scholarly journals LITERATURE REVIEW: KANDUNGAN BAWANG HITAM SEBAGAI REKOMENDASI PENCEGAHAN INFEKSI IBU POSTPARTUM

2021 ◽  
Vol 5 (2) ◽  
pp. 9
Author(s):  
Indah Nurhasanah ◽  
Febi Ratnasari ◽  
Lastri Mei Winarni

Infeksi postpartum dapat menyebabkan kematian pada ibu. Sehing ga harus dilakukan pencegahan. Salah satunya dengan mengkonsumsi makanan yang bernutrisi sehingga dapat mencegah infeksi postpartum. Tujuan penelitian ini untuk melakukan review artikel yang membahas kandungan bawang hitam untuk pencegahan infeksi ibu  postpartum. Metode pada penelitian ini yaitu Jenis review  yang digunakan adalah traditional review dan  study literature ini menggunakan jurnal atau literature pada terbitan tahun 2016-2020 yang ditampilkan secara full text. Hasil penelitian menunjukan bahwa bawang hitam memiliki antioksidan yang tinggi dan juga kandungan nutrisi yang lengkap, seperti karbohidrat, zat besi, asam amino, protein, vitamin K, mengandung gula (glukosa, fruktosa, sukrosa, dan maltosa) pada bawang hitam lebih tinggi dibandingkan bawang putih yang segar. Selain itu bawang hitam memiliki kandungan senyawa organosulfur yaitu S-allycysteine sehingga dapat mencegah timbulnya bakteri penyebab infeksi. Sehingga disarankan untuk melakukan penelitian lebih lanjut mengenai kebersihan proses fermentasi pada bawang putih segar. 

Author(s):  
Ida Stadig ◽  
Therese Svanberg

Abstract Objectives This article aims to provide a brief review of information retrieval and hospital-based health technology assessment (HB-HTA) and describe library experiences and working methods at a regional HB-HTA center from the center's inception to the present day. Methods For this brief literature review, searches in PubMed and LISTA were conducted to identify studies reporting on HB-HTA and information retrieval. The description of the library's involvement in the HTA center and its working methods is based on the authors’ experience and internal and/or unpublished documents. Results Region Västra Götaland is the second largest healthcare region in Sweden and has had a regional HB-HTA center since 2007 (HTA-centrum). Assessments are performed by clinicians supported by HTA methodologists. The medical library at Sahlgrenska University Hospital works closely with HTA-centrum, with one HTA librarian responsible for coordinating the work. Conclusion In the literature on HB-HTA, we found limited descriptions of the role librarians and information specialists play in different units. The librarians at HTA-centrum play an important role, not only in literature searching but also in abstract and full-text screening.


2021 ◽  
Vol 3 (1) ◽  
pp. 179-188
Author(s):  
Fryda Liana Devi

Diketahui jutaan orang di seluruh dunia telah mengalami nyeri neuropatik yang diperkirakan terjadi pada sebanyak 7% dari populasi. Nyeri neuropatik merupakan salah satu jenis nyeri yang timbul akibat adanya lesi atau gangguan primer pada susunan saraf. Nyeri ini dapat terjadi akibat berbagai gangguan, seperti penyakit infeksi, trauma, radikulopati dan kerusakan di sistem endokrin. Tujuan dari literature review iniadalah untuk meninjau lebih lanjut terkait masalah nyeri neuropatik yang umum terjadi sehingga dapat diketahui langkah manajemen masalah ini dengan tepatdi masyarakat.Metode. Penelitian ini merupakan studi literature review yang melibatkan sebanyak 21 sumber pustaka. Kata kunci yang digunakan dalam penelusuran yaitu ‘neuropathic pain dan management dengan tahun terbit antara  2009-2020. Abstrak dan full text jurnal dibaca dan dicermati, kemudian dilakukan analisis terhadap isi yang terdapat dalam tujuan penelitian dan hasil/temuan penelitian. Hasil. Berbagai penelitian menunjukkan farmakoterapi sering kali merupakan salah satu langkah yang efektif yang dapat dengan cepat memberikan dasar untuk implementasi komponen lain dari manajemen nyeri, seperti modalitas terapi fisik dan keterampilan koping pasien.Pendekatan multidisiplin dan multimodal dalam manajemen nyeri neuropati dapat meredakan derajat nyeri untuk sebagian besar pasien yang menderita nyeri neuropati. Beberapa jenis obat yang direkomendasikan dalam pengobatan nyeri neuropatik, antara lain golongan obat anti-depresan, antikonvulsan, obat topikal dan golongan analgetik.


