Recent epidemiological trends in extrapulmonary TB in Galicia, Spain

2021 ◽  
Vol 25 (5) ◽  
pp. 373-381
Author(s):  
L. Ferreiro ◽  
A. Ruano-Raviña ◽  
R. Otero-Mallo ◽  
C. Pou-Álvarez ◽  
V. Riveiro-Blanco ◽  
...  
Keyword(s):  
Retrospective Cohort ◽  
Prevention And Control ◽  
Extrapulmonary Tuberculosis ◽  
Absolute Number ◽  
Incidence Rates ◽  
Age Group ◽  
Number Of Patients ◽  
Epidemiological Trends ◽  
And Control ◽  
Epidemiological Characteristics

OBJECTIVE: To describe the epidemiological trends and characteristics of extrapulmonary tuberculosis (EPTB) in Galicia, Spain, from 2000 to 2019.METHODS: This was a retrospective cohort study based on data from the Galician TB information system.RESULTS: Of the total number of TB cases (n = 15,871), 5,428 (34.2%) had EPTB. The absolute number of cases and incidence of EPTB decreased dramatically (from 480 cases and 17.8 cases/100,000 in 2000, to 172 and 6.4 cases/100,000 in 2019, respectively), with a mean annual decrease of respectively 64% and 4.7% for absolute cases and incidence rates. The risk for EPTB was higher in men than in women (RR 3.86, 95% CI 3.66–4.07). The most frequent age group was 15–44 years (2,234 patients, 41.2%); overall reductions per age group were 82% (0–14 years), 75% (15–44 years), 44% (45–64 years) and 63% (≥65 years), with statistically significant differences. The most frequently locations were the pleura (1,916 cases; 35.3%) and the lymph nodes (1,504; 27.7%).CONCLUSION: The incidence of EPTB in Galicia has decreased significantly in the last 20 years. The epidemiological characteristics have not changed, except for the number of patients with risk factors. This improvement of EPTB epidemiological trends coincides with the implementation of the programme for the prevention and control of TB, which suggests that it has been very effective in the control of the EPTB.

scholarly journals Tuberculosis in Poland in 2017

2019 ◽  
pp. 211-226 ◽  
Author(s):  
Maria Korzeniewska- Koseła
Keyword(s):  
Pulmonary Tuberculosis ◽  
Incidence Rate ◽  
Prevention And Control ◽  
Incidence Rates ◽  
Age Group ◽  
Pulmonary Tb ◽  
Mdr Tb ◽  
Tuberculosis In Children ◽  
And Control ◽  
The Eu

