scholarly journals Molecular Detection of Human Papillomavirus (HPV) in Females and Assessment of Risk Factors for HPV Infection: A Study from Coastal Karnataka

2018 ◽  
Author(s):  
Varsha Saxena ◽  
Vidya Pai ◽  
K Rajagopal ◽  
Abdulla Mehnaz
Keyword(s):  
Risk Factors ◽  
Human Papillomavirus ◽  
Molecular Detection ◽  
Hpv Infection

The role of circumcision, tobacco, and alcohol use in genital human papillomavirus infection among men from Denmark

2021 ◽  
pp. 095646242110147
Author(s):  
Julie B Hebnes ◽  
Christian Munk ◽  
Kirsten Frederiksen ◽  
Hans O Joergensen ◽  
Thomas Iftner ◽  
...  
Keyword(s):  
Risk Factors ◽  
Sexual Behavior ◽  
Human Papillomavirus ◽  
Alcohol Use ◽  
Potential Risk ◽  
Hpv Infection ◽  
Sex Partners ◽  
Current Cigarette Smoking ◽  
Hpv Dna ◽  
Potential Risk Factors

It is crucial to understand the natural history of genital human papillomavirus (HPV) infection in men to prevent the increasing male HPV-related disease burden. We evaluated the associations between HPV infection and circumcision, smoking, and alcohol use after accounting for sexual behavior. The study included 2331 male personnel from Danish barracks. Penile swabs were tested for HPV DNA with a polymerase chain reaction assay, INNO-LiPA. All men completed a self-administered questionnaire providing data on potential risk factors for HPV such as lifestyle and sexual habits. Using multivariable logistic regression, associations between potential risk factors and HPV infection were estimated and expressed as odds ratios (ORs) with 95% confidence intervals (CI). Current cigarette smoking was associated with increased odds of HPV detection (OR = 1.2; 95% CI: 1.0–1.4), but we found no association with alcohol use in the analysis adjusted for sexual behavior. Circumcision reduced the odds of a prevalent HPV infection (OR = 0.7; 95% CI: 0.5–1.0) although not statistically significantly. Strong associations with lifetime and recent number of female sex partners were observed, but in contrast to uncircumcised men, increasing number of sex partners was not associated with higher HPV prevalence in circumcised men. In conclusion, smoking was associated with increased odds of penile HPV in men from the general population in Denmark, whereas circumcision seemed to reduce the risk. Moreover, our results indicated that there might be differences in the viral susceptibility between circumcised and uncircumcised men.

scholarly journals Risk Factors for Subsequent Cervicovaginal Human Papillomavirus (HPV) Infection and the Protective Role of Antibodies to HPV‐16 Virus‐Like Particles

2002 ◽  
Vol 186 (6) ◽  
pp. 737-742 ◽  
Author(s):  
Gloria Y. F. Ho ◽  
Yevgeniy Studentsov ◽  
Charles B. Hall ◽  
Robert Bierman ◽  
Leah Beardsley ◽  
...  
Keyword(s):  
Risk Factors ◽  
Human Papillomavirus ◽  
Hpv Infection ◽  
Protective Role ◽  
Hpv 16 ◽  
Virus Like Particles

Prevalence and risk factors of anogenital human papillomavirus infection in a community sample of men who have sex with men in Taiwan: baseline findings from a cohort study

2019 ◽  
Vol 96 (1) ◽  
pp. 62-66
Author(s):  
Carol Strong ◽  
Huachun Zou ◽  
Nai-Ying Ko ◽  
Ya-Lun Liang ◽  
Wen-Wei Ku ◽  
...  
Keyword(s):  
Risk Factors ◽  
Human Papillomavirus ◽  
Cost Effectiveness ◽  
Community Sample ◽  
Hpv Vaccination ◽  
Hpv Infection ◽  
Sex Partners ◽  
Anal Sex ◽  
The Past ◽  
Sex With Men

ObjectivesMen who have sex with men (MSM) are a highly neglected population in the current recommendation of girls-only human papillomavirus (HPV) vaccination programmes in many countries. To better assess the cost effectiveness of HPV vaccination among men requires data on the prevalence of HPV infection in MSM using a community sample, which is still sparse in several regions. We examined the prevalence of and factors associated with anogenital HPV infection among MSM in Taiwan.MethodsMSM 20 years of age and older were recruited from the community and social media in Taiwan in 2015–2016 and screened for HPV infection to detect 37 genotypes. MSM were seen at baseline and were/will be seen at 6, 12, 24 and 36 months. Men completed a questionnaire regarding their sexual experiences. Multivariable regression analyses were conducted to identify associated behavioural risk factors using the baseline data.ResultsA total of 253 MSM were recruited; 87 % were below 35 years of age. Diagnosis of HIV was reported in 4% of men; just over 20% had three or more anal sex partners in the past year. The prevalence of any tested HPV type was 29.4% at the anal site and 11% at the penile site. One quarter of MSM were infected with any of the 9-valent vaccine HPV types. Anal HPV detection was associated with having three or more receptive anal sex partners in the past year (adjusted odds ratio (aOR)=2.92, 95% CI 1.29 to 6.61) and having older sex partners (aOR=2.51, 95% CI 1.07 to 5.90).ConclusionsOur data provide the base to calculate the reproductive rate for HPV transmission in a low-risk community sample and cost-effectiveness to include men in HPV vaccination policies. Adding evidence from a community sample adds comprehensiveness for future estimates of disease transmission and vaccine effectiveness.

