of H. helix. Results: The all-published studies depend on isolation, identification and characterization of different active constituents of H. helix leaves followed by determination of biological activities in vivo and in vitro. Chemical screening has shown that H. helix leaves are a rich source of phytochemicals with demonstrated therapeutic activities, such as sterols, tannins, terpenoids, glycosides, phenols, emetine alkaloids, flavonoids, saponins, volatile and fixed oils, vitamins, carbohydrates, reducing sugars, and minerals. Further, studies of disease models and clinical trials have demonstrated anti-inflammatory, analgesic, cough suppressant, expectorant, anticancer, antimicrobial, anticoagulant, and smooth muscle relaxant activities. Conclusion: This review summarizes the bioactive constituents of H. helix leaves and their underlying pharmacological mechanisms, clinical efficacies, and safety profiles. We also suggest potential therapeutic uses for Covid-19.

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Canna indica L. (Cannaceae): A review on phytochemical, medicinal, pharmacological and biological studies

Journal of Drug Delivery and Therapeutics ◽

10.22270/jddt.v9i1-s.2363 ◽

2019 ◽

Vol 9 (1-s) ◽

pp. 520-523

Author(s):

Prashant Kumar Yadav ◽

S.S. Sisdia O

Keyword(s):

Present Article ◽

Review Article ◽

Pharmacological Profile ◽

Pharmacological Activities ◽

Canna Indica ◽

Therapeutic Uses ◽

Whole Plant ◽

Biological Studies ◽

Biological And Pharmacological Activities

This review article aims to supply in order which is necessary to assert and look at its pharmacognostic, biological and pharmacological profile. Every part of Canna has valuable properties that can serve humankind so the whole plant can be extensively studied for further research aspects. Considering the extensive uses of C. indica L. roots, leaves and rhizomes, the present article work is an attempt to explore phyto-compounds present in Canna indica L. roots leaves, and rhizomes possibly answerable for unusual pharmacological activities exhibited and thereby therapeutic uses predictable to them. This article mainly emphasized on phytoconstituents present in various parts of Canna indica L. and their corresponding biological and pharmacological activities. Keywords: Canna indica L., origin, phytoconstituents, biological and pharmacological activities

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Evaluation of cytotoxic, analgesic, antidiarrheal and phytochemical properties of Hygrophila spinosa (T. Anders) whole plant

Journal of Basic and Clinical Physiology and Pharmacology ◽

10.1515/jbcpp-2016-0103 ◽

2017 ◽

Vol 28 (2) ◽

Cited By ~ 4

Author(s):

S.M. Faysal Bellah ◽

Md. Nur Islam ◽

Md. Rezaul Karim ◽

Md. Masudur Rahaman ◽

Mst. Samima Nasrin ◽

...

Keyword(s):

Steroid Glycoside ◽

Reducing Sugar ◽

Phytochemical Screening ◽

Experimental Protocol ◽

Cytotoxic Assay ◽

Writhing Test ◽

Synthetic Drugs ◽

Analgesic Effects ◽

Whole Plant ◽

Dunnett's Test

AbstractBackground:Synthetic drugs are going to be replaced by plant-derived traditional drugs due to their cost effectiveness, relatively less harmfulness, and efficacy against multidrug resistance organisms.Methods:Preliminary phytochemical screening was accomplished by established methods modified in experimental protocol. EExHs was undertaken for cytotoxic assay by Brine shrimp lethality bioassay, antinociceptive action by acetic acid induced writhing test, and antidiarrheal activity by castor oil induced antidiarrheal test. Data were analyzed by GraphPad Prism 6.0 software using Dunnett’s test for multiple comparisons.Results:Reducing sugar, steroid, glycoside, tannin, alkaloid, saponins, and flavonoids were found to be present in EExHs. Lethal concentration (LCConclusions:This research demonstrates that the secondary metabolites guided cytotoxic and analgesic effects could be extensively studied in multiple models to confirm the effects.

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Nyctanthes Arbor-Tristis and its Role in the Alleviation of Arthritic Pain: A Review

Current Bioactive Compounds ◽

10.2174/1573407216666200109105439 ◽

2020 ◽

Vol 16 (8) ◽

pp. 1147-1156

Author(s):

Ruchi Singh ◽

Syed M. Hasan ◽

Amit Verma ◽

Sanjay K. Panda

Keyword(s):

