scholarly journals Organosomatic indices and leukocyte formula of chub (Squalius cephalus L) from the Suturlija River

2020 ◽  
Vol 21 (4) ◽  
Author(s):  
Azra Bakrač ◽  
Subha Džafić ◽  
Radoslav Dekić ◽  
Irma Ičanović
Keyword(s):  
Blood Count ◽  
Condition Factor ◽  
Leukocyte Count ◽  
Total Leukocyte Count ◽  
Differential Blood Count ◽  
Length Standard ◽  
Organ Systems ◽  
Important Means ◽  
The Mean ◽  
Squalius Cephalus

Coefficients of organs, along with haematological characteristics, represent an important means of monitoring the health and condition of fish. Organosomatic indices show the state of organ systems and individual organs. They manifest as changes in size, which are reflected through a decrease or increase, under the influence of environmental factors. Chub individuals from the Suturlija River were used for analysis. The paper analyses the Fulton's condition factor, heart, liver, and spleen coefficients as a condition factor. Furthermore, the values ​​of total length, standard length, and body weight were determined for all individuals. Also, certain haematological parameters were analysed in the paper: total leukocyte count and differential blood count. A total of 19 chubs caught from the Suturlija River were analysed. The obtained result of Fulton's condition factor (1.53) indicates favourable habitats for chub individuals in the Suturlija River. The results of organosomatic indices are without major variations between individuals (CSI = 0.184, SSI = 0.992, HSI = 0.133). The mean leukocyte count was 45.857x109/l, with the highest proportion of lymphocytes in the differential blood count.

Haematology and Blood Chemistry of the Conscious Platypus, Ornithorhynchus anatinus (Shaw) (Monotremata: Ornithorhynchidae)

1984 ◽  
Vol 32 (5) ◽  
pp. 631 ◽  
Author(s):  
RJ Whittington ◽  
TR Grant
Keyword(s):  
Leukocyte Count ◽  
New South ◽  
Blood Chemistry ◽  
Total Leukocyte Count ◽  
Cell Parameters ◽  
Sexual Dimorphisms ◽  
South Wales ◽  
Ornithorhynchus Anatinus ◽  
Serum Biochemical ◽  
The Mean

Blood was collected from a bill sinus of nine conscious adult platypuses, Ornithorhynchus anatinus, caught in south-eastem New South Wales. Sexual dimorphisms were not found in the haematological and serum biochemical values measured. Results were compared with those obtained earlier from anaesthetized platypuses: ether anaethesia did not affect red cell parameters and the majority of biochemical values measured. It did, however, cause significant leukocytosis due to neutrophilia and monocytosis. The mean total leukocyte count in conscious platypuses was 28.63 X 10*9.1-�. The unusually high urea levels and low creatinine levels found in anaesthetized platypus were confirmed in this study (31.5 mmol.l-� and 26 �mol.l-� respectively). High values for erythrocyte count (9.96 X 10*12.l-�), packed cell volume (0.491.l-�) and haemoglobin (190 g.l-�) were found in conscious platypuses, confirming earlier findings and supporting the view that the erythrocyte parameters of the platypus show significant adaptations to hypoxia.

scholarly journals Evaluation of predictive value of total leukocyte count in acute serious bacterial infections in children 1 month to 5 years

2017 ◽  
Vol 4 (2) ◽  
pp. 415
Author(s):  
Dharmalingam A. ◽  
Vignesh C. ◽  
Raghupathy N. S. ◽  
Sowmiya M.
Keyword(s):  
Tract Infection ◽  
Antibiotic Therapy ◽  
Bacterial Infection ◽  
Leukocyte Count ◽  
Empiric Antibiotic Therapy ◽  
Total Leukocyte Count ◽  
Febrile Child ◽  
Group I ◽  
The Mean ◽  
Group 2

