Risk factors for screw migration after triple pelvic osteotomy

2001 ◽  
Vol 37 (3) ◽  
pp. 269-273 ◽  
Author(s):  
S Simmons ◽  
AL Johnson ◽  
DJ Schaeffer

The objective of this retrospective study was to identify risk factors for screw migration after triple pelvic osteotomy (TPO) in clinical patients. The medical records, radiographs made immediately after surgery, and follow-up radiographs documenting a healed osteotomy were reviewed for 52 dogs treated with unilateral TPO and 38 dogs treated with bilateral TPO. Signalment, surgeon expertise, length of surgery, sequence of surgery in dogs treated bilaterally, use of ischial or ilial wires or both, screw depth in the sacrum, and screw migration were documented for each of the 128 pelvic osteotomies. Screws placed in the first and second plate hole, securing the cranial portion of the plate, loosened most frequently. Factors associated with decreased screw migration included use of an ischial hemicerclage wire and increased depth of sacral purchase with the first and second cranial screws.

2020 ◽  
Vol 14 (Supplement_1) ◽  
pp. S207-S208
Author(s):  
V Domislović ◽  
I Knežević-Štromar ◽  
M Premužić ◽  
M Brinar ◽  
D Vranešić Bender ◽  
...  

Abstract Background Patients with IBD are at higher risk for non-alcoholic fatty liver disease (NAFLD) comparing to general population. Complex pathogenesis of NAFLD in IBD may be related to disease-specific risk factors such as chronic inflammation, steroid exposure, drug induced hepatotoxicity, malnutrition and alteration of gut microbiota, which is emerging as a major factor in the pathogenesis of NAFLD. The goal of the study was to investigate factors associated with NADLF and advanced liver fibrosis (ALF) in patients with CD and UC. Methods This is a retrospective study on IBD patients without extraintestinal manifestations and known liver disease. NAFLD was defined as Hepatic Steatosis Index (HSI) ≥ 36, and ALF was defined as FIB-4 ≥ 2.67. Predictors of NAFLD development were analysed using Kaplan–Meier and Cox regression analyses. Results In this retrospective study, we have included 225 IBD patients; 72.4% (n = 163) patients with CD and 27.6% (n = 62) patients with UC (median age 41.2 yr, 53.7% males) which were observed for a median of 4.6 years. There were 63.1% (n = 142) patients with normal BMI, 27.6% (n = 62) overweight and 9.3% (n = 21) obese patients. Obese patients had the highest HIS score 43.9 ± 5.9, following with overweight 37.8 ± 5.7 and normal BMI 30 ± 4.3 kg/m2, p < 0.001. During the follow-up obese and overweight patients had higher risk of developing NAFLD comparing to patients with normal BMI (obese HR = 11.1 95% CI 4.3–28.3 and overweight HR = 5.55 95% CI 3.4–9.1, Logrank test p < 0.001) (Figure 1). Regarding FIB-4 score there, was no difference among different BMI categories (p = 0.192), and there was no difference in ALF development in the follow-up period (Logrank test p = 0.91). In Cox proportional-hazards regression significant predictors for NAFLD development were dyslipidaemia HR=2.11, 95% CI 1.2–3.7, overweight HR=6 95% CI 3.6–10, and obesity HR=13.4, 95% CI 7–35. Conclusion NAFLD is frequent comorbidity in patients with CD and UC, which can lead to development of advanced liver fibrosis. Our results show that patients with IBD have a high risk of NAFLD development, whereas the increased risk for ALF was not observed. Overweight and obese patients and those with dyslipidemia should be closer monitored due to significantly higher risk of NAFLD. This study points out the complexity disease-specific risk factors and importance of better stratifying IBD patients at risk of NAFLD and advanced liver fibrosis.


2017 ◽  
Vol 4 (suppl_1) ◽  
pp. S42-S42
Author(s):  
Amrita Bhardwaj ◽  
Maroun Mhanna ◽  
Nazha Abughali

