Clinical Presentation, Biopsy and Surgery of Breast Cancer in Women at Tertiary Care Hospital in Gujrat

2021 ◽  
Vol 15 (8) ◽  
pp. 1806-1808
Author(s):  
Abid Nazir Choudhry ◽  
Asma Tariq ◽  
Tehmina Naz ◽  
Shahid Mahmood ◽  
Kanwal Shahzad

Aim: To detect the clinical presentation, biopsy and surgery of breast cancer in women at tertiary care hospital in Gujrat, Pakistan. Study design: Cross sectional descriptive study. Place and duration of study: This study was conducted in 06 years April 2014 to March 2020 at Aziz Bhatti Shaheed Teaching Hospital Gujrat, Pakistan. Methods: Total 138 women were selected for study that was having breast lump, breast ulcer or abnormal breast (nipple) discharge. Women were admitted for investigations and further plan for treatment. Breast cancer was diagnosed on history, examination and investigations. Complete blood count, serum studies, ultra-sonography of breast, mammography and breast biopsy was planned. Results: Total 138 women were enrolled in the study. Women 25-85 years of age were included in the study. Youngest woman was 27 years of age and the oldest was 85 years of age. Thirty two (23.18%) women were less than 50 years of age and 106(76.81%) women were more than 50 years of age. Conclusions: Breast cancer is the commonest cancer of women and most frequent cause of cancer related deaths. Early diagnosis and appropriate treatment offers the best chance for cure. Histological diagnosis and staging is mandatory prior to treatment. The best treatment of breast cancer is carried out by multidisciplinary team. Keywords: Breast lump, mammography, nipple discharge

Author(s):  
Anjan Adhikari ◽  
Dipesh Chakraborty ◽  
Rania Indu ◽  
Sangita Bhattacharya ◽  
Moumita Ray ◽  
...  

 Objective: Cancer is a disease of uncontrolled division of cells in any part of the body. Breast cancer most common in women accounts for 13% of the death worldwide. The objective of the present study was to evaluate the drug prescription pattern of breast carcinoma patients in a tertiary care hospital of West Bengal.Methods: This was a cross-sectional observational questionnaire-based study done for a period of 6 months at the Department of Pharmacology in Collaboration with the Department of Surgery and Department of Radiotherapy of a Tertiary Care Hospital at Kolkata, West Bengal, India. Female patients with breast cancer (originated from epithelial tissues) of different types and grade attending surgery outdoor patient department were taken as subjects for the study, after signing informed consent.Results: The present study evaluated 28 patients (n=28) diagnosed as breast cancer by the physicians of the department of surgery and radiotherapy. It was observed that breast cancer was mostly found in the middle age group. Breast carcinoma in postmenopausal women accounted to 75%. The most prevalent breast cancer was invasive ductal carcinoma, accounting to 75% of the study population. 5-Fluorouracil, epirubicin, doxorubicin, cyclophosphamide, docetaxel/paclitaxel, and carboplatin were mostly used as chemotherapeutic agent.Conclusion: Breast carcinoma being a prevalent type of cancer in females, the present study tried to evaluate the pattern of prescribing chemotherapeutic agents for breast cancer patients in a tertiary care hospital. Such study is essential to evaluate and refine the therapeutic regimen of the cancer patients to reduce their sufferings.


2021 ◽  
Vol 12 (9) ◽  
pp. 75-78
Author(s):  
Deepak Kumar Sahoo ◽  
Mintu Mohan Nandi ◽  
Srijan Basu ◽  
Sanjay Chatterjee ◽  
Amit Kumar Das

Background: Breast cancer is one of the most common cancer in women. BC represents a heterogeneous group of tumors that are diverse in behavior, outcome, and response to therapy. Aims and Objective: The present study was undertaken to assess various clinical parameters and to evaluate correlation with histo-pathological grading in breast carcinoma patients. Materials and Methods: The study was conducted in the Surgical outpatient department and Indoor surgical wards of Deben Mahato Sadar Hospital (DMSH), Purulia, West Bengal from July, 2019 to December, 2020. 104 patients with diagnosis of BC aged between 20 years to 80 years were selected. Results: Among 104 patients, 41.3% patients were in the group of 41-50years. This study revealed that the patient had mostly IDC i.e. 78.8% and had triple negative BC (51.9%). Association of HPE vs. Stage, subtypes vs stage and Tru-cut biopsy vs HPE were statistically significant. Conclusion: The study showed that breast cancer tends to present in middle aged women and positively correlate with the present markers of bad prognosis.


