scholarly journals Real-life risk factors of inadequate procedure prior to colonoscopy in a Turkish population

2022 ◽  
Vol 11 (1) ◽  
pp. 36
Author(s):  
Abdullah Yeniova ◽  
Giray Akgul ◽  
Edinc Yenidogan ◽  
Suleyman Gunay
Keyword(s):  
Risk Factors ◽  
Real Life ◽  
Turkish Population

scholarly journals Cumulative Risks from Stressor Exposures and Personal Risk Factors in the Workplace: Examples from a Scoping Review

2021 ◽  
Vol 18 (11) ◽  
pp. 5850
Author(s):  
Mary A. Fox ◽  
Richard Todd Niemeier ◽  
Naomi Hudson ◽  
Miriam R. Siegel ◽  
Gary Scott Dotson
Keyword(s):  
Risk Factors ◽  
Risk Assessment ◽  
Scoping Review ◽  
Multiple Stressors ◽  
Cumulative Risk ◽  
Real Life ◽  
Personal Factors ◽  
Exposure Limits ◽  
Personal Risk ◽  
Personal Risk Factors

Protecting worker and public health involves an understanding of multiple determinants, including exposures to biological, chemical, or physical agents or stressors in combination with other determinants including type of employment, health status, and individual behaviors. This has been illustrated during the COVID-19 pandemic by increased exposure and health risks for essential workers and those with pre-existing conditions, and mask-wearing behavior. Health risk assessment practices for environmental and occupational health typically do not incorporate multiple stressors in combination with personal risk factors. While conceptual developments in cumulative risk assessment to inform a more holistic approach to these real-life conditions have progressed, gaps remain, and practical methods and applications are rare. This scoping review characterizes existing evidence of combined stressor exposures and personal factors and risk to foster methods for occupational cumulative risk assessment. The review found examples from many workplaces, such as manufacturing, offices, and health care; exposures to chemical, physical, and psychosocial stressors combined with modifiable and unmodifiable determinants of health; and outcomes including respiratory function and disease, cancers, cardio-metabolic diseases, and hearing loss, as well as increased fertility, menstrual dysfunction and worsened mental health. To protect workers, workplace exposures and modifiable and unmodifiable characteristics should be considered in risk assessment and management. Data on combination exposures can improve assessments and risk estimates and inform protective exposure limits and management strategies.

Incidence and risk factors for dupilumab associated ocular adverse events: a real‐life prospective study

2020 ◽  
Author(s):  
A.T. Touhouche ◽  
M. Cassagne ◽  
E. Bérard ◽  
F. Giordano‐Labadie ◽  
A. Didier ◽  
...  
Keyword(s):  
Risk Factors ◽  
Adverse Events ◽  
Prospective Study ◽  
Real Life

scholarly journals Adverse drug reactions associated with treatment in patients with chronic rheumatic diseases in childhood: a retrospective real life review of a single center cohort

2020 ◽  
Vol 60 (1) ◽  
Author(s):  
Manar Amanouil Said ◽  
Liana Soido Teixeira e Silva ◽  
Aline Maria de Oliveira Rocha ◽  
Gustavo Guimarães Barreto Alves ◽  
Daniela Gerent Petry Piotto ◽  
...  
Keyword(s):  
Risk Factors ◽  
Regression Model ◽  
Children And Adolescents ◽  
Adverse Drug Reactions ◽  
Rheumatic Diseases ◽  
Real Life ◽  
Drug Reactions ◽  
Wide Range ◽  
Disease Modifying ◽  
Chronic Rheumatic Diseases

