scholarly journals Novel Association between Gemfibrozil and Dyslipidemia: A Case Report

Author(s):  
Deena M. S. Barrouq ◽  
Tareq Irshaidat

Dyslipidemia is a risk factor in many health complications, among them is hypertension. Case: This report presents a case of a poorly controlled dyslipidemia that could not be managed by medications. A surprisingly and an unexpected factor interfered; the triglyceride-lowering medication caused a significant increase in the appetite toward fat-rich food items which opposed its intended purpose. Methodology: A dietary intervention and an uncommon drug dose modification were necessary. Results: The personally designed protocol led to a significant overall improvement and was successful in adjusting the biochemical parameters especially the plasma triglycerides and the total cholesterol and was effective in reversing hypertension and a pre-diabetic state to safer values. Conclusion: This is the first characterized case in the literature on the involvement of gemfibrozil in poor management of dyslipidemia.

Author(s):  
Francisco Sousa ◽  
Joana Vicente ◽  
Sara Azevedo ◽  
Ana Pinto ◽  
Cecília Sousa

2021 ◽  
pp. 101642
Author(s):  
Anahita Ansari Djafari ◽  
Katayoun Hasanzadeh ◽  
Homa Masrour ◽  
Mahsa Ahadi ◽  
Majid Dargahi ◽  
...  

2021 ◽  
pp. 152660282110250
Author(s):  
Barbara Infante ◽  
Adelaide Di Lorenzo ◽  
Dario Troise ◽  
Angela M. R. Ferrante ◽  
Maurizio Ruggieri ◽  
...  

Pseudoaneurysm is due to a disruption in arterial wall continuity. It forms a sac that communicates with the vessel lumen and is surrounded by the compressed, surrounding tissues and not by the wall of the artery from which the lesion arises. Many causes can predispose to the formation of a pseudoaneurysm such as trauma, surgical procedures, anticoagulation. In our patient another important risk factor for the formation of a pseudoaneurysm is ADPKD (autosomal dominant polycystic kidney disease) that can cause vascular complication. The mechanisms leading to the genesis of the pseudoaneurysms in our patient are unknown, but the clinicians should bear in mind when evaluating this type of patients that ADPKD may have a various range of systemic cardiovascular manifestation.


2001 ◽  
Vol 87 (2) ◽  
pp. 111-112
Author(s):  
Jon Matthews ◽  
Giles W Beck ◽  
Douglas M G Bowley ◽  
Andrew N Kingsnorth

AbstractThe case of a 31 year old male presenting as an emergency with a recurrent colonic volvulus is described. A chest X-ray on admission to hospital showed the presence of hepato-diaphragmatic interposition of the colon, Chilaiditi’s Sign, which is known to be a risk factor for colonic volvulus. This is only the fourth reported case of colonic volvulus in association with Chilaiditi’s Syndrome and the first with recurrent colonic volvulus. The optimal treatment for recurrent volvulus in patients with risk factors such as Chilaiditi’s Syndrome or megacolon is also discussed.


2008 ◽  
Vol 90 (5) ◽  
pp. 2008.e13-2008.e16 ◽  
Author(s):  
Ozren Grgic ◽  
Branko Radakovic ◽  
Dubravko Barisic

2020 ◽  
pp. 1-4

The current case report is presenting a post her third cesarean delivery COVID-19 infected woman who was 35years old, morbidly obese, and asthmatic. As coronavirus disease 2019 (COVID-19) is a new disease, its information is constantly being updated. Earlier reports of COVID 19 claims that pregnancy did not affect the progress of the disease severity. Recently, the Centers for Disease Control and Prevention (CDC) announced that pregnancy is a risk factor for COVID-19 severity. In the current case, her pregnancy may aggravate the criticality of COVID-19 infection in the addition to of her other risk factors (age, asthma, and obesity) up to death.


2020 ◽  
Vol 12 (1) ◽  
pp. e2020079
Author(s):  
Margherita Mauro ◽  
Giuliana Lo Cascio ◽  
Rita Balter ◽  
Ada Zaccaron ◽  
Elisa Bonetti ◽  
...  

  Background Invasive mucormycosis is a very aggressive fungal disease among immunocompromised pediatric patients caused by saprophytic fungi that belong to the order of the Mucorales. Case Report We describe a case of  of Lichtheimia corymbifera infection in a 15-year-old child with B-cell Non-Hodgkin Lymphoma (NHL) involving lung, kidney and thyroid that initially was diagnosed as probable aspergillosis delaying the effective therapy for mucormycosis. Conclusions This case showed that also intensive chemotherapy with rituximab may represent a risk factor for mucormycosis infection. Liposomal amphotericin B and surgery  remain  key tools  for a successful treatment of this aggressive disease. 


2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Kevin Maki ◽  
Orsolya Palacios ◽  
Mary Buggia ◽  
Mary Dicklin ◽  
Marjorie Bell ◽  
...  

Abstract Objectives To assess the effect of breakfast egg intake, vs. energy-matched carbohydrate (CHO)-based foods, on insulin sensitivity and markers of cardiometabolic health in adults at-risk for type 2 diabetes. Methods Overweight or obese adults with prediabetes and/or metabolic syndrome were included in this randomized crossover study consisting of two 4-wk dietary intervention periods, separated by a ≥4 wk washout. During each intervention, subjects consumed study products containing either 2 eggs/d for 6 d/wk (12 eggs/wk) or energy-matched CHO-based foods for breakfast. Percent changes from baseline were assessed for insulin sensitivity; CHO metabolism; lipid metabolism, including lipoprotein lipids, subfactions and particle sizes; high-sensitivity C-reactive protein (hs-CRP); and blood pressures (BP). Results Overall, 30 subjects (11 male; 19 female) with mean age of 53.5 ± 1.9 y and body mass index (BMI) of 31.9 ± 0.7 kg/m2 provided evaluable data. Median low-density lipoprotein cholesterol (LDL-C) decreased by 6.0% from a baseline of 119 mg/dL after 4-wk intake of the CHO breakfast foods, which was larger than the 2.9% reduction during the egg condition (P = 0.023 between diets). Mean systolic blood pressure was reduced significantly more during the egg condition vs. the CHO condition (2.7% vs. 0.0%, respectively, P = 0.018) from a baseline value of 127 mmHg. None of the other cardiometabolic risk factor parameters showed significant differences in response between diet conditions. Conclusions Intake of 12 eggs/wk for breakfast, vs. energy matched CHO-based foods, did not adversely affect the cardiometabolic risk factor profile in men and women at risk for diabetes. Funding Sources American Egg Board/Egg Nutrition Center, Park Ridge, IL Supporting Tables, Images and/or Graphs


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