2021 ◽  
Vol 15 (8) ◽  
pp. 1800-1805
Author(s):  
Muntiha Sarosh ◽  
Faiza Ghafoor ◽  
Najma Parveen ◽  
Rabiya Shahid ◽  
Shifa Khalil Ur Rehman

Aim: To determine Incidence of Polycystic Ovarian Syndrome and its clinical presentation in a tertiary care Hospital. Study Design: A Cross sectional study. Place and duration of study: The study was conducted in the Department of Obs. & Gynae, Avicenna Medical College and Hospital, Lahore for a period of six months, January 2020 to June 2020. Methodology: A total of 753 patients attending the gynecological outpatient department were included in the study. Among these the women presenting with clinical picture of menstrual irregularities weight gain, hirsutism and subfertility were evaluated for diagnosis of PCOS. Radiological findings by pelvic U/S were confirmed. Results: 169 women out of 753 patients were found to have PCOS. The incidence was thus 22.44%. Maximum number of women were overweight, BMI (25-29.9Kg/m2). 113(66.86%) presented with oligomennorrea followed by hirsutism and amenorrhea. 57.1% of married women with PCOD had subfertility. Conclusion: Polycystic ovarian Syndrome is common in our population. It is more frequently seen in unmarried obese women. Menstrual irregularity is the most common clinical presentation. Ultrasound criteria is a valuable tool to diagnose the Polycystic Ovarian Disease. Keywords: Polycystic 0varian Syndrome, oligomenorrhoea, amenorrhoea, hirsutism, obesity


2021 ◽  
Vol 15 (10) ◽  
pp. 2739-2741
Author(s):  
Asiya Shabbir ◽  
Shahid Hussain ◽  
Muhammad Asif

Objectives: To assess the recurrence rate of breast cancer after modified radical mastectomy in cases of breast cancer at tertiary care hospital. Material and methods: Between the March 2020 to September 2020 (over the period of 6 months) total 110 women with breast cancer having age range 30-60 years were recruited from Department of Surgery, Bahawal Victoria Hospital Bahawalpur for this cross sectional study. Modified radical mastectomy was performed in all selected patients. At 6 months follow up, all the selected patients was again examined for recurrence of breast cancer. Results: Total 110 patients with breast cancer were recruited. Mean age of the patients was 43.56 ± 8.9 years. Recurrence of breast cancer was found in 25 (23%) cases. Total 11 (10%) patients belonged to age group <30 years followed by 13 (11.82%) patients to age group 30-40 years, 41 (37.27%) to age group 41-50 years and 45 (40.91%) patients to age group 51-60 years. Recurrence of breast cancer was noted in 2 (18.18%) patients, 3 (23.08%) patients, 10 (24.39%) patients and 10 (22.22%) patients respectively. Statistically insignificant association of recurrence with age group was noted with p value 0.9776. Conclusion: Results of this study showed a higher rate of recurrence of breast carcinoma after modified radical mastectomy. Most of the patients belonged to 5th decade of life. Parity, educational status and marital status showed no association with recurrence of breast cancer.


2021 ◽  
Vol 15 (6) ◽  
pp. 1266-1268
Author(s):  
S. Aslam ◽  
M. Gondal ◽  
T. Tahira ◽  
Zille Huma ◽  
M. Mumtaz ◽  
...  

