scholarly journals Acetaminophen Serum Levels in Patients with unknown Poisoning and Loss of Consciousness

2019 ◽  
Vol 7 (2) ◽  
pp. 20
Author(s):  
Alireza Ala ◽  
Samad Shams Vahdati ◽  
Ghader Bakhsh Rigi ◽  
Paria Habibollahi ◽  
Shahrad Tajodini ◽  
...  
Keyword(s):  
Analytical Study ◽  
Serum Levels ◽  
Loss Of Consciousness ◽  
Toxic Level ◽  
Mortality And Morbidity ◽  
Level Of Consciousness ◽  
Minimum Age ◽  
History Of ◽  
The Mean ◽  
Outcome Mortality

Background: The aim of this study was to evaluate the serum levels of acetaminophen in patients with unknown poisoning and loss of consciousness, and to assess whether measuring serum acetaminophen level in all patients with drug overdose or decreased level of consciousness changes outcome. Methods & Materials: In a descriptive-analytical study, 300 patients with loss of consciousness and a history of drug toxicity with an unknown drug that referred to the emergency unit constituted the study sample. Serum acetaminophen levels of patients, the outcome, mortality, and morbidity of patients were evaluated. Results: The mean age of patients was 28.88±8.67 years. The minimum age of patients was 15 years and the maximum age of patients was 58 years. The mean serum level of acetaminophen in patients was 0.62±0.55 μg/ml. The highest level and the lowest level of acetaminophen in patients were 2.8 μg/ml and 0.2 μg/ml respectively. Serum acetaminophen level in patients was less than the toxic level (less than 30 μg/ml). Conclusion: Based on the findings of this study, acetaminophen as a widely used and available drug is not a common cause of poisoning in patients with loss of consciousness in our region.

Evaluation of Analgesic and Sedative Effects of Ketamine Infusion against Intravenous Morphine in Relieving Fracture Pain of Long or Short Bones of Upper and Lower Limbs

2021 ◽  
Vol 15 (6) ◽  
pp. 1807-1811
Author(s):  
Meysam Moezi ◽  
Hassan Motamed ◽  
Mohammad Ali Fahimi ◽  
Azam Khalighi
Keyword(s):  
Emergency Department ◽  
Lower Limbs ◽  
Ketamine Infusion ◽  
Disturbed Sleep ◽  
Limb Trauma ◽  
Level Of Consciousness ◽  
Sedative Effects ◽  
Intravenous Morphine ◽  
Minimum Age ◽  
The Mean

Introduction and Purpose: The importance of pain control in patients with limb trauma in the emergency department and its complications is the main issue in post-emergency care and plays an important role in accelerating the improvement of patients' general status. Therefore, the present study aimed to evaluate the analgesic and sedative effects of ketamine infusion against intravenous morphine in relieving fracture pain of long or short bones in the upper and lower limbs. Materials and Methods: We examined the effect of ketamine and morphine as ketamine infusion at a dose of 0.4 mg/kg/IV/10min and intravenous morphine at a dose of 0.1 mg/kg/IV in patients aged 18-65 years with limb trauma who visited the hospital emergency department. We also compared the duration of analgesia, the amount of pain relief according to the Visual Analogue Scale (VAS) in each of the drugs and complications of the above methods, including apnea, bradycardia, tachycardia, decreased level of consciousness, nausea, vomiting, hypertension and hypotension, seizures, and disturbed sleep, and mentioned the preferred method. Results: In the study, we studied 120 patients, 60 of whom received ketamine and 60 received morphine. The mean age of patients was 13.02±13.67 years with a minimum age of 19 years and a maximum age of 70 years, and 89(74.2%) patients were male. There was not any difference between ketamine and morphine in the factors at different times. Conclusion: The results indicated that the potency of low-dose ketamine in relieving pain in patients was very similar to morphine. Keywords: Bone fracture; Ketamine; Morphine.

scholarly journals Prevalence of Trigeminal Neuralgia in Patients with Chronic Facial Pain in Neurology Lrh Hospital Peshawar.

