scholarly journals Potential Bioactive Compound Seaweed Halimeda micronesica and Halimeda macroloba as Antioxidant and Phytochemical Screening of Active Seaweed Extracts from Maspari Island

Author(s):  
Muhammad Hendri ◽  
Oktaviana Lubis Delini ◽  
Rozirwan Rozirwan
2016 ◽  
Vol 3 (1) ◽  
pp. 37-45 ◽  
Author(s):  
Fakhruddin Ali Ahmed ◽  
Anisur Rahman ◽  
Sanzida Mubassara

Blumea lacera collected from JU campus and the Sundarbans showed strong presence of carbohydrates, flavonoids, trace amount of alkaloids, weak presence of some glucosides, terpenoids and steroids following preliminary phytochemical screening. DPPH free radical scavenging activity increased with the increase of concentration of methanol, ethyl acetate and n-hexane fractions of both the samples. Methanol and ethyl acetate fractions of JU sample showed strong scavenging activity of DPPH free radical. Concentration dependent increment in percent mortality of brine shrimp nauplii was observed in all the fractions of both the samples. Ethyl acetate and methanol fractions of JU sample showed less cytotoxicity than that of Sundarbans samples. Therefore, methanol and ethyl acetate fractions of JU sample should be the choice to identify new bioactive compound(s) in the future.Jahangirnagar University J. Biol. Sci. 3(1): 37-45, 2014 (June)


2020 ◽  
Vol 11 (2) ◽  
pp. 289-299
Author(s):  
Mishra D N ◽  
Gomare K S ◽  
Sheelwant S V

Indigofera tinctoria (Linn.), a perennial shrub belongs to the family Fabaceae (Leguminosae) is well known in Indian system of medicines for its traditional uses. The present study was carried to find out the possible bioactive components in the leaves of this plant in ethanol extract by Gas Chromatography-Mass Spectrometry (GC-MS) analysis and the therapeutic uses of each compound as per PASS and other database. The mass spectra of the extract found compounds that were matched with the National Institute of Standards and Technology (NIST version 5.7.1) library database. The GC-MS study observed different peaks as per retention time and then those peaks were analysed determining presence of 26 phytochemical compounds. The qualitative phytochemical screening done by routine laboratory methods also indicated presence of these bioactive compound groups like alkaloids, flavonoids, tannins and phenols, saponins, glycosides and terpenoids. These 26 compounds are understood to have different therapeutic activities as per in-silico databases, e.g. 2-Acetylamino-3-hydroxy-propionoic acid (glutamic acid) - used as Anti-diarrheal, Antiviral, Antipyretic, Protein synthesis inhibitor, Antidiabetic, Non-steroidal, Anti-inflammatory agent, Antipsoriatic, Antioxidant, Antifungal, Antineoplastic (sarcoma), Antiparasitic, Antibiotic Aminoglycoside-like, Antiseborrheic,  Anticataract, Antithyroid, Anticarcinogenic, Antileprosy, Hair growth stimulant, Lipoprotein lipase inhibitor, Dermatologic, Testosterone, Antituberculosic, Antirickettsial, Antianemic, etc. activities. Hence, Indigofera tinctoria is an excellent source of phytocompounds, which help to heal various diseases and health complications in human beings. The use of this plant in traditional methods for the treatment of such diseases appears scientifically relevant as per the therapeutic activity data of its bioactive compounds.


2021 ◽  

Vasaka or Adhatoda vasica (L.) Nees is a well-known plant medication in Ayurvedic and Unani medicine. Cough, whooping cough, cold, and clinging phlegm in the mouth, throat, chest, or breast have been traditionally treated using Adhatoda vasica nees. The present study aimed to evaluate Adhatoda vasica's phytochemical analysis and antimicrobial activity. The preliminary phytochemical screening of alkaloids, steroids, saponins, phenols, and terpenoid yielded positive results. The antibacterial activity of ethanol and leaf extracts of Adhatoda vasica was investigated in this study. Based on the data presented herein, the largest zone of inhibition was found to be against Pseudomonas aeruginosa. The antifungal activity of Aspergillus clavatus was proven to have the maximum zone of inhibition. As a result, the current method may be effective in identifying new bioactive compound for the development of novel medications. Thus, it may be used as a strong antimicrobial agent against Pseudomonas aeruginosa pathogens.