Abstract Background Lack of adequate testing and follow-up in infants born to hepatitis C virus (HCV) infected mothers continue to be a major challenge. There are multiple risk factors associated with this low rate of testing and follow-up including maternal, healthcare-related, and social factors. We sought to identify maternal risk factors that are associated with low HCV testing and follow-up in perinatally exposed infants. Methods In a retrospective cohort study, all HCV-infected pregnant women and their infants were reviewed. The study period expanded from June 1993 to May 2016. Medical records were reviewed for maternal characteristics and risk factors that could be associated with inadequate testing and loss to follow-up in infants with perinatal HCV exposure. Results During the study period, medical records of 407 mothers and their infants were reviewed. Only 26.5% (108/407) of all infants had adequate testing and follow-up for HCV. Among all infants, history of maternal intravenous drug use (IVDU) was significantly higher in infants with inadequate HCV testing than infants who were adequately tested [88% (193/218) vs. 76% (70/92) respectively; P = 0.005]. Infants who were adequately tested for HCV had a higher percentage of mothers on methadone maintenance therapy during pregnancy than infants who were not adequately tested [53% (35/66) vs. 34% (65/186) respectively; P = 0.010]. Also, infants with mothers who had HCV care were more likely to be adequately tested than infants whose mothers did not have HCV care [54% (56/102) vs. 41% (106/255), respectively; P = 0.022]. HCV transmission rate among infants with adequate testing was 11.1% (12/108). Conclusion Infants born to HCV infected mothers continue to have suboptimal testing. Maternal history of IVDU is associated with inadequate testing and loss to follow-up among infants exposed perinatally to HCV. Whereas, maternal methadone maintenance therapy during pregnancy, and maternal HCV medical care are associated with better follow-up. Screening pregnant women with HCV infection for history of IVDU and linking them to drug treatment centers as well as to HCV medical care may improve testing and follow-up in infants with perinatal HCV exposure. Disclosures All authors: No reported disclosures.


2021 ◽  
Author(s):  
yongjun li ◽  
xing wei ◽  
Bingyao Chen ◽  
feng wang ◽  
Guangze Song ◽  
...  

Abstract Study Design: A retrospective study.Objective: The purpose of this study was to clarify the risk factors associated with dysphagia following anterior surgery treating multilevel cervical disorder with kyphosis based on subgroup of follow-up time.Methods: Totally, 81 patients who suffered from multilevel cervical disorder with kyphosis receiving anterior surgery from July 2018 to June 2020 were reviewed for clinical and radiological outcomes. Patients with dysphagia was defined as dysphagia group and without dysphagia as no-dysphagia group according to follow-up time (1 week, 1-month, 3-month, 6-month and 1-year after surgery). Data was performed to compare between the patients with and without dysphagia.Results: In our study, the occurrence of dysphagia was 67.9%, 44.4%, 34.6%,25.9% and 14.8% at the time of 1 week, 1-month, 3-month, 6-month, and 1 -year after surgery, respectively. Our findings showed that a history of smoking, lower preoperative Swallowing Quality of Life (SWAL-QOL) score, post-operative Cobb angle of C2-7 and change of Cobb angle of C2-7 were associated with dysphagia within 3-month after surgery. Furthermore, a history of smoking, lower preoperative SWAL-QOL score, and post-operative Cobb angle of C2-7 were linked with dysphagia within 6-month after surgery. However, a history of smoking and lower preoperative SWAL-QOL score were found to be risk factors related with dysphagia at at any follow-up.Conclusions: In the present study, many factors were related with dysphagia during 3-month after surgery. What’s more, a history of smoking and lower preoperative SWAL-QOL score were associated with dysphagia at any follow-up. We hope this article can provide a reference for spinal surgeons to predict which patients were susceptible to suffer from dysphagia after anterior surgery in treatment of multilevel cervical disorder with kyphosis.


2021 ◽  
Author(s):  
Vicente Abril ◽  
Neus Gómez ◽  
Hilary Piedrahita ◽  
Mercedes Chanzá ◽  
Nuria Tormo ◽  
...  

Abstract BackgroundCoinfections in COVID19 appear to worsen hospitalized patients prognosis.ObjectiveTo describe the characteristics of bacterial and fungal coinfections in patients admitted for COVID19 and to identify the risk factors associated with its occurrence.Patients and MethodsSingle-center retrospective study reviewing medical records of patients with COVID19 diagnosed with bacterial or fungal infection during hospital admission.Results333 patients were analyzed during March 15-May 15, 2020. 16.82% had some coinfection during admission. Coinfections were more frequent in patients with comorbidities (80.36% vs 19.64% p<0.025) and in those ICU admitted (52.46% vs 8.86%, p<0.001). Coinfections were significantly more frequent in patients with neutrophilia>7500 and increased procalcitonin on admission as well as lymphopenia<1500 on day 5. Mortality in patients with coinfection was 26.79% vs 23.47% in non-coinfected (p 0.596). Length of stay was longer in coinfected patients (mean 30.59 vs 13.47, p<0.01). Most frequent microorganisms were Enterococci, Candida spp, Enterobacteriaceae and Pseudomonas spp. 74% of patients received ceftriaxone: 17.34% of those treated had a coinfection compared to 15.48% not treated (p 0.694).ConclusionsOccurrence of coinfections is frequent and prolongs hospital stay without influencing mortality. The presence of comorbidities and ICU stay were identified as the main risk factor for coinfection, while increased neutrophils and procalcitonin at admission and lymphopenia during evolution were the main biological predictors. Enterococcus was the most frequent pathogen. Ceftriaxone use does not protect against appearance of bacterial infections. C. albicans was the most frequently isolated fungus and was associated with prolonged ICU stay.


