Therapeutic uses of Vilwa (Aegle marmelos) in Ayurveda with Pharmacological Evidence

2021 ◽  
pp. 51-54
Author(s):  
Purnendu Panda ◽  
Banamali Das ◽  
G.C. Bhuyan ◽  
M.M. Rao
Keyword(s):  
Indian Subcontinent ◽  
Folk Medicine ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Therapeutic Effects ◽  
Gi Tract ◽  
Aegle Marmelos ◽  
Traditional System ◽  
Therapeutic Uses ◽  
Irritable Bowel

Aegle marmelos, a plant indigenous to India has been used by the inhabitants of the Indian subcontinent for over 5000 years. The leaves, bark, roots, fruits and seeds are used extensively in the Indian traditional system of medicine the Ayurveda and in various folk medicine to treat myriad ailments. It possesses broad range of therapeutic effects that includes free radical scavenging, antioxidant, inhibition of lipid peroxidation, antibacterial, antiviral, anti-diarrheal, gastroprotective, antiulcerative colitis, hepatoprotective, anti-diabetic, cardioprotective and radioprotective effects.In Ayurveda it has been used for the treatment of Atisara (loose stool), Pravahika (dysentery), Shoth (generalised or localised swelling), Gulma (localised gas in abdominal region), Arsha ( haemorrhoids), Grahani (irritable bowel syndrome), Pandu (anaemia), Shvasa (respiratory disorders), Hikka (hiccough), Kasa (cough), Parshwashula (pain in chest bilaterally), Hritshula (cardiac problems), Udararoga (disorders of GI tract), Halimaka (a type of jaundice), Vataroga (nervine disorder).

Antioxidant Activities of Yinchenhao (Artemisiae Capillaris) Leaves

2020 ◽  
Vol 18 (4) ◽  
pp. 386-391
Author(s):  
Yonghun Kim ◽  
Ang Li ◽  
Junyu Wang ◽  
Wancong Yu ◽  
Fang Wan ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Free Radical ◽  
Ethyl Acetate ◽  
Antioxidant Activities ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Free Radical Scavenging Activity ◽  
Therapeutic Effects ◽  
Scavenging Activity

Yinchenhao (Artemisia capillaris Thunb.) is a pharmaceutical agent that not only shows therapeutic effects against hepatobiliary diseases but also offers various physiological benefits. This study examined the extraction rates of antioxidant extracts from Yinchenhao leaves using different solvents. The extraction rates using different solvents were as follows: ethanol (12.1 ± 0.87%) > water (7.7 ± 0.45%) > n-butanol (1.3 ± 0.16%) ethyl acetate > (1.3 ± 0.14%) > n-hexane (1.1 ± 0.15%). The n-butanol and ethyl acetate extracts showed higher 1,1-Diphenyl-2 picrylhydrazyl radical free radical scavenging activity, 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulphonate) free radical scavenging activity and ferric ion reducing antioxidant activity, while n-hexane extracts showed weak antioxidant activity. In conclusion, Yinchenhao leaf has potential as a natural antioxidant, and n-butanol and ethyl acetate may be effective extraction solvents for studying its antioxidant activities.

scholarly journals A Review of the Pharmacological Effects of the Dried Root ofPolygonum cuspidatum(Hu Zhang) and Its Constituents

2013 ◽  
Vol 2013 ◽  
pp. 1-13 ◽  
Author(s):  
Huan Zhang ◽  
Chang Li ◽  
Sin-Tung Kwok ◽  
Qing-Wen Zhang ◽  
Shun-Wan Chan
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Folk Medicine ◽  
Therapeutic Effects ◽  
Pharmacological Effects ◽  
Polygonum Cuspidatum ◽  
Republic Of China ◽  
Therapeutic Uses ◽  
Snake Bites ◽  
The World

Traditional Chinese medicine (TCM) has been widely used in China for thousands of years to treat and prevent diseases. TCM has been proven safe and effective, and it is being considered as one of the important types of complementary and alternative medicine and receives increasing attention worldwide. The dried root ofPolygonum cuspidatumSieb. et Zucc. (also known as “Hu Zhang” in Chinese) is one of the medicinal herbs listed in the Pharmacopoeia of the People's Republic of China. Hu Zhang is widely distributed in the world. It can be found in Asia and North America and is used as folk medicine in countries such as Japan and Korea. In China, Hu Zhang is usually used in combination with other TCM herbs. The therapeutic uses of those Hu Zhang-containing TCM prescriptions or formulations are for treating cough, hepatitis, jaundice, amenorrhea, leucorrhea, arthralgia, burns and snake bites. Recent pharmacological and clinical studies have indicated that Hu Zhang has antiviral, antimicrobial, anti-inflammatory, neuroprotective, and cardioprotective functions. This review gives a summary of the reported therapeutic effects of the active compounds and the different extracts of Hu Zhang.

scholarly journals Antioxidative and Free Radical Scavenging Activities of Some Plants Used in Thai Folk Medicine

