scholarly journals ROLE OF CLIMATE IN PRACTICE OF PANCHAKARMA: A CRITICAL REVIEW

2021 ◽  
Vol 12 (1) ◽  
pp. 96-100
Author(s):  
Hemant . ◽  
Shreyas DM ◽  
Kiran M Goud
Keyword(s):  
Healthy Person ◽  
Climatic Conditions ◽  
The Other ◽  
Climate Factors ◽  
Climate Classification ◽  
Direct Role ◽  
Climate Conditions ◽  
Köppen Climate Classification ◽  
Moderate Climate

Ayurveda is a science of life focusing not only to cure the Rogi but also towards the maintenance of the health of a healthy person. Panchakarma is a modality giving a variety of opportunities to fulfill the main aim of Ayurveda. There are lots of factors which are involved to certainly administer therapy in such a way that it will always be infallibly effective. Among all those factors climate or Kala is one of the factors which influences almost every aspect in one way or the other. Today the Koppen Climate classification gives us the background to understand the climatic conditions in various places. These climate conditions will occur according to the Desha also, so Desha plays a direct role in influencing the Kala factor as Six seasons are not to be found everywhere around the globe. This variation of the seasons makes difficult for the physician to apply the concepts of Ritu and Shodhana accordingly for e.g., a place like Bengaluru has a moderate climate all over year yet being near to equator as compare to other cities in Karnataka because of the height from seas level. Therefore, an understanding of comparing the current seasons of cities based on distance from equator, height from sea level with the Sadharana and Asadharana Ritu for commencing the Sukhatama Vamanadi Karma is needed. Therefore, an attempt is made to describe the entire possible climate factors which play a role in commencing the Panchakarma therapies effectively.

scholarly journals RNA polymerase II plays an active role in the formation of gene loops through the Rpb4 subunit

2019 ◽  
Vol 47 (17) ◽  
pp. 8975-8987 ◽  
Author(s):  
Paula Allepuz-Fuster ◽  
Michael J O’Brien ◽  
Noelia González-Polo ◽  
Bianca Pereira ◽  
Zuzer Dhoondia ◽  
...  
Keyword(s):  
Rna Polymerase ◽  
Rna Polymerase Ii ◽  
Essential Role ◽  
Transcription Termination ◽  
Active Role ◽  
The Other ◽  
Loop Formation ◽  
Direct Role

AbstractGene loops are formed by the interaction of initiation and termination factors occupying the distal ends of a gene during transcription. RNAPII is believed to affect gene looping indirectly owing to its essential role in transcription. The results presented here, however, demonstrate a direct role of RNAPII in gene looping through the Rpb4 subunit. 3C analysis revealed that gene looping is abolished in the rpb4Δ mutant. In contrast to the other looping-defective mutants, rpb4Δ cells do not exhibit a transcription termination defect. RPB4 overexpression, however, rescued the transcription termination and gene looping defect of sua7-1, a mutant of TFIIB. Furthermore, RPB4 overexpression rescued the ssu72-2 gene looping defect, while SSU72 overexpression restored the formation of gene loops in rpb4Δ cells. Interestingly, the interaction of TFIIB with Ssu72 is compromised in rpb4Δ cells. These results suggest that the TFIIB–Ssu72 interaction, which is critical for gene loop formation, is facilitated by Rpb4. We propose that Rpb4 is promoting the transfer of RNAPII from the terminator to the promoter for reinitiation of transcription through TFIIB–Ssu72 mediated gene looping.

