HPV Prevalence and its Association with Perinatal Outcomes among Singleton Mothers: Analysis of Pregnancy Risk Assessment and Monitoring System (PRAMS) Data, 2004-2011

2019 ◽  
Vol 15 (2) ◽  
pp. 143-149 ◽  
Author(s):  
Harpriya Kaur ◽  
Delf Schmidt-Grimminger ◽  
Baojiang Chen ◽  
K.M. Monirul Islam ◽  
Steven W. Remmenga ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Pregnant Women ◽  
Monitoring System ◽  
Large Population ◽  
Perinatal Outcomes ◽  
Hpv Infection ◽  
Adverse Outcomes ◽  
P Value ◽  
Pregnancy Risk

Background: Pregnancy may increase the risk of Human Papillomavirus (HPV) infection because of pregnancy induced immune suppression. The objective of this study was to use a large population-based dataset to estimate the prevalence of HPV infection and its association with adverse outcomes among pregnant women. Methods: We analyzed Pregnancy Risk Monitoring System data from 2004-2011 (N=26,085) to estimate the self-reported HPV infection. Survey logistic procedures were used to examine the relationship between HPV infection and adverse perinatal outcomes. Results: Approximately 1.4% of women were estimated to have HPV infection during their pregnancy. The prevalence of adverse outcomes in this sample was preterm birth (8.4%), preeclampsia (7.5%), low birth weight (6.3%) and premature rupture of membranes (2.8%). Compared to women without HPV infection, HPV infection positive women were much more likely to have had other infections such as chlamydia (9.23% vs. 2.12%, p-value <.0001), Group B Strep (21.7% vs. 10.04%, p-value <.0001), and herpes (7.17% vs. 1.07%, p-value <.0001). After adjusting for other risk factors including other infections, HPV infection was significantly associated with low birth weight (OR: 1.94, 95% CI: 1.14-3.30). Conclusion: The study indicated a potential association between HPV infection and low birth weight. Because pregnant women with HPV infection are at higher risk of other infections, future research may focus on the roles of co-infection in the development of adverse perinatal effects.

scholarly journals Faktor Risiko Bayi Berat Lahir Rendah di Rumah Sakit Umum Daerah Haji Makassar

2020 ◽  
Vol 1 (1) ◽  
pp. 16
Author(s):  
Hatijar Hatijar
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Nutritional Status ◽  
Pregnant Women ◽  
Maternal Age ◽  
Health Workers ◽  
Sampling Technique ◽  
P Value ◽  
Cross Sectional ◽  
Low Birth Weight Babies

Low birth weight babies are babies born with a weight less than 2500 grams. LBW (low birth weight) affects the high mortality rate in infants and is at risk of experiencing obstacles in growth and development. LBW is generally caused due to lack of nutrition and nutritional needs from mother to fetus while pregnant women aged less than 20 years and more than 35 years have the risk of giving birth to LBW. The purpose of this study is to determine the risk factors that cause LBW based on maternal age and nutritional status. The research method used was observational with a cross sectional study approach. The sampling technique was random sampling at the Regional Haji Makassar General Hospital in the January to July 2015 period with a total sample of 65 people. Analysis using the Chi Square Test. The results showed that there was a relationship between maternal age, nutritional status of LBW with a value (p value = 0.00 <α = 0.05). Maternal age and nutritional status are factors that influence low birth weight where the results of the study indicate that there is a relationship between maternal age and nutritional status on the incidence of low birth weight. To reduce the incidence of low birth weight, it is necessary to increase counseling about the causes of low birth weight babies by health workers, especially midwives to pregnant women to prevent the risk of low birth weight birth.

Fetal and Maternal Outcome Asymptomatic vs. Symptomatic Covid Positive Pregnant Women

2021 ◽  
Vol 15 (10) ◽  
pp. 3423-3425
Author(s):  
Amna Najam ◽  
Samreen Fakeer Muhammad ◽  
Samia Saifullah ◽  
Maryam Shoaib ◽  
Maria Anwar
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Cesarean Section ◽  
Pregnant Women ◽  
Apgar Score ◽  
Adverse Outcomes ◽  
Maternal Outcomes ◽  
Group A ◽  
Nicu Admission ◽  
Group B

