Evaluation of the effect of a biologically active additive from the lymphoid tissue of broiler chickens on cytotoxic activity and nonspecific resistance to infections

Author(s):  
N. A. Kol’berg ◽  
S. L. Tikhonov ◽  
N. V. Tikhonova ◽  
S. A. Leont’eva
2021 ◽  
Vol 935 (1) ◽  
pp. 012016
Author(s):  
N N Kuzmina ◽  
O Yu Petrov ◽  
V G Semenov ◽  
V V Boronin

Abstract Research is devoted to the study of the feasibility of using a natural antioxidant of plant origin as a biologically active additive to the basic diet and assessing the effectiveness of its use to increase the meat productivity of broiler chickens. In our work we examined the broiler chickens productivity and quality when using the drug ‘Dihydroquercetin’ (LLC’Kakhor’, Zima, Irkutsk region, Russia) in diets and established the amount of feed consumed and its costs per unit of production. Based on the studies, the addition of the preparation enables to increase the safety of broiler chickens by 20…30%, live mass - by 12…33%, mass of ripped carcass - by 15…38%, muscle tissue - by 3%, thoracic muscles - by 0.3…2%, and edible parts of carcass -by 2…6%. Moreover, the additive reduces the feed consumption by a head during the fattening period by an average of 46.09 g compared to the control.


Food Industry ◽  
2020 ◽  
Vol 5 (1) ◽  
pp. 58-64
Author(s):  
Andrey Vekovtsev ◽  
Tokhiriyon Boisjoni ◽  
Badarch Bayambaa ◽  
Victor Shelepov

The authors developed composition and innovative technology of a new specialized product in the form of a biologically active additive to normalize metabolic processes in the case of the musculoskeletal system damage. They obtained specialized product through innovative tableting technology providing high consumer properties, components preservation and its active principles. The technological solutions innovativeness enables to separate composition ingredients considering its chemical and pharmacological incompatibility, and to deliver it sequentially to various sections of the gastrointestinal tract at a given speed. Glucosamine sulfate as a part of the vitamin and mineral complex combining with minerals (micro- and macro-nutrients) – manganese sulfate, calcium hydroxyapatate, cholecoleceferol, zinc and magnesium oxides – have unidirectional functional properties related to the metabolism correction in case of the musculoskeletal system damage. Clinical investigations confirmed the vitamin and mineral complex effectiveness. The diet for children 8- 14 years old has included one capsule of the specialized product additionally three times a day. Children (3-7 years old) with the long tubular bones fracture have received one capsule twice a day. Authors tested the recipe and technological production parameters at the enterprises of the company “Artlife” under the conditions of international and domestic standards including GMP and guaranteeing the quality indicators and competitiveness stability.


Author(s):  
Ellada K. Рapunidi ◽  
◽  
Sergey Yu. Smolentsev ◽  
Galina S. Stepanova ◽  
Svetlana N. Savdur ◽  
...  

Author(s):  
S. M. Medvid

The article presents data on the influence of the complex of micro elements (Fe, Cu, Zn, Co, Mn) in the form of aquacitrate on the indices of non-specific and cellular immunity in chicken broilers. The poultry received a fodder, balanced by nutrients, according to its type, age and productivity. Control group of chickens were added standard mineral premix (SP) from inorganic compounds of bioelements. Broilers of experimental groups were given water with a complex mineral additive of aquacitrates. In particular, the chickens of the first experimental group – in the amount corresponding to their content in the standard premix (SP), and the 2nd, 3rd, 4th and 5th experimental groups – in the amount equal to 3/4, 1/2, 1/4 and 1/10 of the content of mineral elements in the standard premix. It was found that bactericidal and lysozyme activity of blood serum (BASB and LASB) were the highest in broiler chickens of the third and fourth experimental groups and exceeded the control values by 5.7 and 5.3%, respectively. In the bird of the second and fifth groups, the studied indicators were closer to the ones in control. However, in the chickens of the group D1, giving them the highest studied dose of aquacitrate of micor elements, the values of BASB and LASB tended to decrease. Concerning the level of CIC in serum, it was the highest in the chickens of the second, third and fourth groups, the lowest in the group D1. A similar pattern is also characteristic for phagocytic activity of pseudoiesinophils (PhA). The bite of half and even the quaternary amount of citrates of micro elements, compared with the amount of bioelements in inorganic form, provided an increase, compared to control, of PhA. At such a dose of micro elements in the nanoform in the blood of broilers, the number of T-total and T-active lymphocytes increased, including T-heeler cells and decreased the relative number of T-suppressors. The bird of the first experimental group was characterized by a decrease in the percentage of T-heeler against the background of a slight increase of T-suppressors. Thus, the results of studies of indices of nonspecific and cellular immunity suggest that micor elements in the nanodisperse form, due to better bioavailability and high bioactivity, have a positive effect on the formation and development of the immune system in broiler chickens at a dose corresponding to 25 and 50%, from recommended quantity of biometals in the standard premix.