2015 ◽  
Vol 2 (1) ◽  
pp. 34
Author(s):  
Retno Asih

Background: Pneumonia is known as a frequent cause of morbidity and mortality among children in developing countries. In children,it caused predominantly by bacteria. Bacteremia has been associated with severity and mortalitas of pneumonia. Identify factors caused bacteremia important to prevent severity and mortalitas of pneumonia. Objective: The objective of this study was to identify risk factors of bacteremia in children with pneumonia. Methods: A retrospective study was conducted in children with pneumonia in Dr. Soetomo Surabaya Hospital from January 2007 to December 2008. Blood cultures be performed on all of this patients. Factors associated with bacteremia were identified following review of medical records include clinical features, laboratory , radiology and blood culture results. Results: Frequency of bacteremia was 8,2% (36 patients) of 438 children with pneumonia. Interval from onset of symptoms to hospital admission more than 5 days (22.69 CI 95%), severe malnourished (OR 9.05 CI 95%), anemia (OR 2.44 CI 95%), leucocyt counts less than 5000/mm3 and more than 20.000/mm3 (OR 2.41 CI 95%) and paO2 less than 80 mmHg (OR 4.25 CI 95%) were at increased risk of bacteremia in children with pneumonia. Conclusion: Risk factors bacteremia in children with pneumonia included age under 1 year, symptoms more than 5 days, severe malnourished ,anemia, leucosyt counts less than 5000/mmand more than 20.000/mm3 and paO2 less than 80 mmHg.


2021 ◽  
Author(s):  
Shize Jiang ◽  
Liqing Lang ◽  
Bing Sun ◽  
Dongyan Wu ◽  
Rui Feng ◽  
...  

Abstract PurposeTo evaluate the risk factors associated with motor deficit following surgeries involving rolandic & peri-rolandic cortex and to introduce our surgical experiences dealing with lesions in this region.MethodsWe retrospectively reviewed patients who experienced drug-refractory epilepsies and received surgeries in our hospital. Medical records were carefully studied, and patients with lesions located in the rolandic & peri-rolandic cortex were screened. Those with detailed follow-up information were included. Lesion locations, resected regions, and invasive exploration techniques were studied to assess their relationship with the postoperative motor deficit.ResultsA total of 41 patients with lesions located in the rolandic or peri-rolandic cortex were included in this study. Of all these patients, 23 (56.10%) patients suffered from a transient motor deficit and 2 (4.88%) with a permanent disability after surgery. All eight patients with the anterior bank of precentral sulcus resected experienced motor deficit, and six of them gradually recovered within half a year. Seven patients with the anterior half of precentral gyrus resected did not experience permanent disability. A total of 14 (34.15%) patients received invasive exploration, and one of them had a permanent disability.ConclusionsThe anterior bank of the central sulcus is indispensable for motor functions, and the destruction of this region would inevitably cause a motor deficit. The upper part of the central sulcus could also be removed without significant neurological impairment if there is an epileptogenic lesion.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Negeso Gebeyehu Gejo ◽  
Melaku Tesfaye W/mariam ◽  
Biruk Assefa Kebede ◽  
Ritbano Ahmed Abdo ◽  
Abebe Alemu Anshebo ◽  
...  