Objective: The aim of this study is to compare the fetal and maternal outcomes in between asymptomatic and symptomatic COVID positive pregnant women. Study Design: Retrospective cohort study Place and Duration: The study was conducted at Gynae and Obs department of Sandeman Provincial Hospital, Quetta for duration of six months from November 2020 to April 2021. Methods: One hundred and ten pregnant women with ages 18-45 years had corona virus disease were presented. Informed written consent was taken from all patients for detailed demographics. COVID -19 was diagnosed by PCR. 55 patients had symptoms of coronavirus were included in group A and 55 patients did not show symptoms were included in group B. Frequency of pre-eclampsia, gestational diabetes mellitus and post-partum haemorrhage were calculated. Maternal adverse outcomes (cesarean section, instrumental delivery, induction of labor and prolong labor, hypertensive disorder) were calculated among both groups. Fetal outcomes perinatal mortality, Low birth weight, Low Apgar score and NICU admission were observed. SPSS 20.0 version was used to analyze all data. Results: Mean age of the patients in group A was 28.47±3.18 years with mean BMI 24.03±5.24 Kg/m2 and in group B mean age was 27.99±4.17 years with mean BMI 24.44±6.41 Kg/m2. Maternal outcomes (cesarean section, instrumental delivery, induction of labor and prolong labor,) in symptomatic group were significantly higher than that of asymptomatic group. Fetal outcomes, perinatal mortality in group A 9 (16.4%) and in group B was 5 (9.1%), low birth weight in group A was among 21 (38.2%) and in group B was 10 (18.2%), low apgar score in group A was 11 (20%) and in group B was 8 (14.4%), 15 (27.3%) in group A went to NICU admission and 3 (5.5%) patient in group II admitted to NICU. Conclusion: In this study we concluded that adverse outcomes among symptomatic COVID pregnant women were higher than that of asymptomatic coronavirus pregnant women in terms maternal and perinatal outcomes. Keywords: Pregnant women, Coronavirus, Symptomatic, Asymptomatic, Adverse Outcomes

scholarly journals Hubungan Anemia Pada Ibu Hamil Terhadap Kejadian BBLR di RSIA Sitti Khadijah 1 Makassar

2021 ◽  
Vol 2 (1) ◽  
pp. 27-35
Author(s):  
KHartina Burhan ◽  
Dahliah Dahliah ◽  
Nevi Sulvita Karsa
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Pregnant Women ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Mild Anemia ◽  
Mother And Child ◽  
Moderate Anemia ◽  
Child Hospital

In 2011, there were 32.4 million pregnant women aged 15-49 years in the world experiencing anemia. Data (WHO 2011) shows that around (30%) pregnant women in Indonesia experience anemia. This figure is higher compared to some other countries in Southeast Asia such as Malaysia (27%), Singapore (28%), and Vietnam (23%). This study aims to determine the relationship of anemia in pregnant women with the incidence of low birth weight babies (LBW) in the Mother and Child Hospital Sitti Khadijah 1 Makassar in 2018. Research conducted is descriptive analytic using cross sectional method in which a study, variables including risk factors and variables including effects are observed at once at the same time. Based on data from 70 pregnant women who have anemia, there are 66 pregnant women classified as mild anemia (94.3%) and 4 pregnant women with moderate anemia category (5.7%). Of the 23 pregnant women who gave birth to LBW babies were categorized into mild anemia as many as 22 (31.4%) and moderate anemia as much as 1 (1.42%). Based on the chi-square statistical test results obtained p value> 0.05 (p = 0.601) which means there is no significant relationship between anemia in pregnant women with the incidence of low birth weight in the Mother and Child Hospital Sitti Khadijah 1 Makassar in 2018.

Relationship between the nutritional status of pregnant women and the incident of Low Birth Weight infant

2020 ◽  
Vol 1 (3) ◽  
pp. 58-62
Author(s):  
Mardiaturrahmah Mardiaturrahmah ◽  
Anjarwati Anjarwati
Keyword(s):  
Birth Weight ◽  
Mortality Rate ◽  
Infant Mortality ◽  
Low Birth Weight ◽  
Nutritional Status ◽  
Pregnant Women ◽  
Infant Mortality Rate ◽  
P Value ◽  
Case Group ◽  
Control Approach