Darwin’s legacy II: why biology is not physics, or why it has taken a century to see the dependence of genes on the environment

Genome ◽  
2015 ◽  
Vol 58 (1) ◽  
pp. 55-62 ◽  
Author(s):  
Rama S. Singh
Keyword(s):  
Natural Selection ◽  
20Th Century ◽  
The Other ◽  
Paradigm Change ◽  
Phenotypic Evolution ◽  
Direct Role ◽  
Theory Of Evolution ◽  
Genes And Environment ◽  
Teleological Interpretation

Genes and environment make the organism. Darwin stood firm in his denial of any direct role of environment in the modification of heredity. His theory of evolution heralded two debates: one about the importance and adequacy of natural selection as the main mechanism of evolution, and the other about the role of genes versus environment in the modification of phenotype and evolution. Here, I provide an overview of the second debate and show that the reasons for the gene versus environment battle were twofold: first, there was confusion about the role of environment in modifying the inheritance of a trait versus the evolution of that trait, and second, there was misunderstanding about the meaning of environment and its interaction with genes in the production of phenotypes. It took nearly a century to see that environment does not directly affect the inheritance of a phenotype (i.e., its heredity), but it is nevertheless the primary mover of phenotypic evolution. Effects of genes and environment are not separate but interdependent. One cannot separate the effect of genes from that of environment, or nature from nurture. To answer the question posed in the title, it is partly because the 20th century has been a century of unending progress in genetics. But also because unlike physics, biology is not colorblind; progress in biology has often been delayed beyond the Kuhnian paradigm change due to built-in interest in negating the influence of environment. Those who are against evolution, of course, cannot be expected to understand the role of environment in evolution. Those for it, many biologists included, believing in the supremacy of genes empowers them by giving adaptation a solely gene-directed (self-driven) “teleological” interpretation.

scholarly journals Effect of early contamination by Botrytis cinerea on the development of Grey mould on Muscat d’Italie in Tunisian vineyard

OENO One ◽  
2004 ◽  
Vol 38 (2) ◽  
pp. 131
Author(s):  
Samir Chebil ◽  
Jean Roudet ◽  
Abdelwahed Ghorbel ◽  
Bernadette Dubos
Keyword(s):  
Statistical Analysis ◽  
Botrytis Cinerea ◽  
Grey Mould ◽  
Climatic Conditions ◽  
The Other ◽  
Economic Losses ◽  
Maturation Stage ◽  
Significant Relationships ◽  
Very High

<p style="text-align: justify;">Grey rot, caused by <em>Botrytis cinerea</em>, is nowadays the most damaging disease of the Tunisian vineyard. The fungus attacks berries at the maturation stage and causes important economic losses. The protection of vineyard against this disease is very difficult due to the fungus characteristics. In fact <em>B. cinerea</em> is in the border of parasitism and saprophytism, in pre-veraison it usually survive as saprophyte then it attacks berries before their maturation. The purpose of this study is to highlight the role of pre-veraison’s contamination by <em>B. cinerea</em> on the development of the Grey rot on the berries after veraison.</p><p style="text-align: justify;">The results revealed that at the pre-veraison stage, <em>B. cinerea</em> grows as a saprophyte. The fungus’s rate presence is low on the barks (less than 10 %), very high on the floral buds (between 5 and 27 %) and relatively high in the immature berries (about 20 %). The quantification of bunches pollution, showed that the rate of contaminations by <em>B. cinerea</em> is very high (more than 70 %).</p><p style="text-align: justify;">On the other hand, the mapping out showed up that outbreak of the disease happened after veraison on Muscat d’Italie. Also, the rate of berries’ rot, were different each year, in relation to the climatic conditions and plant’s physiology. We found that the rate of rot inside bunches is relatively high (between 15 and 40 %) due to condia on stem or <em>B. cinerea</em> latent. The statistical analysis showed significant relationships between the rate of latent <em>B. cinerea</em> and the appearance of the disease after the veraison stage. Also, the scoring of conidia observed in the air showed a big activity of the fungus during flowering and the maturation of berries.</p>

scholarly journals EPIDEMIOLOGICAL FEATURES OF COMMUNITYACQUIRED PNEUMONIA UNDER EXTREME NATURAL-CLIMATIC CONDITIONS

2017 ◽  
pp. 53-56
Author(s):  
R.S. Rakhmanov ◽  
N.N. Potekhina ◽  
I.A. Grishin ◽  
Yu.G. Piskarev ◽  
V.N. Basalyga ◽  
...  
Keyword(s):  
Body Weight ◽  
Environmental Factors ◽  
Community Acquired Pneumonia ◽  
Climatic Conditions ◽  
Natural Resistance ◽  
Seasonal Prevalence ◽  
Climate Conditions ◽  
Epidemiological Features ◽  
Causative Agents

