METABOLIC RESPONSES TO HIGH-SPEED TOTAL-BODY WORKOUTS

2014 ◽  
Vol 18 (4) ◽  
pp. 185-191 ◽  
Author(s):  
Steve W. Davison ◽  
Bill V. Rumpler ◽  
Amanda G. Barbosa ◽  
Evelyn V. Gutierrez ◽  
John F. Caruso
2002 ◽  
Vol 205 (18) ◽  
pp. 2875-2884 ◽  
Author(s):  
James C. Liao

SUMMARYThe Atlantic needlefish (Strongylura marina) is a unique anguilliform swimmer in that it possesses prominent fins, lives in coastal surface-waters, and can propel itself across the surface of the water to escape predators. In a laboratory flow tank, steadily swimming needlefish perform a speed-dependent suite of behaviors while maintaining at least a half wavelength of undulation on the body at all times. To investigate the effects of discrete fins on anguilliform swimming, I used high-speed video to record body and fin kinematics at swimming speeds ranging from 0.25 to 2.0 Ls-1 (where L is the total body length). Analysis of axial kinematics indicates that needlefish are less efficient anguilliform swimmers than eels, indicated by their lower slip values. Body amplitudes increase with swimming speed, but unlike most fishes, tail-beat amplitude increases linearly and does not plateau at maximal swimming speeds. At 2.0 Ls-1, the propulsive wave shortens and decelerates as it travels posteriorly, owing to the prominence of the median fins in the caudal region of the body. Analyses of fin kinematics show that at 1.0 Ls-1 the dorsal and anal fins are slightly less than 180° out of phase with the body and approximately 225° out of phase with the caudal fin. Needlefish exhibit two gait transitions using their pectoral fins. At 0.25 L s-1, the pectoral fins oscillate but do not produce thrust, at 1.0 L s-1 they are held abducted from the body,forming a positive dihedral that may reduce rolling moments, and above 2.0 L s-1 they remain completely adducted.


Heart ◽  
2018 ◽  
Vol 104 (20) ◽  
pp. 1706-1706 ◽  
Author(s):  
Jerrold Spapen ◽  
Stijn Lochy ◽  
Vincent Michiels

Clinical introductionA man in his late 40s presented with severe chest pain and progressive dyspnoea after hitting a tree at high speed during a bike ride in the woods. On admission, the patient appeared agitated, pale and sweaty. Core temperature was 35.5°C, respiratory rate 35/min and blood pressure 90/50 mm Hg with a regular pulse at 110 beats/min. Physical examination revealed multiple sternal bruises, distended jugular veins and muffled heart sounds (figure 1A). Lactate level was 4.4 mmol/L (normal <2.0 mmol/L) and high-sensitivity cardiac troponin T 0.142 mcg/L (normal <0.005 mcg/L). An ECG and a total body CT scan were performed (figure 1B,C).Figure 1(A) Multiple sternal bruises. (B) ECG on admission. (C) Thoracic CT.Question:  What is the most likely diagnosis?Inferior myocardial infarction with right ventricular involvement.Cardiac contusion with tamponade.Commotio cordis.Aortic laceration.


1994 ◽  
Vol 72 (8) ◽  
pp. 1420-1425 ◽  
Author(s):  
Thomas A. Churchill ◽  
Kenneth B. Storey

The metabolic responses by the liver to the evaporative loss of up to 60% of total body water were quantified in spring-collected wood frogs, Rana sylvatica, a freeze-tolerant species. Dehydration stimulated rapid hyperglycemia, liver glucose levels rising 3.8-fold to 90 nmol/mg protein (9.9 μmol/g wet mass) by the time that 10% of total body water had been lost. Glucose accumulation occurred at the expense of liver glycogen reserves, which fell over the course of dehydration, and was supported by a 5.8-fold increase in the activity of glycogen phosphorylase a in the liver, made up of increases in both the total phosphorylase activity expressed and the percentage of the enzyme in the active form. Analysis of changes in the levels of glycolytic intermediates in the liver over the course of dehydration showed sharp increases in glucose-6-phosphate and fructose-6-phosphate during the period of active glucose synthesis but no change in the levels of fructose-1,6-bisphosphate or triose phosphates. This indicated that an inhibitory block on glycolysis at the phosphofructokinase reaction helped to promote the diversion of glycogenolysis into glucose export. When water loss exceeded 10%, cellular energetics were affected; ATP levels fell progressively between 25 and 60% dehydration, but a concomitant drop in the total adenylate pool held the energy charge stable at 0.7–0.8 up to 35% dehydration. At extreme dehydration (50 and 60%), metabolic indicators of hypoxia stress appeared in the liver: lactate accumulated and the energy charge fell. The data show that a primary response to whole-body dehydration in wood frogs is the activation of liver glucose synthesis and this suggests that the production of glucose as a cryoprotectant during freezing in this species is probably derived from a pre-existing amphibian volume-regulatory response to dehydration.


