THE STUDY OF MATERNAL AND FETAL OUTCOME IN PREGNANT WOMEN WITH THYROID DISORDER: A PROSPECTIVE STUDY IN INDORE REGION

2021 ◽  
pp. 69-71
Author(s):  
Preeti Gupta ◽  
Manila Jain ◽  
Nand K Gupta ◽  
Umesh K Gupta
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Adverse Effects ◽  
Pregnant Women ◽  
Thyroid Dysfunction ◽  
Thyroid Stimulating Hormone ◽  
Thyroid Disorder ◽  
Cross Sectional ◽  
Foetal Outcome ◽  
Nicu Admission

BACKGROUND: Thyroid disorder is very common disorders in pregnancy. It is well established that overt and subclinical thyroid dysfunction has adverse effects on mother and the foetus like miscarriages, preterm delivery, preeclampsia, eclampsia, polyhydramnios, placental abruption, postpartum haemorrhage, low birth weight, fetal distress, NICU admission. With this background, we are conducting a study to know the effect of thyroid disorder on pregnancy and its maternal and foetal outcome. METHODS: The present study was carried out in Index Medical College, Indore, MP, India in Department of physiology in collaboration with Department of Obstetrics & Gynecology. It is a prospective random cross-sectional study done over 180 pregnant women (90 pregnant women with thyroid disorder and 90 with normal thyroid) which includes known cases of thyroid disorder. Serum thyroid stimulating hormone (TSH), fT3, and fT4 tests were apart from the routine blood sample investigations as per FOGSI-ICOG good clinical practice recommendation. Patients are followed up till delivery, and their obstetrics and perinatal outcomes are noted. RESULTS: In our study prevalence of thyroid dysfunction was 10.4%. Out of these 90 patients with thyroid dysfunction, complications associated were pre-eclampsia (14.4%), abortions (13.3%), maternal anaemia (11.1%), preterm labour (7.8%), still birth (5.6%), abruption placenta (4.4%). Out of 90 patients with thyroid dysfunction, foetal complications seen were low birth weight (22.2%), NICU admission (15.6%), hyperbilirubinemia (14.4%) and foetal distress (5.6%). CONCLUSIONS: Our result demonstrated that the thyroid disorders during pregnancy have adverse effects on maternal and foetal outcome emphasizing the importance of routine antenatal thyroid screening.

scholarly journals The study of maternal and foetal outcome in pregnant women with thyroid disorder

2019 ◽  
Vol 8 (5) ◽  
pp. 1802
Author(s):  
Priya Maurya ◽  
Neeta Chaudhary ◽  
Natasha Tyagi ◽  
M. R. Kural ◽  
Kriti Bhatnagar
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Adverse Effects ◽  
Pregnant Women ◽  
Thyroid Dysfunction ◽  
Thyroid Peroxidase ◽  
Thyroid Disorder ◽  
Neonatal Hypothyroidism ◽  
Foetal Outcome ◽  
In Pregnancy

Background: Thyroid disorder is one of the most common disorder in pregnancy. Thyroid disorder is known to be associated with abnormal maternal and foetal outcomes and overlooked in pregnant women because of non-specific symptoms and hypermetabolic state of pregnancy of pregnancy. It is well established that not only overt, but subclinical thyroid dysfunction also has adverse effects on mother and the foetus like miscarriages, preterm delivery, pre-eclampsia, eclampsia, polyhydramnios, placental abruption, postpartum haemorrhage, low birth weight, neonatal hypothyroidism. Decreased availability of thyroid hormones may also impair neurological and intellectual development of foetus. With this background, we are conducting a study to know the effect of thyroid disorder on pregnancy and its maternal and foetal outcome.Methods: The present study was conducted in Muzaffarnagar Medical College, Uttar Pradesh, India in collaboration of department of Gynecology and Obstetrics and Pediatrics Department. It is a prospective random cross-sectional study done over 400 pregnant women which includes known cases of thyroid disorder. Serum thyroid stimulating hormone (TSH) test was apart from the routine blood sample investigations as per FOGSI-ICOG good clinical practice recommendation. fT3, fT4 and thyroid peroxidase antibody test were done in patients with a deranged TSH value. Patients were followed up till delivery, and their obstetrics and perinatal outcomes were noted and managed.Results: In present study out of 400 cases, 25 cases are hypothyroidism and 16 cases are hyperthyroidism in pregnancy. Out of these 41 patients with thyroid dysfunction, complications associated were abortions (14.63%), maternal anaemia (9.7%), pre-eclampsia (12.2%), preterm labour (9.76%), abruption placenta (4.88%), IUGR (2.4%), Still birth (7.32%). Out of 41 patients with thyroid dysfunction, foetal complications seen were hyperbilirubinemia (12.2%), Foetal distress (4.88%), NICU admission (17.07%) and low birth weight (21.95%).Conclusions: Thyroid disorder in pregnancy have adverse effects on maternal and foetal outcome emphasizing the importance of routine antenatal thyroid screening.

