scholarly journals Serum Hepcidin Hormone Level and Its Genes Polymorphism

2021 ◽  
Author(s):  
Safa A. Faraj ◽  
Naeem M. Al-Abedy

This chapter sheds light on hepcidin, historical view of hepcidin, and the time of its discovery in the first section. Then this chapter gives information about the genetic aspect and the importance of gene knowledge of hepcidin in explaining many disorders in human beings, supported by illustration figures. The regulation of iron in the human body as an essential function of hepcidin is discussed in this chapter. Examples of the genes of hepcidin (HAMP and HFE) are highlighted in detail as they are essential in regulating iron as well as discussing the genetic mutations that occur in these genes and their medical and clinical impacts for many diseases such as thalassemia. Finally, the inherited disorders related to hepcidin that lead to genetic diseases are discussed.

2021 ◽  
Vol 3 (3) ◽  
pp. 407-419
Author(s):  
Makmudi Makmudi

Man consists of two elements, namely body and spirit, so that human beings are jasiman and ruhiyah at once. Hummans are also part of one element of the elements that exist in an educational process. Three element include the soul, the mind, the heart, and the human body. Humman and education, can not be separated from each other. Both are an interconnected entity, human as the perpetrator and education as a syistem in the process to achieve the goal of education itself.  Mental health education requires alignment and harmony in various stages and sectors as well as attention to the three elements that exist in the human self that is the physical element (psychomotor) which includes body building, skill (skill) and sexual education, the spiritual element (affective) which includes the formation of faith, and iradah (the will), the element of reason (cognitive) which includes the coaching of intelligence and the provision of knowledge. The purpose of writing this research is to know and analyze thoughts about the concept of life education perspective Ibn Qayyim al-Jauziyyah. Soul education is considered successful, if one's soul has reached the degree of nafs muthmainnah, which has three main characteristics that mutually reinforce one another, namely; (1) a faithful soul to God, (2) a patient soul, (3) a soul that is self-serving to Allah (tawakal). Through the process of mental education which includes: the foundation of theology, the purpose of mental education, integrated curriculum / manhaj at-takamul, appropriate methods and applicable according to its stages, such as: takhliyah stages, tahliyah stages, muhasabah an-nafs, dzikrullah, and tahqiq 'ubudiyah. So that from the process will give birth ihsan attitude, and will increase the piety in worship, both related to God and those related to humans and the surrounding natural environment. Because, the essence of ihsan attitude itself is upholding 'ubudiyah.


2018 ◽  
Vol 07 (03) ◽  
pp. 176-178 ◽  
Author(s):  
Arushi Kumar ◽  
Raj Kumar

AbstractNeurosciences in Buddhist era was mainly based on power of mind and thoughts. It emphasized mainly about the power of mind, control of thoughts, purification, and modifications of erroneous thought process, which should result in truthful and correct practices and subsequent actions by human beings to remain happy. Buddhism believes that most diseases of human body are secondary to mind and that these can be healed by controlling the erroneous thoughts and practices of Dhamma. Though the treatment for neurologic disorders such as headache, stress, and anxiety was primitive, it was mainly based on purification of mind and righteous pathway of Dhamma followed by medicines, modification in dietary and other living habits, etc. Enough evidence (including operated case-based commentary) shows that cranial surgery was also performed following appropriate diagnosis. The concept of diagnosis, preoperative evaluation, explanation to the patient, operative procedure, perioperative care, and follow-up was also present in that era.


Fahm-i-Islam ◽  
2020 ◽  
Vol 3 (1) ◽  
pp. 19-38
Author(s):  
Dr. Zainab Ameen ◽  
Sana Zia

Like the limits of crime, crimes against human life and body are also very dangerous in terms of their effects, so the Qur'an has fixed their punishment for them. Islamic law has set specific punishments for it, and it does not allow any kind of crime to be reduced. These crimes have schakled the very basis of society and they have to be dealt with severely. The basic elements of society are the need to protect the structures on which the lives and deaths of society depend. These crimes can be basically divided into two types: 1.Crimes against human beings (e.g. murder) 2.Crimes against the human body. There is a long way to go around, and in the meantime, this kind of research is needed, the seriousness of which is far greater than the rest of researches. This article examined the crimes against humanity in the light of Islamic law.


Author(s):  
Azhin T. Sabir

Introduction: Nowadays human gait identification/recognition is available in a variety of applications due to rapid advances in biometrics technology. This makes them easier to use for security and surveillance. Due to the rise in terrorist attacks during the last ten years research has focused on the biometric traits in these applications and they are now capable of recognising human beings from a distance. The main reason for my research interest in Gait biometrics is because it is unobtrusive and requires lower image/video quality compared to other biometric traits. Materials and Methods: In this paper we propose investigating Kinect-based gait recognition using non-standard gait sequences. This study examines different scenarios to highlight the challenges of non-standard gait sequences. Gait signatures are extracted from the 20 joint points of the human body using a Microsoft Kinect sensor. Results and Discussion: This feature is constructed by calculating the distances between each two joint points from the 20 joint points of the human body provided which is known as the Euclidean Distance Feature (EDF). The experiments are based on five scenarios, and a Linear Discriminant Classifier (LDC) is used to test the performance of the proposed method. Conclusions: The results of the experiments indicate that the proposed method outperforms previous work in all scenarios.