AIM OF THE STUDY. To evaluate the main features of TB epidemiology in 2017 in Poland and to compare with the situation in the EU/EEA countries. METHODS. Analysis of case- based data on TB patients from National TB Register, data on anti-TB drug susceptibility testing results in cases notified in 2017, data from National Institute of Public Health- National Institute of Hygiene on cases of tuberculosis as AIDS-defining disease, data from Central Statistical Office on deaths from tuberculosis based on death certificates, data from ECDC report „European Centre for Disease Prevention and Control/WHO Regional Office for Europe. Tuberculosis surveillance and monitoring in Europe 2019-2017 data. Stockholm: European Centre for Disease Prevention and Control, 2019”. RESULTS. In 2017, 5 787 TB cases were reported in Poland. The incidence rate was 15.1 cases per 100 000, with large variability between voivodeships from 8.9 to 21.9 per 100 000. The mean annual decrease of TB incidence in 2013-2017 was 4.2%. In 2017, 5127 cases were newly diagnosed with no history of previous treatment i.e. 13.3 per 100 000. 660 cases i.e. 1.7 per 100 000 – 11.4% of all registered subjects were previously treated for tuberculosis. In 2017, the number of all pulmonary tuberculosis cases was 5 531 i.e. 14.4 per 100 000. Pulmonary cases represented 95.6% of all TB cases. In 2017, 256 extrapulmonary TB cases were found. In the whole country there were 68 pediatric cases of tuberculosis. TB in children represented 1.2% of all cases notified in Poland in 2017. The incidence rates of tuberculosis were growing along with the age group from 1.2 per 100 000 among children to 25.6 per 100 000 among subjects in the age group 45-64 years (the highest incidence rate). In 2017, the incidence rate in the age group ≥65 years was 22.6 per 100 000. The TB incidence among men i.e. 22.2 per 100.000 was 2.4 times higher than among women i.e. 8,4 per 100 000. The biggest difference in the TB incidence between the two sex groups occurred in persons aged 45 to 49 years – 36.1 vs. 8.1 and in age group 55- 59 years – 45.2 vs. 10.7. The TB incidence in rural population was lower than in urban, respectively 14.2 per 100.000 and 15.6 per 100 000. The number of all registered culture positive TB cases was 4 179. Pulmonary tuberculosis was bacteriologically confirmed in 4 057 subjects. Culture-confirmed cases represented 72.2% of all TB cases and 73.4% of all pulmonary TB cases. The number of smear-positive pulmonary TB cases reported in 2017 was 2 472 i.e. 6.4 per 100 000 accounting for 44.7% of all pulmonary TB cases and 60.9% of culture confirmed pulmonary TB cases.. TB was AIDS indicative disease in 16 subjects. In all patients with tuberculosis in Poland in 2017 there were 44 cases with MDR-TB (among them 12 foreigners) and 85 patients with resistance to isoniazid only, representing respectively 1.2% and 2.2% of cases with known DST results (DSTs were available in 90.5% of all cultureconfirmed TB cases). In 2017, there were 108 patients of foreign origin among all cases of tuberculosis in Poland. TUBERCULOSIS MORTALITY. There were 543 deaths due to tuberculosis reported in 2016 – 1.4 per 100 000; 526 people died from pulmonary and 17 from extrapulmonary tuberculosis. Mortality among males – 2.2 per 100 000 – was 3.7 X higher than among females – 0.6. 37.9% of all TB deaths were cases 65 years old and older – 3.3 per 100 000. In 2016, there was one death from tuberculosis in children and no deaths in adolescents. In 2016, tuberculosis represented 0.14% of total mortality in Poland and 28.1% of mortality from infectious diseases. CONCLUSIONS. In 2017, the incidence of tuberculosis in Poland was lower than in 2016. Despite a continuous decline it is still higher than the average in the EU/EEA countries. The highest incidence rates were observed in older age groups. The incidence in males was more than 2 times higher than in females. The impact of migration on the characteristics of tuberculosis in Poland is not substantial. In Poland, tuberculosis in children, tuberculosis in persons infected with HIV and MDR-TB is less common than the average in the EU/EEA countries.

scholarly journals Tuberculosis in Poland in 2018

2020 ◽  
pp. 239-257
Author(s):  
Maria Korzeniewska-Koseła
Keyword(s):  
Disease Prevention ◽  
Pulmonary Tuberculosis ◽  
Incidence Rate ◽  
Prevention And Control ◽  
Incidence Rates ◽  
Age Group ◽  
Pulmonary Tb ◽  
Mdr Tb ◽  
And Control ◽  
The Eu