Abstract Background Preterm birth is defined as the birth of a baby before 37 completed weeks of gestation. Worldwide, prematurity is the second foremost cause of death in children under the age of 5 years. Preterm birth also gives rise to short and long term complications. Therefore, the primary aim of this study was to identify the factors associated with preterm birth in Wachemo University Nigist Eleni Mohammed Memorial referral hospital, Hadiya Zone, Southern Ethiopia. Methods An institution-based unmatched case-control study was conducted from July 01, 2018 to June 30, 2019 among mothers who gave birth in Wachemo University Nigest Eleni Mohammed Memorial referral hospital. A retrospective one-year data was retrieved from medical records of mothers with their index neonates. Simple random sampling technique was employed to recruit study participants. SPSS version 20 software was used for data entry and computing statistical analysis. Both bivariable and multivariable logistic regression analyses were used to determine the association of each independent variable with the dependent variable. Odds ratio with their 95% confidence intervals was computed to identify the presence and strength of association, and statistical significance was affirmed if p < 0.05. Result The current study evaluated 213 medical records of mothers with index neonates (71 cases and 142 controls). Urban residency [AOR = 0.48; 95% Cl; 0.239, 0.962], antenatal care follow up [AOR = 0.08; 95 Cl; 0.008, 0.694], premature rupture of membranes [AOR = 3.78; 95% Cl; 1.467, 9.749], pregnancy induced hypertension [AOR = 3.77; 95% Cl; 1.408, 10.147] and multiple pregnancies [AOR = 5.53; 95% Cl; 2.467, 12.412] were the factors associated with preterm birth. More than one-third (36.6%) preterm neonates died in the present study. Conclusions The present study found that urban residency, antenatal care follow up, premature rupture of membranes, pregnancy induced hypertension and multiple pregnancies were factors associated with preterm birth. The mortality among preterm neonates is high. Enhancing antenatal care follow up and early detection and treatment of disorders among pregnant women during antenatal care and undertaking every effort to improve outcomes of preterm birth and reduce neonatal mortality associated with prematurity is decisive.


2021 ◽  
pp. 000348942110155
Author(s):  
Leonard Haller ◽  
Khush Mehul Kharidia ◽  
Caitlin Bertelsen ◽  
Jeffrey Wang ◽  
Karla O’Dell

Objective: We sought to identify risk factors associated with long-term dysphagia, characterize changes in dysphagia over time, and evaluate the incidence of otolaryngology referrals for patients with long-term dysphagia following anterior cervical discectomy with fusion (ACDF). Methods: About 56 patients who underwent ACDF between May 2017 to February 2019 were included in the study. All patients were assessed for dysphagia using the Eating Assessment Tool (EAT-10) survey preoperatively and late postoperatively (≥1 year). Additionally, 28 patients were assessed for dysphagia early postoperatively (2 weeks—3 months). Demographic data, medical comorbidities, intraoperative details, and post-operative otolaryngology referral rates were collected from electronic medical records. Results: Of the 56 patients enrolled, 21 patients (38%) had EAT-10 scores of 3 or more at long-term follow-up. None of the demographics, comorbidities, or surgical factors assessed were associated with long-term dysphagia. Patients who reported no long-term dysphagia had a mean EAT-10 score of 6.9 early postoperatively, while patients with long-term symptoms had a mean score of 18.1 ( P = .006). Of the 21 patients who reported persistent dysphagia symptoms, 3 (14%) received dysphagia testing or otolaryngology referrals post-operatively. Conclusion: Dysphagia is a notable side effect of ACDF surgery, but there are no significant demographics, comorbidities, or surgical risk factors that predict long-term dysphagia. Early postoperative characterization of dysphagia using the EAT-10 questionnaire can help predict long-term symptoms. There is inadequate screening and otolaryngology follow-up for patients with post-ACDF dysphagia.


2021 ◽  
Vol 10 (5) ◽  
pp. 928
Author(s):  
Takuya Okugawa ◽  
Tadayuki Oshima ◽  
Keisuke Nakai ◽  
Hirotsugu Eda ◽  
Akio Tamura ◽  
...  

Background: The frequency of delayed bleeding after colorectal polypectomy has been reported as 0.6–2.8%. With the increasing performance of polypectomy under continuous use of antithrombotic agents, care is required regarding delayed post-polypectomy bleeding (DPPB). Better instruction to educate endoscopists is therefore needed. We aimed to evaluate the effect of instruction and factors associated with delayed bleeding after endoscopic colorectal polyp resection. Methods: This single-center, retrospective study was performed to assess instruction in checking complete hemostasis and risk factors for onset of DPPB. The incidence of delayed bleeding, comorbidities, and medications were evaluated from medical records. Characteristics of historical control patients and patients after instruction were compared. Results: A total of 3318 polyps in 1002 patients were evaluated. The control group comprised 1479 polyps in 458 patients and the after-instruction group comprised 1839 polyps in 544 patients. DPPB occurred in 1.1% of polyps in control, and 0.4% in after-instruction. Instruction significantly decreased delayed bleeding, particularly in cases with antithrombotic agents. Hot polypectomy, clip placement, and use of antithrombotic agents were significant independent risk factors for DPPB even after instruction. Conclusion: The rate of delayed bleeding significantly decreased after instruction to check for complete hemostasis. Even after instruction, delayed bleeding can still occur in cases with antithrombotic agents or hot polypectomy.


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