scholarly journals Understanding of risk factors for the human papillomavirus (HPV) infection based on gender and race

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Nosayaba Osazuwa-Peters ◽  
Eric Adjei Boakye ◽  
Rebecca L. Rohde ◽  
Rajan N. Ganesh ◽  
Ammar S. Moiyadi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Human Papillomavirus ◽  
Hpv Infection ◽  
Gender And Race

scholarly journals Incidence, Persistence, and Determinants of Human Papillomavirus: A Prospective Cohort Study of HIV-Negative Nigerian Women

2017 ◽  
Vol 3 (2_suppl) ◽  
pp. 39s-40s
Author(s):  
Sally N. Adebamowo ◽  
Michael Odutola ◽  
Ayotunde Famooto ◽  
Eileen Dareng ◽  
Amos Adebayo ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cohort Study ◽  
Human Papillomavirus ◽  
Standard Deviation ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Conflicts Of Interest ◽  
Hpv Infection ◽  
Nigerian Women ◽  
Hiv Negative

Abstract 63 Background: Cervical cancer is the second most common cancer in Africa. Persistent high-risk human papillomavirus (HRHPV) infection is a necessary cause but little is known about the persistence and associated risk factors of HRHPV infection in African women. We undertook this work to determine risk factors and the incidence of HPV infection in Nigerian women. Methods: ACCME is a multicenter, prospective cohort study of host germline, cervical somatic and HRHPV genomics, epigenomics, and vaginal microenvironment and their association with HPV. From February 2014 to January 2016, 10,000 HIV-negative women were enrolled in the cohort and are being observed every 6 months. We used SPF25/LiPA10 to characterize HPV infection and defined persistent infection as two consecutive positive tests performed at least 12 months apart. Logistic regression models were used to estimate associations between risk factors and persistent HPV. Results: The mean (± standard deviation) age of study participants at baseline was 40 (± 10) years, and mean (± standard deviation) vaginal pH was 5.2 (± 0.6). Approximately 42% of participants were positive for any HPV and 21% had persistence of any HPV infection. Some (35%) participants had multiple infections with any HPV. Approximately 54% of those with persistent any HPV infection had HRHPV—HPV type 52 (25%) and type 18 (15%) were the most prevalent and persistent HRHPV types. Incidence of any HPV infection was 6.6 per 1,000 person-months, whereas that of HRHPV was 2.6 per 1,000 person-months. Age, body mass index, education level, marital and socioeconomic status, and total number of lifetime sexual partners were associated with HPV infection in these women. Conclusion: We defined the incidence, risk factors, and most common types of HRHPV in a large cohort of women in West Africa. AUTHORS' DISCLOSURES OF POTENTIAL CONFLICTS OF INTEREST Sally N. Adebamowo No relationship to disclose Michael Odutola No relationship to disclose Ayotunde Famooto No relationship to disclose Eileen Dareng No relationship to disclose Amos Adebayo No relationship to disclose Peter Achara No relationship to disclose Bunmi Alabi No relationship to disclose Kayode Obende No relationship to disclose Richard Offiong No relationship to disclose Sanni Ologun No relationship to disclose Clement A. Adebamowo Speakers' Bureau: Merck

Prevalence and risk factors for oral human papillomavirus infection in 129 women screened for cervical HPV infection

Oral Oncology ◽  
2014 ◽  
Vol 50 (1) ◽  
pp. 27-31 ◽  
Author(s):  
Moritz F. Meyer ◽  
Christian U. Huebbers ◽  
Oliver G. Siefer ◽  
Julia Vent ◽  
Iris Engbert ◽  
...  
Keyword(s):  
Risk Factors ◽  
Human Papillomavirus ◽  
Hpv Infection ◽  
Human Papillomavirus Infection ◽  
Papillomavirus Infection

Risk factors associated with human papillomavirus infection status in a Korean cohort

2013 ◽  
Vol 142 (8) ◽  
pp. 1579-1589 ◽  
Author(s):  
H. LEE ◽  
D.-H. LEE ◽  
Y.-M. SONG ◽  
K. LEE ◽  
J. SUNG ◽  
...  
Keyword(s):  
Risk Factors ◽  
Human Papillomavirus ◽  
Contraceptive Use ◽  
Transmitted Disease ◽  
Multivariate Regression Analysis ◽  
Hpv Infection ◽  
Sexually Transmitted ◽  
Papillomavirus Infection ◽  
Behavioural Factors ◽  
Epidemiological Characteristics

