An Isolated Vertebral Metastasis of Urachal Adenocarcinoma

2004 ◽  
Vol 128 (9) ◽  
pp. 1043-1045 ◽  
Author(s):  
Sophia Taylor ◽  
Patrizia Bacchini ◽  
Franco Bertoni
Keyword(s):  
Differential Diagnosis ◽  
Biopsy Specimen ◽  
Clinical Findings ◽  
Thoracic Vertebra ◽  
Partial Cystectomy ◽  
Rare Tumor ◽  
Vertebral Metastasis ◽  
Metastatic Patterns ◽  
Urachal Adenocarcinoma

Abstract We describe a case of urachal adenocarcinoma arising in a 30-year-old woman. The patient underwent partial cystectomy. Three years later, she presented with an isolated metastasis to a thoracic vertebra, which was treated by vertebral corporectomy. Histologic findings are described, and the clinical findings, management, and metastatic patterns of this rare tumor, as well as the differential diagnosis on a biopsy specimen, are discussed.

scholarly journals A Rare Cause of Urachal Adenocarcinoma: Urachal Diverticle

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Tufan Çiçek ◽  
Umut Gönülalan ◽  
Gökçen Çoban ◽  
Hilal Erinanç ◽  
Murat Koşan
Keyword(s):  
Differential Diagnosis ◽  
Partial Cystectomy ◽  
Imaging Modalities ◽  
Prenatal Period ◽  
Pathologic Examination ◽  
Urachal Adenocarcinoma ◽  
Umbilical Ligament

Urachus is the remnant of the embryologic allantois and the fetal bladder, extending form the bladder roof to the umbilicus. It degenerates in the prenatal period into a tissue band known as the median umbilical ligament. Incomplete degeneration may lead to urachal diverticle development. It is difficult to diagnose unless it is considered in differential diagnosis and imaging modalities are employed. This paper describes a patient treated with partial cystectomy for urachal diverticle, and the pathologic examination revealed urachal adenocarcinoma.

scholarly journals Malignant Peripheral Nerve Sheath Tumor in the Nasal Cavity of a Neonate: A Case Report

2021 ◽  
pp. 014556132110141
Author(s):  
Xiufang Chi ◽  
Yue Wang ◽  
Haoming Yang ◽  
Cheng Xing ◽  
Jiamin Gan ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Peripheral Nerve ◽  
Nasal Cavity ◽  
Nerve Fibers ◽  
Nerve Sheath Tumor ◽  
Rare Tumor ◽  
Nasal Mass ◽  
Peripheral Nerve Sheath Tumor ◽  
Related Literature ◽  
Nerve Sheath

Malignant peripheral nerve sheath tumor (MPNST) is a rare tumor that can develop on the lining of nerves and within the network of nerve fibers in different organs, and it is commonly found in the head and neck, limbs, and trunk. These tumors can occur in patients of any age. They most commonly occur in adults aged 20 to 50 years; however, fewer cases of this tumor in children have been reported. To date, no neonatal case of MPNST in the nasal cavity has been reported. Here, we report the case of a 4-day-old female newborn who presented with a nasal mass that re-enlarged after surgery and was diagnosed as MPNST of the nasal cavity on the basis of pathological results. This is the first report of MPNST in the nasal cavity of a neonate. Differential diagnosis and treatment of nasal masses have been proposed in the related literature.

scholarly journals Surgical Approach to Splenic Hydatid Cyst: Single Center Experience

2013 ◽  
Vol 98 (4) ◽  
pp. 346-353 ◽  
Author(s):  
Cengiz Eris ◽  
Sami Akbulut ◽  
Mehmet Kamil Yildiz ◽  
Hasan Abuoglu ◽  
Mehmet Odabasi ◽  
...  
Keyword(s):  
Hydatid Cyst ◽  
Surgical Approach ◽  
Treatment Options ◽  
Clinical Findings ◽  
Partial Cystectomy ◽  
Diagnostic Methods ◽  
Septic Complications ◽  
Single Center Experience ◽  
Medicinal Treatment ◽  
Splenic Hydatid Cyst

