scholarly journals Clinical, laboratory and instrumental indicators in patients who have undergone COVID-19

2021 ◽  
Vol 5 (3) ◽  
pp. 403-415
Author(s):  
Muso Urinov ◽  
Nigora Alikulova ◽  
Dilfuza Zukhritdinova ◽  
Mekhriddin Usmonov ◽  
Rakhimjon Urinov
Keyword(s):  
Clinical Laboratory ◽  
Reference Interval ◽  
The Elderly ◽  
Neurological Complications ◽  
Middle Aged ◽  
Coagulation Activity ◽  
Female Patients ◽  
Aged People ◽  
Male Patients ◽  
Coronavirus Infection

280 patients with COVID-19 were examined (average age 53.9±8.1 years; gender index 1.37:1.0 (162 men and 118 women). It was revealed that young people (especially women) were more common with a mild course of the disease (64.2%), middle – aged people-with a moderate-severe variant of COVID-19 (54.8%), In the group of patients with a severe course of coronavirus infection, female patients prevailed among the elderly, and among middle –aged men – 47.8% and 48.4%, respectively. The comorbid background before the disease CAVID-19 and the neurological complications that appeared on the background of CAVID-19 in the percentage ratio prevailed in males. There were no significant differences in the frequency of complications from the severity of the COVID-19 disease. It was revealed that at the time of hospitalization, all the studied markers of coagulation activity were changed and statistically significantly differed from the reference interval, which indicated the activation of the procoagulation potential. In the group of female patients, these indicators were more pronounced. CT examination revealed that the percentage of damage to both lungs was significantly higher in female patients compared to male patients.

Complex treatment of periodontitis: patient’s reaction to the therapy

2020 ◽  
Vol 25 (2) ◽  
pp. 97-100
Author(s):  
A. K. Iordanishvili ◽  
V. A. Guk ◽  
A. A. Golovko
Keyword(s):  
Elderly People ◽  
Periodontal Diseases ◽  
Personal Characteristics ◽  
The Elderly ◽  
Comprehensive Treatment ◽  
Complex Treatment ◽  
Middle Aged ◽  
Aged People ◽  
Dental Rehabilitation ◽  
Success Of Treatment

Relevance. The success of treatment of periodontal diseases directly depends on the patient’s response to the therapy, therefore, the characteristics of the person’s personal characteristics can affect both the effectiveness of treatment and the prevention of relapse of the disease.Purpose. To study the features of the internal picture of the disease in the process of complex treatment of adult patients suffering from chronic generalized periodontitis.Materials and methods. The generally accepted comprehensive treatment of chronic generalized periodontitis in 69 middle-aged and elderly men was carried out taking into account the personal response of patients Solovyov «Psychosensory-anatomical-functional maladaptation syndrome».Results. When patients were discharged from the hospital, there was a difference in the phenomena of maladaptation among the elderly and middle-aged: in middle-aged people, sufficient adaptation to the conditions of existence was determined; in elderly people, due to the existing comorbid pathology, a state of maladaptation was diagnosed, which was caused by the presence of complaints of defects in the dentition.Conclusion. In elderly people, as soon as possible after completion of treatment in a hospital, dental rehabilitation cannot be considered completed, which requires the adoption of organizational measures for their timely provision of dentures.

信仰與斷裂——山中村祭祀圈的變遷與村民的奉祀理解

2021 ◽  
Vol 19 (1) ◽  
pp. 083-114
Author(s):  
楊國柱 楊國柱 ◽  
吳金奇 Yang, Kuo-Chu
Keyword(s):  
Local Community ◽  
Health And Safety ◽  
Belief System ◽  
The Elderly ◽  
Middle Aged ◽  
Aged People ◽  
Mountain Village ◽  
Field Investigations ◽  
Meaning Interpretation ◽  
The Village