The maternal mortality rate is 19,500 to 20,000 people every year or occurs every 26-27 minutes. The caus of maternal death is bleeding 30.5%, infection 22,5%, gestosis 17,5 and anesthesia 2%.  The infant mortality rate is around 10,000 to 280,000 per 18-20 minutes. The cause of infant mortality is due to Low Birth Weight (LBW) of 15/1000%.  The infant mortality rate in Indonesia is still the highest problem in other ASEAN countries. The infant mortality rate in Indonesia from 2008 was around 248 per 100,000 live births. Basic Health Research (RISKESDA) 2013 shows there are still 10,2% of babies with LBW, which is less than 2,500 grams. Neonatal death because LBW is basically affected by the nutritional status of pregnant women. This study aims to determine the relationship between the nutritional status of pregnant women and the  incidence  of  LBW. This  quantitative  research  uses  a  case  control  approach  using  a  retrospective approach. The population in this study were mothers who had given birth to babies during the last two years (2016-2017). The sampling technique uses total sampling for control cases by using a ratio of 1: 1 for the case group of 40: 40 samples. Analysis using Chi Square with p value 0,000 (OR=3,500, CI 95%=2,313-5,296). There is a relationship between nutritional status of pregnant women and the incidence of LBW. Health Technology Assessment (HTA) which can seek 1000 first day of life can be a breakthrough in assessing and providing interventions of nutrition in families, especially in pregnant women.

AN EPIDEMIOLOGICAL STUDY ON THE PREVALENCE OF HYPOTHYROIDISM IN PREGNANT WOMEN AND ITS OUTCOME

2021 ◽  
pp. 48-50
Author(s):  
Vinita singh ◽  
Sneha kumari
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Pregnant Women ◽  
Neonatal Outcome ◽  
Reproductive Age ◽  
P Value ◽  
Overt Hypothyroidism ◽  
Thyroid Disorder ◽  
Neonatal Complications ◽  
In Pregnancy

Thyroid disorders are the most common endocrine disorders affecting women of reproductive age group Hypothyroidism is common in pregnancy with an estimated prevalence of 2-3% Maternal hypothyroidism leads to many maternal and perinatal complications like miscarriage, gestational diabetes mellitus, pre-eclampsia, pre-term labor, placental abruption, and fetal death. AIMS AND OBJECTIVE: To nd out the effect of hypothyroidism on the course of pregnancy, to study the neonatal outcome, to know the prevalence of subclinical and overt hypothyroidism in pregnant women. MATERIALS AND METHODS: This prospective study was conducted in the department of Obstetrics and Gynecology, Nalanda medical college and hospital, Patna. All pregnant women attending the obstetric unit during this period were included in the study after informed consent 10 ml of blood sample of pregnant women was drawn at the rst visit in the rst trimester; then it was centrifuged and stored at -70 degree Celsius until assays, which were done after delivery, TFT was assessed by quantitative analysis of serum TSH and FT4 (ELISA). The pregnancy outcome variables like miscarriages, preterm deliveries, IUGR, preeclampsia, anemia, low birth weight, intrauterine fetal demise, antepartum hemorrhage, stillbirth, postpartum hemorrhage, birth asphyxia were studied. The neonatal outcome was also studied. The statistical analysis was done using the odds ratio. P-value <0.05 was considered signicant. RESULTS: Out of the 250 pregnant women 25 had hypothyroidism (9.5%). The prevalence of subclinical hypothyroidism was more as compared to the overtone (Table 2). Abortions were seen in 12.5% of subclinical and 11.1% of overt hypothyroid women. PIH and abruptions were signicantly higher in subclinical cases (P<0.05) while in the overt group both complications were higher as compared to the normal women but the p-value was not signicant for abruption. More of the hypothyroid women had preterm delivery (37.5% in subclinical and 44.4% in the overt group), Regarding neonatal complications, IUD and Early neonatal deaths were signicantly higher in overt hypothyroidism (P<0.01) Hypothyroid women had more low birth weight babies (31.25% in subclinical and 35.5% in overt) and IUGR babies (18.70% in subclinical and 22.21% in overt), CONCLUSION: The present study shows that, though the occurrence of hypothyroidism in pregnancy is less yet it causes many maternal and neonatal complications therefore universal screening of thyroid disorder should be done in pregnancy.

scholarly journals A comparison of obstetrics and perinatal outcomes of teenagers and older women: Experiences from rural South Africa

2010 ◽  
Vol 2 (1) ◽  
Author(s):  
Monjurul Hoque ◽  
Shahnaz Hoque
Keyword(s):  
South Africa ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Pregnant Women ◽  
Older Women ◽  
Teenage Pregnancy ◽  
Perinatal Outcomes ◽  
Public Health Problem ◽  
Binary Logistic Regression ◽  
Chi Square