The authors evaluated epidemiological features of community-acquired pneumonia (CAP) in organized groups under hot and wet conditions of Black Sea climate as well as under maritime climate conditions of Kamchatka. Persons of first group were not adapted to activity conditions and not acclimatized, but persons of second group were acclimatized and adapted to activity conditions. It was established that environmental factors caused incidence rate, seasonal prevalence, phase of ascent during period of adaptation, prevalence of causative agents. CAP incidence among persons with body weight deficiency, its onset in stress situations, high associativity of opportunistic microorganisms in etiological structure provided evidence about a role of natural resistance of human body. It was found a necessity of application of means of non-specific and specific prevention taking into consideration etiological role of causative agents both in different times during period of adaptation and taking into account season.

scholarly journals Association between Climatic Conditions, Population Density and COVID-19 in Indonesia

2021 ◽  
Vol 50 (3) ◽  
pp. 879-887
Author(s):  
AZIZAH R. ◽  
SANTI MARTINI SANTI MARTINI ◽  
LILIS SULISTYORINI LILIS SULISTYORINI ◽  
MAHMUDAH MAHMUDAH ◽  
ADITYA SUKMA PAWITRA ◽  
...  
Keyword(s):  
Population Density ◽  
Air Temperature ◽  
Virus Disease ◽  
Climatic Conditions ◽  
Cluster Method ◽  
Tropical Region ◽  
Climate Factors ◽  
Climate Conditions ◽  
Exact Test ◽  
Populated Region

The first emergence of Corona Virus Disease 2019 (COVID-19) confirmed cases found in Wuhan, China, has become a global crisis. At least 177 countries have been affected over 43,000,000 confirmed cases of corona positive and more than one million deaths until October 27th, 2020. Recent research has analyzed any possible factors causing the COVID-19 spreads were climate factors and population density. Indonesia was a tropical region known as the high-populated country in the World, with a 52.9% area with a high mean air temperature and over 267.7 million populations. Our study aims to analyze the correlation between climate, population density, and COVID-19 in Indonesia. We used the K-means cluster method and Fisher’s exact test to determine climatic conditions, population density, and COVID-19 clusters and study the correlation. Our research found that there is a correlation between climatic conditions and population density with COVID-19 (p: 0,034; p:0,004). Warmer climate conditions and densely populated regions contributed to the risen COVID-19 transmission in Indonesia. These are highlighted by the evidence of the top six provinces with highest COVID-19 cases are province classified in warmer climatic conditions (high air temperature, low rainfall, and humidity) and a fairly-dense to densely populated region.

scholarly journals Measures to Prevent and Combat Pear Scab (Venturia pirina) in the Climate Conditions of Lapusel

2016 ◽  
Vol 73 (2) ◽  
pp. 271
Author(s):  
Lucia Mihălescu ◽  
Zorica Voşgan ◽  
Oana Mare Roşca ◽  
Monica Marian ◽  
Stela Jelea ◽  
...  
Keyword(s):  
Climatic Conditions ◽  
The Other ◽  
Climate Data ◽  
Attack Frequency ◽  
Climate Conditions ◽  
Pear Scab ◽  
Venturia Pirina ◽  
Biological Effectiveness ◽  
Favourable Development ◽  
Frequency Intensity

