scholarly journals Assessment of Health Risk of Daily Fluoride Intake of Some Selected Dentifrices used in Port Harcourt, Nigeria

2021 ◽  
pp. 1-8
Author(s):  
Kpalap, Pretty Tonubari ◽  
Bartimaeus, Ebirien-Agana Samuel ◽  
Brown, Holy
Keyword(s):  
Health Risk ◽  
Ph Value ◽  
Hazard Quotient ◽  
Fluoride Concentration ◽  
Daily Intake ◽  
The Other ◽  
Fluoride Intake ◽  
Port Harcourt ◽  
The Aesthetic ◽  
Ph Range

Background: Several dentifrices are marketed and used by individuals for the purposes of cleaning and maintaining the aesthetic and health of the teeth, promote oral hygiene and aid in removal of dental plaque and food materials from the teeth. This study was thus designed to assess the pH and fluoride concentrations in selected dentifrices and the possible health risks associated with daily fluoride intake of these selected dentifrices used in Port Harcourt, Nigeria. Materials and Methods: This study estimated the pH and fluoride concentration of the different dentifrices by the pH meter and Ion Selective Electrode method. In addition, the Daily fluoride intake (DFI), Chronic daily intake (CDI) and Hazard quotient (HQ) for the different dentifrices to assess the risk of fluoride intake was calculated. Results: From the result of this study, it was noticed that only one dentifrice, chewing stick (Massularia acuminate) has a pH (6.8) that conform to the recommended pH range (6.0-7.5) by NAFDAC while the other dentifrices have a pH value (7.6-10.1) that was higher than the pH range recommended by NAFDAC. For the fluoride concentration, it was observed that some of the dentifrices like Dr. Agnes Nwanmma dental powder (440 ppm), Dr. White dental powder (480 ppm) and Eradental powder (760 ppm) have low fluoride concentration when compared with the fluoride standard concentration stipulated by SON/ NAFDAC (825-1250 ppm) while the other dentifrices showed fluoride concentration within the range stipulated by stipulated by SON/ NAFDAC but they were below the fluoride concentrations stated on their different labels. The DFI of the dentifrices was within the range (53.86-131.58 mg/day), CDI (0.744-1.8275 mg/kg/day and the HQ (12.27-30.46). Conclusion: Although the fluoride concentrations of the dentifrices were within the normal range as stipulated by NAFDAC and SON, the observation of HQ > 1 in all the dentifrices implied that dentifrices commonly used in Nigeria may pose health risk to the consumers.

scholarly journals Non-Carcinogenic Health Risk Assessment due to Fluoride Exposure from Tea Consumption in Iran Using Monte Carlo Simulation

2019 ◽  
Vol 16 (21) ◽  
pp. 4261 ◽  
Author(s):  
Mohammad Amin Karami ◽  
Yadollah Fakhri ◽  
Shahabaldin Rezania ◽  
Abdol Azim Alinejad ◽  
Ali Akbar Mohammadi ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Health Risk ◽  
Health Risk Assessment ◽  
Environmental Protection Agency ◽  
Hazard Quotient ◽  
Age Groups ◽  
Fluoride Concentration ◽  
Daily Intake ◽  
Carcinogenic Risk ◽  
Fluoride Exposure

Excessive intake of fluoride can cause adverse health effects. Consumption of tea as a popular drink could be a potential source of fluoride exposure to humans. This research aimed to evaluate the fluoride concentration in tea among the Iranian people using the available data in the literature and to assess the health risk related to the consumption of tea in men, women, and children. The health risk assessment was conducted using the chronic daily intake and hazard quotient according to the approach suggested by the Environmental Protection Agency. The fluoride content in published studies varied noticeably, ranging from 0.13 to 3.27 mg/L. The results revealed that the hazard quotient (HQ) in age groups of women (21–72 years) and children (0–11 years) was within the safe zone (HQ < 1) which showed that there was no potential of non-carcinogenic risk associated with drinking tea in these groups. However, in one case of the men (21–72 years), the HQ > 1 which shows a probable risk of fluorosis. The order of non-carcinogenic health risks in the studied groups was in the order of men > women > children. The results of this can be useful for organizations with the responsibility of human health promotion.

scholarly journals Risk Assessment of Poisonous Metals in Water and Soil at Two Abandoned Lead-Zinc Mines at Yonov, Benue State