scholarly journals Overt and subclinical hypothyroidism among Bangladeshi pregnant women and its effect on fetomaternal outcome

2015 ◽  
Vol 40 (2) ◽  
pp. 52-57 ◽  
Author(s):  
M Sharmeen ◽  
PA Shamsunnahar ◽  
TR Laita ◽  
SB Chowdhury
Keyword(s):  
Adverse Effects ◽  
Pregnant Women ◽  
Subclinical Hypothyroidism ◽  
Thyroid Dysfunction ◽  
Perinatal Outcomes ◽  
Fetal Outcome ◽  
Thyroid Stimulating Hormone ◽  
Overt Hypothyroidism ◽  
Adequate Treatment ◽  
In Pregnancy

Objectives: Thyroid disorders are among the common endocrine problems in pregnant women. It is now well established that not only overt but subclinical thyroid dysfunction also has adverse effects on maternal and fetal outcome. There are few data from Bangladesh about the prevalence of thyroid dysfunction in pregnancy. With this background, this study aims to find out thyroid dysfunction (both overt and subclinical hypothyroidism) in pregnancy and its impact on obstetrical outcome.Methods: We studied the evaluation of 50 admitted pregnancies corresponding to 29 women with subclinical hypothyroidism and rest 21 was overt hypothyroidism. Detailed history and examination were performed. Apart from routine obstetrical investigations, Thyroid Stimulating Hormone (TSH) estimation was done. Their obstetrical and perinatal outcomes were noted.Results: Overt hypothyroidism was significantly (p<0.05) higher in 25 to 44 years age group. However two and three abortions were significantly (p<0.05) higher in overt hypothyroidism patients. In sub clinical hypothyroidism 86.2% conceived firstly within 2 years and 66.7% in overt hypothyroidism patients conceived firstly in between 3 to 5 years after marriage. Overt hypothyroids were prone to have pregnancy-induced hypertension 42.9%, intrauterine growth restriction (P=0.001) and gestational diabetes (38.1%) as compared to subclinical cases. Neonatal complications were significantly more in overt hypothyroidism group. Mean TSH level was significantly (p<0.05) higher in overt hypothyroidism patients but mean FT4 level was almost similar in both groups. Majority of the patient underwent caesarean section in both groups due to associated medical and obstetrical complications. None of the babies showed hypothyroidism by cord blood tests. In this analysis our results showed that overt hypothyroidism among Bangladeshi pregnant women are associated with more maternal complication & adverse parental outcome than subclinical hypothyroidism. The adequate treatment of hypothyroidism during gestation minimizes risks and generally, makes it possible for pregnancies to be carried to term without complications. Significant adverse effects on maternal and fetal outcome were seen emphasizing the importance of routine antenatal thyroid screening.Bangladesh Med Res Counc Bull 2014; 40 (2): 52-57

scholarly journals Faktor Risiko Bayi Berat Lahir Rendah di Rumah Sakit Umum Daerah Haji Makassar

2020 ◽  
Vol 1 (1) ◽  
pp. 16
Author(s):  
Hatijar Hatijar
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Nutritional Status ◽  
Pregnant Women ◽  
Maternal Age ◽  
Health Workers ◽  
Sampling Technique ◽  
P Value ◽  
Cross Sectional ◽  
Low Birth Weight Babies

