Investigation and analysis of the status of clinical research coordinators

2020 ◽  
Vol 20 (5) ◽  
pp. 350-354
Author(s):  
Yu FENG ◽  
◽  
Lin RAO ◽  
Jie QIAO
Keyword(s):  
Clinical Research ◽  
Medical Science ◽  
Educational Background ◽  
Management Mode ◽  
Current Status ◽  
Cancer Center ◽  
Current Management ◽  
Long Run ◽  
Clinical Research Coordinators ◽  
The Status

Objective： To investigate the current status of clinical research coordinators（CRCs） in Fudan University Shanghai Cancer Center，so as to optimize the current management mode and improve the quality of drug clinical trials.Methods： A survey was made among 104 CRCs in the hospital by using a self-made questionnaire，which included professional background，problems facing CRCs and their opinions or suggestions concerning the current management mode.Finally，the study made a descriptive statistical analysis of the obtained results.Results and Conclusion： Most of the CRCs in the hospital had an educational background of above undergraduate course in related medical science，over 80% of them had service years of less than 3 years，and less than 50% of them used to undertake clinical trials independently before they took up their posts in the hospital.The majority of the CRCs had a love for their profession and a sense of accomplishment，but only 20% of them had a sense of home-coming and approval.The feelings of heavy workload and dissatisfaction with salary widely existed among CRCs.Poor cooperation between subjects and pharmacy intravenous admixture service（PIVAS） and CRCs occasionally occurred in work.CRCs put forward a series of suggestions on the current CRCs management mode in the hospital.Such measures as setting up CRCs access threshold，raising salary，enriching training contents，reforming the work system of PIVAS，enhancing the sense of responsibility of clinical researchers，and holding regular informal discussions should be taken to intensify the construction of the CRCs team both professionally and from the aspect of team stability in the long run.

Towards sustainable sludge management in Poland: the current status and perspectives

2007 ◽  
Vol 2 (1) ◽  
Author(s):  
G. Malina ◽  
J.D. Bien ◽  
B. Bien
Keyword(s):  
Sewage Sludge ◽  
Management Practices ◽  
Current Status ◽  
Sludge Management ◽  
Current Management ◽  
Institutional Issues ◽  
The Status ◽  
Sewage Sludge Management

The status of sewage sludge management in Poland is presented. Current management practices are reviewed, and the problems associated with them evaluated, including technological aspects, as well as institutional issues, such as enforcement of legislation and problems with utilization. Perspectives for more sustainable sludge management practices are outlined and briefly discussed.

scholarly journals Pediatric surgical services in Bangladesh during the COVID 19 pandemic: How they are affected and how to overcome the backlog, keeping healthcare professionals safe.

2020 ◽  
Author(s):  
Md Jafrul Hannan ◽  
Mosammat Kohinoor Parveen ◽  
Md Samiul Hasan
Keyword(s):  
Surgical Procedures ◽  
Pediatric Surgery ◽  
Emergency Services ◽  
World Health ◽  
Current Status ◽  
Public And Private ◽  
Elective Surgical Procedures ◽  
Long Run ◽  
The Status ◽  
The Government

Background: Severe Acute Respiratory syndrome coronavirus 2 (SARS-CoV-2), which originated in Wuhan, China, has turned into a pandemic. All countries have implemented multiple strategies to try mitigating the losses caused by this virus. To stop the rapid spread of the disease and in compliance with the World Health Organizations social distancing policy, the government of Bangladesh has implemented a number of strategies, one of which is to limit the spread of the virus in hospitals by postponing elective procedures and providing only emergency services in the hospitals. The objective of this survey was to assess the current status of pediatric surgical procedures in different hospitals in Bangladesh and assess the effects of the current restrictions along with their implications in the long run. Materials and Methods: A survey was performed among doctors from public and private hospitals in Bangladesh to evaluate the status on pediatric surgery. Results: The results clearly revealed the lack of a significant reduction in doctors exposure to SARS-CoV-2 by postponing elective procedures. Conclusion: Keeping in mind the socioeconomic and health care conditions of the country, the author recommend resuming elective surgical procedures. Keywords: COVID 19, Pediatric surgery, Surgery during pandemic, Pediatric surgery in Bangladesh, COVID 19 and pediatric surgery.

scholarly journals The Current Status of Emergency Operations at a High-Volume Cancer Center

2014 ◽  
Vol 99 (6) ◽  
pp. 719-722 ◽  
Author(s):  
Koji Komori ◽  
Kenya Kimura ◽  
Takashi Kinoshita ◽  
Seiji Ito ◽  
Tetsuya Abe ◽  
...  
Keyword(s):  
Surgical Procedures ◽  
High Volume ◽  
Current Status ◽  
Cancer Center ◽  
Operative Death ◽  
Emergency Operations ◽  
Emergency Situations ◽  
Sufficient Detail ◽  
The Status ◽  
Clinical Conditions