Research Work ◽

Plant Distribution ◽

Pharmacological Activities ◽

Whole Plant ◽

Modern Drug ◽

Active Chemical ◽

Drug Synthesis ◽

New Compounds

Background: A plant is a reservoir of potentially useful active chemical entities which act as drugs as well as intermediates for the discovery of newer molecules and provide newer leads for modern drug synthesis. The demand for new compounds in the field of medicine and biotechnology is centuries old and with a rise in chronic diseases and resistance to existing drugs in the field of anti-infective agents, the chemicals obtained from plant sources have been an area of attraction. The whole plant has possessed multiple pharmacological activities. This is scientifically established by in-vivo and in-vitro studies. Methods: Various electronic databases such as PubMed, Science Direct, Scopus and Google were searched to collect the data of the present review. All the collected information is categorized into different sections as per the aim of the paper. Results: Fifty-six research and review papers have been studied and were included in this review article. After a detailed study, we provide a significant description of various phytochemicals present in Nyctanthes arbor-tristis Linn., which is responsible for various pharmacological activities. Twenty of studied articles gives a general introduction and ethnobotanical information about the plant, two papers contained microscopic detail of leaf and fruit. Twenty papers contained information about the phytoconstituents present in different parts of Nyctanthes arbor-tristis plant and fourteen articles reported pharmacological activities like antioxidant, anti-inflammatory, antiarthritic, antimicrobial and immunobiotic activity. Conclusion: This review explores the published research work comprising the ethnobotanical description of the subjected plant, distribution, phytochemical profile, and arthritis-related pharmacological activities.

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The role and uses of antibodies in COVID-19 infections: a living review

Oxford Open Immunology ◽

10.1093/oxfimm/iqab003 ◽

2021 ◽

Vol 2 (1) ◽

Author(s):

D Oliver Scourfield ◽

Sophie G Reed ◽

Max Quastel ◽

Jennifer Alderson ◽

Valentina M T Bart ◽

...

Keyword(s):

Infection Control ◽

Specific Antibody ◽

Scientific Community ◽

Vaccine Candidates ◽

Therapeutic Uses ◽

Humoral Responses

Abstract Coronavirus disease 2019 has generated a rapidly evolving field of research, with the global scientific community striving for solutions to the current pandemic. Characterizing humoral responses towards SARS-CoV-2, as well as closely related strains, will help determine whether antibodies are central to infection control, and aid the design of therapeutics and vaccine candidates. This review outlines the major aspects of SARS-CoV-2-specific antibody research to date, with a focus on the various prophylactic and therapeutic uses of antibodies to alleviate disease in addition to the potential of cross-reactive therapies and the implications of long-term immunity.

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Bagasse Wet-Stored with the Hypochlorite Bleaching Waste Water

Applied Mechanics and Materials ◽

10.4028/www.scientific.net/amm.295-298.198 ◽

2013 ◽

Vol 295-298 ◽

pp. 198-201 ◽

Cited By ~ 9

Author(s):

Bing Sun ◽

Li Bao ◽

Yu Xin Liu

Keyword(s):

Waste Water ◽

Molecular Weight ◽

Storage Time ◽

Storage System ◽

Reducing Sugar ◽

Total Sugar ◽

Small Molecular Weight ◽

Wet Storage ◽

Change Trend ◽

Better Than

In this paper, the bagasse was wet stored by hypochlorite bleaching waste water with or without chlorine. The dissolution ability of lignin, total sugar and reducing sugar was investigated. Then the effluent properties with the wet storage time prolonging were tested. The results showed that some small molecular weight substances were dissolved from baggase, such as sugar and lignin. And the dissolution ability of hypochlorite bleaching waste water with chlorine was better than that of hypochlorite bleaching waste water without chlorine. And the change trend of effluent properties for the two wet storage system were similar. With the wet storage time extending, the dissolved substances were degraded, COD and chroma of effluent were decreased, and the properties of effluent were improved.

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Morpho-Biochemical Characteristics of Brinjal Germplasms Affect the Abundance And Infestation of Jassid

SAARC Journal of Agriculture ◽

10.3329/sja.v19i1.54780 ◽

2021 ◽

Vol 19 (1) ◽

pp. 81-91

Author(s):

F Yasmin ◽

MR Amin ◽

M Afroz ◽

MAH Swapon ◽

MM Hossain

Keyword(s):