Background: Fever in a young child is a frequently encountered clinical problem with various causes. Most of them run a benign self-limiting course that requires only symptomatic treatment. However, in a few children the underlying etiology can be a life threatening serious bacterial infection (SBI). Early identification of SBI is warranted because of the need to start antibiotic therapy, often empirical, as soon as possible to prevent morbid sequela. Total leukocyte count (TLC) is with neutrophil predominance is considered to be a surrogate marker of a bacterial infection and facilitating decision - making regarding further evaluation and empiric antibiotic therapy. The purpose of this study was to determine the utility of leukocyte in predicting SBI in a young febrile child and to correlate the leukocyte count with non-serious infection.Methods: One fifty children, age of 1 month to 60 months with fever > 38°c are included and were analyzed for demographic details, presenting symptoms, physical examination findings, clinical diagnosis, total leukocyte count, peripheral smear study, blood culture, stool culture, CSF analysis, x-ray chest, abdominal ultrasound, CT-brain. Results: Out of 150 children included in the study, the mean age was 26.7±14.54 months and the average duration of fever was 4.3±1.02 days. The mean leukocyte count was 15016.43±5801.98 cells/cu.mm. 74 children had proven serious bacterial infection (49.3%) and were categorized in Group I and remaining non-serious infection were 50.66% are belonged to Group 2. Urinary tract infection and pneumonia were the most common SBI encountered (31/20/68.91%). The highest TLC counts were seen in children with UTI. Analysis of variance (ANNOVA) did not reveal significant differences in TLC between children with different diagnosis. In Group 2, majority of the etiology was lower respiratory tract infection/inflammation and short febrile illness.Conclusions: SBI comprise only half of the febrile children with leukocytosis. The predictive accuracy of leukocytosis in diagnosing SBI is poor. Vomiting and seizures probably incite stress mediated leukocytosis and are commonly encountered in febrile child with a high TLC without SBI. Further models with addition of clinical data and other surrogates of infection need to be developed to improve prediction of SBI in a febrile child.  

scholarly journals Investigation of hematological and biochemical profiles of anestrous zebu cows

2014 ◽  
Vol 11 (1) ◽  
pp. 57-60
Author(s):  
KF Pariza ◽  
J Alam ◽  
MR Islam ◽  
MM Hossain ◽  
MA Awal
Keyword(s):  
Biochemical Marker ◽  
Leukocyte Count ◽  
Total Leukocyte Count ◽  
Control Group ◽  
Bilirubin Concentration ◽  
Humoral Immune ◽  
Biochemical Profiles ◽  
The Mean ◽  
Status Analysis ◽  
Zebu Cows

Blood samples from cows with anestrous were collected for hematological, biochemical and humoral immune status analysis. The erythrocyte sedimentation rate (ESR) was higher and hemoglobin (Hb %) percentage was lower in anestrous group of cows than that of normal cycling control group of cows. The packed cell volume (PCV %) was lower in anestrous group of cows compared with the control group of cows. Total erythrocyte count was not significantly different between two groups of cows. The total leukocyte count was significantly higher in anestrous group of cows than that of control counterpart. The bilirubin concentration was significantly higher in anestrous group of cows compared with the control group of cows. The mean serum immunoglobulin (IgG) was lower in anestrous group of cows than that of control group of cows. It is suggested that there is no specific hematological and biochemical marker for anestrous in zebu cows.DOI: http://dx.doi.org/10.3329/bjvm.v11i1.13023Bangl. J. Vet. Med. (2013). 11 (1): 57-60

scholarly journals Clinico-pathological profiles of sub-fertility in Zebu Cows

1970 ◽  
Vol 26 (1) ◽  
pp. 1-7
Author(s):  
KF Pariza ◽  
ASM Bari ◽  
FY Bari ◽  
MGS Alam ◽  
M Noor
Keyword(s):  
Leukocyte Count ◽  
Total Leukocyte Count ◽  
Reproductive Disorders ◽  
Bilirubin Concentration ◽  
Uterine Infection ◽  
Humoral Immune ◽  
Erythrocyte Sedimentation ◽  
The Mean ◽  
Repeat Breeder ◽  
Zebu Cows

