scholarly journals Electro-Spinning and Electro-Spraying as Innovative Approaches in Developing of a Suitable Food Vehicle for Polyphenols-Based Functional Ingredients

2021 ◽  
Author(s):  
Mahmoud Ghorbani ◽  
Ricardo Santos Aleman

With recent advances in medical and nutrition sciences, functional foods and nutraceuticals fortified with natural polyphenols have received a lot of attention from both health professionals and the common population in the last few years since their chemical structure allows them to exert various health effects (e.g., antioxidant, anti-inflammatory, immune, antitumor and prebiotic properties). Nonetheless, there are several hurdles to applications of polyphenols in the food system. The most critical hurdle includes polyphenols’ tendency to lose their anti-oxidative properties or bioactive functionalities during food processing, as well as inclusion of poly-phenol compounds may impart an astringent or bitter taste, or introduce a degree of brown coloring causing serious sensorial impacts on food products. On this basis, interest has increased in understanding the development of new and efficient food vehicles as delivery systems for polyphenols-based functional ingredients. In this context, one approach that could augment the growth of polyphenols-based functional foods is electro-hydrodynamic processing, as the most versatile method to produce nanoscale fibers or particulates suitable for application in food technology by encapsulation to form nanoscale delivery systems.




Author(s):  
J. Robin Moon ◽  
Craig Willingham ◽  
Shqipe Gjevukaj ◽  
Nicholas Freudenberg

New York City was hit hard by the COVID-19 pandemic. Although the immediate health burden was devastating, we posit that its long-term impact will be even greater, because the rapid spread of COVID-19 both depended on and exacerbated other deep-seated inequities related to food and broader living conditions. Using the Bronx as a case study, we explore the intersection of the pandemic with two other persistent problems: food insecurity and diet-related diseases, a constellation we label the COVID-Food Syndemic. Syndemic theory focuses on the common causes and biological and social interactions between two or more health problems. We hypothesize that with its focus on the common social causes of ill health, this approach can inform and strengthen the synergies between community-based, activist-driven solutions and municipal government responses, thus reducing the burden of ill health in the Bronx. We suggest that combining these two approaches can more fully mobilize the social changes that are needed in the food system and beyond to interrupt the fundamental drivers of this syndemic and capitalize on the respective strengths of government, civil society, and activists.



Author(s):  
Caitlin Honan

The Common Market is a nonprofit regional food distributor with a mission to connect communities with good food from sustainable family farms. Outputs of their work include improved food security, farm viability, and community and ecological health. The nonprofit services communities in its three active regions—the Mid-Atlantic, the Southeast, and Houston, Texas—by delivering healthy farm food to the institutions that serve them: schools, hospitals, eldercare facilities, early childhood education centers, etc. As the COVID-19 pandemic struck the nation, it shut down some of the nonprofit’s con­ventional wholesale outlets and exposed and intensified the issue of food insecurity throughout the country. The food hub prepared to lean on its mission intensely and creatively under these unprece­dented circumstances. Poised to test the limits of a regional food system, The Common Market unveiled the resilient spirits of its team, its partners, and the family farms that make up its network. This essay highlights partnerships that ignited meaningful impact for their farmer partners and helped meet the needs of vulnerable populations amidst the pandemic. . . .



Author(s):  
Hao Li ◽  
Teng Wang ◽  
Yulin Hu ◽  
Jianfeng Wu ◽  
Paul Van der Meeren


2019 ◽  
pp. 97-124
Author(s):  
Allan V. Horwitz

From the beginning of the 20th century onward, Freud’s writings concentrated on elucidating the common processes—repression, the unconscious, childhood sexuality, and the libido—that gave rise to both normal and neurotic phenomena. World War I then turned his attention to external traumas and the role of the ego in mediating between the conflicting demands of the id on one side and the superego and civilization on the other. Freud’s lasting contribution to thinking about mental illness was to successfully expand the range of disorders well beyond conditions thought to have an organic basis or the psychoses. Neuroses resulted from interactions between individuals and their human environments: no physical defect needed to be present. Psychiatrists came to have legitimate claims to treat distressing states that had previously been viewed as purely psychogenic in nature and therefore outside of the medical or neurological realm. Moreover, his blurring of the boundaries between the neuroses and normality created a zone of ambiguity that mental health professionals came to exploit. They came to treat a vast expanse of common occurrences including interpersonal conflicts, the psychic results of traumas, and everyday problems of living.



Antioxidants ◽  
2020 ◽  
Vol 9 (8) ◽  
pp. 707 ◽  
Author(s):  
Silvana Alfei ◽  
Barbara Marengo ◽  
Guendalina Zuccari

Oxidative stress (OS), triggered by overproduction of reactive oxygen and nitrogen species, is the main mechanism responsible for several human diseases. The available one-target drugs often face such illnesses, by softening symptoms without eradicating the cause. Differently, natural polyphenols from fruits and vegetables possess multi-target abilities for counteracting OS, thus representing promising therapeutic alternatives and adjuvants. Although in several in vitro experiments, ellagitannins (ETs), ellagic acid (EA), and its metabolites urolithins (UROs) have shown similar great potential for the treatment of OS-mediated human diseases, only UROs have demonstrated in vivo the ability to reach tissues to a greater extent, thus appearing as the main molecules responsible for beneficial activities. Unfortunately, UROs production depends on individual metabotypes, and the consequent extreme variability limits their potentiality as novel therapeutics, as well as dietary assumption of EA, EA-enriched functional foods, and food supplements. This review focuses on the pathophysiology of OS; on EA and UROs chemical features and on the mechanisms of their antioxidant activity. A discussion on the clinical applicability of the debated UROs in place of EA and on the effectiveness of EA-enriched products is also included.