In this paper we studied the emergence and development of pear scab (Venturia pirina), as well as the combat methods, testing a couple of fungicides. The aim of the research has been to highlight the resistance, respectively the sensitivity of some pear varieties against the fungi attack, in order to make recommendations for the new plantations, as well as the testing of 7 fungicides, remarking the product with the highest biological effectiveness. The researches were conducted in the years 2013-2014 at the company SC Mecanochim Lapusel, Maramures County. The experiments were conducted on plots planted with the Olivier de Serres and Bergamotte Crassane varieties. The attack was calculated determining the attack frequency, intensity and degree. The linear-interrupted method was used, comprising 3 variants of 5 trees each. Analyzing the climate data, it has resulted that in 2013 scab had favourable development and attack conditions. The Olivier de Serres variety was noted for its resistance to fungus attack, with a frequency of 0.2-1.3% on fruits and insignificant frequency on leaves, for all 7 tested product variants. The Bergamotte Crassane variety was placed on the other end, with a higher frequency and intensity, both on fruits (2-3%) and on leaves (2.5-3.5%). The infections diminished in 2014 due to the unfavourable climatic conditions. Three products had better results, from the seven tested products, thus: Alcupral 50PU, Stroby DF and Chorus 50 WG.  

scholarly journals Temperature and Imbibition Influence Serianthes Seed Germination Behavior

Plants ◽  
2019 ◽  
Vol 8 (4) ◽  
pp. 107 ◽  
Author(s):  
Marler
Keyword(s):  
Seedling Emergence ◽  
The Other ◽  
Quadratic Model ◽  
Physical Dormancy ◽  
Direct Role ◽  
Linear Pattern ◽  
Linear Slope ◽  
Natural Settings ◽  
Seed Respiration

The direct role of physical dormancy in delaying germination of Serianthes grandiflora Bentham, Serianthes kanehirae Fosberg, and Serianthes nelsonii Merrill seeds has not been adequately studied, nor has the role of temperature on germination behaviors. Imbibition testing indicated seeds with scarified testa absorbed water for the duration of a 24 h imbibition period, but seeds with an intact testa stopped absorbing water after 1 h. The behavior of S. nelsonii seeds most closely matched those of S. kanehirae, with the pattern of water absorption for S. grandiflora seeds deviating from that for the other species. Scarified seeds germinated readily, with initial germination occurring by 50 h for S. nelsonii and 90 hr for the other species, and maximum germination of 80% to 90% occurring by 60 h for S. nelsonii and 100 h for the other species. Predicted optimum temperature based on a fitted quadratic model was 26 °C for S. nelsonii, 23 °C for S. grandiflora, and 22 °C for S. kanehirae. Seed respiration increased within 3 h of imbibition for scarified seeds and continued to increase in a linear pattern. The linear slope was greatest for S. nelsonii, intermediate for S. grandiflora, and least for S. kanehirae, but ultimate respiration was greatest for S. kanehirae seeds. Seed respiration was so limited for un-scarified seeds that the instrument was unable to quantify any carbon dioxide efflux. Physical dormancy in seeds of these Serianthes species is a powerful trait that spreads out the timing of seedling emergence in natural settings and controls imbibition and germination speed in managed nurseries.

scholarly journals Variability of hygro-climatic conditions of forest vegetation in Poland during the period of 1951–2015

2018 ◽  
Vol 79 (2) ◽  
pp. 139-146
Author(s):  
Mariusz Siedlecki
Keyword(s):  
Linear Trend ◽  
Critical Value ◽  
Climatic Conditions ◽  
Forest Vegetation ◽  
The Other ◽  
Wood Production ◽  
Climate Conditions ◽  
Daily Data ◽  
Annual Biomass ◽  
Trend Coefficient