2021 ◽  
Vol 6 (6) ◽  
pp. 1-7
Author(s):  
Saad Ali ◽  
Zahwa Salam ◽  
Shakir Ullah ◽  
Mehtab Alam ◽  
Harwindar Kumar
Keyword(s):  
Trigeminal Neuralgia ◽  
Facial Pain ◽  
Tooth Extraction ◽  
Age Group ◽  
Cross Sectional ◽  
Maxillary Nerve ◽  
Minimum Age ◽  
History Of ◽  
The Mean ◽  
Hospital Study

Background: Trigeminal Neuralgia (TN) consist of brief periodic but severe and chronic facial pain in acial region in single or multiple branches of the trigeminal nerve. Objective: The objective of this study was to find the prevalence of TN in patients with chronic facial pain. Methodology: This cross sectional observational study was conducted at Department of Neurology OPD Lady Reading Hospital, Peshawar. 46 patients with chronic facial pain were selected for the study. All data was taken on a structured Performa and was entered and analyzed using SPSS version 21. Using non probability consecutive sampling after taking approval from Ethical Committee of the hospital, study duration was 10 months from 25-1-2019 to 25-10-2019. Results: Out of 46 patients, there were 18 (39.1%) males and 28 (60.9%) females. The mean age of the patients was 50.67, the Standard Deviation recorded was 11.56. Minimum age was 21 and maximum age was 67. 23. Out of 31 patients diagnosed with TN had history of tooth extraction and 8 had no extraction. Out of 31 patients presented with TN, right side was involved in 24 (52.2%) patients and left side was involved in 7 (15.2%) patients. Mandibular never was more common in the patients with TN which was 37% followed by maxillary nerve 21.7%, and ophthalmic nerve at 8.7%. Majority of the patients 28 (75.7%) belonged to the age group of 40 to 67. Females having TGN were 78% and males were 50%. Right side (52.2%) was more involved than left side. Mandibular division (37%) was more involved than maxillary and ophthalmic division. Conclusion: We conclude that females are more at risk of developing TN than males. Increasing age has a higher chance of developing TN. Right side is more involved than left. Mandibular division is more involved than maxillary and ophthalmic.

scholarly journals Congenital malformations among newborns in Morocco: A retrospective study

2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Adil Elghanmi ◽  
Rachid Razine ◽  
Mohamed Jou ◽  
Rachid Berrada
Keyword(s):  
Retrospective Study ◽  
Congenital Malformations ◽  
Chromosomal Abnormalities ◽  
Maternal Body Mass Index ◽  
Mortality And Morbidity ◽  
Tertiary Teaching ◽  
History Of ◽  
Tertiary Teaching Hospital ◽  
The Mean ◽  
Neonates And Infants

Congenital malformations are one of the leading causes of neonates and infants’ mortality and morbidity. The frequency of these congenital malformations varies in different populations. The objective of this study was to find out the prevalence and pattern of congenital malformations in a tertiary teaching hospital in Rabat, Morocco. This four-year retrospective descriptive study was conducted from January 2011 to December 2014. All newborns with congenital malformations diagnosed at birth were included. Mothers and newborn characteristics were analyzed using SPSS 13.0. A total of 706 newborns were noted to have congenital malformation. The prevalence rate was 1.02%. The mean maternal age was 28.8±7.2 years. The mean maternal body mass index was 28.1±6.9 kg/m2. 13.3% of the mothers had a history of abortion. The nervous system was the most affected system (19.4%) followed by the musculoskeletal system (14.2%), the chromosomal abnormalities (12.3%) and the genito-urinary system (10.8%). Males newborns (57.9%) had more congenital malformations than females (40.5%). The rates for live-births, fetal asphyxia and stillbirths were 75.2%, 7.2% and 17.3%, respectively. This retrospective study provides recent and detailed data about congenital malformations in a Moroccan region. The result from this study will contribute to the knowledge of congenital malformations in this particular area and hence the supportive preventive policy.