2021 ◽  
pp. 1-14
Author(s):  
Samuel N. Paul ◽  
Bolaji B. Babatunde
Keyword(s):  
Risk Assessment ◽  
Health Risk ◽  
Hazard Quotient ◽  
Daily Intake ◽  
Sudden Change ◽  
Hazard Index ◽  
Soil Samples ◽  
Port Harcourt ◽  
Lead Zinc ◽  
Mean Concentration

Aim: The study was aimed at determining the risk assessment of toxic metal concentration in soil and water at two abandoned Lead-Zinc mines Yonov District, Logo, Benue State, Nigeria. Study design:  comparative cross-sectional study. Place and duration of study: This study was carried out at the Bruce Powel Toxicology & Biodiversity Laboratory, Animal and Environmental Biology Department, University of Port Harcourt, Analysis at Giolee Global Services Limited Port Harcourt, Nigeria from 16th July to 30th October 2019. Methodology: Eighteen composite water and soil samples were collected and analyzed using Atomic Absorption Spectrophotometer. Results: The mean concentration of Lead (Pb) was higher than that of Zinc (Zn) in all eighteen samples, while, Mercury (Hg) and Cadmium (Cd) were below detection limit in all samples. Mean concentration for Pb in soil samples in the order SiteII>Site I (1.29±0.134 mg/kg>1.26±0.04mg/kg) >control 0.82±0.06 mg/kg. Zn was higher in site I, 0.70±0.10 mg/kg than site II 0.66±0.04mg/kg, and control 0.42±0.02mg/kg. Pb values in water was similar in both sites at 0.46±0.04/0.02 mg/L, while control 0.02±0.001mg/kg. Zn was higher in site II 0.05±0.01mg/L than site I 0.04±0.01Mg/L, control was 0.004±0.00 mg/L. Health risk assessment showed that Estimated daily intake of metals, hazard quotient, hazard index were all less than 1, Carcinogenic risk was within the stipulated ranged of 10-6 to 10-4. Conclusion: Ecological and health risk indices revealed non-contamination by Poisonous metals, however, routine assessment is recommended to forestall any sudden change in the concentration that may result to deleterious effects on human health.

The Influence of Compost Amendments on Bioaccumulation of Potentially Toxic Elements by Pea Plant Cultivated in Mine Degraded Soils

2021 ◽  
Author(s):  
Muhammad Irfan ◽  
Muhammad Azhar Shah ◽  
Mehboob Alam ◽  
Anwarzeb Khan ◽  
Muhammad Amjad Khan ◽  
...  
Keyword(s):  
Plant Growth ◽  
Health Risk ◽  
Hazard Quotient ◽  
Daily Intake ◽  
Organic Amendments ◽  
Organic Fertilizers ◽  
Growth And Yield ◽  
Garden Soil ◽  
Target Hazard Quotient ◽  
Mining Soils

Abstract Potential toxic metals (PTEs) accumulation in soil and water is one of the major sources of food crop contamination. PTEs remediation from soil can be enhanced by addition of organic matter to the growing media. An experiment was carried out to investigate the effect of different organic amendments on the accumulation of PTEs in pea plant grown on mine degraded soils. Mining soils from chromite mine (CM), soap stone mine (SSM), manganese mine (MM) and quartz mine (QM) were mixed with vermicompost (VC), leaf mould (LC) and spent mushroom compost (SMC) along with garden soil at 1:1:1 ratio. Various growth and yield related attributes of pea plant as well as PTEs concentrations in soil and plants were studied. The highest Cd (2.62 mg kg−1) and Cr (13.6 mg kg−1) concentration was reported in CM soil, while Pb (23.3 mg kg−1) and Mn (59.2 mg kg−1) concentration in SSM and MM soil, respectively. Mining soils significantly reduced the plant growth and yield, while organic amendments reduced the PTEs availability and increased pea plant growth. Comparing the various organic fertilizers used, it was observed that VC efficiently reduced Cd, Cr, Pb and Mn uptake by pea plant, subsequently, improved pea plant growth. In order to assess the effects of various amendments on PTEs health risk reduction various risk indices including, plant trafser factor, average daily intake, health risk, target hazard quotient and target cancer risk were also calculated and the results revealed that application of compost particularly VC significantly reduced the dietary intake and health risks of PTEs.

scholarly journals Health Risk Assessment and Source Apportionment of Mercury, Lead, Cadmium, Selenium, and Manganese in Japanese Women: An Adjunct Study to the Japan Environment and Children’s Study