Blood samples from cows with reproductive problems (anoestrus, repeat breeder, uterine infection) were collected for haematological, biochemical and humoral immune response analyses. The erythrocyte sedimentation rate (ESR) was higher and haemoglobin (Hb) lowers in subfertile cows than innormal cycling cows. The packed cell volume (PCV) was lower in anoestrus and repeat breeding cows than in control. Total erythrocyte count (TEC) was not significantly different, whereas total leukocyte count (TLC) significantly higher (p<0.01) in anoestrus and repeat breeder cows. The bilirubin concentration was significantly higher (p<0.005) in anoestrus and uterine infected cows compared with control. The mean serum IgG was lower in all subfertile cows than control. It is suggested that there is no specific clinico-pathological marker for reproductive disorders in cows. DOI: 10.3329/bvet.v26i1.4624 Bangl. vet. 2009. Vol. 26, No. 1, 1-7

scholarly journals Immune function during pregnancy varies between ecologically distinct populations

2020 ◽  
Vol 2020 (1) ◽  
pp. 114-128
Author(s):  
Carmen Hové ◽  
Benjamin C Trumble ◽  
Amy S Anderson ◽  
Jonathan Stieglitz ◽  
Hillard Kaplan ◽  
...  
Keyword(s):  
Leukocyte Count ◽  
Total Leukocyte Count ◽  
Future Research ◽  
Differential Leukocyte Count ◽  
Ecological Conditions ◽  
Trade Offs ◽  
The Usa ◽  
Immunological Changes ◽  
Fetal Antigens ◽  
Pathogen Exposure

Abstract Background and objectives Among placental mammals, females undergo immunological shifts during pregnancy to accommodate the fetus (i.e. fetal tolerance). Fetal tolerance has primarily been characterized within post-industrial populations experiencing evolutionarily novel conditions (e.g. reduced pathogen exposure), which may shape maternal response to fetal antigens. This study investigates how ecological conditions affect maternal immune status during pregnancy by comparing the direction and magnitude of immunological changes associated with each trimester among the Tsimane (a subsistence population subjected to high pathogen load) and women in the USA. Methodology Data from the Tsimane Health and Life History Project (N = 935) and the National Health and Nutrition Examination Survey (N = 1395) were used to estimate population-specific effects of trimester on differential leukocyte count and C-reactive protein (CRP), a marker of systemic inflammation. Results In both populations, pregnancy was associated with increased neutrophil prevalence, reduced lymphocyte and eosinophil count and elevated CRP. Compared to their US counterparts, pregnant Tsimane women exhibited elevated lymphocyte and eosinophil counts, fewer neutrophils and monocytes and lower CRP. Total leukocyte count remained high and unchanged among pregnant Tsimane women while pregnant US women exhibited substantially elevated counts, resulting in overlapping leukocyte prevalence among all third-trimester individuals. Conclusions and implications Our findings indicate that ecological conditions shape non-pregnant immune baselines and the magnitude of immunological shifts during pregnancy via developmental constraints and current trade-offs. Future research should investigate how such flexibility impacts maternal health and disease susceptibility, particularly the degree to which chronic pathogen exposure might dampen inflammatory response to fetal antigens. Lay Summary This study compares immunological changes associated with pregnancy between the Tsimane (an Amazonian subsistence population) and individuals in the USA. Results suggest that while pregnancy enhances non-specific defenses and dampens both antigen-specific immunity and parasite/allergy response, ecological conditions strongly influence immune baselines and the magnitude of shifts during gestation.

scholarly journals Hematological Profile of HIV-Infected Patients on First-Line Highly Active Antiretroviral Therapy and Its Correlation With CD4 Count

2021 ◽  
Author(s):  
John Jospeh Diamond Princy ◽  
Kshetrimayum Birendra Singh ◽  
Ningthoujam Biplab ◽  
Ningthoukhongjam Reema ◽  
Rajesh Boini ◽  
...  
Keyword(s):  
Platelet Count ◽  
Antiretroviral Therapy ◽  
Hiv Infection ◽  
Highly Active Antiretroviral Therapy ◽  
Cd4 Count ◽  
Total Leukocyte Count ◽  
Hiv Patients ◽  
Positive Correlation ◽  
Highly Active ◽  
The Mean

