Comparison of the prevalence of metabolic syndrome in patients with schizophrenia and bipolar disorder: a cross-sectional study from Black Sea region

Objective: This study aimed to compare the prevalence of metabolic syndrome and hyperhomocysteinemia and to specify predictors of the metabolic syndrome among patients with schizophrenia and bipolar disorder. Method: This cross sectional study was conducted on 100 patients with schizophrenia and 100 patients with bipolar disorder. The participants' metabolic syndrome was determined according to the criteria set by Third Report of the National Cholesterol Education Program–Adult Treatment Panel III. Hyperhomocysteinemia was considered as homocysteine levels higher than 15 µmol/L. Chi-square test, Fisher's exact test, student t test, Mann-Whitney test, and logistic regression were used for data analysis. Results: The prevalence of metabolic syndrome was not significantly different (P = 0.07) between patients with schizophrenia (27%) and bipolar disorder (39%). No statistically significant difference (P = 0.17) was observed between patients with schizophrenia (82%) and bipolar disorder (74%) in the prevalence of hyperhomocysteinemia. The results of multivariable logistic regression model showed a significant association of smoking and BMI with metabolic syndrome in patients with schizophrenia (OR = 3.69, 95% CI: 1.13-12.05, and OR = 1.38, 95% CI: 1.20-1.60, respectively). In patients with bipolar disorder, BMI was a significant predictor of developing metabolic syndrome (OR = 1.29, 95% CI: 1.14-1.47). Metabolic syndrome was more prevalent in women than in men in both diagnostic groups (P < 0.05). No significant difference was observed in hyperhomocysteinemia prevalence between male and female patients with schizophrenia (P = 1.00). However, hyperhomocysteinemia was more prevalent in males than in females among patients with bipolar disorder (P = 0.001). Conclusion: Findings showed a high prevalence of metabolic syndrome and hyperhomocysteinemia among patients with schizophrenia and bipolar disorder. To deal with this problem, regular monitoring and conducting early interventions are recommended to determine the metabolic risk profile and to prevent the cardiovascular diseases.

Download Full-text

Factors associated with current smoking in COPD patients: A cross-sectional study from the Eastern Black Sea region of Turkey

Tobacco Induced Diseases ◽

10.18332/tid/90665 ◽

2018 ◽

Vol 16 (May) ◽

Cited By ~ 1

Author(s):

Dilek Karadogan ◽

Ozgur Onal ◽

Deniz Sahin ◽

Yalcın Kanbay

Keyword(s):

Black Sea ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Current Smoking ◽

Black Sea Region ◽

Factors Associated ◽

Copd Patients

Download Full-text

Association between metabolic syndrome and thyroid stimulating hormone - A cross sectional study

Medpusle International Journal of Medicine ◽

10.26611/1021922 ◽

2019 ◽

Vol 9 (2) ◽

pp. 87-90

Author(s):

Karanam Madhuri ◽

◽

Rishi Kumar Venkatachalam ◽

A Nasreen Begum ◽

Shamsheer Khan P ◽

...

Keyword(s):

Metabolic Syndrome ◽

Cross Sectional Study ◽

Thyroid Stimulating Hormone ◽

Sectional Study ◽

Cross Sectional ◽

Stimulating Hormone

Download Full-text

Impact of high visceral adiposity index associated with metabolic syndrome on erectile function in sexually active men: results of a cross‐sectional study

International Journal of Clinical Practice ◽

10.1111/ijcp.14111 ◽

2021 ◽

Author(s):

Mustafa Suat Bolat ◽

Mustafa Latif Ozbek ◽

Bekir Şahin ◽

Merve Yılmaz ◽

Fatih Kocamanoglu ◽

...

Keyword(s):

Metabolic Syndrome ◽

Erectile Function ◽

Cross Sectional Study ◽

Visceral Adiposity ◽

Visceral Adiposity Index ◽

Sexually Active ◽

Sectional Study ◽

Cross Sectional ◽

Adiposity Index

Download Full-text

The association between dietary antioxidant quality score with metabolic syndrome and its components in Iranian adults: A cross‐sectional study

Food Science & Nutrition ◽

10.1002/fsn3.2067 ◽

2020 ◽

Author(s):

Mahshid Shahavandi ◽

Hossein Shahinfar ◽

Nastaran payande ◽

Fatemeh Sheikhhossein ◽

Kurosh Djafarian ◽

...