<p>嘉義縣民雄鄉山中村1（舊稱牛斗山或牛稠山），因牛稠溪域流經村莊而得此名，早期是全鄉人口最大村。山中村宗教信仰普遍為民間信仰，村莊主廟為廣濟宮，以奉祀池府王爺、媽祖、鄭成功為主，但村莊發展及信仰主體係圍繞池府王爺。本文採用文獻分析、田野調查及立意取樣後進行深度訪談，以探討山中村祭祀圈之形成，以及村民如何理解不同神靈之內涵，進而有助於山中村之社區發展與文化資源保存。</p> <p>藉由祭祀圈概念切入，以理解山中村社區各神靈祭祀圈的範圍與分布，進而探討地方社區信仰中心發展，與山中村民對不同神靈認知及意義之解讀。經研究發現：（一）隨著人口增加及集居地擴大，主廟的祭祀圈變大；由於廟務活動增加，牛斗山土地公廟的祭祀圈擴大；五營中的東、西兩營，未隨著社區的新增而往外遷移，因此祭祀圈無明顯變化。（二）山中村神靈祭祀圈的分布，「五營」與居民輪祀居住的地理範圍有關，原具有分群概念的輪祀傳統逐漸模糊：老者對此模糊；中年人認知些許；青年則不明白為何奉祀，宗教信仰傳承出現斷層的可能。（三）山中村民對不同祭祀圈神靈解讀有所異同，普遍難闡述神靈的由來及背景，較理解者屬老年人；其次為中年人；青年人則對神靈認知不清楚。（四）不同祭祀圈神靈意義與山中村民早期生活環境較有其關聯性，老年人多數提及身體健康及平安；中年人求財運、事業；青年人求課業順利。據此，就結論提出建議以供參考。</p> <p>&nbsp;</p><p>Shanzhong Village (formerly known as Niudou Mountain or Niuhou Mountain) in Minxiong Township, Chiayi County, got its name because the Niuhou Stream passed through the village. In the early days, it was the village with the largest population in the township. For the Guangji Palace, it is mainly dedicated to the worship of Lord Chifu, Mazu and Zheng Chenggong (Cheng Ch&rsquo;eng-Kung), but the village development and belief system surrounds Lord Chifu. This paper uses literature analysis, field investigations, and intentional sampling to conduct in-depth interviews to discuss the formation of the mountain village sacrificial circle and how the villagers understand the connotation of different gods, which can help the community development and cultural resource preservation of the mountain village. </p> <p> Through research, the concept of the religious field was cut in to understand the scope and distribution of the religious fields of the various deities in the Shanzhong Village community, and to discuss the development of local community faith centers and the understanding and meaning interpretation of the different deities of the Shanzhong villagers. The research found: (1) The religious realms become bigger because the population of village was increased；on the other side, Shanshang Viallage&rsquo;s religious realms become wilder due to the increase of temple actives. However, for the &quot;five camps&quot;, the east and west side of the deities&rsquo;s emissary did not extend so the Religious Realms can not protect the new village, (2) The distribution of the spiritual field in the Shanzhong village, the &quot;&quot;five camps&quot;&quot; are more closely related to the geographical scope of the residents&rsquo; rotation worship. The tradition of rotation worship with the concept of grouping is gradually blurring, and the old people are blurring; Understand why there is a possibility that there is a fault in the inheritance of religious beliefs; (3) Villagers in the mountains have different interpretations of deities in different religious fields, and it is generally difficult to understand the origin and background of deities, older than those who understand; older than middle-aged; more young Unrecognizable to the gods; (4) The significance of the gods in different religious fields is more related to the early life environment of the villagers in the mountains. The elderly have significant health and safety; the middle-aged people seek wealth and career; the young people seek smooth schooling .Then refer to the above research results to make research suggestions.</p> <p>&nbsp;</p>

Cerebrovascular complications of novel coronavirus infection in young and middle-aged people

2021 ◽  
pp. 21-25
Author(s):  
F. Z. Olimova ◽  
Ye. G. Klocheva ◽  
S. V. Lobzin ◽  
V. V. Goldobin ◽  
M. S. Partavi
Keyword(s):  
Blood Coagulation ◽  
Genetic Factors ◽  
Cerebrovascular Disorders ◽  
Coagulation System ◽  
The Novel ◽  
Middle Aged ◽  
Aged People ◽  
Cerebrovascular Complications ◽  
Coronavirus Infection ◽  
Novel Coronavirus

The novel coronavirus (SARS‑CoV‑2) infection manifested by a pandemic and has a wide range of complications, including the nervous system’s complications. Despite the fact that older people with comorbidities are more at risk of developing complications from the sequelae of previous COVID‑19 disease, a significant link between the novel coronavirus infection and cerebrovascular disorders in young and middle‑aged people is increasingly mentioned in the literature. The development of cerebrovascular complications in these people not only depends on the damaging effect of the novel coronavirus infection on the macroorganism, but also on a number of other factors, in particular, on the genetic factors of the blood coagulation system. Further study of the possible influence the novel coronavirus infection on the development of cerebrovascular complications, taking into account the genetic factors of the blood coagulation system in young and middle‑aged people will provide early prevention and timely correction of cerebrovascular disorders.