Abstract Introduction Human immunodeficiency virus (HIV) infection is a state of profound immunodeficiency. Disorders of hematopoietic system are a common but often overlooked complication of HIV infection. This can manifest at any stage of the disease but more commonly in the advanced stage with low CD4 count. Anemia is the most common hematological abnormality in HIV patients and prevalence ranges from 1.3 to 95%. As HIV disease progresses, the prevalence and severity of anemia also increase. Hence, this study was undertaken to assess the hematological parameters of HIV-infected patients on highly active antiretroviral therapy (HAART) at different treatment durations with the hope to improve the HAART outcome in HIV patients and its correlation with CD4 count. Methods This prospective longitudinal study enrolled 134 HIV-infected patients admitted to or attending the OPD in the Department of Medicine or Antiretroviral Therapy (ART) Center (Center of Excellence), Regional Institute of Medical Sciences (RIMS), Imphal, Manipur, from 2018 to 2020. Complete hemogram, CD4 count, and other related-blood investigations were studied. Results The mean age of the study population was 39.9 ± 11.04 years. Of the 134 patients, 75 (56%) were males and 59 (44%) were females. Twelve (9%) patients had a history of injecting drug use (IDU). TLE (tenofovir, lamivudine, efavirenz) regimen was started on 112 (83.6%) patients and the majority of them (69/134 [51.5%]) had a CD4 count of 200 to 499 cells/mm3, which increased significantly 6 months after HAART to 99 to 1,149 cells/mm3, with a mean of 445 ± 217 cells/mm3. There were significant improvements in hemoglobin (Hb) levels, total leukocyte count (TLC), absolute neutrophil count (ANC), and absolute lymphocyte count (ALC) after HAART indicating a positive correlation with CD4 count (p < 0.05). Thrombocytopenia was observed higher after HAART when compared to baseline. There was a positive correlation between platelet count and CD4 count. However, the mean corpuscular volume (MCV) and erythrocyte sedimentation rate (ESR) had a negative correlation with CD4 count. Conclusion The study inferred a strong positive correlation between CD4 and Hb levels, TLC, ANC, ALC, and platelet count after HAART with improvement in these values as CD4 count increases. Specific treatment intervention based on the changes in the immunohematological profile trends can help prevent most of the adverse effects on HIV patients in our community.

scholarly journals AB0287 HEMATOLOGICAL SIDE EFFECTS OF BIOLOGICAL THERAPY IN RHEUMATOLOGY: DATA FROM THE TUNISIAN REGISTER

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1442.2-1442
Author(s):  
H. Bettaieb ◽  
S. Boussaid ◽  
S. Jemmali ◽  
S. Rekik ◽  
E. Cheour ◽  
...  
Keyword(s):  
Side Effects ◽  
Biological Treatment ◽  
Blood Count ◽  
Biological Therapy ◽  
National Registry ◽  
Close Monitoring ◽  
Female Ratio ◽  
Therapy Initiation ◽  
Male Female Ratio ◽  
The Mean

Background:During the last decade, the treatment of chronic inflammatory rheumatism (CIR) has been greatly improved with the advent of biotherapy.However, the use of biological treatment can lead to a number of side effects including abnormalities in the blood count.Objectives:The aim of this study was to assess the different hematological side effects of biological treatment in patients with rheumatoid arthritis (RA) and spondyloarthitis (SA).Methods:This study included patients with RA (ACR/EULAR 2010) and SA (ASAS 2009) registred with the Tunisian Biologic National Registry (BINAR).Patients were followed and treated with biologics for 2 years of less. Clinical data relative to biological treatment, including haematological side effects, have been collected.Results:Two hundred and ninety-eight patients (178 women and 111 men) were included in the study.The mean age was 49.2 ± 14.1 years. The male/female ratio was 0.6. The mean diseases durations for RA and SA were respectively 6.7 ± 3.5 years and 6.5 ±3.6 years.Anti-TNFα agents were prescribed in 87.9% of patients (n = 263) with respectively: Infliximab (20.4%) Etanercept (23.1%), Adalimumab (24.6%) and Certolizumab (26.5%).Tocilizumab and Rituximab were prescribed in 10.4% and 5% of the patients, respectively.Blood count abnormalities were noted in 15.4 % of patients (n=46).Neutropenia was the most frequently anomaly met on the hemogram (9.1%) followed by anemia (3.4%) and thrombocytopenia (3%). Pancytopenia was found in 11.4% of patients (n=34).The median time between biological therapy initiation and the onset of hematologic manifestations was 4.8 months [1-12]. Biological treatment was interrupted in two patients.In the other cases, the biological treatment was maintained with close monitoring of blood cell count. No case of death related to these hematological disturbances has been reported.Conclusion:In our registry, hematological side effects of biological treatment were found in 15.4% of cases and were noted with a median delay of 4.8 [1-12] months after the treatment initiation. Further studies are needed to confirm our preliminary results.Disclosure of Interests:None declared