2020 ◽  
Vol 17 (7) ◽  
pp. 2231 ◽  
Author(s):  
Chaochen Ma ◽  
Miyuki Iwai-Shimada ◽  
Nozomi Tatsuta ◽  
Kunihiko Nakai ◽  
Tomohiko Isobe ◽  
...  
Keyword(s):  
Health Risk ◽  
Indoor Air ◽  
House Dust ◽  
Hazard Quotient ◽  
Daily Intake ◽  
Essential Elements ◽  
Health Concern ◽  
Potential Health ◽  
Mean Values ◽  
Miyagi Prefecture

Toxic element pollution is a serious global health concern that has been attracting considerable research. In this study, we elucidated the major routes of exposure to three toxic elements (mercury, cadmium, and lead) and two essential elements (manganese and selenium) through diet, soil, house dust, and indoor air and assessed the potential health risks from these elements on women from the coastal area of Miyagi prefecture, Japan. Twenty-four-hour duplicate diet, house dust, soil, and indoor air samples were collected from 37 participants. Cd, Pb, Mn, and Se concentrations were measured using inductively coupled plasma mass spectrometry, and Hg concentrations using cold vapor atomic absorption spectrometry. We found that soil and house dust were the primary reservoirs of these elements. Diet contributed most strongly to the daily intake of these elements, with mean values of 0.72, 0.25, 0.054, 47, and 0.94 μg/kg/day for Hg, Cd, Pb, Mn, and Se, respectively. The mean hazard quotient of Hg was 1.53, indicating a high potential health risk from Hg exposure in daily lives. The intakes of other elements were below the tolerable limits. Future studies with a larger sample size are warranted to confirm our findings.

scholarly journals Contribution of Shellfish Consumption to Lower Mercury Health Risk for Residents in Northern Jiaozhou Bay, China

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Lei Zhang ◽  
Lei Zhang
Keyword(s):  
Health Risk ◽  
Lower Risk ◽  
Human Exposure ◽  
Hazard Quotient ◽  
Jiaozhou Bay ◽  
Daily Intake ◽  
Mercury Content ◽  
Target Hazard Quotient ◽  
Aquatic Products ◽  
Important Pathway

Fish and marine mammal consumption are an important pathway for human exposure to mercury. The low mercury content in shellfish poses a low mercury health risk to people who consume shellfish. The objectives of this study are to detect mercury concentrations in different species of shellfish and to calculate the mercury health risk from shellfish consumption among traditional residents near northern Jiaozhou Bay. A total of 356 shellfish samples, which comprised 7 species from 5 different places in northern Jiaozhou Bay, were collected from April to June in 2012. The average mercury content in the collected shellfish ranged from 0.024 mg·kg−1to 0.452 mg·kg−1. A total of 44 shellfish samples (12.36%) had mercury levels exceeding the national pollution-free aquatic products limit (0.3 mg·kg−1). Generally, the viscus had the highest mercury content among all parts of the shellfish. A positive correlation between mercury content and total weight/edible part weight was found in most species of the collected shellfish. The results showed that shellfish consumption resulted in the lower risk of mercury exposure to residents based on the calculation of daily intake (DI) and target hazard quotient (THQ).

scholarly journals Safety Evaluation of Potential Toxic Metals Exposure from Street Foods Consumed in Mid-West Nigeria

2017 ◽  
Vol 2017 ◽  
pp. 1-8 ◽  
Author(s):  
O. C. Ekhator ◽  
N. A. Udowelle ◽  
S. Igbiri ◽  
R. N. Asomugha ◽  
Z. N. Igweze ◽  
...  
Keyword(s):  
Health Risk ◽  
Toxic Metals ◽  
Hazard Quotient ◽  
Daily Intake ◽  
Hazard Index ◽  
Toxic Metal ◽  
Health Concern ◽  
Risk Level ◽  
Potential Health ◽  
Street Food