2006 ◽  
Vol 44 (3) ◽  
pp. 221-228 ◽  
Author(s):  
N. Hutadilok-Towatana ◽  
P. Chaiyamutti ◽  
K. Panthong ◽  
W. Mahabusarakam ◽  
V. Rukachaisirikul
Keyword(s):  
Free Radical ◽  
Folk Medicine ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Free Radical Scavenging Activities

scholarly journals Knowledge, Practice And Use Of Aegle Marmelos (L.) Correa Leaves Among Naturopathy And Ayurvedic Practitioners Of Vadodara City and Desk Review On Various Commercial Formulations available In Health And Disease Specially Diabetes

2017 ◽  
Vol 9 (3) ◽  
pp. 451
Author(s):  
Vinita Gopalchandra Nigam ◽  
Vanisha S. Nambiar
Keyword(s):  
Folk Medicine ◽  
Sampling Technique ◽  
Aegle Marmelos ◽  
Gujarat State ◽  
Traditional System ◽  
Share Data ◽  
Leaf Powder ◽  
Health And Disease ◽  
Knowledge Practice ◽  
Treatment Of Diabetes

<p>The <em>Aegle marmelos (L.) Correa</em> (Bael), is  indigenous to India and its leaves, bark, roots and fruit have  been used for over 5000 years in the Indian traditional system of medicine like the Ayurveda, Naturopathy  and in various folk medicine to treat various diseases including diabetes. This study was conducted to assess Knowledge, Practice and Use (KPU)of <em>Aegle Marmelos (L.) Correa</em> leaves among 20 Ayurvedic (AP) and Naturopathic practitioners (NP) in Vadodara city as well as desk reviews on various commercial formulations of <em>Aegle Marmelos (L.) Correa</em> (Bael) used in health and disease specially diabetes using internet</p><p>Desk reviews were done using Pub Med and other web sources along with personal visits to various libraries across Gujarat state. For KPU, Purposive selection of AP (n=10) and NP (n=10) was done using snow ball sampling technique from Vadodara city in the form of key informant interviews based on their oral consent to share data among.</p><p>Desk reviews revealed that <em>Aegle Marmelos (L.) Correa </em>leaves were being recognized as a remedy for the treatment of diabetes in both Ayurveda and Naturopathy. Many Ayurvedic formulations were available commercially as poly herbal formulations (PHF) rather than single drug in the market of various reputed brands which contained <em>Aegle Marmelos (L.) Correa </em>leaves in the form of various powder, tablets, capsules, etc.  Naturopathy did not contain any commercial brands of <em>Aegle Marmelos (L.) Correa </em> leaves as it believes in fresh doses of the plant.</p><p>KPU results revealed that AP used bael leaves for the treatment of diabetes and the dosage for the treatment ranged from 5-10g/day in various forms such as powder, decoction and dry extract in the form of capsules (1 capsule contains 0.5mg of extract which is equivalent to 5mg of leaf powder). NP<strong> </strong>also used<strong> </strong>bael<em> </em>leaves for the treatment of diabetes and the dosage ranged from 40-50 fresh leaves in the form of juice mixed with water to make a volume of around 100ml.</p><p>Bael<em> </em>leaves were reported to be used by these practitioners as anti-diabetic agent. This information extracted warrants further clinical trials to prove the efficacy of the anti-diabetic properties of these leaves.</p>

scholarly journals Synthesis of Silver Nanoparticles Using Flavonoid Hesperidin and Pharmacological Evaluation of its Free Radical Scavenging Activity

2022 ◽  
Vol 8 (1) ◽  
pp. 192-199
Author(s):  
Mahesh Kumar D
Keyword(s):  
Silver Nanoparticles ◽  
Free Radical ◽  
Radical Scavenging Activity ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
The Body ◽  
Free Radical Scavenging Activity ◽  
Therapeutic Effects ◽  
Scavenging Activity ◽  
Wide Range

Background: Silver Nanoparticles are drawing significant attention from the scientific community to explore a wide range of its medical applications. Human body is under constant stress due to free radicals generated by the physiological and pathological conditions in the body. Scavenging systems or Antioxidants can help alleviate the damages caused by these radicals which can influence the course of progress in several chronic diseases with an inflammatory background. External antioxidants supplement and facilitate the overwhelmed scavenging systems in the body.Silver Nanoparticles can enhance the therapeutic effects of phytochemicals. Aim: To Synthesize silver nanoparticles using the phytochemical Hesperidin and studying its Free radical scavenging activity. Methods: Silver Nanoparticles are synthesized using chemical reduction method. The synthesis is confirmed using spectrophotometric studies. Free Radical scavenging activity is detected using 1, 1-diphenyl-2-picrylhydrazyl (DPPH •) free radical scavenging assay. Results: Silver nanoparticles were successfully synthesized which was confirmed by the change in color of the solution and peak absorbance peak at 420 nM on spectrophotometric studies.Hesperidin Silver Nanoparticles exhibited higher free radical scavenging activity when compared with pure hesperidin and standard Ascorbic acid. Conclusion: Hesperidin can ideally be used for the synthesis of silver nanoparticles and the synthesized Silver Nanoparticles enhances the free radical scavenging activity of Hesperidin which can further be evaluated by In Vivo studies.