scholarly journals The mongolian gerbil: qualitative and quantitative aspects of the cellular blood picture

1975 ◽  
Vol 9 (4) ◽  
pp. 283-287 ◽  
Author(s):  
Walter G. Dillon ◽  
Chester A. Glomski
Keyword(s):  
Haemoglobin Level ◽  
Cell Volume ◽  
Mongolian Gerbil ◽  
Leukocyte Count ◽  
Absolute Number ◽  
Total Leukocyte Count ◽  
Red Cell ◽  
Blood Picture ◽  
Qualitative And Quantitative ◽  
Circulating Lymphocytes

The gerbil displays sex determined differences in packed red-cell volume, haemoglobin level, total leukocyte count and absolute number of circulating lymphocytes. The erythrocytes demonstrate a prominent polychromasia and frequent occurrence of basophilic stippling.

Outcomes of Peripheral Blood Eosinophilia in Hospitalized Exacerbations of COPD

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Samar El Sharkawy ◽  
Riham Hazem Raafat ◽  
Reem Osama Mohamed Ahmed Qassem
Keyword(s):  
Peripheral Blood ◽  
Diagnostic Performance ◽  
Leukocyte Count ◽  
Airflow Limitation ◽  
Total Leukocyte Count ◽  
Blood Eosinophil ◽  
Copd Exacerbation ◽  
Peripheral Blood Eosinophil ◽  
Copd Exacerbations ◽  
Cutoff Points

Abstract Background The Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines define COPD as a disease state characterized by airflow limitation that is not fully reversible, is usually progressive, and is associated with an abnormal inflammatory response of the lungs to inhaled noxious particles or gases. Objective To identify outcomes of patients with eosinophilic COPD exacerbations requiring hospital admission. Patients and Methods This study is a prospective cohort study that was conducted on two groups of total 60 patients recruited from Ain Shams University hospitals between October 2019 and July 2020. Group 1: Eosinophilic COPD exacerbation if the peripheral blood eosinophil on admission is ≥ 200 cells/µL and/or ≥2% of the total leukocyte count Group 2: Non-eosinophilic COPD exacerbation if the peripheral blood eosinophil on admission is &lt; 200 cells/µL and/or &lt; 2% of the total leukocyte count. Results There was significant high diagnostic performance in predicting readmission at 6-month among eosinophilic group. Eosinophils count, percent (%) and NLR cutoff points had high characteristics (highest in NLR ≥3.1 at discharge) in predicting readmission at 6-month among eosinophilic group. Diagnostic performance of Eosinophils count, percent (%) and NLR were assessed. Eosinophils count, percent (%) and NLR had significant high diagnostic performance in predicting readmission at 6-month among eosinophilic group. Eosinophils count, % and NLR cutoff points had high characteristics (highest in NLR ≥2.1 at discharge) in predicting readmission at 6month among non-eosinophilic group. Conclusion Eosinophils can be used as a prognostic marker in non-infective COPD exacerbations. Validity of eosinophil count and percent as a prognostic parameter in COPD exacerbation can be increased by combining with other parameters for example NLR.

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