scholarly journals Parametric model of the structure of the second molar of a human lower jaw

Author(s):  
Anna Genrikhovna Yanishevskaya ◽  
Zhanna Vladimirovna Golikova ◽  
Fedor Nikolaevich Pritykin ◽  
Vasilii Gerasimovich Khomchenko

In this paper the design of a parametric tooth model is considered, with the help of which it is possible to study the development of dental pathology. This model allows you to create a tooth prosthesis, with minimal intervention of the dentist, by creating a three-dimensional image of the studied tooth, close in architecture to the real one. Particular attention is paid to the study of the geometry of the tooth - the second molar. Based on the analysis of the presented initial data, additional characteristics were introduced, due to which the geometry of the surface areas of the tooth model is calculated. The article discusses the advantages and disadvantages of visualization methods used in this area to solve problems associated with the analysis of complex and heterogeneous information, and also presents conclusions on practical and scientific results. A parametric model of a tooth was built, which describes its geometry in comparative detail. The main necessary parameters and their limitations are determined. The obtained calculations of the geometric shape of the tooth can be used to study and analyze the biomechanics of teeth, the principles of differential diagnosis of pain, planning future iatrogenic intervention, as well as algorithms for the treatment of prosthetic disorders, provides the doctor with all the necessary tools. The constructed crown part of the tooth in the AutoCAD system can be used for teaching dental students. This model can be used for scientific and practical activities of students on the modeling and restoration of dental crowns.

2008 ◽  
Vol 78 (3) ◽  
pp. 502-509 ◽  
Author(s):  
Carmen Gonzales ◽  
Hitoshi Hotokezaka ◽  
Masako Yoshimatsu ◽  
Joseph H. Yozgatian ◽  
M. Ali Darendeliler ◽  
...  

Abstract Objective: To test the hypothesis that there is no difference in the effect of different continuous moderate to very heavy forces on root resorption or amount of tooth movement. Materials and Methods: In the study, 10, 25, 50 and 100 g mesial force were applied to the maxillary first molars of rat using nickel titanium closed-coil springs for 3 days, 14 days, and 28 days. The molars were extracted and the surface areas of the root resorption craters were measured using scanning electron microscope. The depths of the root resorption craters were measured using a three-dimensional laser scanning microscope. Tooth movement of the maxillary first molar was measured in relation to the maxillary second molar on digitized lateral cephalometric radiographs. Results: Three days after force application, the tooth movement was not proportionally related to force magnitude. However, 14 days of force application resulted in significantly more tooth movement in the 10, 25, and 50 g force groups than in the 100 g force group. A force application of 10 g produced significantly more tooth movement at 28 days than all the other three force applications. The largest and deepest resorption craters were observed in the disto-buccal root followed by disto-palatal, middle-buccal, middle-palatal, and mesial root. Root resorption and tooth movement increased over time from 3 to 28 days. As heavier forces were applied, greater root resorption occurred. Conclusion: The hypothesis is rejected. The light mesially oriented forces, as applied in this study, produced more tooth movement and less root resorption compared with heavier forces.


2019 ◽  
Vol 952 (10) ◽  
pp. 47-54
Author(s):  
A.V. Komissarov ◽  
A.V. Remizov ◽  
M.M. Shlyakhova ◽  
K.K. Yambaev

The authors consider hand-held laser scanners, as a new photogrammetric tool for obtaining three-dimensional models of objects. The principle of their work and the newest optical systems based on various sensors measuring the depth of space are described in detail. The method of simultaneous navigation and mapping (SLAM) used for combining single scans into point cloud is outlined. The formulated tasks and methods for performing studies of the DotProduct (USA) hand-held laser scanner DPI?8X based on a test site survey are presented. The accuracy requirements for determining the coordinates of polygon points are given. The essence of the performed experimental research of the DPI?8X scanner is described, including scanning of a test object at various scanner distances, shooting a test polygon from various scanner positions and building point cloud, repeatedly shooting the same area of the polygon to check the stability of the scanner. The data on the assessment of accuracy and analysis of research results are given. Fields of applying hand-held laser scanners, their advantages and disadvantages are identified.


2021 ◽  
Vol 50 (2) ◽  
pp. 223-237 ◽  
Author(s):  
Hannes Witt ◽  
Filip Savić ◽  
Sarah Verbeek ◽  
Jörn Dietz ◽  
Gesa Tarantola ◽  
...  