Abstract This study aimed to assess the pathogenic causes, clinical conditions, surgical procedures, in-hospital mortality, and operative death associated with emergency operations at a high-volume cancer center. Although many reports have described the contents, operative procedures, and prognosis of elective surgeries in high-volume cancer centers, emergency operations have not been studied in sufficient detail. We retrospectively enrolled 28 consecutive patients who underwent emergency surgery. Cases involving operative complications were excluded. The following surgical procedures were performed during emergency operations: closure in 3 cases (10.7%), diversion in 22 cases (78.6%), ileus treatment in 2 cases (7.1%), and hemostasis in 1 case (3.6%). Closure alone was performed only once for peritonitis. Diversion was performed in 17 cases (77.3%) of peritonitis, 4 cases (18.2%) of stenosis of the gastrointestinal tract, and 1 case (4.5%) of bleeding. There was a significant overall difference (P = 0.001). The frequency of emergency operations was very low at a high-volume cancer center. However, the recent shift in treatment approaches toward nonoperative techniques may enhance the status of emergency surgical procedures. The results presented in this study will help prepare for emergency situations and resolve them as quickly and efficiently as possible.

Feasibility, Acceptability, and Preliminary Effectiveness of a Compassion-Centered Team Intervention to Improve Clinical Research Coordinator Resilience and Well-Being

2021 ◽  
pp. OP.21.00120
Author(s):  
Jennifer S. Mascaro ◽  
Patricia K. Palmer ◽  
Marcia J. Ash ◽  
Caroline Peacock ◽  
Anuja Sharma ◽  
...  
Keyword(s):  
Clinical Research ◽  
Well Being ◽  
Self Report ◽  
Comprehensive Cancer Center ◽  
Cancer Center ◽  
Clinical Research Coordinator ◽  
Individual Resilience ◽  
Clinical Research Coordinators ◽  
Research Coordinator ◽  
The Impact

PURPOSE: Oncology clinical research coordinators (CRCs) and team-based coordinator care are critical for the success of clinical trials. However, CRCs typically report elevated anxiety and burnout and many oncology centers have high levels of coordinator attrition. To address the need for a team-based intervention to reduce burnout and promote resilience and cohesion among CRCs, we developed a compassion-centered, team-based intervention, Compassion-Centered Spiritual Health Team Intervention (CCSH-TI). METHODS: Participants were CRCs working in disease-specific teams within a comprehensive cancer center. CRCs were randomly assigned by team to either participate in four 60-minute sessions of CCSH-TI or receive the intervention after the study. To evaluate whether CCSH-TI is feasible and acceptable, we used a mixed-method approach including self-report questionnaires and a focus group. To evaluate the impact of CCSH-TI, we assessed self-reported resilience, well-being, burnout, and team civility before and immediately after the intervention period (ClinicalTrials.gov identifier: NCT04060901 ). RESULTS: Attendance varied by team, but all teams had rates more than 60%. Coordinators rated high levels of credibility of CCSH-TI to improve burnout, and the majority reported that they received benefits, particularly in resilience and stress management, indicating acceptability. Coordinators randomly assigned to CCSH-TI reported an increase in resilience compared with coordinators randomly assigned to the wait-list group (F(41) = 4.53, P = .039). CONCLUSION: Data from this pilot study indicate that CCSH-TI may be a feasible, credible, acceptable, and effective intervention to augment individual resilience among CRCs. However, the quantitative and qualitative data suggest that more comprehensive and systematic programming is necessary to truly mitigate burnout.

Urgensi Ilmu Kedokteran Islam dengan Hukum Islam (Studi Identifikasi Deoxrybo Nucleic Acid (DNA) terhadap Sepersusuan)

2018 ◽  
Vol 12 (1) ◽  
pp. 133-146
Author(s):  
Li’izza Diana Manzil
Keyword(s):  
Nucleic Acid ◽  
Breast Milk ◽  
Legal Status ◽  
Islamic Law ◽  
Medical Science ◽  
Dna Identification ◽  
Islamic Medicine ◽  
Parents And Children ◽  
The Status ◽  
Brothers And Sisters

One sign of the rapidly growing world of medical science is its success in making one discovery about Deoxrybo Nucleid Acid (DNA). Islam does not prohibit the practice of DNA identification because it can be used in determining the legal status of relative relationships and related marital prohibitions among families because of the similarity of DNA genes between parents and their children. In Islam marriage prohibition can also occur between brothers and sisters. DNA identification can be done between siblings as a result of the presence of gene elements in breast milk. In addition, breast milk can also develop bone and grow meat if breastfeeding at least five times suction. But the results of DNA tests conducted between siblings cannot be more accurate if done to find relationships of parents and children. From this it clearly proves that Islamic medicine has an urgent value to Islamic law. This can be seen from one of its axiology in determining the status of brotherhood.