scholarly journals The Influence of the Interface Button Design of Touch Screens on Operation and Interpretation by Elderly and Middle-Aged Adults

Designs ◽  
2019 ◽  
Vol 3 (3) ◽  
pp. 35
Author(s):  
Yeh Po-Chan
Keyword(s):  
Elderly People ◽  
The Elderly ◽  
Middle Aged ◽  
Aged People ◽  
Display Position ◽  
Ideal Image ◽  
Self Testing ◽  
Middle Aged Adults ◽  
Good Interpretation ◽  
The Ideal

Body function begins to decline in middle age, with changes becoming increasingly noticeable over time. With the popularization of educational and information technology, people know more about healthcare and are becoming accustomed to self-testing using health equipment. Technological changes are reflected in products, which present innovations including the switch from traditional to touch-controlled interface designs. This can cause difficulties in the interpretation and interface operation for older adults, who may be facing physiological and psychological alterations. Understanding users’ physiological limitations has become an important aspect of product design. This study explored the effects of physiological limitations on touch-screen operation in middle-aged and elderly people, specifically regarding button type, display position, and button size. A total of 64 participants were included in the study: 32 middle-aged people (aged 45–64 years) and 32 elderly people (65 years of age and older). Each participant was asked to complete 32 tasks (two button categories × four button sizes × four presentation positions). The results revealed no differences between the elderly and the middle-aged groups with regard to the interpretation of image buttons and text buttons; however, button size affected the operation and interpretation time. Middle-aged participants demonstrated good interpretation performance when the buttons were displayed in the upper or lower part of the screen, whereas elderly participants only had a good interpretation performance when the buttons were in the upper part. For both groups, the ideal image button size was 16 mm with a text font size of 22.

scholarly journals Characteristics of Presbycusis in A Super-Aged Society

2021 ◽  
Vol 6 (2) ◽  
Author(s):  
Hajime Sano
Keyword(s):  
Hearing Loss ◽  
High Frequency ◽  
Pure Tone ◽  
The Elderly ◽  
Elderly Group ◽  
Hearing Level ◽  
Speech Discrimination ◽  
Frequency Range ◽  
Female Patients ◽  
Male Patients

Objectives: To estimate presbycusis' characteristics and investigate whether any changes have occurred in the pathophysiology of presbycusis over the decades. Methods: This was a retrospective cross-sectional observational study. A total of 186 patients aged ≥ 65 years were selected for the elderly group; they included patients with mild-to-moderate sensorineural hearing loss of unknown cause. For the middle age group, 56 patients aged 30–50 years who had positive results for the recruitment phenomenon were selected as controls. The participants’ age, sex, pure-tone hearing levels of air conduction (125–8000 Hz), maximum speech discrimination score (SDSmax), and the presence or absence of the recruitment phenomenon were investigated based on medical records. Results: Sixty-one patients in the elderly group were aged ≥ 80 years. Hearing levels were significantly better in male patients in the low-frequency range and significantly better in female patients in the high-frequency range (p < 0.01). In the elderly group, the proportion of patients with poor speech discrimination was 52.4–70.2%. The SDSmax was significantly higher in female patients than in male patients (p < 0.01). The proportion of patients with the recruitment phenomenon was 93.5%. The audiometric hearing pattern was dominated by a gradual-down slope, high-frequency-impaired, and flat patterns. There were significantly more female patients with a flat pattern and significantly more male patients with a gradual-downslope pattern and U-shaped pattern (p < 0.01). Age, sex, mean pure-tone hearing level, and audiometric hearing pattern significantly affected the SDSmax (all, p < 0.05), as evaluated with multiple regression analysis. Conclusion: More than half of the elderly patients with mild or moderate hearing loss were estimated to have retrocochlear damage. The age of hospital visitors for presbycusis was found to have increased over time. However, the distribution of pathophysiologies was not different from that in previous studies performed with relatively younger patients. This suggests a shift of patients presenting with presbycusis toward an older age range.