2017 ◽  
Vol 63 (10) ◽  
pp. 633-639
Author(s):  
Simona Dvořáčková ◽  
Kateřina Ládová ◽  
Josef Malý ◽  
Jozef Kolář ◽  
Miroslav Penka

2020 ◽  
Vol 3 (1) ◽  
pp. 21-30
Author(s):  
Cantika Larasati

Diabetes melitus merupakan kelainan metabolisme kronis yang ditandai dengan hiperglikemia dengan gangguan metabolisme karbohidrat, lemak, dan protein. Pasien dengan diabetes mellitus seringkali memiliki kontrol glikemik yang buruk dan memiliki banyak risiko komplikasi mikrovaskuler. Obat hipoglikemik sintetik tidak dapat sepenuhnya mengontrol kadar glukosa serta seringkali menimbulkan efek samping yang menyebabkan ketidakpatuhan pasien minum obat. Selama berabad-abad, obat-obatan herbal telah banyak digunakan untuk mengobati berbagai macam penyakit yang sampai saat ini masih digunakan sebagai alternatif pertama untuk menyembuhkan penyakit tertentu di negara berkembang. Aloe vera telah digunakan oleh berbagai budaya karena khasiat obatnya yang luar biasa. Penelitian ini merupakan  literature review yang melibatkan sebanyak 21 sumber pustaka dengan kata kunci yang digunakan yaitu ‘aloe vera dan diabetes’ dengan tahun terbit antara 2009- 2020. Abstrak dan full text jurnal dibaca dan dicermati, kemudian dilakukan analisis terhadap isi yang terdapat dalam tujuan penelitian dan hasil/temuan penelitian. Banyak studi menunjukkan ekstrak aloe vera dapat berperan dalam menurunkan glukosa darah pada penderita diabetes mellitus dan komplikasinya melalui berbagai mekanisme, seperti menurunkan glukoneogenesis dan lipogenesis, serta meningkatkan glikolisis di hati. Selain itu, aloe vera dapat mempengaruhi ekspresi gen berbeda yang terkait dengan metabolisme glukosa dan lipid. serta dikaitkan dengan aktivasi transkripsi PPAR. Kandungan senyawa dan vitamin didalamnya juga berperan sebagai antioksidan. Kandungan senyawa pada gel aloe vera menunjukkan berbagai manfaat antidiabetes, dan kandungan polisakarida di dalamnya dianggap sebagai komponen aktif utama untuk manfaat tersebut.


2021 ◽  
Author(s):  
Thabo Michael Yates ◽  
Antoine Lain ◽  
Jamie Campbell ◽  
T. Ian Simpson ◽  
David R FitzPatrick

There are >2500 different genetically-determined developmental disorders (DD), which, as a group, show very high levels of both locus and allelic heterogeneity. This has led to the wide-spread use of evidence-based filtering of genome-wide sequence data as a diagnostic tool in DD. Determining whether the association of a filtered variant at a specific locus is a plausible explanation of the phenotype in the proband is crucial and commonly requires extensive manual literature review by both clinical scientists and clinicians. Access to a database of weighted clinical features extracted from rigorously curated literature would increase the efficiency of this process and facilitate the development of robust phenotypic similarity metrics. However, given the large and rapidly increasing volume of published information, conventional biocuration approaches are becoming impractical. Here, we present a scalable, automated method for extraction of categorical phenotypic descriptors from full-text literature. Papers identified through literature review were downloaded and parsed using the Cadmus custom retrieval package. Human Phenotype Ontology terms were extracted using MetaMap, with 76-83% precision and 72-81% recall. Mean terms per paper increased from 9 in title + abstract, to 69 using full text. We demonstrate that these literature-derived disease models plausibly reflect true disease expressivity more accurately than gold standard manually-curated models, through comparison with prospectively gathered data from the Deciphering Developmental Disorders study. AUC for ROC curves increased by 5-10% through use of literature-derived models. This work shows that scalable automated literature curation increases performance and adds weight to the need for this strategy to be integrated into informatic variant analysis pipelines.