Protein Content ◽

Chlorophyll Content ◽

Negative Correlation ◽

Significant Positive Correlation ◽

Significant Negative Correlation ◽

Reducing Sugar ◽

Total Sugar ◽

The Other ◽

Biochemical Characteristics ◽

Positive Correlation

The tropical vegetable, brinjal is cultivated throughout the year in Bangladesh but the crop is infested by a number of insects including jassid. This study investigated the effects of different biophysical and biochemical characteristics of twelve brinjal germplasms on the abundance and infestation of jassid. The experiment was conducted during September 2018 to March 2019 in Gazipur, Bangladesh with twelve brinjal germplasms namely BD-7320, BD-7328, BD-9952, BD-10154, BD-10158, BARI Begun-1, BARI Begun-4, BARI Begun-5, BARI Begun- 6, BARI Begun-7, BARI Begun-8 and BARI Begun-9. The incidence of jassid was recorded from 3rd December to 26th March, and the lowest population was found on BARI Begun- 6. Among the biophysical traits, plant height, number of branch and leaf per plant, and leaf area exerted significant positive correlation; whereas trichome on lower and upper surfaces of leaf, spine per stem and leaf showed significant negative correlation with the abundance of jassid. On the other hand, moisture, reducing sugar, total sugar and protein content of the leaves and fruits, chlorophyll content of the leaves exerts significant positive correlation but ash and pH contents of the leaves and fruits were negatively correlated with the abundance of jassid. Jassids showed the lowest level of leaf infestation on BARI Begun-6, which could be for further analysis to develop jassid resistant brinjal. SAARC J. Agric., 19(1): 81-91 (2021)

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Modification process in nixtamalization of folic acid-rich dent corn (Zea mays identata) and its identification as smart food fortificant

MATEC Web of Conferences ◽

10.1051/matecconf/201815401017 ◽

2018 ◽

Vol 154 ◽

pp. 01017 ◽

Cited By ~ 10

Author(s):

Agustine Susilowati ◽

Puspa Dewi Lotulung ◽

Yati Maryati ◽

Aspiyanto

Keyword(s):

Zea Mays ◽

Folic Acid ◽

Glutamic Acid ◽

Relative Intensity ◽

Reducing Sugar ◽

Total Sugar ◽

Initial Material ◽

Operation Condition ◽

Modification Process ◽

Dent Corn

A modification on nixtamalization process of dent corn (Zea mays identata) was conducted in order to recover natural folic acid-rich corn. Nixtamalization process on varieties of white dent corn and yellow dent corn subsequently were performed by steeping solution of Ca(OH)2 at concentrations of 0, 10, 20 and 30 % (w/w corn dissolved protein) for 18 hours, and boiling at 90 °C for 15, 30, 45 and 60 minutes. Result of research showed that concentration of Ca(OH)2 solution becoming more and more high and long boiling time increased both folic acid and reducing sugar, dropped total solids and total sugar, and fluctuated dissolved protein for both types of corn. Nixtamalization optimalization of white dent corn and yellow dent corn were achieved at combination of Ca(OH)2 20 % (w/w corn dissolved protein) for 60 minutes of boiling and Ca(OH)2 30 % for 30 minutes of boiling and gave folic acid of 466.81 and 506.74 μg/mL, respectively. In this condition, it is occurred an increase of folic acid 192.3 % (1.9 folds) and 139.89 % (1.4 folds) when compared to initial material of corn. Identification on folic acid monomer and glutamic acid monomer of both nixtamalized dent corn and yellow dent corn at optimum operation condition displayed domination of folic acid monomer with molecular weight (MW) 442.56 Dalton (Da.) with relative intensity 25.51 %, and 441.73 Da. with relative intensity 100 %, while glutamic acid monomer of nixtamalized yellow dent corn and nixtamalized white dent corn were dominated by monomer with MWs of 148.27 Da. and 148.32 Da., and relative intensity 3.73 and 1.8 %.

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TERMINALIA CHEBULA: SUCCESS FROM BOTANY TO ALLOPATHIC AND AYURVEDIC PHARMACY

Asian Journal of Pharmaceutical and Clinical Research ◽

10.22159/ajpcr.2016.v9i5.13074 ◽

2016 ◽

Vol 9 (5) ◽

pp. 21

Author(s):

Varun Garg ◽

Barinder Kaur ◽

Sachin Kumar Singh ◽

Bimlesh Kumar

Keyword(s):

Chemical Constituents ◽

Present Review ◽

Terminalia Chebula ◽

Pharmacological Activities ◽

Therapeutic Uses ◽

Anti Cancer ◽

Anti Oxidant ◽

Anti Inflammatory

ABSTRACTTerminalia chebula (TC) is a unique herb having various therapeutic potentials as anti-inflammatory, antioxidant, anticancer, and digestant. It belongsto family Combretaceae. In the present review, an attempt has been made to decipher classification, chemical constituents, therapeutic uses, andpatents that have been reported for TC. Various pharmacological activities of TC that make it as potential medicine and its Ayurvedic formulationsare highlighted.Keywords: Terminalia chebula, Anti-oxidant, Anti-cancer, Ayurvedic formulations, Anti-oxidant.

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