Abstract 17228: Gender Differences in Treatment and Outcomes of Patients With COVID-19 Respiratory Failure

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Rafey A Feroze ◽  
Tariq Azam ◽  
Husam Shadid ◽  
Michael Pan ◽  
Hanna Berlin ◽  
...  
Keyword(s):  
Gender Differences ◽  
Mechanical Ventilation ◽  
Length Of Stay ◽  
Clinical Laboratory ◽  
Ventilatory Support ◽  
Hospital Length Of Stay ◽  
Hospital Death ◽  
Female Patients ◽  
Severity Of Disease ◽  
Male Patients

Introduction: The COVID-19 pandemic has spread across the globe and claimed many lives. Initial studies suggest that there are gender-based differences in severity of disease and mortality, with male patients having worse outcomes. We sought to further characterize gender differences to COVID-19 infection. Hypothesis: Male patients have a higher severity of illness from COVID-19. Methods: The Michigan Medicine COVID-19 Cohort (M2C2) is an ongoing prospective observational study in which detailed clinical, laboratory and outcomes data were collected from chart review of consecutive adult patients hospitalized for COVID-19. Patients who were positive for SARS-CoV-2 infection but without symptoms of COVID-19 were not included in this cohort. The M2C2registry consists of 553 patients with 491 included in this analysis. There were 282 male patients and 208 female patients. Baseline characteristics, comorbidities, and characteristics of in-patient management were compared among male and female patients. The primary outcomes analyzed were in-hospital death of any cause including dismissal to hospice, need for renal replacement therapy (RRT), need for mechanical ventilation, and hospital length of stay. Results: Significant differences were observed among various patient characteristics and outcomes across gender. While no mortality difference was present between males and females, 43.8% of male patients were diagnosed with ARDS compared to 35.1% of female patients. The average days on mechanical ventilation were greater for male ICU patients (4.1 ± 5.91 vs. 3.4 ± 5.75) and the length of stay (days) was also longer for males (13.6 ± 11.94 vs. 12.2 ± 12.29). Admission creatinine was higher in males compared to females (2.95 ± 12.97 vs. 1.31 ± 1.33) and more male patients required RRT during their ICU admission (19.5% vs. 10.6%). Conclusions: While no difference in in hospital mortality was observed across gender, the severity of disease was greater among male patients in regards to ARDS, the need for ventilatory support, and kidney injury with requirement for RRT.

scholarly journals Attitudes to Death of Middle-Aged in the Context of the COVID-19 Pandemic

2020 ◽  
Keyword(s):  
Physical World ◽  
Middle Aged ◽  
Attitude To Death ◽  
Psychological Study ◽  
Life After Death ◽  
Aged People ◽  
Attitude Towards Death ◽  
Coronavirus Infection ◽  
Main Thing ◽  
Second Wave

Psychological aspects of the attitude to death in the conditions of the COVID-19 pandemic are considered. The results of the research characterizing the attitude to death in different countries of the world during coronavirus infection are presented. The results of an empirical psychological study of the Ukrainian medieval group during the "first wave" of COVID-19 are presented. The attitude of people of the studied Ukrainian middle-aged group to the phenomenon of death in the conditions of the COVID-19 pandemic is ambivalent with a predominance of negative character. For middle-aged people, thoughts about death are not the main thing, thoughts about their own death are ambivalent, and the level of stress resistance associated with thoughts about death is average. People are afraid, in particular, not of death itself and the cessation of its existence, but of the difficult and painful process of dying. It was determined that the attitude to death is related to thoughts about their own death in the study group. An optimistic attitude towards death is associated with positive thoughts about one's own death. The problems of faith in life after death, as well as the influence of religiosity on the fear of death are considered. The presence of more positive metaphors about death, belief in life after death, the possibility of reunion with relatives, wisdom and forgiveness have led to significant differences in the results between groups of believers and atheists. The atheists studied, who are frightened by the loss of the physical world in the phenomenon of death, who imagine earthly life as the only one and believe that those who die feel fear and hopelessness before death, more often chose negative metaphors about their own death. Significant differences were identified between thoughts of death in women and men. Women, unlike men, have more pessimistic thoughts about the phenomenon of death. Women more often than men consider that thinking about death is outrageous and indicate that thoughts of death frighten and traumatize them. Thus, in the spring and summer of 2020, no significant impact of COVID-19 on the anxiety of middle-aged Ukrainians about death was identified. The situation of the second wave of coronavirus infection and the expected third (in early 2021) requires further research on the phenomenon of death in this age group.