2015 ◽  
Vol 18 (3) ◽  
pp. 396 ◽  
Author(s):  
Mustafa Kotmakçı ◽  
Vildan Bozok Çetintaş

A new platform for drug, gene and peptide-protein delivery is emerging, under the common name of “extracellular vesicles”. Extracellular vesicles (EVs) are 30-1000 nm-sized cell-derived, liposome-like vesicles. Current research on EVs as nano-delivery systems for small-molecule drugs and genetic material, reveal that these tiny, biologically-derived vesicles carry a great potential to boost the efficacy of many therapeutic protocols. Several features of EVs; from efficacy to safety, from passive to active targeting ability, the opportunity to be biologically or chemically labelled, and most importantly, their eobiotic origin make them promising candidate for development of the next generation personalized nanomedicines. The aim of this article is to provide a view on the current research in which EVs are used as drug/genetic material delivery systems. Their application areas, drug loading and targeting strategies, and biodistribution properties are discussed.This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.



2018 ◽  
Vol 72 ◽  
pp. 1004-1017
Author(s):  
Bogusława Konopska ◽  
Krzysztof Gołąb ◽  
Katarzyna Juszczyńska ◽  
Jakub Gburek

Proteins are natural and safe substitutes of the synthetic polymers for the development of drug delivery systems (DDS). Few of proteins have been approved for drug delivery purposes by the United States Food and Drug Administration (FDA). Among them, albumin is the most explored carrier for synthesis of therapeutic nanoparticles. Its usefulness was determined by the common accessibility, biocompatibility and the feasibility of accumulation in tissues with increased metabolism. Albumin with its properties is particularly attractive carrier for anti-arthritis and anti-cancer drugs. It is mainly used to design delivery systems for poorly soluble substances with low permeability through biological membranes. The albumin nanoparticles are characterized by favourable pharmacokinetics, high drug delivery efficiency and low cytotoxicity. In addition, they are biodegradable, relatively easy to prepare and non-immunogenic. Interest in the exploration of clinical applications of albumin-based drug delivery carriers, especially for those at the nanoscale, has increased in recent years. A lot of research have been done to design multifunctional theranostic nanosystems that could be used for both imaging and cancer therapy. This article aims at providing an overview of already commercialized and just emerging applications of albumin-based nanosystems as drug delivery carriers.



2019 ◽  
Vol 7 (4) ◽  
pp. 119-130 ◽  
Author(s):  
Julia Behringer ◽  
Peter H. Feindt

The food democracy discourse has emerged as a normatively grounded critique of an increasingly transnational agri-food system and its dominant co-regulatory mode of governance, where private and public norms and standards interact with public policy and regulation in complex ways. Analyzing competing agri-food discourses through a legitimacy lens can contribute to understanding how authority is transferred from traditional, hierarchical and state-centered constellations to a range of novel agri-food governance arrangements. This article reconstructs and compares the legitimacy constructions articulated in the co-regulation and the food democracy discourses, generating three key findings: first, there are two distinct articulations of food democracy discourse, which we label liberal and strong food democracy; second, while conceptualizations of legitimacy in the liberal food democracy and the co-regulatory discourse share many commonalities, legitimacy in the co-regulatory discourse relies more heavily on output, while the liberal food democracy discourse is more sensitive to issues of input and throughput legitimacy; third, the strong food democracy discourse articulates a critical counter-model that emphasizes inclusive deliberation which in turn is expected to generate a shared orientation towards the common good and countervailing power.



2019 ◽  
Vol 23 (3) ◽  
Author(s):  
Janaina Pinto Janini ◽  
Rosangela da Silva Santos ◽  
Lívia Fajin de Mello dos Santos ◽  
Viviane de Melo Souza

Abstract Objective: To know the common sense of transsexual women in reaction to the transsexual process and to discuss the epistemological construction about the transsexuality and nursing in this process. Method: Qualitative research, carried out between May and June 2017, with 90 transsexual women attending a specialized center. Results: The common sense of the interviewees evidenced the transsexuality as an identity issue and not a disease, barriers to attendance in health demands and absence of the nursing professional. Discussion: The epistemological construction of the transsexuality takes place through science, which instrumentalized the Transsexual Process Policy and does not have the knowledge presented by the common sense of the users. Conclusion and implications for nursing practice: Science has a role to create order and practices from the refinement of common sense, but does not use the common sense of transsexual women in the epistemological construction of transsexuality, which compromises care and reinforces stereotyped and pathological character by health professionals. Science has the power to validate common sense, sedimenting the care to transsexual women, especially nursing practice. Nursing has the challenge of understanding issues related to transsexuality by articulating common sense with scientific knowledge.



Sign in / Sign up

Export Citation Format

Share Document