Abstract The benefits and risks of surgery for splenic hydatid cyst (SHC) remain controversial. We aimed to share our experience about a surgical approach for SHC. Sixteen consecutive patients with SHC disease who underwent open splenectomy at our hospital between January 2006 and July 2012 were retrospectively evaluated. Data on the patients' demographic features, clinical findings, radiological and serological diagnostic methods, and surgical and medicinal treatment options were collected and used to generate descriptive profiles of diagnosis, treatment course, and outcome. The patient population was composed of 6 females and 10 males, with an age range of 18 to 79 years (mean age: 47.0 ± 18.0). Radiological examinations detected hydatid cysts in spleen alone (n = 7) or both spleen and liver (n = 9). Preoperative serological testing identified 13 of the patients as IHA positive. All except 1 patient received a 10- to 21-day preoperative course of albendazole therapy and all patients received vaccination 1 week prior to surgery. Seven patients underwent splenectomy. The remaining patients underwent splenectomy with partial cystectomy and omentopexy (n = 6), partial cystectomy and unroofing (n = 1), pericystectomy (n = 1), or pericystectomy with partial nephrectomy (n = 1). All except one patient received a 10- to 45-day postoperative course of albendazole. No patients developed serious complications or signs of recurrence during the follow-up. The clinical profile of SHC disease at our hospital includes diagnosis by radiological methods, splenectomy treatment by simple or concomitant procedures according to the patient's symptoms, cyst size, number and localization, and compression of adjacent organs, and adjunct vaccination to decrease risk of postoperative septic complications. This profile is associated with low risk of complications and high therapeutic efficacy.

scholarly journals Genetic testing for choroideremia

2017 ◽  
Vol 1 (s1) ◽  
pp. 26-28
Author(s):  
Andi Abeshi ◽  
Alessandra Zulian ◽  
Tommaso Beccari ◽  
Munis Dundar ◽  
Francesco Viola ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Clinical Trials ◽  
Optical Coherence Tomography ◽  
Differential Diagnosis ◽  
Clinical Utility ◽  
Scientific Literature ◽  
Genetic Test ◽  
Fundus Autofluorescence ◽  
Clinical Findings ◽  
Ophthalmological Examination

Abstract We studied the scientific literature and disease guidelines in order to summarize the clinical utility of the genetic test for choroideremia (CHM). CHM is an inherited X-linked recessive disorder associated with variations in the CHM gene. The overall prevalence of CHM varies from 1 in 50 000 to 1 in 100 000. Clinical diagnosis is based on clinical findings, ophthalmological examination, visual field, fundus autofluorescence, optical coherence tomography and electroretinography. The genetic test is useful for confirming diagnosis and for differential diagnosis, couple risk assessment and access to clinical trials.

Neonatal Adenovirus Infection: Four Patients and Review of the Literature

PEDIATRICS ◽  
1991 ◽  
Vol 87 (6) ◽  
pp. 890-896
Author(s):  
Mark J. Abzug ◽  
Myron J. Levin
Keyword(s):  
Differential Diagnosis ◽  
Clinical Findings ◽  
Adenovirus Infection ◽  
Review Of The Literature ◽  
Birth Canal ◽  
Maternal Illness ◽  
Epidemiologic Evidence ◽  
Major Mode ◽  
Mode Of Transmission ◽  
Virus Isolates

Four newborns with adenovirus infection are described, and the profile of neonatal adenovirus disease is outlined based on the cases of these newborns and nine previously described. Characteristic historical features included prolonged rupture of membranes, maternal illness, vaginal delivery, and onset of illness within the first 10 days of life. Clinical findings included lethargy, fever or hypothermia, anorexia, apnea, hepatomegaly, bleeding, and progressive pneumonia. Thrombocytopenia, coagulopathy, and hepatitis were typical laboratory manifestations. Illness was severe and generally unremitting; only two survivors have been reported. Pathologic changes were prominent in lung, liver, and brain. Virus isolates, predominantly serotypes 3, 7, 21, and 30 were obtained from multiple sites and organs. Epidemiologic evidence suggests that viral acquisition from the mother, perhaps via the birth canal, is a major mode of transmission. Neonatal adenovirus infection, which is frequently disseminated and generally fatal, should be considered in the differential diagnosis of neonatal sepsis and pneumonia.

scholarly journals Abdominal Cutaneous Nerve Entrapment Syndrome, Case Report and Diagnostic Evaluation

2019 ◽  
Vol 38 (02) ◽  
pp. 141-144
Author(s):  
Jose Fernando Guedes-Correa ◽  
Stephanie Oliveira Fernandes de Bulhões
Keyword(s):  
Neuropathic Pain ◽  
Differential Diagnosis ◽  
Case Report ◽  
Clinical Findings ◽  
Nerve Entrapment ◽  
Cutaneous Nerve ◽  
Noninvasive Treatment ◽  
Important Differential Diagnosis ◽  
Anterolateral Wall ◽  
Nerve Entrapment Syndrome

Abdominal cutaneous nerve entrapment is a rarely diagnosed condition that leads to intense neuropathic pain in the anterolateral wall of the abdomen. Generally, it is triggered by some factor implied in the increase of the pressure on the nerve in its passage by the abdominal wall. Its most important differential diagnosis is pain of visceral origin.We present a case in which the clinical findings confirmed on ultrasound and other imaging tests established the diagnosis and in which the noninvasive treatment was effective.

scholarly journals Intraoral Sebaceous Carcinoma: Case Report of a Rare Tumor Emphasizing the Histopathological Differential Diagnosis