The Value of Neuroimaging Techniques in the Translation and Transdiagnostic Validation of Psychiatric Diagnoses - Selective Review

2020 ◽  
Vol 20 (7) ◽  
pp. 540-553 ◽  
Author(s):  
Anna Todeva-Radneva ◽  
Rositsa Paunova ◽  
Sevdalina Kandilarova ◽  
Drozdstoy St. Stoyanov
Keyword(s):  
Psychiatric Disorders ◽  
Psychiatric Symptoms ◽  
Medical Science ◽  
Self Report ◽  
Current Status ◽  
Diagnostic Tools ◽  
Main Concept ◽  
Directional Change ◽  
The Mind ◽  
Neuroimaging Techniques

: Psychiatric diagnosis has long been perceived as more of an art than a science since its foundations lie within the observation, and the self-report of the patients themselves and objective diagnostic biomarkers are lacking. Furthermore, the diagnostic tools in use not only stray away from the conventional medical framework but also remain invalidated with evidence-based concepts. However, neuroscience, as a source of valid objective knowledge has initiated the process of a paradigm shift underlined by the main concept of psychiatric disorders being “brain disorders”. It is also a bridge closing the explanatory gap among the different fields of medicine via the translation of the knowledge within a multidisciplinary framework. : The contemporary neuroimaging methods, such as fMRI provide researchers with an entirely new set of tools to reform the current status quo by creating an opportunity to define and validate objective biomarkers that can be translated into clinical practice. Combining multiple neuroimaging techniques with the knowledge of the role of genetic factors, neurochemical imbalance and neuroinflammatory processes in the etiopathophysiology of psychiatric disorders is a step towards a comprehensive biological explanation of psychiatric disorders and a final differentiation of psychiatry as a well-founded medical science. : In addition, the neuroscientific knowledge gained thus far suggests a necessity for directional change to exploring multidisciplinary concepts, such as multiple causality and dimensionality of psychiatric symptoms and disorders. A concomitant viewpoint transition of the notion of validity in psychiatry with a focus on an integrative validatory approach may facilitate the building of a collaborative bridge above the wall existing between the scientific fields analyzing the mind and those studying the brain.

scholarly journals Dental Applications of Carbon Nanotubes

Molecules ◽  
2021 ◽  
Vol 26 (15) ◽  
pp. 4423
Author(s):  
Marco A. Castro-Rojas ◽  
Yadira I. Vega-Cantu ◽  
Geoffrey A. Cordell ◽  
Aida Rodriguez-Garcia
Keyword(s):  
Mechanical Properties ◽  
Carbon Nanotubes ◽  
Oral Cavity ◽  
Current Status ◽  
Glass Ionomer ◽  
Oral Infections ◽  
Functional Behavior ◽  
The Status ◽  
Comprehensive Survey ◽  
Dental Applications

Glass ionomer cements and resin-based composites are promising materials in restorative dentistry. However, their limited mechanical properties and the risk of bulk/marginal fracture compromise their lifespan. Intensive research has been conducted to understand and develop new materials that can mimic the functional behavior of the oral cavity. Nanotechnological approaches have emerged to treat oral infections and become a part of scaffolds for tissue regeneration. Carbon nanotubes are promising materials to create multifunctional platforms for dental applications. This review provides a comprehensive survey of and information on the status of this state-of-the-art technology and describes the development of glass ionomers reinforced with carbon nanotubes possessing improved mechanical properties. The applications of carbon nanotubes in drug delivery and tissue engineering for healing infections and lesions of the oral cavity are also described. The review concludes with a summary of the current status and presents a vision of future applications of carbon nanotubes in the practice of dentistry.

Shared-Task Worklists Improve Clinical Trial Recruitment Workflow in an Academic Emergency Department

2021 ◽  
Vol 12 (02) ◽  
pp. 293-300
Author(s):  
Kevin S. Naceanceno ◽  
Stacey L. House ◽  
Phillip V. Asaro
Keyword(s):  
Clinical Trial ◽  
Emergency Department ◽  
Clinical Trials ◽  
Clinical Research ◽  
Substantial Reduction ◽  
Text Message ◽  
High Volume ◽  
Text Messages ◽  
Shared Task ◽  
Clinical Research Coordinators