Background: Teenage pregnancy is a known risk factor for a negative pregnancy outcome and poses a health risk to teenagers; it is thus considered a public health problem. It is also an indicator of problems with the sexual and reproductive health of a country’s young population. In South Africa, most of the adolescent pregnancies are to be found within the context of unstable relationships with the father of the baby and are unplanned or unwanted.Objectives: This study estimates and compares the incidence of adverse obstetric and perinatal outcomes of teenage women with older women, to identify specific health needs of teenage mothers during pregnancy and delivery.Methods:A retrospective cohort study targeted pregnant women who delivered at Empangeni Hospital from April to December 2005, whilst comparing the obstetric and perinatal outcomes of all teenage (ages < 19 years) pregnant women with those of older pregnant women (ages ≥ 19 years) for this study period. Data were collected from the labour ward delivery registry. Pearson’s chi-square test was performed to measure the level of significance (alpha = 0.05) for association amongst variables. The student t-test was used to find the significance difference between two proportions and the binary logistic regression method was employed to find the significant predictor for outcome variables.Results:There were 7836 deliveries over the study period, of which 1236 (16%) were teenage mothers.The rate of gestational age at delivery (e.g. pre-term delivery of 12%), vaginal and forceps deliveries,foetal presentation at birth, multiple pregnancies, low birth-weight and live births deliveries and mean Apgar scores were similar for both groups. The caesarean delivery rate (20%) and macerated stillbirth rate (1.1%) were significantly lower (p < 0.05) for teenagers than for older women.Conclusion: Although there was a higher rate of teenage pregnancy, it did not appear that it was associated with extra perinatal negative outcome such as preterm delivery, low birth-weight delivery and stillbirth. However, strategies are urgently needed to delay conception and improve the socio-economic development of teenage girls.

scholarly journals Study of Vaginal Group-B Streptococcal Colonization in Pregnant Women Attending a Tertiary Care Centre of Agartala

2020 ◽  
Vol 7 (48) ◽  
pp. 2815-2819
Author(s):  
Argha Mallya Debbarman ◽  
Ashis Kumar Rakshit ◽  
Jahar Lal Baidya ◽  
Dhruba Prasad Paul
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Pregnant Women ◽  
Preterm Delivery ◽  
Tertiary Care ◽  
Group B Streptococcus ◽  
P Value ◽  
Vaginal Colonization ◽  
Group B ◽  
Pregnant Mothers

BACKGROUND Lancefield Group-B Streptococcus (GBS) emerged as a significant neonatal pathogen with mortality rates of 15 - 50 % in western countries during 1970s. In India, incidence of invasive neonatal GBS diseases is around 0.17 per 1000 live birth and probably is underestimated. Hence, the study was undertaken to evaluate the vaginal GBS colonization in pregnant women along with the neonatal outcome. METHODS The study was single centered, hospital based observational cross-sectional study done in the dept. of Obstetrics & Gynaecology at Agartala Government Medical College (AGMC), and GBP Hospital for one & half years (Jan’ 16 - June’ 17). 250 Pregnant mothers with 31 to 40 weeks of gestation with singleton pregnancy, delivering either by Caesarean section & Vaginal delivery, were included in this study. They were recruited from obstetrics OPD and casualty of AGMC & GBP Hospital. During 1 st pelvic examination, two low vaginal swabs were taken for Gram Staining, and for determination of ß-hemolytic colony in blood agar. After identification of GBS from genitalia, outcome of neonates in these positive cases were evaluated for up to 28 days after delivery. RESULTS GBS was found in 8.8 % of total women recruited and was more common in multi-gravida. GBS vaginal colonization was significantly associated with low birth weight, and preterm delivery (p value 0.01) which is significant. CONCLUSIONS Prevalence of vaginal GBS colonization is more in pregnant mothers, more in multigravidas & is associated with low-birth-weight neonates and preterm delivery. So, there is a need to formulate guidelines for incorporation of detection of vaginal colonization in multi gravidas to determine its prevalence. KEYWORDS Group-B Streptococcus (GBS), Multigravidas, Colonization, Neonates, Pregnant Women

scholarly journals Perinatal Outcomes of Hypertensive Pregnancy: A Case Control Study

2019 ◽  
Vol 17 (2) ◽  
pp. 39-42
Author(s):  
Niraj Acharya ◽  
Diwas Dhungana ◽  
Veena Gupta
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Perinatal Outcomes ◽  
College Teaching ◽  
Fetal Outcome ◽  
Control Group ◽  
P Value ◽  
Case Group ◽  
Low Birth Weight Infants ◽  
Medical College