The effects of intravenous aminophylline on level of consciousness in acute intentional benzodiazepines poisoning in comparison to flumazenil

2016 ◽  
Vol 36 (3) ◽  
pp. 311-316
Author(s):  
A Aghabiklooei ◽  
J Sangsefidi
Keyword(s):  
Lung Disease ◽  
Older Patients ◽  
Significant Loss ◽  
Controlled Study ◽  
Loss Of Consciousness ◽  
Mortality And Morbidity ◽  
Respiratory Effects ◽  
Positive Effects ◽  
Level Of Consciousness ◽  
Neonatal Apnea

Aim: Acute intentional benzodiazepine poisoning is marked by a significant loss of consciousness, aspiration pneumonia, and increased rates of mortality and morbidity, especially in older patients with underlying heart or lung disease. These patients may need flumazenil to reverse the respiratory effects of benzodiazepines. The positive effects of aminophylline on respiration and neonatal apnea improvement have been shown previously. However, its possible effects on increasing the level of consciousness have never been evaluated. Methods: In a placebo-controlled study, we assessed the effectiveness of aminophylline on increasing the level of consciousness. Results: Time to full awakening was significantly shorter in those who received aminophylline (72 min vs. 881 min, p = 0.001), compared to those who received a placebo. Conclusion: When “flumazenil” is contraindicated or unavailable, intravenous aminophylline can be used as a second choice.

scholarly journals Distances and ages of globular clusters

2007 ◽  
Vol 3 (S248) ◽  
pp. 440-442 ◽  
Author(s):  
B. Chaboyer
Keyword(s):  
Globular Clusters ◽  
Milky Way ◽  
Formation History ◽  
Minimum Age ◽  
History Of ◽  
The Mean ◽  
Age Of The Universe ◽  
The Universe ◽  
Age Determinations

AbstractAs the oldest objects whose ages can be accurately determined, Galactic globular clusters can be used to establish the minimum age of the universe (and hence, to constrain cosmological models) and to study the early formation history of the Milky Way. The largest uncertainty in the determination of globular cluster ages is the distance scale. The current uncertainty in the distances to globular clusters is ~ 6%, which leads to a 13% uncertainty in the absolute ages of globular clusters. I am the PI on a SIM-Planetquest key project to determine the distances of 21 globular clusters with an accuracy of ranging from 1 to 4%. This will lead to age determinations accurate to 5 − 9%. The mean age of the oldest, most metal-poor globular clusters will be determined with an accuracy of ±3%.

scholarly journals Relationships between Serum Levels of Atazanavir and Renal Toxicity or Lithiasis

2015 ◽  
Vol 2015 ◽  
pp. 1-7 ◽  
Author(s):  
C. I. Marinescu ◽  
M. Leyes ◽  
M. A. Ribas ◽  
M. Peñaranda ◽  
J. Murillas ◽  
...  
Keyword(s):  
Cumulative Incidence ◽  
Renal Colic ◽  
Renal Toxicity ◽  
Statistical Significance ◽  
Serum Levels ◽  
Urine Ph ◽  
History Of ◽  
The Mean ◽  
Palma De Mallorca ◽  
The Relationship

The main aim of this study is to describe the relationship between serum levels of atazanavir, renal toxicity, and lithiasis. This is a prospective observational study of patients being treated with atazanavir (ATV) at Son Espases Teaching Hospital, Palma de Mallorca, between 2011 and 2013. The study includes 98 patients. Sixteen were found to have a history of urolithiasis. During a median monitoring period of 23 months, nine patients suffered renal colic, in three of whom ATV crystals were evidenced in urine. Cumulative incidence of renal colic was 9.2 per 100 patients. The variables related to having renal colic were the presence of alkaline urine pH and lower basal creatinine clearance. The mean serum level of ATV was slightly higher in patients with renal colic—1,303 μg/L versus 1,161 μg/L—but did not reach statistical significance. Neither were any significant differences detected by analysing the levels according to the timetable for ATV dosage. Cumulative incidence of renal colic was high in patients being treated with ATV, in 33% of whom the presence of ATV crystals was evidenced in urine. We were unable to demonstrate a relationship between ATV serum levels and renal colic or progression towards renal failure.