AIM OF THE STUDY. To evaluate the main features of tuberculosis (TB) epidemiology in 2018 in Poland and to compare with the situation in the EU/EEA countries. METHODS. Analysis of case- based data on TB patients from National TB Register, data on anti-TB drug susceptibility testing results in cases notified in 2018, data from National Institute of Public Health- National Institute of Hygiene on HIV-positive subjects for whom TB was an AIDS-defining disease, data from Central Statistical Office on deaths from tuberculosis based on death certificates, data from the report „ European Centre for Disease Prevention and Control/WHO Regional Office for Europe. Tuberculosis surveillance and monitoring in Europe 2020- 2018 data. Stockholm: European Centre for Disease Prevention and Control, 2020”. RESULTS. In 2018, 5487 TB cases were reported in Poland. The incidence rate was 14.3 cases per 100000, with large variability between voivodeships from 7.3 to 23.4 per 100 000. The mean annual decrease of TB incidence in 2014- 2018 was 3.8%. In 2018, 4852 cases were newly diagnosed with no history of previous treatment i.e. 12.6 per 100 000. 635 cases i.e. 1.7 per 100 000 – 11.6% of all registered subjects were previously treated for tuberculosis. In 2018, the number of all pulmonary tuberculosis cases was 5224 i.e. 13.7 per 100000. Pulmonary cases represented 95.2% of all TB cases. In 2018, 243 extrapulmonary TB cases were found i.e. 0.6 per 100 000. In the whole country there were 52 pediatric cases of tuberculosis. TB in children represented 0.9% of all cases notified in Poland in 2018. The incidence rates of tuberculosis were growing along with the age group from 0.9 per 100 000 among children to 24.7 per 100 000 among subjects in the age group 45-64 years (the highest incidence rate). In 2018, the incidence rate in the age group ≥65 years was 21.3 per 100 000. The TB incidence among men i.e. 21.0 per 100 000 was 2.6 times higher than among women i.e. 8.0 per 100 000. The biggest difference in the TB incidence between the two sex groups occurred in persons aged 55 to 59 years – 44.9 vs. 9.8 and in age group 60- 64 years – 43.7 vs. 10.2. The TB incidence in rural population was lower than in urban, respectively 13.4 per 100 000 and 14.9 per 100 000. The number of all registered culture positive TB cases was 4075. Pulmonary tuberculosis was bacteriologically confirmed in 3935 subjects. Cases confirmed by culture represented 74.3% of all TB cases and 75.3% of all pulmonary TB cases. The number of smear-positive pulmonary TB cases reported in 2018 was 2324 i.e. 6.1 per 100 000 accounting for 44.3% of all pulmonary TB cases and 59.1% of pulmonary TB cases confirmed by culture. In all patients with tuberculosis in Poland in 2018 there were 48 cases with MDR-TB (among them 14 foreigners) and 83 patients with resistance to isoniazid only, representing respectively 1.3% and 2.2% of cases with known DST results (DSTs were available in 90.7% of all culture-confirmed TB cases). In 2018, there were 97 patients of foreign origin among all cases of tuberculosis in Poland. TB was AIDS-indicative disease in 14 subjects with HIV co-infection. There were 490 deaths due to tuberculosis reported in 2017 – 1.3 per 100 000; 468 people died from pulmonary and 22 from extrapulmonary tuberculosis. Mortality among males – 2.1 per 100 000 – was 3.6 X higher than among females – 0.5. 40.2% of all TB deaths were cases 65 years old and older – 3.1 per 100 000. In 2017, there was no death from tuberculosis in children and no deaths in adolescents. In 2017, tuberculosis represented 0.1% of total mortality in Poland and 25.4% of mortality from infectious and parasitic diseases. CONCLUSIONS. In 2018, the incidence of tuberculosis in Poland was lower than in 2017. Despite a continuous decline it is still higher than the average in the EU/EEA countries. The highest incidence rates were observed in older age groups. The participation of pediatric cases is smaller than average in the EU/EEA countries. The incidence in males was more than 2 times higher than in females. The impact of migration on the characteristics of tuberculosis in Poland is not substantial. In Poland, MDR-TB is less common than the average in the EU/EEA countries.

scholarly journals Epidemiological Characteristics and Coping Strategies of COVID-19 in Shandong Province, China

2020 ◽  
Author(s):  
Muye Ma ◽  
Wenqiang Yin ◽  
Gejin Wang ◽  
Dahai Yu ◽  
Jinqiang Ma
Keyword(s):  
Coping Strategies ◽  
Prevention And Control ◽  
Early Period ◽  
Shandong Province ◽  
Cumulative Number ◽  
Incidence Trends ◽  
Number Of Patients ◽  
The World ◽  
And Control ◽  
Epidemiological Characteristics

Abstract Background: The COVID-19 spread from Hubei Province to the whole country and even many countries in the world, which has greatly impacted the public health，economic and social development in China and the world. This study aims to investigate the epidemiological characteristics of COVID-19 in Shandong Province, analyze the incidence trends, and explore the coping strategies for providing the basis and reference for COVID-19 epidemic prevention and control. Methods: Descriptive analysis was performed for epidemiological characteristics of confirmed COVID-19 cases from Jan. 21, 2020 to Feb. 15, 2020, in Shandong Province, and the spatiotemporal distribution of confirmed cases was drawn. Results: As of Feb. 15, 2020, there were 537 confirmed cases in Shandong Province and the cumulative incidence was 0.53/100000. The daily number of new confirmed cases showed a trend of first increase and then decrease, and the increase rate of the cumulative confirmed cases showed a downward trend. The severe rate, critical rate, cured rate and fatality rate were 2.98%, 2.23%, 30.54%, and 0.37%. Confirmed cases were more Males than females, and the infected patients covered all age groups. The cumulative number of confirmed cases of the resident population in the province has gradually exceeded that of the population from other places to Shandong, and the number of patients who had a history of close contact with confirmed cases has significantly increased over time. Qingdao had the largest number of confirmed cases. Conclusions: Our findings analyzed the early period of the epidemic in Shandong Province, which provide a novel insight for epidemic prevention and control.