Keyword(s):

Metabolic Syndrome ◽

Cross Sectional Study ◽

Quality Score ◽

Sectional Study ◽

Cross Sectional ◽

Dietary Antioxidant

Download Full-text

Magnitude of internalised stigma and associated factors among people with bipolar disorder at Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia: a cross-sectional study

BMJ Open ◽

10.1136/bmjopen-2020-044824 ◽

2021 ◽

Vol 11 (4) ◽

pp. e044824

Author(s):

Shegaye Shumet ◽

Bethlehem W/Michele ◽

Dessie Angaw ◽

Temesgen Ergete ◽

Nigus Alemnew

Keyword(s):

Social Support ◽

Bipolar Disorder ◽

Associated Factors ◽

Addis Ababa ◽

Self Esteem ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Specialized Hospital ◽

Poor Social Support

ObjectivesTo assess the magnitude of internalised stigma and associated factors among patients with bipolar disorder attending the outpatient department of Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia.DesignInstitution-based cross-sectional study design.SettingAmanuel Mental Specialized Hospital, Addis Ababa, Ethiopia.ParticipantsWe recruited about 418 participants using systematic sampling technique for an interview during the study period.MeasurementData were collected by face-to-face interviews. Internalized Stigma of Mental Illness scale was used to measure internalised stigma. The Rosenberg Self-Esteem Scale and the Oslo-3 Social Support were instruments used to assess the associated factors. Bivariate and multivariate logistic regressions were performed to identify factors associated with the outcome variable. ORs with 95% CI were computed to determine the level of significance.ResultsThe magnitude of internalised stigma was 24.9% (95% CI: 21.2% to 28.9%). In the multivariate analysis, unemployed (adjusted OR (AOR)=2.3, 95% CI: 1.0 to 5.0), unable to read and write (AOR=3.3, 95% CI: 1.05 to 10.7), poor social support (AOR=5.3, 95% CI: 1.9 to 15.0), ≥4 previous hospitalisations due to bipolar disorder (AOR=2.6, 95% CI: 1.1 to 6.1) and low self-esteem (AOR=2.4, 95% CI: 1.1 to 5.1) had a significant association with internalised stigma.ConclusionsOne in four patients with bipolar disorder reported high internalised stigma. Unemployment, low educational status, low self-esteem, poor social support and being hospitalised more than three times before were significantly associated with internalised stigma. Thus, a stigma-reduction programme focusing on self-esteem improvement and psychological health of patients to increase their stigma resistance to counteracting effects of internalised stigma is essential.

Download Full-text

Association of Serum Bilirubin Level with Metabolic Syndrome and Non-Alcoholic Fatty Liver Disease: A Cross-Sectional Study of 1672 Obese Children

Journal of Clinical Medicine ◽

10.3390/jcm10132812 ◽

2021 ◽

Vol 10 (13) ◽

pp. 2812

Author(s):

Cristina Bellarosa ◽

Giorgio Bedogni ◽

Annalisa Bianco ◽

Sabrina Cicolini ◽

Diana Caroli ◽

...

Keyword(s):

Metabolic Syndrome ◽

Fatty Liver ◽

Fatty Liver Disease ◽

Serum Bilirubin ◽

Cross Sectional Study ◽

Sectional Study ◽

Obese Children ◽

Cross Sectional ◽

Alcoholic Fatty Liver ◽

Alcoholic Fatty Liver Disease

As in adults, obesity also plays a central role in the development of metabolic syndrome (MS) in children. Non-alcoholic fatty liver disease (NAFLD) is considered a manifestation of MS. Not only MS but also NAFLD seem to be inversely associated with serum bilirubin concentrations, an important endogenous tissue protector when only mild elevated. The aim of the study was to evaluate the association between serum bilirubin levels and the prevalence of MS and NAFLD in Italian obese children and adolescents. A retrospective cross-sectional study was performed in 1672 patients aged from 5 to 18 years. Clinical and laboratory parameters were assessed. NAFLD was measured by liver ultrasonography. The study was approved by the Ethical Committee of the Istituto Auxologico Italiano (research project code 1C021_2020, acronym BILOB). MS was present in 24% and fatty liver (FL) in 38% of this population. Bilirubin was not associated with FL and MS as a whole, but it was inversely associated only with selected components of MS, i.e., large WC, high blood pressure and high triglycerides. Our data suggest that bilirubin is not protective against MS and NAFLD in the presence of severe obesity.

Download Full-text