Low birth weight babies are babies born with a weight less than 2500 grams. LBW (low birth weight) affects the high mortality rate in infants and is at risk of experiencing obstacles in growth and development. LBW is generally caused due to lack of nutrition and nutritional needs from mother to fetus while pregnant women aged less than 20 years and more than 35 years have the risk of giving birth to LBW. The purpose of this study is to determine the risk factors that cause LBW based on maternal age and nutritional status. The research method used was observational with a cross sectional study approach. The sampling technique was random sampling at the Regional Haji Makassar General Hospital in the January to July 2015 period with a total sample of 65 people. Analysis using the Chi Square Test. The results showed that there was a relationship between maternal age, nutritional status of LBW with a value (p value = 0.00 <α = 0.05). Maternal age and nutritional status are factors that influence low birth weight where the results of the study indicate that there is a relationship between maternal age and nutritional status on the incidence of low birth weight. To reduce the incidence of low birth weight, it is necessary to increase counseling about the causes of low birth weight babies by health workers, especially midwives to pregnant women to prevent the risk of low birth weight birth.

Fetal and Maternal Outcome Asymptomatic vs. Symptomatic Covid Positive Pregnant Women

2021 ◽  
Vol 15 (10) ◽  
pp. 3423-3425
Author(s):  
Amna Najam ◽  
Samreen Fakeer Muhammad ◽  
Samia Saifullah ◽  
Maryam Shoaib ◽  
Maria Anwar
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Cesarean Section ◽  
Pregnant Women ◽  
Apgar Score ◽  
Adverse Outcomes ◽  
Maternal Outcomes ◽  
Group A ◽  
Nicu Admission ◽  
Group B

Objective: The aim of this study is to compare the fetal and maternal outcomes in between asymptomatic and symptomatic COVID positive pregnant women. Study Design: Retrospective cohort study Place and Duration: The study was conducted at Gynae and Obs department of Sandeman Provincial Hospital, Quetta for duration of six months from November 2020 to April 2021. Methods: One hundred and ten pregnant women with ages 18-45 years had corona virus disease were presented. Informed written consent was taken from all patients for detailed demographics. COVID -19 was diagnosed by PCR. 55 patients had symptoms of coronavirus were included in group A and 55 patients did not show symptoms were included in group B. Frequency of pre-eclampsia, gestational diabetes mellitus and post-partum haemorrhage were calculated. Maternal adverse outcomes (cesarean section, instrumental delivery, induction of labor and prolong labor, hypertensive disorder) were calculated among both groups. Fetal outcomes perinatal mortality, Low birth weight, Low Apgar score and NICU admission were observed. SPSS 20.0 version was used to analyze all data. Results: Mean age of the patients in group A was 28.47±3.18 years with mean BMI 24.03±5.24 Kg/m2 and in group B mean age was 27.99±4.17 years with mean BMI 24.44±6.41 Kg/m2. Maternal outcomes (cesarean section, instrumental delivery, induction of labor and prolong labor,) in symptomatic group were significantly higher than that of asymptomatic group. Fetal outcomes, perinatal mortality in group A 9 (16.4%) and in group B was 5 (9.1%), low birth weight in group A was among 21 (38.2%) and in group B was 10 (18.2%), low apgar score in group A was 11 (20%) and in group B was 8 (14.4%), 15 (27.3%) in group A went to NICU admission and 3 (5.5%) patient in group II admitted to NICU. Conclusion: In this study we concluded that adverse outcomes among symptomatic COVID pregnant women were higher than that of asymptomatic coronavirus pregnant women in terms maternal and perinatal outcomes. Keywords: Pregnant women, Coronavirus, Symptomatic, Asymptomatic, Adverse Outcomes

scholarly journals Kecacingan, malaria, dan status besi ibu hamil di Kabupaten Batang Hari Provinsi Jambi

2009 ◽  
Vol 5 (3) ◽  
pp. 120
Author(s):  
Helfiyan Helfiyan ◽  
Hamam Hadi ◽  
Siti Helmyati
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Pregnant Women ◽  
Ascaris Lumbricoides ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Necator Americanus ◽  
Before And After