scholarly journals Mumps epidemic in orthodox religious low-vaccination communities in the Netherlands and Canada, 2007 to 2009

2011 ◽  
Vol 16 (41) ◽  
Author(s):  
C C Wielders ◽  
R S van Binnendijk ◽  
B E Snijders ◽  
G A Tipples ◽  
J Cremer ◽  
...  
Keyword(s):  
General Practitioner ◽  
The Netherlands ◽  
Prevention And Control ◽  
Mumps Virus ◽  
Data Sources ◽  
Epidemic Strain ◽  
Vaccine Preventable Diseases ◽  
Laboratory Confirmation ◽  
And Control ◽  
Epidemiological Characteristics

We assessed the epidemiological characteristics of a mumps virus epidemic (genotype D) that occurred in the Netherlands between August 2007 and May 2009 and its association with a subsequent mumps outbreak in Canada. In the Netherlands, five data sources were used: notifications (only mandatory since the end of 2008) (56 cases), laboratory confirmation data (177 cases), a sentinel general practitioner (GP) database (275 cases), hospitalisation data (29 cases) and weekly virological reports (96 cases). The median age of cases in the notification, laboratory and GP databases ranged from 13 to 15 years. The proportion of cases that were unvaccinated ranged from 65% to 85% in the notification, laboratory and GP databases. Having orthodox Protestant beliefs was the main reason for not being vaccinated. In Canada, a mumps virus strain indistinguishable from the Dutch epidemic strain was detected between February and October 2008 in an orthodox Protestant community with historical and family links to the affected community in the Netherlands, suggesting that spread to Canada had occurred. Prevention and control of vaccine-preventable diseases among population subgroups with low vaccination coverage remains a priority.

scholarly journals Knowledge Enhancement about COVID-19 Prevention on Community with Webinar Program

2021 ◽  
Vol 5 (1) ◽  
pp. 103
Author(s):  
Ratih Damayanti
Keyword(s):  
Community Participation ◽  
Prevention And Control ◽  
P Value ◽  
Public Knowledge ◽  
Age Group ◽  
Community Groups ◽  
Public Facilities ◽  
Knowledge Enhancement ◽  
And Control ◽  
At Home

COVID-19 is increasingly difficult to control. There is evidence of an increase in cases during the beginning of December. There needs to be community participation in prevention and control efforts anywhere (including at home, public facilities and workplaces). Webinars are a method that can be used during a pandemic to increase public knowledge. In this activity, the results showed that some of the participants were female in the age group less than 30 years old with status as students. There was a significant increase in knowledge (p-value = 0.000) of community groups who were provided with counseling through webinars of 9.17 points. It is necessary to expand the reach of people who get counseling through webinars so that information or knowledge about the prevention and handling of COVID-19 can be widely spread throughout Indonesia. 

Epidemiological characteristics and clinical analyses of chronic cutaneous wounds of inpatients in China: Prevention and control

2020 ◽  
Vol 28 (5) ◽  
pp. 623-630
Author(s):  
Biao Cheng ◽  
Yufeng Jiang ◽  
Xiaobing Fu ◽  
Daifeng Hao ◽  
Hongwei Liu ◽  
...  
Keyword(s):  
Prevention And Control ◽  
Cutaneous Wounds ◽  
And Control ◽  
Epidemiological Characteristics

scholarly journals Pulmonary Versus Extrapulmonary Tuberculosis Associated Factors: A Case-Case Study