Abstract Background Adverse drug reactions (ADRs) are the sixth leading causes of death worldwide; monitoring them is fundamental, especially in patients with disorders like chronic rheumatic diseases (CRDs). The study aimed to describe the ADRs investigating their severity and associated factors and resulting interventions in pediatric patients with CRDs. Methods A retrospective, descriptive and analytical study was conducted on a cohort of children and adolescents with juvenile idiopathic arthritis (JIA), juvenile systemic lupus erythematosus (JSLE) and juvenile dermatomyositis (JDM). The study evaluated medical records of the patients to determine the causality and the management of ADRs. In order to investigate the risk factors that would increase the risk of ADRs, a logistic regression model was carried out on a group of patients treated with the main used drug. Results We observed 949 ADRs in 547 patients studied. Methotrexate (MTX) was the most frequently used medication and also the cause of the most ADRs, which occurred in 63.3% of patients, followed by glucocorticoids (GCs). Comparing synthetic disease-modifying anti-rheumatic drugs (sDMARDs) vs biologic disease-modifying anti-rheumatic drugs (bDMARDs), the ADRs attributed to the former were by far higher than the latter. In general, the severity of ADRs was moderate and manageable. Drug withdrawal occurred in almost a quarter of the cases. In terms of risk factors, most patients who experienced ADRs due to MTX, were 16 years old or younger and received MTX in doses equal or higher than 0.6 mg/kg/week. Patients with JIA and JDM had a lower risk of ADRs than patients with JSLE. In the multiple regression model, the use of GCs for over 6 months led to an increase of 0.5% in the number of ADRs. Conclusions Although the ADRs highly likely affect a wide range of children and adolescents with CRDs they were considered moderate and manageable cases mostly. However, triggers of ADRs need further investigations.

scholarly journals Longitudinal Asthma Patterns in Italian Adult General Population Samples: Host and Environmental Risk Factors

2020 ◽  
Vol 9 (11) ◽  
pp. 3632
Author(s):  
Sara Maio ◽  
Sandra Baldacci ◽  
Marzia Simoni ◽  
Anna Angino ◽  
Stefania La Grutta ◽  
...  
Keyword(s):  
Risk Factors ◽  
General Population ◽  
Multinomial Logistic Regression ◽  
Population Sample ◽  
Real Life ◽  
Persistent Asthma ◽  
Asthma Diagnosis ◽  
Longitudinal Patterns ◽  
Asthma Symptoms ◽  
Passive Smoke

Background: Asthma patterns are not well established in epidemiological studies. Aim: To assess asthma patterns and risk factors in an adult general population sample. Methods: In total, 452 individuals reporting asthma symptoms/diagnosis in previous surveys participated in the AGAVE survey (2011–2014). Latent transition analysis (LTA) was performed to detect baseline and 12-month follow-up asthma phenotypes and longitudinal patterns. Risk factors associated with longitudinal patterns were assessed through multinomial logistic regression. Results: LTA detected four longitudinal patterns: persistent asthma diagnosis with symptoms, 27.2%; persistent asthma diagnosis without symptoms, 4.6%; persistent asthma symptoms without diagnosis, 44.0%; and ex -asthma, 24.1%. The longitudinal patterns were differently associated with asthma comorbidities. Persistent asthma diagnosis with symptoms showed associations with passive smoke (OR 2.64, 95% CI 1.10–6.33) and traffic exposure (OR 1.86, 95% CI 1.02–3.38), while persistent asthma symptoms (without diagnosis) with passive smoke (OR 3.28, 95% CI 1.41–7.66) and active smoke (OR 6.24, 95% CI 2.68–14.51). Conclusions: LTA identified three cross-sectional phenotypes and their four longitudinal patterns in a real-life setting. The results highlight the necessity of a careful monitoring of exposure to active/passive smoke and vehicular traffic, possible determinants of occurrence of asthma symptoms (with or without diagnosis). Such information could help affected patients and physicians in prevention and management strategies.

scholarly journals Prevalence and impact of risk factors for poor asthma outcomes in a large, specialist-managed patient cohort: a real-life study

2019 ◽  
Vol Volume 12 ◽  
pp. 297-307 ◽  
Author(s):  
Gábor Tomisa ◽  
Alpár Horváth ◽  
Zsuzsanna Szalai ◽  
Veronika Müller ◽  
Lilla Tamási
Keyword(s):  
Risk Factors ◽  
Real Life ◽  
Life Study ◽  
Patient Cohort ◽  
Asthma Outcomes ◽  
Real Life Study

Safety of uSCIT-MPL-4: prevalence and risk factors of systemic reactions in real life

Immunotherapy ◽  
2019 ◽  
Vol 11 (9) ◽  
pp. 783-794
Author(s):  
Marco Caminati ◽  
Alessandra Arcolaci ◽  
Massimo Guerriero ◽  
Giuseppina Manzotti ◽  
Mariangiola Crivellaro ◽  
...  
Keyword(s):  
Risk Factors ◽  
Real Life ◽  
Systemic Reactions

scholarly journals Prevalence of HPV Genotypes in South Europe: Comparisons between an Italian and a Turkish Unvaccinated Population