Background: Anemia among pregnant women may increase abortion, premature, low birth weight and even mortality before and after delivery. Factors causing anemia in Indonesia are lack of Fe, inadequate intake, demanding needs, and lack of nutrient facilitating Fe absorption. Besides, infection such as worm and malaria may cause anemia as well. Result of household health survey 2001 stated that prevalence of pregnant women with anemia was 40% in Indonesia. In Jambi Province, it was 39% in 2003 and 42.3% for Batang Hari Regency while infection of malaria was 50.0% in all age groups and many other districts that its environment were woods, humid, and wasted that may increase infection of hookworm.Objective: The study was proposed to know the correlation of hookworm, malaria with anemia among pregnant women by analyzing correlation of hookworm, malaria, and anemia and correlation of hookworm, malaria and Fe status among pregnant women.Method: This was cross sectional study. It held from September until December 2005 in Batang Hari Regency, Jambi Province. Subjects were 132 pregnant women. Examination of blood for Hb, malaria and ferritin were taken together while feces were later.Results: There were no significant correlation of Ascaris lumbricoides infection with anemia (p = 0.36; OR = 2.43), Trichiuris thrichiura infection with anemia (p = 0.30), 2 kinds of worm Ascaris lumbricoides + Trichiuris trichiura with anemia (p = 0.08; OR = 4.87), and infection of Ascaris lumbricoides + Necator americanus with anemia (p = 0.30). There was significant correlation of 3 kinds of worm Ascaris lumbricoides + Trichiuris trichiura + Necator americanus with anemia (p = 0.018; OR = 7.3). There were no significant correlation of Ascaris lumbricoides with ferritin (p = 0.17; OR = 3.23) and Trichiuris trichiura with ferritin (p = 0.25). There was significant correlation of 2 kinds of worm Ascaris lumbricoides + Trichiuris trichiura with ferritin (p = 0.04; OR = 6.4). There was no significant correlation of Ascaris lumbricoides + Necator americanus with ferritin p = 0.25. There were significant correlation of 3 kinds of worm (Ascaris lumbricoides + Trichiuris trichiura + Necator americanus) with ferritin p = 0.007; OR = 9.69 and ferritin with anemia p = 0.0001; OR = 17.45.Conclusion: There was no significant correlation of hookworms Ascaris lumbricoides, Trichiuris trichiura, Ascaris lumbricoides + Trichius trichiura, Ascaris lumbricoides + Necator americanus with anemia. There were significant correlation of infection of Ascaris lumbricoides + Trichiuris trichiura + Necator americanus with anemia and malaria with anemia. There was no correlation of hookworms Ascaris lumbricoides, Trichiuris trichiura, Ascaris lumbricoides + Neca- tor americanus with anemia. There were correlation of infection Ascaris lumbricoides + Trichiuris trichiura and Ascaris lumbricoides + Trichiuris trichiuris + Necator americanus with ferritin, malaria with ferritin, and ferritin with anemia.

scholarly journals Association Between Anaemia And Low Birth Weight Among HIV -Infected Pregnant Women Aged 15 – 49 Years In Zimbabwe : A Cross-Sectional Study

2020 ◽  
Author(s):  
Dorothy T Chisare ◽  
Simbarashe Takuva ◽  
Tariro J. Basera ◽  
Natasha Khamisa ◽  
Jacqueline Witthuhn
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Pregnant Women ◽  
Secondary Data ◽  
Hiv Positive ◽  
Cross Sectional ◽  
Maternal Anaemia ◽  
Hiv Positive Women ◽  
Increased Risk ◽  
The Relationship

Abstract Background In Zimbabwe, almost 25% of infants are born with low birth weight (LBW). LBW accounts for over half of the neonatal deaths in the country. Anaemia during pregnancy has been inconsistently associated with an increased risk of LBW. However, very little data is available from countries where HIV prevalence is high, wherein HIV is also known to be a common risk factor to LBW. This study examined the relationship between maternal anaemia and LBW among HIV-infected pregnant women in Zimbabwe. Methods This was a secondary data analysis of the 2015 Zimbabwe Demography and Health Survey. Data for 809 HIV positive women aged 15-49 years and their infants from all live births preceding the survey by 5 years were included in the study. Modified-Poisson regression methods were used to determine the association between anaemia and LBW while adjusting for other risk factors. Results The prevalence of maternal anaemia and LBW among the HIV-infected pregnant women was 42.3% (n=342) and 16.3% (n =132) respectively. The prevalence of LBW was14.6% (n=50) and 17.6% (n=82) among anaemic and non-anaemic HIV positive women respectively (p=0.264). HIV infected pregnant women with anaemia had a 25% less chance of giving birth to infants with LBW compared to HIV infected mothers without anaemia, however, the association was not statistically significant (RR 0.75; 95% CI 0.53- 1.05). Conclusions The findings demonstrate a high prevalence of anaemia and LBW among HIV infected pregnant women. Nonetheless, maternal anaemia was not associated with LBW. There is a need for adapted monitoring of HIV-positive pregnant women and affordable improved nutrition during antenatal care to reduce the risk of LBW infants and maternal anaemia levels. Further research examining the relationship between maternal anaemia and LBW among HIV positive pregnant women whilst factoring in the role of ART and the severity of anaemia is required.