2018 ◽  
Vol 14 ◽  
pp. 187
Author(s):  
Emmanuela Kantzia

Philosopher and poet Demetrios Capetanakis (1912-1944) struggled withthe ideas of Hellenism and Greekness throughout his short life while moving across languages, cultures, and philosophical traditions. In one of his early essays, Mythology of the Beautiful (1937; in Greek), Hellenism is approached through the lens of eros, pain and the human body. Capetanakis distances himself both from the discourse put forth by the Generation of the Thirties and from the neo-Kantian philosophy of his mentors, and in particular Constantine Tsatsos, while attempting a bold synthesis of Platonic philosophy with the philosophy of despair (Kierkegaard, Shestov). By upholding the classical over and against the romantic tradition, as exemplified in the life and work of Johann Joachim Winckelmann, he seeks to present Hellenism not as a universal ideal, but as an individual life stance grounded on the concrete. His concern for the particular becomes more pronounced in a later essay, “The Greeks are Human Beings” (1941; in English), where, however, one senses a shift away from aesthetics, towards ethics and history.


Sapere Aude ◽  
2019 ◽  
Vol 10 (19) ◽  
pp. 31-42
Author(s):  
Maria Dulce Reis

Uma das últimas obras escritas por Platão, o Timeu, nos parece um dos textos mais ricos para identificarmos o estatuto das paixões na filosofia de Platão: a origem dessas paixões/afecções, suas propriedades, seu papel no equilíbrio psíquico e na condução das ações humanas. Tal riqueza, profundidade e extensão teórica constituiu grande parte de nossa tese de doutoramento, que visou demonstrar a articulação entre Psicologia, Ética e Política nos diálogos República, Timeu e Leis. No presente texto, nos limitaremos a apresentar nossa interpretação a respeito de passagens da cosmologia do Timeu dedicadas a tratar da constituição da unidade corpoalma humana, o que inclui suas afecções. Nosso recorte limita-se a mostrar que as afecções – próprias ao que há de apetitivo, irascível e racional na unidade corpoalma humana – decorrem da encarnação, e o seu direcionamento psíquico é capaz de conduzir os seres humanos à saúde ou à doença, à virtude ou ao vício.PALAVRAS-CHAVE: Platão. Filosofia Antiga. Psicologia. Páthos. ABSTRACT:One of the last works written by Plato, the Timaeus, seems to us one of the richest texts to identify the status of passions in Plato's philosophy: The origin of the passions/affections, their properties, their role in the psychic balance and the conduct of human actions. Such wealth, depth and theoretical extension constituted a large part of our doctoral thesis, that aimed to demonstrate the articulation between Psychology, Ethics, and Politics in the dialogues Republic, Timaeus, and Laws. In the present text, we shall confine ourselves to our interpretation of passages in the cosmology of the Timaeus devoted to the constitution of the human body-soul unity, which includes its affections. Our clipping is limited to showing that the affections - proper to that which is appetitive, irascible and rational in the human body-soul unity - elapsed from the incarnation and its psychic direction are capable of leading human beings to health or sickness, into virtue or vice.PALAVRAS-CHAVE: Platão. Filosofia Antiga. Psicologia. Páthos.


Author(s):  
Sidra Munir

When the antioxidants in our immune system cannot neutralize or convert Reactive oxygen species into safe molecules at the rate at which it is produced then this imbalance is termed as “oxidative stress”. It is related with a wide array of diseases that includes cancer, diabetes, cardiovascular diseases, hypertension etc. These ROS species however are utmost essential for the proper functioning of human body which are produced as a consequence of partial oxidation of cellular metabolism performing essential functions such as protein phosphorylation, activation of several transcriptional factors, apoptosis, immunity, and differentiation. The sources by which these are produced can be broadly classified are intrinsic and extrinsic sources. There are variety of natural antioxidant enzymes of human body that combat against this oxidative stress. The extrinsic sources of ROS include the use of natural plants, extracted flavonoids and vitamins. In this review we will briefly explain how the sources of ROS, its essential function in human body, its elevation and associated damage to organs and effect on various diseases, and a hope of finding a way of how this oxidative stress can be exploited for therapeutic potential.


2017 ◽  
Vol 42 (12) ◽  
pp. 3-4
Author(s):  
Jozef Zalot ◽  
Tadeusz Pacholczyk ◽  

In August 2017, researchers at the Oregon Health and Science University announced that they had successfully used a gene editing technique known as CRISPR-Cas9 to repair disease-causing genes in human embryos. Some members of the scientific and medical communities have hailed the development as a way to ensure that life- threatening diseases are not passed on to future generations. But is gene editing always a good thing? The Catholic Church encourages scientific research that is ethical and serves the human good. In the future, CRISPR may be used to treat people with serious genetic diseases, such as hemophilia and sickle-cell anemia. However, for research on human beings to be ethical, it must be strictly therapeutic and must respect the dignity and sacredness of human life. Gene-editing techniques raise profound ethical challenges in both respects.


Author(s):  
José M. Galván ◽  
Rocci Luppicini

What are the boundaries of humanity and the human body within our evolving technological society? Within the field of technoethics, inquiry into the origins of the species is both a biological and ethical question as scholars attempt to grapple with conflicting views of what it means to be human and what attributes are core to human beings within the era of human enhancement technologies. Based on a historical and conceptual analysis, this chapter uses a technoethical lens to discuss defining characteristics of the human species as homo technicus. Under this framework, both symbolic capacity and technical ability are assumed to be grounded within the free and ethical nature of human beings. Ideas derived from Modernity and Postmodernity are drawn upon to provide a more encompassing view of humans that accommodates both its technical and ethical dimensions as homo technicus.


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