2018 ◽  
Vol 24 (1) ◽  
pp. 57-59
Author(s):  
Caggiari Gianfilippo ◽  
Mosele Giulia Raffaella ◽  
Puddu Leonardo ◽  
Spiga Mauro ◽  
Doria Carlo

Fracture-dislocation of the humeral head with intrathoracic migration is extremely rare. In our study we describe the case of a 23-year-old man who was admitted to the emergency clinic of our hospital, after being injured in a high-speed motor vehicle accident. The patient presented in a state of hemorrhagic shock and severe respiratory disease. Chest radiography showed fracture of the right humeral head and the presence of a round radio-density area resting on the diaphragm right hemithorax. The total body computed tomography scan revealed a right pneumothorax related to the presence in the chest cavity of the fractured humeral head, longitudinal fracture of the sacrum, and diastasis of the symphysis pubis. After an initial hemodynamic stabilization the patient underwent surgical excision of the humeral head and its replanting. It is important after airway management and the use of diagnostic imaging, the treatment of any injuries associated with the trauma.


Author(s):  
S. Phyllis Steamer ◽  
Rosemarie L. Devine

The importance of radiation damage to the skin and its vasculature was recognized by the early radiologists. In more recent studies, vascular effects were shown to involve the endothelium as well as the surrounding connective tissue. Microvascular changes in the mouse pinna were studied in vivo and recorded photographically over a period of 12-18 months. Radiation treatment at 110 days of age was total body exposure to either 240 rad fission neutrons or 855 rad 60Co gamma rays. After in vivo observations in control and irradiated mice, animals were sacrificed for examination of changes in vascular fine structure. Vessels were selected from regions of specific interest that had been identified on photomicrographs. Prominent ultrastructural changes can be attributed to aging as well as to radiation treatment. Of principal concern were determinations of ultrastructural changes associated with venous dilatations, segmental arterial stenosis and tortuosities of both veins and arteries, effects that had been identified on the basis of light microscopic observations. Tortuosities and irregularly dilated vein segments were related to both aging and radiation changes but arterial stenosis was observed only in irradiated animals.


Author(s):  
E.D. Wolf

Most microelectronics devices and circuits operate faster, consume less power, execute more functions and cost less per circuit function when the feature-sizes internal to the devices and circuits are made smaller. This is part of the stimulus for the Very High-Speed Integrated Circuits (VHSIC) program. There is also a need for smaller, more sensitive sensors in a wide range of disciplines that includes electrochemistry, neurophysiology and ultra-high pressure solid state research. There is often fundamental new science (and sometimes new technology) to be revealed (and used) when a basic parameter such as size is extended to new dimensions, as is evident at the two extremes of smallness and largeness, high energy particle physics and cosmology, respectively. However, there is also a very important intermediate domain of size that spans from the diameter of a small cluster of atoms up to near one micrometer which may also have just as profound effects on society as “big” physics.


Author(s):  
N. Yoshimura ◽  
K. Shirota ◽  
T. Etoh

One of the most important requirements for a high-performance EM, especially an analytical EM using a fine beam probe, is to prevent specimen contamination by providing a clean high vacuum in the vicinity of the specimen. However, in almost all commercial EMs, the pressure in the vicinity of the specimen under observation is usually more than ten times higher than the pressure measured at the punping line. The EM column inevitably requires the use of greased Viton O-rings for fine movement, and specimens and films need to be exchanged frequently and several attachments may also be exchanged. For these reasons, a high speed pumping system, as well as a clean vacuum system, is now required. A newly developed electron microscope, the JEM-100CX features clean high vacuum in the vicinity of the specimen, realized by the use of a CASCADE type diffusion pump system which has been essentially improved over its predeces- sorD employed on the JEM-100C.


Author(s):  
Vivian V. Yang ◽  
S. Phyllis Stearner

The heart is generally considered a radioresistant organ, and has received relatively little study after total-body irradiation with doses below the acutely lethal range. Some late damage in the irradiated heart has been described at the light microscopic level. However, since the dimensions of many important structures of the blood vessel wall are submicroscopic, investigators have turned to the electron microscope for adequate visualization of histopathological changes. Our studies are designed to evaluate ultrastructural changes in the mouse heart, particularly in the capillaries and muscle fibers, for 18 months after total-body exposure, and to compare the effects of 240 rad fission neutrons and 788 rad 60Co γ-rays.Three animals from each irradiated group and three control mice were sacrificed by ether inhalation at 4 days, and at 1, 3, 6, 12, and 18 months after irradiation. The thorax was opened and the heart was fixed briefly in situwith Karnofsky's fixative.


Author(s):  
William Krakow

In the past few years on-line digital television frame store devices coupled to computers have been employed to attempt to measure the microscope parameters of defocus and astigmatism. The ultimate goal of such tasks is to fully adjust the operating parameters of the microscope and obtain an optimum image for viewing in terms of its information content. The initial approach to this problem, for high resolution TEM imaging, was to obtain the power spectrum from the Fourier transform of an image, find the contrast transfer function oscillation maxima, and subsequently correct the image. This technique requires a fast computer, a direct memory access device and even an array processor to accomplish these tasks on limited size arrays in a few seconds per image. It is not clear that the power spectrum could be used for more than defocus correction since the correction of astigmatism is a formidable problem of pattern recognition.


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