Active Metabolites from Dunalia spinosa Resinous Exudates

2008 ◽  
Vol 63 (7-8) ◽  
pp. 492-496 ◽  
Author(s):  
Silvia Erazo ◽  
Giovanna Rocco ◽  
Mercedes Zaldivar ◽  
Carla Delporte ◽  
Nadine Backhouse ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Radical Scavenging Activity ◽  
Folk Medicine ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Withaferin A ◽  
Scavenging Activity ◽  
Active Metabolites ◽  
Aerial Parts ◽  
Strong Antimicrobial Activity

Dunalia spinosa, a plant used in folk medicine for toothaches, breathing problems and cleansing wounds, was found active as antimicrobial and antioxidant. A new (E)-aurone rutinoside (dunaurone) has been isolated from the aerial parts of the plant, and its structure was determined by spectroscopic means. Lupeol, ß-sitosterol, scopoletin, quercetin and withaferin A were also found. All the extracts exhibited strong antimicrobial activity while dunaurone showed only weak antimicrobial inhibition against Klebsiella pneumoniae; in addition it presented a significant free radical scavenging activity.

scholarly journals Antioxidative Activity and Phenols Content in Five Tropical Lamiaceae Plants

2013 ◽  
Vol 1 (2) ◽  
pp. 49-54
Author(s):  
M.S. Azman Abdul Rahim ◽  
Jailani Salihon ◽  
Mashitah Mohd Yusoff ◽  
M. Rizal Martua Damanik
Keyword(s):  
Antioxidant Activity ◽  
Functional Food ◽  
Antioxidative Activity ◽  
Folk Medicine ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Total Phenols ◽  
Freeze Dried ◽  
Pogostemon Cablin ◽  
Free Radical Scavenging Assay

The total antioxidants content in five Lamiaceae plants were examined. Fresh Plecranthus amboinicus Lour. Indonesia leaves were collected from Jakarta, Indonesia and leaves of Plecranthus amboinicus Lour. Malaysia, Pogostemon cablin Benth., Solenostemon scutellariodes Red and Solenostemon scutellariodes Mix Colour were collected from Kuantan, Malaysia. Leaves were freeze-dried, ground and extracted using methanol. The extracted leaves were determined the scavenging activity of the stable 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging assay. Results showed that the P. cablin Benth. leaves exhibited the significant (p<0.05) highest degree of antioxidant activity (63.18%). It was followed by S. scutellariodes Red (54.81%) and S. scutellariodes Mix Colour (50.44%) which both showed significant differences (p<0.05). Both of the P. amboinicus Lour. Malaysia and P. amboinicus Lour. Indonesia displayed the lowest degree of antioxidant activity (p>0.05), i.e 47.07% and 45.38%, respectively. The P. cablin Benth. showed the total phenols (7.64 mg/g fw) but insignificant with the P. amboinicus Lour. Indonesia (7.42 mg/g fw), S. scutellariodes Red (7.32 mg/g fw) and P. amboinicus Lour. Malaysia (7.23 mg/g fw). Only the S. scutellariodes Mix Colour showed significantly (p?0.05) compared total phenols (5.64 mg/g fw). This research provided a chemical basis for some of the health benefits claimed for in folk medicine and warrant further studies to develop it as a natural functional food.

scholarly journals The hepatoprotective effect of Arnebia euchroma hydro-alcoholic extract against liver toxicity induced by CCl4 in mice

2018 ◽  
Author(s):  
Mohammad Shokrzadeh ◽  
Mohammad Azadbakht ◽  
Hamidreza Shakibamanesh
Keyword(s):  
Antioxidant Activity ◽  
Free Radical ◽  
Radical Scavenging ◽  
Free Radical Scavenging ◽  
Hepatoprotective Effect ◽  
Total Phenolic ◽  
Therapeutic Effects ◽  
Alcoholic Extract ◽  
Hydroalcoholic Extract ◽  
Arnebia Euchroma

Arnebia euchroma is from Boraginaceae family. Various therapeutic effects have been reported for different species of this plant. The aim of this study was to investigate antioxidant activity of hydroalcoholic extract of the root of A. euchroma and its protective effect on hepatotoxicity induced by CCl4 in mice. In this experimental study, A. euchroma was extracted with ethanol solvent by maceration method. Antioxidant activity of the plant has been evaluated by the DPPH free radical scavenging method. Then, the hepatoprotective effect of A. euchroma was evaluated through determination the content of glutathione in liver tissue, ALP, AST, ALT serum levels and histopathology of liver in different groups. The total phenolic content determined as 0.56% per 100 g of plant was equivalent to gallic acid. The total flavonoid content was 0.079% per 100 g of plant that was equivalent to quercetin. The IC50 of the extract for free radical scavenging was obtained 139.2 μg/ml. The extract increased liver glutathione and serums ALP, AST, ALT that were decreased by CCl4 administration in animal. All protective effects were dose-dependent and the results of liver histopathology showed a significant improvement of inflammation and necrosis that were caused by CCl4 in mice. The results of this study revealed that the hydroalcoholic extract of A. euchroma root has an antioxidant effect and excellent hepatoprotection in mice.

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