Background: Hypertensive disorders of pregnancy (HDP) are one of the maternal diseases that cause the most detrimental effects to the mother and the fetus. Objective: This study was conducted to compare the perinatal outcomes of neonates delivered by hypertensive mothers and normal mothers. Methods: This comparative hospital based study was conducted in Nepalgunj Medical College Teaching Hospital, Kohalpur from December 2014 to December 2015. Fifty mothers fulfilling the inclusion criteria and their fetal outcome in form of still birth and newborn babies were taken for the study and 50 healthy mothers with normotensive pregnancies and their newborn babies or fetal outcome were taken as control. They were followed up till their hospital stay in NICU or postnatal ward and final outcomes were noted. Results: The prevalence of HDP in our hospital was 2.16%. Among neonates, 27(54%) in case group and 9(18%) in control group were low birth weight which is statistically significant. It was found that 18(36%) neonates in case group and 7(14%) neonates in control group were IUGR(Intrauterine growth retardation). Seventeen (34%) neonates in case group were preterm as compared to 2(4%) neonates in control group (p value < 0.001). Conclusion: Pregnancies complicated by hypertension were characterized by an increase in the rate of preterm delivery and low birth weight infants compared with normal pregnancies.

scholarly journals Bacterial Vaginosis and Pregnancy Outcome in Lagos, Nigeria

2016 ◽  
Vol 3 (1) ◽  
Author(s):  
Bosede B. Afolabi ◽  
Olusanjo E. Moses ◽  
Oyinlola O. Oduyebo
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Bacterial Vaginosis ◽  
Pregnant Women ◽  
Pregnancy Outcome ◽  
Prevalence Rate ◽  
Adverse Outcomes ◽  
University Teaching ◽  
Premature Rupture Of Membranes ◽  
Premature Rupture

Abstract Background.  Bacterial vaginosis (BV) is a complex clinical syndrome characterized by alterations in the normal vaginal flora and a malodorous discharge when symptomatic. In pregnancy, BV has been associated with adverse outcomes such as miscarriage, premature rupture of membranes, preterm birth, and low birth weight. This study was conducted to determine the prevalence and associations of BV and pregnancy outcomes among pregnant women in Lagos University Teaching Hospital (LUTH). Methods.  We conducted a prospective observational study with high vaginal swabs obtained from consecutive newly registered antenatal women between 14 and 36 weeks gestation. The women were monitored until delivery, and their pregnancy outcome and demographic data were obtained using an interviewer-administered questionnaire. Results.  Bacterial vaginosis was diagnosed by Nugent score in 64 of 246 women, giving a prevalence rate of 26%. Bacterial vaginosis was significantly associated with preterm delivery (risk ratio [RR], 2.68; 95% confidence interval [CI], 1.44–4.98), low birth weight (RR, 3.20; 95% CI, 1.29–7.94), and premature rupture of membranes (RR, 6.75; 95% CI, 3.11–14.67). The association between BV and miscarriage (&lt;28 weeks gestation) and neonatal admission for various morbidities was not statistically significant. Conclusions.  The prevalence rate of BV among pregnant women in LUTH is high and is significantly associated with adverse pregnancy outcome. Routine screening and treatment of women preconceptually may enable interventions to prevent these adverse outcomes.

scholarly journals Determinant Analysis of Low Birth Weight among Young Pregnant Women in Blitar District

2020 ◽  
Vol 4 (1) ◽  
pp. 86-91
Author(s):  
Etti Suryani ◽  
Yuly Peristiowati ◽  
Yenny Puspitasari
Keyword(s):  
Logistic Regression ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Antenatal Care ◽  
Pregnant Women ◽  
Binary Logistic Regression ◽  
P Value ◽  
Routine Antenatal Care ◽  
Determinant Analysis ◽  
Cluster Random Sampling

Background : Low birth weight, commonly called LBW, is a major cause of infant mortality in Indonesia whereas its prevalence tends to increase from year to year. Purpose: This study aimed to analyze the determinants of gravida status, routine antenatal care, and comorbidities in LBW among young pregnant women in Blitar. Method : The research design was case-control using proportional cluster random sampling with a sample of 223 respondents. The data were analyzed with the binary logistic regression. Results : The results showed 214 respondents (96%) were primigravida, 23 respondents (10.3%) were not attended antenatal care routinely, 66 respondents (30%) had comorbidity, and 20 respondents (9%) delivered LBW baby. The statistical analysis of logistic regression showed there was no influence from gravida status and comorbidities, and routine antenatal care indicateda p-value of 0.000 which meant it was determined LBW among <20 years old pregnant women in Blitar. The interpretation of odd value was the group of < 20 years old pregnant women who were not attended routine ANC had a risk of 10 times to deliver LBW baby compared to the group of < 20 years old pregnant women who attended routine ANC. Conclusion : This study concluded that routine antennal care might prevent LBW for young pregnant women

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