Abstract This work presents an assessment of changes in the hygro-climatic conditions determining the vegetation and productivity of forest areas. Selected indices such as the radiant index of climate aridity – RIA, optimal precipitation – Popt, critical value of precipitation – Pkrt and CVP index (Climate, Vegetation, Productivity), which describe annual biomass and wood production under climatic conditions, were used. The analysis is based on standard meteorological measurements taken from 21 stations from the period of 1951–2015. The daily data were employed to calculate the previously mentioned indices, and the next linear trend coefficient was used to assess changes in hygro-climatic conditions. The results show an increasing tendency towards dry climate conditions (positive values of the RIA linear trend coefficient) in a large part of the area consisting of Wielkopolska, the Silesian lowlands, and southern Poland. These areas are also characterized by the fastest increase in the most favourable sum of precipitation Popt and critical precipitation Pkrt for forest vegetation. This means that water resources in the environment and hygro-climatic conditions important for vegetation and the productivity of forest vegetation are deteriorating. On the other hand, the results of the CVP change assessment show an improvement in the climatic conditions influencing vegetation and forest productivity. The greatest positive changes of the CVP index are observed in the areas of south-eastern Poland.

scholarly journals Genetic Analysis of Myc and Telomerase Interactions In Vivo

2006 ◽  
Vol 26 (16) ◽  
pp. 6130-6138 ◽  
Author(s):  
Ignacio Flores ◽  
Gerard Evan ◽  
María A. Blasco
Keyword(s):  
Transcription Factor ◽  
Target Genes ◽  
The Other ◽  
Induced Response ◽  
Direct Role ◽  
Myc Gene ◽  
Late Generation ◽  
Transcriptional Target

ABSTRACT Myc is a transcription factor with pleiotropic effects on tumorigenesis which are likely to be mediated by its target genes. A known Myc transcriptional target is the catalytic subunit of telomerase, Tert. However, the contribution of Tert activation to Myc-induced tumorigenesis in vivo remains unknown. In this study, we addressed the role of telomerase in Myc-induced skin papillomatosis by using compound mice with a switchable Myc gene, Inv-MycERTAM mice, in combination with either telomerase deficiency (Terc−/−) or telomerase overexpression (K5-mTert) in the skin. We first demonstrated that Myc activates telomerase in the skin. With Inv-MycERTAM × Terc−/− mice, we further showed that this telomerase activation is partially required to elicit a full hyperplastic Myc-induced response. The presence of critically short telomeres in late-generation Inv-MycERTAM × Terc−/− mice further reduced the skin lesion induced by Myc. On the other hand, telomerase overexpression in the skin of K5-mTert mice augments Myc-induced hyperplasia in the absence of changes in telomere length, suggesting a direct role of telomerase in the Myc protumorigenic response. Taken together, these results highlight telomerase as a mediator of Myc-induced papillomatosis and suggest telomerase as a putative therapeutic target for Myc-dependent lesions.

scholarly journals Multivariate Analysis of the Effect of Climate Conditions on Gold Production in Ghana

2018 ◽  
Vol 18 (1) ◽  
pp. 72-77
Author(s):  
Sampson Takyi Appiah ◽  
Albert Buabeng ◽  
N. K. Dumakor-Dupey
Keyword(s):  
Time Series ◽  
Regression Models ◽  
Relative Effect ◽  
Climatic Conditions ◽  
Standard Errors ◽  
Climate Factors ◽  
Gold Production ◽  
Planning And Scheduling ◽  
Climate Conditions ◽  
Production Planning And Scheduling

The change in climatic conditions and its catastrophic effect on mining activities has become a source of worry for mining industries and therefore needs due attention. This study examined the effect some climate factors have on gold production in Ghana. First, a direct Multiple Linear Regression was applied on the climate factors with the aim of determining the relative effect of each factor on gold production which exhibited a time series structure. The consequence is that, the estimates of the coefficients and their standard errors will be wrongly estimated if the time series structure of the errors is ignored. In order to eliminate these deficiencies and better understand the effect of these climate factors on gold production, regression with ARIMA errors technique was employed after its appropriateness has been tested. The model was then compared in terms of prediction accuracy which resulted a MAPE of 9.78%. It was concluded that, gold production in Ghana is positively related to Temperature whilst negatively to Rainfall and Precipitate. It was recommended that mine operators in Ghana could base on this analysis to optimise their production planning and scheduling. Keywords: Gold Production, Climate, Multicollinearity, VIF, Regression Models with ARIMA Errors

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