2019 ◽  
Vol 12 ◽  
pp. 117863611984036 ◽  
Author(s):  
Alberto Arnedo-Pena ◽  
Maria Angeles Romeu-Garcia ◽  
Noemi Meseguer-Ferrer ◽  
Iraya Vivas-Fornas ◽  
Ana Vizcaino-Batllés ◽  
...  
Keyword(s):  
Associated Factors ◽  
Extrapulmonary Tuberculosis ◽  
Incidence Rates ◽  
Epidemiological Surveillance ◽  
Logistic Regression Models ◽  
Control And Prevention ◽  
Epidemiological Characteristics ◽  
Microbiological Confirmation ◽  
Selection Of

Background: Tuberculosis (TB) incidence remains low in health departments of Castellon and La Plana-Vila-real, but TB elimination is challenging. The objective of this study was to estimate associated factors of pulmonary tuberculosis (PTB) compared with extrapulmonary tuberculosis (ETB) and investigate epidemiological characteristics of these pathologies to orient control and prevention actions. Materials and Methods: A prospective case-case study was implemented by comparing PTB and ETB incidences during 2013-2016 from notification reports, epidemiological surveillance, and microbiological results of hospitals’ laboratories Hospital General Castellon and La Plana-Vila-Real in the province of Castellon of Valencia region in Spain. In this design, cases were patients with PTB and controls were patients with ETB. Directed acyclic graph approach was used for selection of potential risk and confounding factors. Adjusted odds ratios (AORs) were estimated by logistic regression models. Results: The study included 136 patients with PTB and 57 patients with ETB, with microbiological confirmation of 93.4% and 52.6%, and the annual median of incidence rates were 7.5 and 3.1 per 100 000 inhabitants, respectively. In general, patients with PTB were younger with higher male proportion than patients with ETB. Risk factors of PTB were smoking tobacco (AOR = 3.98; 95% confidence interval [CI] = 1.66-9.56), social problems (social marginalization, homeless, residence in shelters for the poor, or stay in prison) (AOR = 3.39; 95% CI = 1.05-10.94), and contact with patients with TB (AOR = 2.51; 95% CI = 1.06-5.95). No-smoking tobacco and no-drug abuse interaction decrease PTB risk (AOR = 0.27; 95% CI = 0.12-0.64). From these results, specific measures of health promotion and prevention can be addressed. Conclusions: The estimated associated factors of PTB may be prevented, and it was demonstrated that the case-case design is useful in the study of TB.

scholarly journals A Descriptive Review of Selected Nonviral Enteric Illnesses Reported in Children in Quebec between 1999 and 2006

2010 ◽  
Vol 21 (2) ◽  
pp. e92-e98 ◽  
Author(s):  
Henri Kaboré ◽  
Pascal Michel ◽  
Patrick Levallois ◽  
Pierre Déry ◽  
Pierre Payment ◽  
...  
Keyword(s):  
Prevention And Control ◽  
Late Summer ◽  
Incidence Rates ◽  
Control Measures ◽  
Common Causes ◽  
Prevention And Control Measures ◽  
One Year ◽  
And Control ◽  
Different Sources ◽  
Geographical Characteristics

OBJECTIVE: To review the epidemiology of selected nonviral enteric illnesses reported in children in Quebec between 1999 and 2006.METHODS: Incidence rates were calculated to describe age, sex, temporal and geographical characteristics of the selected nonviral enteric cases reported in children who were between zero and four years of age. Standard descriptive methods were used to analyze the temporal and geographical distributions of the incidence rates.RESULTS: A total of 5068 cases were reported. Of these, three pathogens accounted for the majority of the infections:Giardia(32.52%),Salmonella(30.98%) andCampylobacter(30.82%).Salmonellawas most frequent in children younger than one year of age, whereas comparable incidence rates for the three pathogens were calculated for children between one and four years of age. ForGiardia, the geographical distributions showed that the highest rates were in areas with more than 100,000 inhabitants (except Montreal, Quebec); forSalmonella, the highest rates were in Montreal; and forCampylobacter,the highest rates were in areas with fewer than 10,000 inhabitants. No detectable trends were seen over the study period for the three pathogens. Seasonal summer peaks were noted forSalmonellaandCampylobacter, contrasting with late summer to early autumn peaks forGiardia.CONCLUSION: Findings suggest thatGiardia,SalmonellaandCampylobacterwere the most common causes of nonviral enteric illnesses reported in children in Quebec.Giardiacases seemed to arise from different sources and transmission routes than the other two pathogens. Characteristics specific toCampylobacterinfections in children, namely its predominance in areas with low population densities, and toSalmonellainfections, namely predominance in the Greater Montreal area, should be further investigated to better guide prevention and control measures.