SUMMARYBy surveying extensive epidemiological behavioural and sexual risk factors in a Korean twin cohort, risk factors for human papillomavirus (HPV) infection were investigated in South Korea. A total of 912 vaginal specimens were collected from the Healthy Twin Study, consisting of twins and their families. A range of epidemiological, behavioural, and sexual activity characteristics were evaluated using multivariate logistic regression analyses of family and twin relationships, adjusted to elucidate the risk factors for HPV infection. Of the various epidemiological characteristics, the possibility of extramarital affairs [odds ratio (OR) 2·48, 95% confidence interval (CI) 1·02–6·02] significantly increased the prevalence of HPV infection. Our multivariate regression analysis indicated that oral contraceptive use (OR 40·64, 95% CI 0·99–1670·7) and history of sexually transmitted disease (OR 2·56, 95% CI 0·93–7·10) were strongly associated with an increase in HPV infection. On the other hand, more frequent vaginal douching (OR 0·32, 95% CI 0·13–0·77) significantly decreased the prevalence of HPV infection. Our results suggested that HPV infection is associated with both biological and behavioural factors.

scholarly journals Papillomaviral infection: risk factors of cervical neoplastic progression

2004 ◽  
Vol 53 (3) ◽  
pp. 34-41
Author(s):  
Е. V. Shipitsyna ◽  
K. A. Babkina ◽  
Е. А. Orzheskovskaya ◽  
А. M. Savicheva
Keyword(s):  
Risk Factors ◽  
Cervical Cancer ◽  
Human Papillomavirus ◽  
P53 Gene ◽  
Hpv Infection ◽  
Neoplastic Progression ◽  
Protein Loss ◽  
Gene Encoding ◽  
Infection Risk Factors ◽  
Cell Genome

Human papillomavirus (HPV) plays the important role in the etiology of the cervical cancer. Considering that the cancer is very rare consequence of HPV-infection and even the high-grade lesions may spontaneously regress, search for the factors capable of predicting disease progression is of great significance. In the present review results of researches into risk factors of developing cervical cancer are summarized. Some virus-associated factors, such as infection with oncogenic types and variants of human papillomavirus, viral load, integration of viral DNA into cell genome, as well as host factors - polymorphism of p53 gene encoding a key apoptotic protein, loss of heterozygosity, tumor suppressor genes hypermethylation - are analyzed in terms of their prognostic value.

Prevalence of genital human papillomavirus DNA in a sample of senior school-aged women in the Australian Capital Territory

Sexual Health ◽  
2006 ◽  
Vol 3 (2) ◽  
pp. 91 ◽  
Author(s):  
Elissa J. O'Keefe ◽  
Anne Gardner ◽  
Marian J Currie ◽  
Suzanne Garland ◽  
Sepehr Tabrizi ◽  
...  
Keyword(s):  
Risk Factors ◽  
High School ◽  
Human Papillomavirus ◽  
Young Women ◽  
Hpv Infection ◽  
Senior High School ◽  
Sexually Active ◽  
Australian Capital Territory ◽  
Hpv Dna ◽  
Australian Capital

Background: A strong association between persistent infection with oncogenic types of human papillomavirus (HPV) and cervical cancer is well established. Small numbers of international studies examining adolescent HPV infection and the risk factors associated are published, but there is currently no evidence on the prevalence and risk factors for HPV in an Australian, sexually active female adolescent population. Methods: To provide prevalence and risk factors for HPV in a female sexually active, senior high school population in the Australian Capital Territory (ACT), a convenience sample of 161, 16–19-year-old females attending a senior high school was evaluated. The sample formed part of a larger sample recruited for a study of sexually transmitted infections and blood-borne viruses in senior high school students. A clinical record was used to collect information about sexual and other risk behaviours, while self-collected vaginal swabs were tested for HPV DNA detection and genotyping using polymerase chain reaction. Results: The prevalence of HPV DNA in this sample overall was 11.2%, with multiple genotypes in 38%. No statistically significant associations were found between HPV DNA and the number of male partners, age of coitarche, time since first sexually active, condom use, smoking or alcohol intake. Conclusions: This is the first Australian study that has examined the prevalence and risk factors for genital HPV in this demographic group. The prevalence of HPV infection is slightly lower than reported in similar age groups overseas and is lower than other Australian studies in older women and those attending sexual health centres. Of HPV-positive young women, high-risk genotypes were found in over half, with more than one-third of HPV existing as multiple genotypes. Large community-based prevalence studies are needed to guide the development of recommendations for the vaccination of young women against HPV and to support other health promotion initiatives.

Sign in / Sign up

Export Citation Format

Share Document