Author(s):  
S. A. Shpуnova ◽  
O. A. Yadrishchenskaya ◽  
T. V. Selina ◽  
E. A. Basova

In order to increase the meat productivity of broiler chickens, increase production volumes and reduce the prime-cost of poultry products, it is necessary not only to ensure balanced feeding and compliance with production technology but also to include in the poultry diet non-traditional additives, biologically active substances that contribute to the normalization of metabolic processes and improve the digestibility of feed nutrients. One of these dietary additives is Betulin extracted from birch bark, which has antioxidant and immunomodulatory properties. In this regard, the purpose of the research was to study the influence of compound feed with the introduction of 2 % feed additive based on a synthetic microspherical nanoporous carbon carrier containing biologically active Betulin in its composition on the productivity of broilers. The results of studies on broiler chickens using compound feed with 2 % feed additive have been presented in the article. It has been found that the feed consumption per 1 kg of live weight gain in poultry of the experimental group have been lower by 9,5 % due to better absorption of nutrients, the live weight of broiler chickens of the experimental group at the age of 42 days was 2625,6 g and it was higher than the control group by 3,68 %. The digestibility of crude protein and fat reached 92,73 and 88,03 %, which exceeded the control group by 1,03 and 3,03 abs.%, respectively. It has been found that the use of compound feed with 2 % of the feed additive with the biologically active substance is of practical importance in connection with the increase in the productivity of broilers and the level of profitability of meat production by 8,2 abs.%.


Author(s):  
B. S. Kaloev ◽  
M. O. Ibragimov ◽  
M. M. Shagaipov

The reliability of the results obtained in scientific and economic experiments on the study of the effectiveness of the use of various feed components, including biologically active substances in the rearing of broilers needs to be confi rmed in production conditions. The purpose of the research was to study the joint use of enzyme drugs and lecithin in the rearing of broiler chickens. The results of production experiment on the study of the effectiveness of the joint inclusion of enzyme drugs Sunzyme and Sunfyse 5000 as well as lecithin in the diet of broiler chickens of the cross Ross-308 have been presented in the article. Production tests have been carried out under the conditions of the breeding farm “Achkhoy– Martanovsky” in the Chechen Republic. The duration of the experiment was 45 days. For research on the principle of analog groups two groups have been formed: a control group and an experimental group of 1000 heads in each. The broilers of the control group have been fed compound feed prepared in accordance with the growing period and consisting mainly of grain components of local production. The broilers of the experimental group have been fed the same compound feed, but with the addition of two enzyme drugs Sanzyme and Sanfyse 5000 (100 g/t of feed) as well as lecithin (10 g/kg of feed). The results of the production experiment fully confi rmed the data obtained in the scientific and economic experiment. The positive effect of the joint use of the studied enzyme drugs and lecithin has been manifested in all the studied productive traits. In particular, the increase in live weight of broilers increased by 12,1 %, slaughter yield by 3,5 %, the yield of carcasses of the 1st category by 3,0 %. The main economic indicators also found their confirmation: feed consumption per unit of growth decreased by 11,7 %, additional profit was received in the amount of 27308,2 rubles, the level of profitability of broiler rearing increased by 18,4 %.


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