scholarly journals Non-melanoma skin cancer in Serbia (1999-2015) -the need for national prevention and control strategy

2020 ◽  
Vol 77 (11) ◽  
pp. 1154-1160
Author(s):  
Danijela Ilic ◽  
Goran Videnovic ◽  
Ruzica Kozomara ◽  
Sonja Radakovic ◽  
Zoran Vlahovic ◽  
...  
Keyword(s):  
Incidence Rate ◽  
Control Strategy ◽  
Prevention And Control ◽  
Incidence Rates ◽  
Health Concern ◽  
Preventive Strategy ◽  
Non Melanoma Skin Cancer ◽  
National Prevention ◽  
And Control ◽  
Melanoma Skin

Background/Aim. Non-melanoma skin cancers (NMSC) are ones of the most rapidly increasing cancers worldwide. Although NMSCs have a relatively low mortality rate, they are an important public health concern and the most costly cancers in many countries. The two main objectives in this study were: first, to analyze the trend of age-standardized incidence rate of NMSCs in Serbia and second, to assess the need for national prevention and control strategy based on analyzed trend. Methods. From the Serbian Cancer Registry, we extracted all cases of NMSCs registered in central Serbia from January 1, 1999 to December 31, 2015. Joinpoint regression analysis was used to define trends and annual percentage change (APC). Results. NMSCs significantly increased for both genders with APC of +2.32% (p < 0.001). Significantly increasing trend of incidence rates was higher in women (APC, +2.63%; p < 0.0001) than in men (APC, +2.01%; p < 0.001). Conclusion. Our results show a continuously increasing incidence rate of NMCS in Serbia. Without the national preventive strategy, current sporadic activities are highly unlikely to result in reducing the growing trends

scholarly journals Characteristics of confirmed coronavirus disease cases at the south campus of Shanghai East Hospital: A retrospective study

2020 ◽  
Author(s):  
Chenghui Fan ◽  
Lihong Qu ◽  
Zhongliang Guo ◽  
Jianhua Zhang ◽  
Jun Wang ◽  
...  
Keyword(s):  
Outpatient Clinic ◽  
Prevention And Control ◽  
Laboratory Tests ◽  
Epidemic Spread ◽  
The South ◽  
Ct Findings ◽  
Laboratory Results ◽  
Returning To Work ◽  
And Control ◽  
Epidemiological Characteristics

Abstract Background: A fever outpatient clinic at the south campus of Shanghai East Hospital (SEH) openedin response to the coronavirus disease (COVID-19) outbreak. We analyzed the data of all 11,972patients who visited the fever clinic and the 29 confirmed COVID-19 cases to determine the clinical and epidemiological characteristics of confirmed COVID-19 cases diagnosed at SEH.Methods: Data were collected from all fever outpatient clinic patients between January 23 and September 30, 2020. We compared the characteristics of confirmed patients, including age, occupation, area, symptoms, laboratory results, and computed tomography (CT) findings, according to month.Results: By September 30, 2020, 11,972 patients, including 29 (0.24%) confirmed COVID-19 cases, visited the clinic. Four of five confirmed domestic cases identified during January–February 2020 were from Wuhan (mainly elderly retirees and local employees), Hubei. After the epidemic spread internationally, all 22 confirmed cases identified during March–April 2020 were individuals who returned from abroad. They were predominantly young Chinese international students. The sporadic two confirmed cases during May–September 2020 included an employee returning to work from Hubei and an Indian servant from abroad. Symptoms, laboratory tests, and CT findings were consistent with previous reports of COVID-19-positive cases.Conclusions: The characteristics of confirmed COVID-19 cases at SEH varied among different periods in response to the spread of the pandemic. However, due to the effective early isolation and quarantine measures, no outbreak occurred in SEH, which contributed to the prevention and control of the epidemic in Shanghai.

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