2021 ◽  
Vol 1 ◽  
pp. 1103-1110
Author(s):  
Didi Rethodi ◽  
Dian Kartikasari

AbstractAsthma causes narrowing of the airways, which leads to various symptoms such as whezzing, coughing, and shortness of breath (dyspnea) in sufferers. Patients with asthma often complain of experiencing sudden shortness of breath, difficulty breathing, and pain when taking a breath. These conditions can causes the patient to become stressed, anxious and the breathing pattern in no longer effective. As a result, the prognosis of disease is poor. The purpose of this literature review study was to picture the frequency of breathing in asthma patients.This literature review highlighted five articles searched from 2011-2021 throught Garba Garuda and Google Scholar. The obtained articles were apprassied using the JBI (Joanna Briggs Institute) instrument before being analyzed. This study revealed that the respiratory rate in patients with asthma increases over 20x/minutes.The conclusion from this literature review is that patients with asthma have tachypnea. This literature review may be used as a reference for hospitals, educational institutions, and other researchers to determine appropriate nursing interventions for asthma patients.Keywords:Asthma; respiratoryrate. AbstrakPenyakit asma dapat menyebabkan penyempitan pada saluran napas dan hal ini dapat menimbulkan gejala seperti mengi, batuk, dan sesak napas (dyspnea) pada penderitanya. Keluhan pasien asma yaitu sering mengalami sesak napas yang dating secara mendadak, sulit untuk bernafas, nyeri saat menarik napas. Hal ini dapat menyebabkan pasien menjadi stress, cemas dan pola napas tidak lagi efektif dan prognosis penyakitnya menjadi buruk. Tujuan dari penelitian literature review ini adalah untuk mengetahui Gambaran Frekuensi Napas Pada Pasien Asma. Metode penelitian menggunakan metode deskriptif dengan pengumpulan data literature review. Pencarian artikel dari tahun 2011-2021 melalui penelusuran Garba Garuda, dan Google Shcolar dengan kriteria inklusi populasi pasien asma dewasa, tahun artikel 2011-2021, penelitian kuantitatif. Hasil pencarian yang didapatkan berupa full text dan pdf, kemudian direview dengan menggunakan instrument JBI (Joanna Briggs Institute), didapatkan 5 artikel dari tahun 2012-2021, diekstraksi kemudian dibahas dan disimpulkan .Hasil penelitian literature review dari 5 atikel menunjukkan bahwa frekuensi napas pada pasien dengan kejadian asma mengalami peningkatan pernafasan >20x/menit. Simpulan dari literature review ini yaitu pasien dengan kejadian asma mengalami peningkatan frekuensi pernapasan. Penelitian literature review ini diharapkan dapat menjadi refrensi bagi pihak rumah sakit, institusi pendidikan maupun penelitilainnya sebagai pertimbangan untuk menentukan intervensi keperawatan yang tepat bagi pasien asma.Kata kunci : Asma, Respirasi


Author(s):  
Tomasz A. Dziedzic ◽  
Artur Balasa ◽  
Mateusz P. Jeżewski ◽  
Łukasz Michałowski ◽  
Andrzej Marchel

Abstract The aim of this literature review is to present a summary of the published literature relating the details of the different modifications of specimen preparation for white matter dissection with the Klingler technique. For this review, 3 independent investigators performed an electronic literature search that was carried out in the Pubmed, Scopus and Web of Science databses up to December 2019. Furthermore, we performed citation tracking for the articles missed in the initial search. Studies were eligible for inclusion when they reported details of at least the first 2 main steps of Klingler’s technique: fixation and freezing. A total of 37 full-text articles were included in the analysis. We included original anatomical studies in which human white matter dissection was performed for study purposes. The main three steps of preparation are the same in each laboratory, but the details of each vary between studies. Ten percent formalin is the most commonly used (34 studies) solution for fixation. The freezing time varied between 8 h and a month, and the temperature varied from − 5 to − 80 °C. After thawing and during dissections, the specimens were most often kept in formalin solution (13), and the concentration varied from 4 to 10%. Klingler’s preparation technique involves three main steps: fixation, freezing and thawing. Even though the details of the technique are different in most of the studies, all provide subjectively good quality specimens for anatomical dissections and studies.


2006 ◽  
Vol 22 (2) ◽  
pp. 235-241 ◽  
Author(s):  
Pirjo Räsänen ◽  
Eija Roine ◽  
Harri Sintonen ◽  
Virpi Semberg-Konttinen ◽  
Olli-Pekka Ryynänen ◽  
...  

Objectives: The objectives of this study were to identify, in a systematic literature review, published studies having used quality-adjusted life years (QALYs) based on actual measurements of patients' health-related quality of life (HRQoL) and to determine which HRQoL instruments have been used to calculate QALYs. Furthermore, the aims were to characterize studies with regard to medical specialty, intervention studied, results obtained, quality, country of origin, QALY gain observed, and interpretation of results regarding cost-effectiveness.Methods: Systematic searches of the literature were made using the MEDLINE, Embase, CINAHL, SCI, and Cochrane Library electronic databases. Initial screening of identified articles was based on abstracts read independently by two of the authors; full-text articles were again evaluated by two authors, who made the final decision on which articles should be included.Results: The search identified 3,882 articles; 624 were obtained for closer review. Of the reviewed full-text articles, seventy reported QALYs based on actual before–after measurements using a valid HRQoL instrument. The most frequently used instrument was EuroQol HRQoL instrument (EQ-5D, 47.5 percent). Other instruments used were Health Utilities Index (HUI, 8.8 percent), the Rosser–Kind Index (6.3 percent), Quality of Well-Being (QWB, 6.3 percent), Short Form-6D (SF-6D, 5.0 percent), and 15D (2.5 percent). The rest (23.8 percent) used a direct valuation method: Time Trade-Off (10.0 percent), Standard Gamble (5.0 percent), visual analogue scale (5.0 percent), or rating scale (3.8 percent). The most frequently studied medical specialties were orthopedics (15.5 percent), pulmonary diseases (12.7 percent), and cardiology (9.9 percent). Ninety percent of the studies came from four countries: United Kingdom, United States, Canada, the Netherlands. Approximately half of the papers were methodologically high quality randomized trials. Forty-nine percent of the studied interventions were viewed by the authors of the original studies as being cost-effective; only 13 percent of interventions were deemed not to be cost-effective.Conclusions: Although QALYs gained are considered an important measure of effectiveness of health care, the number of studies in which QALYs are based on actual measurements of patients' HRQoL is still fairly limited.


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