scholarly journals Hubungan Anemia Pada Ibu Hamil Terhadap Kejadian BBLR di RSIA Sitti Khadijah 1 Makassar

2021 ◽  
Vol 2 (1) ◽  
pp. 27-35
Author(s):  
KHartina Burhan ◽  
Dahliah Dahliah ◽  
Nevi Sulvita Karsa
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Pregnant Women ◽  
P Value ◽  
Chi Square ◽  
Cross Sectional ◽  
Mild Anemia ◽  
Mother And Child ◽  
Moderate Anemia ◽  
Child Hospital

In 2011, there were 32.4 million pregnant women aged 15-49 years in the world experiencing anemia. Data (WHO 2011) shows that around (30%) pregnant women in Indonesia experience anemia. This figure is higher compared to some other countries in Southeast Asia such as Malaysia (27%), Singapore (28%), and Vietnam (23%). This study aims to determine the relationship of anemia in pregnant women with the incidence of low birth weight babies (LBW) in the Mother and Child Hospital Sitti Khadijah 1 Makassar in 2018. Research conducted is descriptive analytic using cross sectional method in which a study, variables including risk factors and variables including effects are observed at once at the same time. Based on data from 70 pregnant women who have anemia, there are 66 pregnant women classified as mild anemia (94.3%) and 4 pregnant women with moderate anemia category (5.7%). Of the 23 pregnant women who gave birth to LBW babies were categorized into mild anemia as many as 22 (31.4%) and moderate anemia as much as 1 (1.42%). Based on the chi-square statistical test results obtained p value> 0.05 (p = 0.601) which means there is no significant relationship between anemia in pregnant women with the incidence of low birth weight in the Mother and Child Hospital Sitti Khadijah 1 Makassar in 2018.

scholarly journals Anemia and Low Birth Weight Risk After Fe Therapy in Pregnancy, Puskesmas Kecamatan Kebayoran Baru

2021 ◽  
Vol 9 (1) ◽  
pp. 109-115
Author(s):  
Dyah Ponco Sudarmaningsih ◽  
◽  
Febrial Hikmah ◽  
N Sri Widada ◽  
Rustiana Tasya Ariningpraja
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Pregnant Women ◽  
Physiological Changes ◽  
Cross Sectional ◽  
Before And After ◽  
In Pregnancy

Physiological changes in pregnant women have an impact on reducing the hemoglobin (Hb) level so that they can experience anemia. Anemia in pregnant women is still a high case and be one of the factors of low birth weight (LBW). Iron (Fe) is consumed routinely is thought to help reduce the risk of anemia, but it's still not known yet between the relation of Fe consumed to LBW incidents. Data were taken by cross sectional as many as 150 samples of pregnant women. The results obtained that 56% of pregnant women had anemia. After Fe therapy doses 60-120 mg/day, Hb levels increased by 0.3 g/dL. Although there were significant differences before and after Fe therapy in pregnant women with anemia, about 74% of pregnant women still had experience anemia despite Fe therapy. Provision of Fe therapy for pregnant women either with a dose of 60-120 mg/day, had not been effective enough in increasing Hb levels. LBW cases were also found in this study, which is around 9.3%. Pregnant women with anemia have a higher risk of LBW. This indicates that offering Fe to pregnant women has not been effective.

AN EPIDEMIOLOGICAL STUDY ON THE PREVALENCE OF HYPOTHYROIDISM IN PREGNANT WOMEN AND ITS OUTCOME

2021 ◽  
pp. 48-50
Author(s):  
Vinita singh ◽  
Sneha kumari
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Pregnant Women ◽  
Neonatal Outcome ◽  
Reproductive Age ◽  
P Value ◽  
Overt Hypothyroidism ◽  
Thyroid Disorder ◽  
Neonatal Complications ◽  
In Pregnancy