2018 ◽  
Vol 2018 ◽  
pp. 1-6
Author(s):  
Manveen Kaur Jawanda ◽  
R. V. Subramanyam ◽  
Harshaminder Grewal ◽  
Chitra Anandani ◽  
Ravi Narula
Keyword(s):  
Differential Diagnosis ◽  
Oral Cavity ◽  
Sebaceous Carcinoma ◽  
Rare Tumor ◽  
Radiographic Findings ◽  
Case Presentation ◽  
Clinical Appearance ◽  
Cutaneous Malignancy ◽  
The Face ◽  
Rare Malignancy

Background. Sebaceous carcinoma (SC) is an uncommon cutaneous malignancy, usually occurring predominantly in the eyelids and only occasionally involving the oral cavity. Sebaceous carcinoma (SC) is a rare malignancy. Only 10 cases of sebaceous carcinoma of the oral cavity have been reported so far. Case Presentation. A 40-year-old female presented with a mass on the left side of the middle third of the face. Radiographic findings were inconclusive. Resection of the mass was consistent with the diagnosis of primary sebaceous carcinoma. Conclusion. Intraoral sebaceous carcinoma is uncommon. Due to its varied clinical appearance and presence of a diverse histopathologic appearance, the diagnosis is quite often confounding and elusive. Hence, it is imperative to familiarize oneself about various aspects of this rare tumor for earlier diagnosis, to improve the chances of patient’s survival.

scholarly journals Surgical management of urachal tumors: Can the umbilicus be sparred in localized disease?

Rare Tumors ◽  
2019 ◽  
Vol 11 ◽  
pp. 203636131984728
Author(s):  
Cristian Pavelescu ◽  
Alexandra Pavelescu ◽  
Cristian Surcel ◽  
Cristian Mirvald ◽  
Mario Alvarez-Maestro ◽  
...  
Keyword(s):  
Lymph Node ◽  
Surgical Treatment ◽  
Local Recurrence ◽  
Distant Metastasis ◽  
Lymph Node Involvement ◽  
Partial Cystectomy ◽  
En Bloc ◽  
Node Involvement ◽  
Urachal Adenocarcinoma

Urachal adenocarcinoma represents the third most common histological type of non-urotelial bladder cancer. A very low incidence of this disease and the lack of prospective studies have led to a rich and heterogeneous treatment history. Currently, the standard of care for these patients is represented by partial cystectomy en bloc with resection of the urachal ligament and total omphalectomy. The aim of this article is to present our experience and results in the management of patients with urachal adenocarcinoma. Between 2005 and 2015, 16 patients have undergone surgical treatment for urachal adenocarcinoma in “Fundeni” Clinical Institute and Madrid University Hospital “Infanta Sofia.” Partial cystectomy was performed in 11 (68.76%) patients, while radical cystectomy en bloc with omphalectomy was performed in 5 (31.25%) patients, which were not amendable to a limited resection. The Sheldon classification was used, as it provides appropriate disease staging and is the most commonly utilized. Postoperative pathological results showed that 7 (43.75%) patients had localized tumors, and more than one-third (37.5%) of the patients had locally advanced Sheldon III disease, while 3 patients had distant metastasis at the time of surgery. Lymph node involvement was present in 3 patients (18.75%). Mean follow-up time was 2.5 years, ranging from 4 months to 7.6 years. Three patients (18.75%) were lost to follow-up, without any documented signs of local or systemic recurrence and were cancer free at the time of the last evaluation. In cases with lymph node involvement, local recurrence or distant metastasis, patients underwent cisplatin- or 5-fluorouracil-based salvage chemotherapy. Surgical treatment represents the gold standard, while adjuvant chemotherapy has a limited impact on overall survival. The utility of navel resection is questionable due to the rarity of direct invasion or local recurrence.

scholarly journals Accidental transdermal methanol poisoning presenting to a regional emergency department

CJEM ◽  
2019 ◽  
Vol 21 (3) ◽  
pp. 435-437
Author(s):  
Chelsea R. Beaton ◽  
Clinton Meyer
Keyword(s):  
Emergency Department ◽  
Differential Diagnosis ◽  
Metabolic Acidosis ◽  
Laboratory Testing ◽  
Clinical Findings ◽  
Anion Gap ◽  
List Type ◽  
Emergency Physicians ◽  
Clinical Presentations ◽  
Learning Points

Learning Points:•Know and identify clinical presentations of toxic alcohols.•Understand the differential diagnosis of high anion gap metabolic acidosis.•Appreciate the importance of history and clinical findings in establishing methanol toxicity diagnoses, especially in centres where laboratory testing is unavailable.•Recognize the value of provincial poison centres in supporting emergency physicians in the diagnosis and management of poisonings and overdoses.

Sign in / Sign up

Export Citation Format

Share Document