AbstractMembrane-coated colloidal probes combine the benefits of solid-supported membranes with a more complex three-dimensional geometry. This combination makes them a powerful model system that enables the visualization of dynamic biological processes with high throughput and minimal reliance on fluorescent labels. Here, we want to review recent applications of colloidal probes for the study of membrane fusion. After discussing the advantages and disadvantages of some classical vesicle-based fusion assays, we introduce an assay using optical detection of fusion between membrane-coated glass microspheres in a quasi two-dimensional assembly. Then, we discuss free energy considerations of membrane fusion between supported bilayers, and show how colloidal probes can be combined with atomic force microscopy or optical tweezers to access the fusion process with even greater detail.


i-com ◽  
2020 ◽  
Vol 19 (2) ◽  
pp. 67-85
Author(s):  
Matthias Weise ◽  
Raphael Zender ◽  
Ulrike Lucke

AbstractThe selection and manipulation of objects in Virtual Reality face application developers with a substantial challenge as they need to ensure a seamless interaction in three-dimensional space. Assessing the advantages and disadvantages of selection and manipulation techniques in specific scenarios and regarding usability and user experience is a mandatory task to find suitable forms of interaction. In this article, we take a look at the most common issues arising in the interaction with objects in VR. We present a taxonomy allowing the classification of techniques regarding multiple dimensions. The issues are then associated with these dimensions. Furthermore, we analyze the results of a study comparing multiple selection techniques and present a tool allowing developers of VR applications to search for appropriate selection and manipulation techniques and to get scenario dependent suggestions based on the data of the executed study.


Pharmaceutics ◽  
2021 ◽  
Vol 13 (3) ◽  
pp. 358 ◽  
Author(s):  
Chiara R. M. Brambilla ◽  
Ogochukwu Lilian Okafor-Muo ◽  
Hany Hassanin ◽  
Amr ElShaer

Three-dimensional (3D) printing is a recent technology, which gives the possibility to manufacture personalised dosage forms and it has a broad range of applications. One of the most developed, it is the manufacture of oral solid dosage and the four 3DP techniques which have been more used for their manufacture are FDM, inkjet 3DP, SLA and SLS. This systematic review is carried out to statistically analyze the current 3DP techniques employed in manufacturing oral solid formulations and assess the recent trends of this new technology. The work has been organised into four steps, (1) screening of the articles, definition of the inclusion and exclusion criteria and classification of the articles in the two main groups (included/excluded); (2) quantification and characterisation of the included articles; (3) evaluation of the validity of data and data extraction process; (4) data analysis, discussion, and conclusion to define which technique offers the best properties to be applied in the manufacture of oral solid formulations. It has been observed that with SLS 3DP technique, all the characterisation tests required by the BP (drug content, drug dissolution profile, hardness, friability, disintegration time and uniformity of weight) have been performed in the majority of articles, except for the friability test. However, it is not possible to define which of the four 3DP techniques is the most suitable for the manufacture of oral solid formulations, because the selection is affected by different parameters, such as the type of formulation, the physical-mechanical properties to achieve. Moreover, each technique has its specific advantages and disadvantages, such as for FDM the biggest challenge is the degradation of the drug, due to high printing temperature process or for SLA is the toxicity of the carcinogenic risk of the photopolymerising material.


Author(s):  
Shengli Dai ◽  
Weimin Zhang ◽  
Jiamin Zong ◽  
Yingying Wang ◽  
Ge Wang

Although many countries around the world, especially China, highlight the strategy of green development, there has been little research evaluating the effectiveness of green development policies in local area. This study explores 16 policy texts with the theme of green development in the Yangtze River Economic Belt in China. Using the Policy Modeling Consistency Index (PMC-Index) model, the paper establishes a multi-input–output policy table and scientifically and systematically evaluates these policies. The results show that the average PMC index of the 16 policy texts is 6.83, indicating a high overall quality of policy texts. The index identifies two states of policy effectiveness as being good and excellent; 50% of the total texts fall into these categories and do not fall into the category of having a low level of policy effectiveness. Five indicators, including policy timeliness, social benefits, policy audience scope, and incentives and constraints, significantly impact the PMC-Index of the policy. Six representative policy samples were selected and analyzed. The advantages and disadvantages of the policy can be more fully understood by the degree of depression of the PMC’s three-dimensional curved surface (PMC-Surface) model. Finally, the paper provides theoretical recommendations for the optimization of the green development policies.


2007 ◽  
Vol 44 (3) ◽  
pp. 278-285 ◽  
Author(s):  
Virgilio F. Ferrario ◽  
Fabrizio Mian ◽  
Redento Peretta ◽  
Riccardo Rosati ◽  
Chiarella Sforza