The role of inflammation in the development of post-stroke depression in elderly patients

2022 ◽  
pp. 841-847
Author(s):  
О.А. Осипова ◽  
Н.И. Клюшников ◽  
Е.В. Гостева ◽  
О.Н. Белоусова ◽  
Н.И. Жернакова ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Elderly Patients ◽  
Middle Age ◽  
The Elderly ◽  
Middle Aged ◽  
Post Stroke ◽  
Aged People ◽  
Tnf Α ◽  
Post Stroke Depression

Цель исследования - изучение роли цитокинов, соотношения нейтрофилов и лимфоцитов в развитии постинсультной депрессии (ПД) у больных пожилого возраста. В исследование были включены 110 больных с острым ишемическим инсультом, из них 60 человек среднего возраста (52±5 лет) и 50 - пожилого возраста (66±4 года). Контрольную группу составили 20 человек среднего возраста без инсульта в анамнезе. Через 3 мес наблюдения ПД в пожилом возрасте развилась у 28 (56 %) больных, в среднем возрасте - у 26 (43,3 %). Больные пожилого возраста с ишемическим инсультом, у которых развилась ПД, были достоверно старше (7,9 %, р<0,05), чаще имели артериальную гипертензию (12,4 %, р<0,05), уровень гликемии выше на 16,1 % (р<0,05), триглицеридов - на 14 % (р<0,05), ЛПНП - на 12,8 % (р<0,05). Больные среднего возраста с ПД имели ИМТ выше на 8,1 % (р<0,05), уровень гликемии - на 9,6 % (р<0,05), триглицеридов - на 10,9 % (р<0,05), ЛПНП - на 9,7 % (р<0,05), чем больные без депрессии. Пожилые больные с ишемическим инсультом и ПД имели более высокий уровень цитокинов - IL-1β был выше на 35,4 % (р<0,01), TNF-α - на 27 % (р<0,01), INF-γ - на 18 % (р<0,01), чем у больных без ПД. У больных пожилого возраста с ПД соотношение нейтрофилов и лимфоцитов (Н/Л) было на 46 % (p<0,001) выше, чем у больных без ПД. В группе больных пожилого возраста при наличии ПД соотношение Н/Л было на 50 % (p<0,001) выше, чем в аналогичной группе среднего возраста. Таким образом, у пожилых больных с ишемическим инсультом уровень маркеров воспаления может иметь прогностическое значение в развитии постинсультной депрессии. The aim of the study was to study the role of cytokines, the ratio of neutrophils and lymphocytes in the development of post-stroke depression in elderly patients. The study included 110 patients with acute ischemic stroke, including 60 middle-aged people (52±5 years) and 50 elderly people (66±4 years). The control group consisted of 20 middle-aged people without a history of stroke. After 3 months of follow-up, post-stroke depression (PSD) developed in the elderly in 28 patients (56 %), in the middle age in 26 patients (43,3 %). Patients with ischemic stroke in the elderly who developed PSD were significantly older (7,9 %, p<0,05), more often had arterial hypertension (12,4 %, p<0,05), the level of glucose was 16,1 % higher (p<0,05), triglycerides by 14 % (p<0,05), LDL-C by 12,8 % (p<0,05). In middle age, patients with post-stroke depression had a body mass index higher by 8,1 % (p<0,05), a glucose level by 9,6 % (p<0,05), triglycerides by 10,9 % (p<0,05), LDL-C by 9,7 % (p<0,05) than patients without PSD. Elderly patients with ischemic stroke and PSD had higher levels of cytokines - IL-1β was 35,4 % higher (p<0,01), TNF-α by 27 % (p<0,01), INF-γ by 18 % (p<0,01) than in patients without PSD. In elderly patients with PSD, the ratio of neutrophils and lymphocytes (N/L) is 46 % (p<0,001) higher than in patients without PSD. In the elderly, in the presence of PSD, the N/L ratio was 50 % (p<0,001) higher than in the same middle-aged group. Thus, in elderly patients with ischemic stroke, the level of inflammatory markers may have a prognostic value in the development of post-stroke depression.

scholarly journals Middle-aged people and the elderly have the similar risk of death from Covid-19: considering background mortality

2020 ◽  
Author(s):  
ZHONGNENG XU
Keyword(s):  
Elderly People ◽  
Age Distribution ◽  
The Elderly ◽  
Natural Mortality ◽  
Middle Aged ◽  
Death Risk ◽  
Aged People ◽  
Risk Of Death ◽  
Background Mortality ◽  
Similar Risk

In USA, middle-aged people might be evaluated as having a low risk of Covid-19 death, but if the natural mortality is considered, the age distribution of death risk from Covid-19 changes. The proportions of Covid-19 deaths in total deaths among middle-aged and elderly people are in the same cluster. This shows that the increase rates in deaths caused by Covid-19 to middle-aged people is similar to that of the elderly, and it is necessary to pay the same attention to the risk of Covid-19 death in middle-aged people.

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