Objective. Street-vended foods offer numerous advantages to food security; nevertheless, the safety of street food should be considered. This study has investigated the level of potential toxic metal (Pb, Cd, Hg, Sb, Mn, and Al) contamination among street-vended foods in Benin City and Umunede. Methods. Twenty street food samples were purchased from vendors at bus stops. Metals were analyzed with atomic absorption spectrophotometry. The methods developed by the US EPA were employed to evaluate the potential health risk of toxic metals. Results. The concentrations of the toxic metals in mg/kg were in the range of Pb (0.014–1.37), Cd (0.00–0.00017), Hg (0.00–0.00014), Sb (0.00–0.021), Mn (0.00–0.012), and Al (0.00–0.22). All the toxic metals except Pb were below permissible limit set by WHO, EU, and USEPA. The daily intake, hazard quotient, and hazard index of all toxic metals except for Pb in some street foods were below the tolerable daily intake and threshold value of 1, indicating an insignificant health risk. Total cancer risk was within the priority risk level of 1.0E-04 but higher than the acceptable risk level of 1E-06. Conclusion. Consumption of some of these street foods is of public health concern.

scholarly journals Human Health Risk Assessment of Consuming Heavy Metals in Oyster (Crassostrea virginica) from Different Markets in Port Harcourt, Rivers State

2020 ◽  
Vol 3 (2) ◽  
Keyword(s):  
Health Risk ◽  
Human Health ◽  
Human Health Risk ◽  
Daily Intake ◽  
Hazard Index ◽  
Pollution Levels ◽  
Niger Delta Region ◽  
The People ◽  
Port Harcourt ◽  
Rivers State

Food safety is of great concern in the Niger Delta region of Nigeria because of its pollution levels. Shell fish is one of the major diets of the people of Rivers State and they affect a large market and customer target in the region. This study was aimed at assessing the human health risk from consuming oysters bought from different markets in Rivers State namely; Creek Road market Borokiri, Mile 3 Market and Choba Market while Oysters harvested from ARAC (Buguma) were used as control. Lead (Pb), Cadmium (Cd), Chromium (Cr), Cobalt (Co) and Nickel (Ni) were analysed in all samples using the Atomic absorption spectrometer. Cobalt had the highest concentration in all the samples from the markets except Mile 3 market, it ranged from 0.011-0.014mg/kg, while Lead ranged from 0.007-0.012 mg/kg, Chromium ranged from 0.008-0.010 mg/kg, Nickel ranged from 0.008-0.021 mg/kg and Cadmium ranged from 0.001-0.007mg/kg .The Estimated Daily Intake (EDI) of these metals were calculated, Target Human Quotient (THQ) and Hazard Index (HI) derived. EDI values were within tolerable limit. THQ and HI calculated indicated likely risk from oyster consumption since the values obtained were above the threshold of one (1) for lead, Cobalt and Cadmium, long term consumption may lead to health risk.

scholarly journals Exposure Assessment of Total Mercury: A Probabilistic-Approach Study Based on Consumption of Canned Fish

2019 ◽  
Author(s):  
Afshin Ebrahimi ◽  
Elaheh Karimpoor ◽  
Zahra Godazandehha ◽  
Zahra Heidari ◽  
Maryam Zarean ◽  
...  
Keyword(s):  
Health Risk ◽  
Fish Consumption ◽  
Hazard Quotient ◽  
Probabilistic Method ◽  
Probabilistic Approach ◽  
Daily Intake ◽  
Vulnerable Groups ◽  
Health Concern ◽  
Potential Health ◽  
Canned Fish

Introduction: Exposure to mercury (Hg) by consumption of fish is a recent health concern. So, it is important to evaluate the health risks related to canned fish consumption. The purpose of this study was to investigate the potential health risk based on Hg concentration in people who consumed canned fish with a probabilistic approach in Isfahan City, the central province in Iran. Materials and Methods: In this study, 20 popular brands of canned fish prepared in Iran and other countries were selected and analyzed for Hg concentration with atomic absorption spectrometer. The results were compared with the European Communities and JECFA guidelines. Then, a probabilistic method with Monte-Carlo simulation was used to assessment the Provisional Tolerable Daily Intake (PTDI) and the Hazard Quotient (HQ) for consumers in Isfahan City. Results: The average Hg concentrations in samples were 0.251 ± 0.204 and 0.189 ± 0.152 µg/g in canned fish of Iran and other countries, respectively. The Hg level was found below the guideline limit for European Communities and JECFA. The estimated PTDI was 0.037 µg person/day and HQ was 0.074. Conclusion: The results indicated that canned fish available in the markets of Iran did not have a health risk for adults. Moreover, canned fish consumption has a possible influence on the risk estimate and its risk should be assessed  for vulnerable groups.