2021 ◽  
Vol 13 (2) ◽  
pp. 313
Author(s):  
Dyahruri Sanjayasari ◽  
Maria Dyah Nur Meinita ◽  
Tjahjo Winanto

Highlight ResearchThe qualitative bioactive assay on terpenoid compound of six macroalgae species were tested.The effect of six macroalgae extracts as inducer mediating settlement to juvenile Perna viridis were observed.Three macroalgae species were potentially promote the retention of juvenile P. viridisAbstractThe low retention of juvenile of green mussels (Perna viridis) in the aquaculture holding system has become a constraint for its production. The depress number of juvenile mussel on the collector rope might be caused due to both limited spawning season and their secondary settlement behaviour. Therefore, providing suitable substrate which able to improve green mussel seed retention is required. One of the solutions is by applying inducer mediating settlement as substrate enrichment in order to optimize the retention of juvenile P. viridis. The potential substrates thought to have these inductive activities is seaweed. Seaweed bioactive compound which may improve juvenile mussel retention is terpenoid. Six seaweed extracts used in the current study and the terpenoid of these six macroalgae species were tested. Qualitatively all six seaweed showed a positive result on the terpenoid compound. The retention and survival of juvenile green mussel observed by using 20 conical tanks with a complete randomized design experiment. Each of the seaweed species tested separately comparing with three other experimental treatments under 24 h observation time, A (rope), B (rope + PhytagelTM), C (rope + PhytagelTM l+ solvent), D (rope + PhytagelTM + seaweed extract), it made four experimental treatments with 5 times replications. The result indicated a variation pattern on the retention of juvenile mussels according to the experimental substrate. The juvenile mussels were preferably settled on enriched substrate of G. latifolium and S. polycystum, extracts (p<0.05). Adding seaweed extracts on the substrate did not affect the mussels survival (p>0.05).


Author(s):  
M. Emmanuel ◽  
A. J. Dadah ◽  
A. A. Orukotan ◽  
J. Abbah ◽  
I. E. Aigbogun

The phytochemical screening of Terminalia avicennoids was carried out using qualitative method to determine the bioactive compounds present in the plant root, stem and leave extracts. Cooled Maceration method was used for the extraction.  Hundred grams (100 g) of each powder was soaked in 1000 ml of distilled water, allowed to stand for 5 hours.  The suspension was agitated after 30 minutes. The filtrate was thereafter separated from residue using No. 1 Whatman filter paper and concentrated using rotary evaporator. The crude extracts were separately kept in a screw capped bottle for further research. The bioactive compound in the plants were detected using AOAC method. The result revealed that alkaloid, flavonoid, tannin, saponins, phenol and glycoside were detected in the plants while steroid was not detected in the plants. Therefore, the presence of these phytocompounds is an indicative that the plant is medicinal and it can be used for the treatment of bacterial and fungal infections.


2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Nurpen Meitei Thangjam ◽  
Jasmina Taijong ◽  
Awadhesh Kumar

Abstract Background Artemisia vulgaris commonly known as “mugwort” is a very important medicinal plant which is used widely for the treatment of various ailments traditionally. The present studies aimed to conduct preliminary phytochemical screening and evaluate antioxidants and analgesic activities of leaves extract. Results Phytochemical screening showed the presence of saponins, glycosides, flavanoids, protein, triterpenoids in leaves extract. In DPPH, percentage inhibition of the scavenging activity (68.06%) by the extract in comparison with ascorbic acid (93.53%) at 60 μg/ml while in reducing power assay, the result shown the reducing power increases with the increase of concentration as (0.13 ± 0.02), (0.27 ± 0.03), (0.42 ± 0.03), (0.62 ± 0.05), (0.79 ± 0.02), (0.95 ± 0.05) at concentration of 5, 10, 15, 30, 60 and 100 μg/ml respectively. The evaluation of analgesic activities revealed that at the dose of 200 and 400 mg/kg of the extract showed significantly inhibited the writhing response induced by acetic acid by 8.60% and 32.03% comparatively with indomethacin at a dose of 10 mg/kg b. wt. exhibited 56.87% inhibition. Whereas, in the tail immersion methods, at the dose of 400 mg/kg b. wt. was showed higher deflexion value as 3.40 ± 0.300, while 200 mg/kg b. wt. was resulted at 2.90 ± 0.200 value in dose dependent manner at the maximum time of the studies (60 min). Comparatively, the reference drug indomethacin at dose 10 mg/kg b. wt. has shown the highest deflexion value (5.134 ± 0.351). Conclusion This finding concludes that the methanolic leaves extract has a potent antioxidants and analgesic activities and it could be attributed to the presence of flavonoids, triterpenoids, saponin, glycosides and proteins. A further study is required to find out the novel bioactive compound of Artemisia vulgaris L. which can lead more effective in various biological activities.


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