Abstract Background Clinical trials performed in our emergency department at Barnes-Jewish Hospital utilize a centralized infrastructure for alerting, screening, and enrollment with rule-based alerts sent to clinical research coordinators. Previously, all alerts were delivered as text messages via dedicated cellular phones. As the number of ongoing clinical trials increased, the volume of alerts grew to an unmanageable level. Therefore, we have changed our primary notification delivery method to study-specific, shared-task worklists integrated with our pre-existing web-based screening documentation system. Objective To evaluate the effects on screening and recruitment workflow of replacing text-message delivery of clinical trial alerts with study-specific shared-task worklists in a high-volume academic emergency department supporting multiple concurrent clinical trials. Methods We analyzed retrospective data on alerting, screening, and enrollment for 10 active clinical trials pre- and postimplementation of shared-task worklists. Results Notifications signaling the presence of potentially eligible subjects for clinical trials were more likely to result in a screen (p < 0.001) with the implementation of shared-task worklists compared with notifications delivered as text messages for 8/10 clinical trials. The change in workflow did not alter the likelihood of a notification resulting in an enrollment (p = 0.473). The Director of Research reported a substantial reduction in the amount of time spent redirecting clinical research coordinator screening activities. Conclusion Shared-task worklists, with the functionalities we have described, offer a viable alternative to delivery of clinical trial alerts via text message directly to clinical research coordinators recruiting for multiple concurrent clinical trials in a high-volume academic emergency department.

Institutional repositories in Africa: Regaining direction

2021 ◽  
pp. 026666692110154
Author(s):  
Usman Ahmed Adam ◽  
Kiran Kaur
Keyword(s):  
Open Access ◽  
Research Output ◽  
Current Status ◽  
African Countries ◽  
Institutional Repositories ◽  
Widespread Implementation ◽  
Typical Performance ◽  
The Status ◽  
Global Access ◽  
And Cluster Analysis

Institutional repositories are powerful tools to facilitate global access to intellectual output by members of the institution, particularly in assisting them to preserve and maximize access to their research output globally. This exploratory study of the status of institutional repositories implementation in African countries using the global Directory of Open Access Repositories (OpenDOAR) and Transparent Ranking: All Repositories by Google Scholar, reports on the operational status and the performance of repositories. Factor analysis and cluster analysis are used to analyze the operational level of institutional repositories in African countries. The analysis showed that the typical performance of institutional repositories remains below average. The possibility of global open access to research results through institutional repositories in South Africa, Kenya, Nigeria, Algeria, Sudan, and Egypt appeared to be relatively more feasible than other African countries. This study concludes that many organizations, institutions, and societies spend great efforts in support of open access implementation in Africa, however, the widespread implementation of institutional repositories is still very slow paced, and the performance of the implemented repositories was below expectation. Suggestions for regaining the intended direction of African institutional repositories are given based on the current status.

scholarly journals Research Trends of Acupuncture Therapy on Cancer Over the Past Two Decades: A Bibliometric Analysis

2020 ◽  
Vol 19 ◽  
pp. 153473542095944
Author(s):  
Jing Guo ◽  
Lixia Pei ◽  
Lu Chen ◽  
Hao Chen ◽  
Dongmei Gu ◽  
...  
Keyword(s):  
Neuropathic Pain ◽  
Acupuncture Therapy ◽  
Supportive Care ◽  
Bibliometric Analysis ◽  
Integrative Medicine ◽  
Clinical Studies ◽  
Current Status ◽  
Cancer Center ◽  
Future Research ◽  
The Past

Purpose: Acupuncture has been used for managing cancer-related symptoms. However, there are still few studies concerning the overall trends in acupuncture therapy on cancer based on bibliometric analysis. This study aims to demonstrate the current status and trends in this field over the past 2 decades. Methods: Articles were retrieved from the Web of Science from 2000 to 2019. CiteSpace was used for co-authorship network of countries/institutions, dual-map analysis, and detecting the keywords with citation bursts. VOSviewer was used to construct networks based on co-authorship and co-citation analysis of authors, and co-occurrence of keywords. Results: A total of 927 articles and reviews were included in the final analysis. The number of publications has steadily increased with some fluctuations among years. The country and institution contributing most to this field are the USA and Memorial Sloan Kettering Cancer Center. Mao JJ was the most productive author and Molassiotis A ranked first in the cited authors. The co-occurrence analysis revealed 5 clusters (including “clinical trials,” “clinical studies on chemotherapy/radiation-induced symptoms,” “CAM therapy for cancer,” “clinical studies on vasomotor symptoms,” and “systematic reviews”). Most recent keyword bursts were “neuropathic pain,” “arthralgia,” “prevention,” “supportive care,” and “integrative medicine”. Conclusions: The annual publication output would increase rapidly in the next decade, which shows a promising future in this research field. Future research hotspots would focus on the role of acupuncture in neuropathic pain, arthralgia, prevention, supportive care, and integrative medicine.

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