Objective: To compare three-dimensional nasal measurements directly made on subjects to those made on plaster casts, and nasal dimensions obtained with a surface-based approach to values obtained with a landmark representation. Methods: Soft-tissue nasal landmarks were directly digitized on 20 healthy adults. Stone casts of their noses were digitized and mathematically reconstructed using nonuniform rational B-splines (NURBS) curves. Linear distances, angles, volumes and surface areas were computed using facial landmarks and NURBS-reconstructed models (surface-based approach). Results: Measurements on the stone casts were somewhat smaller than values obtained directly from subjects (differences between −0.05 and −1.58 mm). Dahlberg's statistic ranged between 0.73 and 1.47 mm. Significant (p < .05) t values were found for 4 of 15 measurements. The surface-based approach gave values 3.5 (volumes) and 2.1 (surface area) times larger than those computed with the landmark-based method. The two values were significantly related (volume, r = 0.881; surface, r = 0.924; p < .001), the resulting equations estimated actual values well (mean difference, volume −0.01 mm3, SD 1.47, area 0.05 cm2, SD 1.44); limits of agreement between −2.89 and 2.87 mm3 (volume); −2.88 and 2.78 cm2 (area). Conclusions: Considering the characteristics of the two methods, and for practical purposes, nasal distances and angles obtained on plaster models were comparable to digital data obtained directly from subjects. Surface areas and volumes were best obtained using a surface-based approach, but could be estimated using data provided by the landmark representation.


Author(s):  
Khaled E. Zaazaa ◽  
Brian Whitten ◽  
Brian Marquis ◽  
Erik Curtis ◽  
Magdy El-Sibaie ◽  
...  

Accurate prediction of railroad vehicle performance requires detailed formulations of wheel-rail contact models. In the past, most dynamic simulation tools used an offline wheel-rail contact element based on look-up tables that are used by the main simulation solver. Nowadays, the use of an online nonlinear three-dimensional wheel-rail contact element is necessary in order to accurately predict the dynamic performance of high speed trains. Recently, the Federal Railroad Administration, Office of Research and Development has sponsored a project to develop a general multibody simulation code that uses an online nonlinear three-dimensional wheel-rail contact element to predict the contact forces between wheel and rail. In this paper, several nonlinear wheel-rail contact formulations are presented, each using the online three-dimensional approach. The methods presented are divided into two contact approaches. In the first Constraint Approach, the wheel is assumed to remain in contact with the rail. In this approach, the normal contact forces are determined by using the technique of Lagrange multipliers. In the second Elastic Approach, wheel/rail separation and penetration are allowed, and the normal contact forces are determined by using Hertz’s Theory. The advantages and disadvantages of each method are presented in this paper. In addition, this paper discusses future developments and improvements for the multibody system code. Some of these improvements are currently being implemented by the University of Illinois at Chicago (UIC). In the accompanying “Part 2” and “Part 3” to this paper, numerical examples are presented in order to demonstrate the results obtained from this research.


2016 ◽  
Vol 19 (1) ◽  
pp. 101-114 ◽  
Author(s):  
Eman Gadalla ◽  
Ibrahim Abosag ◽  
Kathy Keeling

Purpose – This study aims to examine the nature and the potential use of avatar-based focus groups (AFGs) (i.e. focus groups conducted in three-dimensional [3D] virtual worlds [VWs]) as compared to face-to-face and online focus groups (OFGs), motivated by the ability of VWs to stimulate the realism of physical places. Over the past decade, there has been a rapid increase in using 3D VWs as a research tool. Design/methodology/approach – Using a two-phase reflective approach, data were collected first by using traditional face-to-face focus groups, followed by AFGs. In Phase 2, an online, semi-structured survey provided comparison data and experiences in AFGs, two-dimensional OFGs and traditional face-to-face focus groups. Findings – The findings identify the advantages and disadvantages of AFGs for marketing research. There is no evident difference in data quality between the results of AFGs and face-to-face focus groups. AFG compensates for some of the serious limitations associated with OFGs. Practical implications – The paper reflects on three issues, data quality, conduct of AFGs (including the moderator reflection) and participant experience, that together inform one’s understanding of the characteristics, advantages and limitations of AFG. Originality/value – This is the first paper to compare between AFGs, traditional face-to-face focus groups and OFGs. AFG holds many advantages over OFGs and even, sometimes, over face-to-face focus groups, providing a suitable environment for researchers to collect data.


Marine Drugs ◽  
2021 ◽  
Vol 19 (6) ◽  
pp. 311
Author(s):  
Yang Li ◽  
Wang Li ◽  
Zhengshuang Xu

Peptides have a three-dimensional configuration that can adopt particular conformations for binding to proteins, which are well suited to interact with larger contact surface areas on target proteins. However, low cell permeability is a major challenge in the development of peptide-related drugs. In recent years, backbone N-methylation has been a useful tool for manipulating the permeability of cyclic peptides/peptidomimetics. Backbone N-methylation permits the adjustment of molecule’s conformational space. Several pathways are involved in the drug absorption pathway; the relative importance of each N-methylation to total permeation is likely to differ with intrinsic properties of cyclic peptide/peptidomimetic. Recent studies on the permeability of cyclic peptides/peptidomimetics using the backbone N-methylation strategy and synthetic methodologies will be presented in this review.


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