STUDY OF CARDIOVASCULAR RISK FACTORS DURING GESTATIONAL DIABETES IN SENEGAL

2021 ◽  
pp. 98-102
Author(s):  
Soumah I.Y ◽  
Thiam S ◽  
Toure Y ◽  
Ndiaye A ◽  
Samba A ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cardiovascular Risk ◽  
Gestational Diabetes ◽  
Analytical Study ◽  
Delayed Diagnosis ◽  
Favourable Outcome ◽  
Apo B ◽  
History Of ◽  
The Mean ◽  
Lipid Parameters

The evolution of gestational diabetes is most often marked by preventable maternal-foetal complications. The objective of this study was to identify factors inuencing the development of pregnancy in women with gestational diabetes. This was a retrospective and analytical study including women with gestational diabetes and treated in gynaecological services in Dakar and its suburbs between 2018 and 2019. A total of 24 women with gestational diabetes were recruited. The mean age of the patients was 29.9 ± 6.45 years (18-45) with a predominance of women over 30 years old. Dyslipidaemias were frequent (91.2%) with a predominance of hypercholesterolemia (n = 13, 54.2%) followed by hyperLDLemia (n = 10, 41.7%). The atherogenic risk was high with the TG / HDL (12.5%) and Apo B / A (20.83%) ratios. A positive correlation was noted between homocysteine and total cholesterol (r = 0.457, p = 0.025), LDL (r = 0.449, p = 0.028), triglycerides (r = 0.540, p = 0.006), apolipoproteins A (r = 0.463, p = 0.023) and B (r = 0.480, p = 0.018), urea (r = 0.0671, p <0.0001) and creatinine (r = 0.0673, p <0, 0001). The development of the pregnancy was marked by caesarean deliveries (54.2%) and macrosomia (8.3%). The factors which were identied in relation to the caesarean section were delayed diagnosis of GD, history of personal abortion (RR (CI) = 2.04 (0.4 - 10.6)), multiparity (RR (CI)) = 2.3 (0.4 - 12.7)) and the advanced age of the woman (RR (CI) = 2.1 (0.5 - 14.4)). The biological monitoring of women with gestational diabetes must consider the dosage of lipid parameters extended to apolipoproteins and homocysteine for a favourable outcome of the pregnancy

Attitude Examination Related to Breast Cancer Among Women in Bács-Kiskun County, Hungary

2016 ◽  
Vol 11 (3) ◽  
pp. 223-232
Author(s):  
Annamária Pakai ◽  
András Oláh ◽  
Gabriella Farkasné-Buzánczky ◽  
Mónika Sélleyné-Gyúró ◽  
Éva Brantmüller
Keyword(s):  
Breast Cancer ◽  
Health Status ◽  
Demographic Data ◽  
Principal Component ◽  
Its Region ◽  
Cross Sectional ◽  
Mortality And Morbidity ◽  
History Of ◽  
The Mean ◽  
Population Mortality

AbstractBreast cancer is the most commonly diagnosed type of cancer and a leading cause of mortality among women both in developed and developing countries all over the world. Our research questions were the following: 1. What is the ratio of women participating in mammography screening? 2. What factors influence the attendance of the screening? A quantitative, cross-sectional, and descriptive study (2013) examined women aged 35-65 without a history of breast cancer from Kecskemét City and its region. Non-random, convenience sampling method was applied in the study. The self-edited and self-administered questionnaire included the following groups of questions: socio-demographic data, attitude examination related to screening, reasons for absence. Besides SPSS Statistics, 20.00 test, x2 test, t-test, and ANOVA were used (p<0.05). During the Principal Component Analysis, 23 variables of the motivational scale were grouped into six theoretical subgroups, and the Cronbach-alpha value was 0.758. The mean age of the participants was 49.96±8.91 years.71% of the interviewees never attended breast cancer screening. Regarding the sample, the mean age of women participating in the screening for the first time was 39.66±12.21 years. Women with college/university degree attained high scores on the knowledge test (p<0.05). A significant part of women went to the screening because they feel responsibility for their health status or due to the family history of breast cancer. Fear, shame, or inconveniencies during examination did not affect participation in screening. Prevention programs play a significant role in the improvement of the health status of the Hungarian population. Mortality and morbidity indicators can be reduced by regularly organized, preventive activities based on appropriate knowledge. Thus, the number of healthy years can be increased.

scholarly journals Comparative Study of Salivary and Serum Levels of Vitamin D in Patients with a History of High Blood Pressure and Healthy People