Background: The whole world is facing one of the biggest health related disasters of the century. As a novel disease, Covid-19 has so many parameters yet to explore. Aim: To explore varied pattern of clinical presentation of COVID-19 in obstetric population in tertiary care hospital. Study design: Cross-sectional study. Methodology: This study with enrolled pregnant females (n=36) was carried out after ethical review committee’s (ERC) approval at Department of Gynecology & Obstetrics, Sir Ganga Ram Hospital, Lahore-Pakistan over a period of 3 months in 2020. Data was analyzed by SPSS software, version-20. Presenting symptoms of subjects were presented as frequency and percentage. Results: Total 36 patients were selected. Twenty four (66.66%) patients were symptomatic while the rest 12 (33.33%) patients were asymptomatic. Conclusion: We concluded that clinical presentation of COVID-19 pregnant patients is similar as in rest of the world and it is also same as in general population. Keywords: Covid-19, Pregnant Patients and Clinical Presentation.


2021 ◽  
Vol 9 (10) ◽  
pp. 438-443
Author(s):  
Ragoor Sujatha ◽  
◽  
Mary Jayasheela ◽  
Karuna Bhavani ◽  
◽  
...  

A cross sectional studywas conducted over a period of 15 months from 1st Jan 2020 to 31st March 2021 at Malla Reddy Hospital,a tertiary care hospital. To study the incidence of fibroids according to FIGO categorization and their clinical presentation. 38 confirmed cases of fibroid uterus in the age group 20 – 60 attending gynecology OPD were interviewed and subjected to regular gynecological examination, PAP smear, dilatation and curettage procedures. Based on the studies, 60% of these patients were subjected to total abdominal hysterectomy as a part of treatment and the intra operative findings of the specimens were noted. The leiomyomas were classified according to the histopathological and ultrasonographic findings based on FIGO categorization. Highest incidence was seen 41 to 45 years age (52.6%). Incidence of Leiomyoma types according to FIGO subclassification system were found to be Type0=5%, Type1=5%, Type2=5%, Type3=13%, Type4=30%, Type5=13%, Type6=18.6%, Type7=3.3% and Type8=5%. Multiple fibroids were more common than single fibroids. Posterior location fibroids were more common than anterior. Most common symptom was menorrhagia (73.6%) followed by spasmodic dysmenorrhea (47.3%) and metrorrhagia (26.3%), infertility and symptoms of anemia. Most common sign was pallor (58%) followed by mass per abdomen (18.4%). Incidence of associated pathology of adenomyosis (18%) ovarian cysts (8%), endometrial polyps (8%), myxoid degeneration (2.6%). The results of our study matched the existing studies.


2021 ◽  
Vol 71 (5) ◽  
pp. 1787-90
Author(s):  
Uzma Naz Shaikh ◽  
Muhammad Ali Ghoto ◽  
Abdullah Dayo ◽  
Mudassar Iqbal Arain ◽  
Jibran Khan

Objective: To find out the frequency of anemia, agranulocytosis and thrombocytopenia in hyperthyroid patients after the use of propylthiouracil. Study Design: Cross sectional study. Place and Duration of Study: Out Door Patients Department and Pathology Laboratory in Liaquat University Medical & Health Sciences, Hospital Hyderabad/Jamshoro, from May 2016 to Apr 2017. Methodology: Two hundred cases, comprising of adult patients were categorized into five groups, age group 15-30 years 79 (39.5%) patients presenting the highest out of total, age group 31-45 years 68 (34%) patients, age group 46-60 years 36 (18%), age group 61-75 years 14 (7%) patients, age group >75 years 3 (1.5) patients. Complete blood count was analyzed on Sysmex Kx21 and thyroid profiles were analyzed on Elecysis 2010 from the Pathology Department. SPSS version 22 was used for data analysis. Result: Out of total patients, 32 (16%) were males and 168 (84%) were females with mean age of 37.44 ± 14.82 years. Majority of patients 68 (34%) were anemic, while 4 (2%) had agranulocytosis and 11 (5.5%) had thrombocytopenia. Headache was reported in 111 (55.5%), exophthalmos in 106 (53%), sore throat in 172 (86%), fever in 136 (68%) and weight loss in 95 (47.5%) patients. Conclusion: Propylthiouracil causes defective hematopoiesis in hyperthyroid patients because propylthiouracil has adverse suppressive effects on bone marrow.


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