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Maria Teresa Schettino ◽  
Pasquale De Franciscis ◽  
Antonio Schiattarella ◽  
Viviana La Manna ◽  
Alessandra Della Gala ◽  
...  
Keyword(s):  
Risk Factors ◽  
Population Group ◽  
Turkish Population ◽  
Hpv Infection ◽  
Italian Population ◽  
Turkish Women ◽  
Sexually Transmitted ◽  
Italian Women ◽  
Cytological Alterations ◽  
Associated Risk Factors

The human papilloma virus (HPV) is a DNA virus associated with benign and malignant lesions of skin and mucous membranes and is the most common sexually transmitted viral infection worldwide. We investigated the prevalence of HPV infection and associated risk factors in Italian and Turkish women population attending the gynecology outpatients clinic in Naples (Italy) and Pamukkale (Turkey). Women were enrolled from the Department of Obstetrics and Gynecology of the University of Campania “Luigi Vanvitelli” in Naples (Italy) and of “Pamukkale University” in Denizli (Turkey) between January 2014 and June 2015. A questionnaire that included sociodemographic and sexual behavior characteristics, questions about HPV awareness, vaccine status, and reasons for not wanting to get vaccinated, and HPV-related knowledge was completed for each participant, and cervical cytology samples were collected. The prevalence of HPV infection was higher in the Italian group (52.6% vs 32.6%, p<0.001), while the distribution of genotypes is similar (p=0.325). Moreover, the differences in cytological alterations in these patients are significant (p<0.001). The analysis showed a higher prevalence of sexual behavioral characteristics (p<0.001) and better attention to the execution of the screening test in the Italian population (p<0.001). Italian women showed more knowledge and propensity to vaccination compared to Turkish women (p<0.001). Our data highlighted three relevant aspects: the different prevalence of cytological abnormalities, the different distribution of risk factors and, above all, the different attitude of women towards the primary prevention of cervical cancer between an Italian and a Turkish population group.

scholarly journals P1822 Exercise stress echo in the preventive assessment of the coronary heart disease: experience in the real life practice

2020 ◽  
Vol 21 (Supplement_1) ◽  
Author(s):  
F Acquistapace
Keyword(s):  
Risk Factors ◽  
Cost Effectiveness ◽  
Real Life ◽  
Exercise Stress ◽  
Primary Role ◽  
Cost Effectiveness Ratio ◽  
Multiple Risk Factors ◽  
Stress Echo ◽  
Artery Disease ◽  
Primary Evaluation

Abstract The predictive of the functional tests compared to the anatomical tests in the diagnosis of coronary artery disease (CAD) is still debated. Cost-effectiveness ratio play a primary role in the best application of clinical practice.Methods 3200 pts (1600 men and 1600 women) were selected during a medical and cardiological screening. Two groups. The first one: evaluation or absence of events and the second one: presence of CAD. Evaluated datas: risk factors (FRC) and presence of clinical parameters limiting the predictive value of the Stress ECG from Effort (EE) such as: ECG’s abnormalities, branch blocks, hypertrophic, cardiomyopathy, gender. FRC evaluated parameters: hypertension 2080 (65.5%: 1040m; 1040f), hypercholesterolemia 1084 (37%: 592m; 592f), smoking 595 (18.6%: 298m; 297f), familiarity 1088 (34%: 1038m; 1042f), anxiety, depression, dystonia 1210 (37.8%: 430m-35% | 780f-65%), diabetes 320 (10%: 176m-55% 144f-45%).Results 900 pts were subjected to ESE: 540m 360w. Outcome at 1 year of CAD for mortality due to myocardial infarction, hospitalization for unstable angina major complications (CM): no pts. After ESE coronary angiography (CG) followed in 60 pts (7%): revascularizations (PTCA/CABG) 8 (1%: all men). ESE/CG correspondence in 100%. Comparison of CAD without revascularizations, ie diffuse atheromasia with sub-critical stenosis 35 (4%: 9m-25%, 26f-75%) all in primary evaluation without events and all hypertensive, evaluable as vasospastic ischemia (ie: x syndrome). Nobody pts was exposed to further radioactive stress procedures.Conclusions the functional test with ESE is confirmed as a valid tool, in term of cost-effectiveness also, in the screening and follow-up of CAD. Women and pts with multiple risk factors are different in the development of CAD. They are more exposed to the risk of an unappropriated and useless investigations, also radioactive. In general, ESE improves the prognosis and cost- effectiveness ratio in management of the pts with CAD.

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