2018 ◽  
Vol 8 (1) ◽  
pp. 101 ◽  
Author(s):  
Hamidreza Abdolsamadi ◽  
Mohammad vahedi ◽  
Farnaz Fariba ◽  
Alireza Soltanian ◽  
Meghdad Zakavati Avval ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Vitamin D ◽  
Serum Level ◽  
High Blood Pressure ◽  
Healthy Subjects ◽  
Serum Levels ◽  
Vitamin D Levels ◽  
Significant Difference ◽  
History Of ◽  
The Mean

Introduction: Vitamin D deficiency is a major public health problem. Low vitamin D levels associated with adverse health consequences such as musculoskeletal health, cognitive decline and progression of cancer and death. The lack of vitamin D associated with major risk factors for cardiovascular disease (CVD) includes hypertension is considered. The ability to assess the general health, disease and treatment outcomes through saliva as a non-invasive, inexpensive and simple method of interest is located. The aim of this study was a comparative study of salivary and serum levels of vitamin D3 in patients with a history of developing high blood pressure and a healthy person.Methods: This study was a case - control survey, in which 40 patients with high blood pressure were examined. The control group including 40 healthy subjects. Both groups were matched in terms of age and gender. After collecting samples of serum and saliva, the amount of vitamin D level samples were measured using ELISA method by electrochemiluminescence (ELC), and then analyzed the results using software SPSS 16 and statistical test including Chi Square Test, Independent-Samples, linear regression model, the Mann-Whitney Test and Spearman correlation coefficient.Results: There was no significant difference in the mean serum levels of vitamin D among patients and healthy subjects (p= 0.588). In addition, there was no significant difference in the mean salivary levels of vitamin D between patients and healthy subjects (p= 0.833). There was no significant relationship between salivary and serum level of vitamin D in healthy individuals (p= 0.095). As well as there was no significant correlation between salivary and serum level of vitamin D in patients (p= 0.5).Conclusions: This study showed that vitamin D is a measurable marker in saliva, but its analysis in saliva, may not be a reliable tool for determining the vitamin D levels.

scholarly journals Frequency of tramadol toxicity in Shahid Mohammadi Hospital in Bandar Abbas

2020 ◽  
Vol 9 (3) ◽  
pp. 130-133
Author(s):  
Amir Hasan Asadi ◽  
Yaser Khanchemehr ◽  
Atefeh Karimi Haji Khademi ◽  
Mehdi Lalehzari ◽  
Ahmad Haghiri Dehbarez
Keyword(s):  
Clinical Manifestations ◽  
Descriptive Study ◽  
Demographic Characteristics ◽  
Duration Of Hospital Stay ◽  
Level Of Consciousness ◽  
History Of ◽  
Synthetic Drug ◽  
The Mean ◽  
Spss Software ◽  
Bandar Abbas

Background: Tramadol is a synthetic drug with central mechanisms which binds to µ-opioid receptors. Recently, increased consumption and serious complications have been reported about this drug. Thus, the aim of this study was to determine the frequency of tramadol toxicity in Shahid Mohammadi Hospital in Bandar Abbas. Materials and Methods: This retrospective descriptive study was performed on individuals with tramadol toxicity admitted to Shahid Mohammadi Hospital, Bandar Abbas during 2013- 2014. Information was collected through patients’ medical files using a checklist including demographic characteristics, toxicity complications, and patients’ clinical outcomes. The acquired data were then analyzed using SPSS software. Results: The mean age of 53 patients was 24.71±7.76 years, of which 69.8% were males and 49.1% had a history of drug abuse. In addition, the seizure was observed in 49.1% of them, and 47.2% of cases simultaneously used another drug, along with tramadol. Further, the history of mental disorders was reported in 24.5% of patients. Clinical manifestations included a decreased level of consciousness (49.1%), nausea and/or vomiting (45.3%), and headache (30.2%). Furthermore, the duration of hospital stay was 48 hours in 90.6% of patients. Eventually, a significant correlation was found between seizure and drugs other than tramadol (P=0.001), gender (P=0.004), and occupation (P=0.010). Conclusion: Most cases of tramadol toxicity occur in students and young adults, resulting in complications such as seizure, decreased levels of consciousness, and nausea and/or vomiting. Accordingly, awareness of the complications of tramadol and meticulous observations over its methods of delivery could reduce the associated harms.

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