Thyroid disorders are the most common endocrine disorders affecting women of reproductive age group Hypothyroidism is common in pregnancy with an estimated prevalence of 2-3% Maternal hypothyroidism leads to many maternal and perinatal complications like miscarriage, gestational diabetes mellitus, pre-eclampsia, pre-term labor, placental abruption, and fetal death. AIMS AND OBJECTIVE: To nd out the effect of hypothyroidism on the course of pregnancy, to study the neonatal outcome, to know the prevalence of subclinical and overt hypothyroidism in pregnant women. MATERIALS AND METHODS: This prospective study was conducted in the department of Obstetrics and Gynecology, Nalanda medical college and hospital, Patna. All pregnant women attending the obstetric unit during this period were included in the study after informed consent 10 ml of blood sample of pregnant women was drawn at the rst visit in the rst trimester; then it was centrifuged and stored at -70 degree Celsius until assays, which were done after delivery, TFT was assessed by quantitative analysis of serum TSH and FT4 (ELISA). The pregnancy outcome variables like miscarriages, preterm deliveries, IUGR, preeclampsia, anemia, low birth weight, intrauterine fetal demise, antepartum hemorrhage, stillbirth, postpartum hemorrhage, birth asphyxia were studied. The neonatal outcome was also studied. The statistical analysis was done using the odds ratio. P-value <0.05 was considered signicant. RESULTS: Out of the 250 pregnant women 25 had hypothyroidism (9.5%). The prevalence of subclinical hypothyroidism was more as compared to the overtone (Table 2). Abortions were seen in 12.5% of subclinical and 11.1% of overt hypothyroid women. PIH and abruptions were signicantly higher in subclinical cases (P<0.05) while in the overt group both complications were higher as compared to the normal women but the p-value was not signicant for abruption. More of the hypothyroid women had preterm delivery (37.5% in subclinical and 44.4% in the overt group), Regarding neonatal complications, IUD and Early neonatal deaths were signicantly higher in overt hypothyroidism (P<0.01) Hypothyroid women had more low birth weight babies (31.25% in subclinical and 35.5% in overt) and IUGR babies (18.70% in subclinical and 22.21% in overt), CONCLUSION: The present study shows that, though the occurrence of hypothyroidism in pregnancy is less yet it causes many maternal and neonatal complications therefore universal screening of thyroid disorder should be done in pregnancy.

scholarly journals Heated tobacco product use and hypertensive disorders of pregnancy and low birth weight: analysis of a cross-sectional, web-based survey in Japan

BMJ Open ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. e052976
Author(s):  
Masayoshi Zaitsu ◽  
Yoshihiko Hosokawa ◽  
Sumiyo Okawa ◽  
Ai Hori ◽  
Gen Kobashi ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Pregnant Women ◽  
Tobacco Product ◽  
Secondary Outcome ◽  
Hypertensive Disorders Of Pregnancy ◽  
Cross Sectional ◽  
Web Based ◽  
Hypertensive Disorders ◽  
The Impact

ObjectivesKnowledge on the impact of heated tobacco product (HTP) use in pregnant women with associated maternal and neonatal risks for hypertensive disorders of pregnancy (HDP) and low birth weight (LBW) is limited. We aimed to assess the status of HTP use among pregnant women in Japan and explore the association of HTP use with HDP and LBW.DesignCross-sectional study.SettingData from the Japan ‘COVID-19 and Society’ Internet Survey study, a web-based nationwide survey.ParticipantsWe investigated 558 postdelivery and 365 currently pregnant women in October 2020.Primary and secondary outcome measuresInformation on HDP and LBW was collected from the postdelivery women’s Maternal and Child Health Handbooks (maternal and newborn records). We estimated the age-adjusted ORs and 95% CIs of ever HTP smokers for HDP and LBW and compared them with those of never HTP smokers in a logistic regression analysis.ResultsThe prevalence of ever and current HTP use were 11.7% and 2.7% in postdelivery women and 12.6% and 1.1% in currently pregnant women, respectively. Among currently pregnant women who were former combustible cigarette smokers, 4.4% (4/91) were current HTP smokers. Among postdelivery women, ever HTP smokers had a higher HDP incidence (13.8% vs 6.5%, p=0.03; age-adjusted OR=2.48, 95% CI 1.11 to 5.53) and higher LBW incidence (18.5% vs 8.9%, p=0.02; age-adjusted OR=2.36, 95% CI 1.16 to 4.87).ConclusionsIn Japan, the incidence of ever HTP use exceeded 10% among pregnant women, and HTP smoking may be associated with maternal and neonatal risks.

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