scholarly journals Consumption Safety in Relation to Bioaccumulation of Heavy Metals in Periwinkles (Tympanotonus fuscatus) Obtained from Ogbia in the Niger Delta Region of Nigeria

2020 ◽  
Author(s):  
Miebaka Moslen ◽  
Chioma Hope Adiela
Keyword(s):  
Heavy Metals ◽  
Health Risk ◽  
Niger Delta ◽  
Hazard Quotient ◽  
Human Health Risk ◽  
Daily Intake ◽  
Temporal Variations ◽  
Delta Region ◽  
Niger Delta Region ◽  
Accumulation Of Metals

The study assessed human health risk and accumulation of heavy metals (Cd, Cu, Pb, Ni, Cr and Zn) in periwinkles (Tympanotonus fuscatus) obtained from the Niger Delta region of Nigeria. Samples were collected for six months on a monthly basis. The samples were digested according to the method described by Association of official analytical chemists and analyzed using atomic absorption spectrophotometer (AAS). Temporal variations in metal concentrations were observed with values (mgkg−1) ranging as follows Pb (2.34–6.7), Ni (0.55–2.28), Zn (0.55–11.66), Cr (0.74–3.65), Cu (1.15–3.91) and Cd (0.22–1.06). Variation in metal concentration was significantly different (p < 0.05) with metals such as Pb, Ni and Cd found to be above their respective FAO/WHO permissible limits. The estimated daily intake (EDI) of all metals examined was less than their respective reference oral doses (RFD). The target hazard quotient (THQ) non-carcinogenic and the hazard index (HI) of metals were < 1 while the hazard quotient carcinogenic (HQ) ranged between 10−6 – 10−4. The study therefore concluded gradual accumulation of metals and minimal health risk due to consumption of contaminated periwinkles in the study area.

scholarly journals Health Risk Assessment for Carcinogenic and Non Carcinogenic Heavy Metal Exposure from Hibiscus Leaf Cultivated in Katsina State, North West Nigeria

2019 ◽  
pp. 1-12
Author(s):  
A. I. Yaradua ◽  
A. J. Alhassan ◽  
A. Nasir ◽  
K. I. Matazu ◽  
A. Usman ◽  
...  
Keyword(s):  
Heavy Metals ◽  
Cancer Risk ◽  
Health Risk ◽  
Hazard Quotient ◽  
Daily Intake ◽  
Health Concern ◽  
Risk Level ◽  
Target Hazard Quotient ◽  
Moderate Risk ◽  
Mean Concentration

This study was conducted to determine the heavy metals concentration in Hibiscus leaves cultivated in Katsina State Nigeria. The objectives were mainly to detect the presence of heavy metals in the cultivated Hibiscus leaves in the study area, compare the concentration of heavy metals in samples in relation to the permissible limits specified by WHO/FAO/USEPA Standards. Samples of cultivated Hibiscus leaves were collected in the year 2017 from the selected area.  Analysis for the concentration of these heavy metals; Cr, Cd, Fe, Ni, Mn, Pb and Zn was conducted by the use of AAS (by Atomic Absorption Spectrophotometry) method. The health risks to the local inhabitants from the consumption of the samples were evaluated based on the Target Hazard Quotient (THQ). The possibility of cancer risks for the adult and children population through intake of carcinogenic heavy metals in the samples was estimated using the Incremental Lifetime Cancer Risk (ILCR). Results from this study shows that with the exception of Pb with mean concentration of (0.508-0.978), the mean concentration (mg/kg) range values of Cr (0.135-0.261), Cd (0.042-0.051), Fe (0.684-0.978) and Zn (1.048-1.208) in the samples were generally lower than the USEPA, WHO/FAO maximum permissive limits. The results have indicated that the estimated daily intake (EDI) of the heavy metals were lower than the tolerable daily intake limit set by the USEPA in both samples and the health risk index (HRI) for all the heavy metals were <1. The target hazard quotient (THQ) for the samples for both the adult and children population was in the decreasing order of Zn>Pb>Fe>Cr>Cd. ILCR for Cd is below the threshold risk limit (>10−5) and ILCR for Pb reached the moderate risk limit (>10−3) in all the studied samples in adults, While in children ILCR for both Pb and Cd in samples from Dabai, Daura, Funtua, Matazu and Zango for all samples have reached the moderate risk limit (>10−3), while the ILCR for Pb in samples from Birchi, Dutsinma, Kafur, Katsina and Malunfashi were beyond the moderate risk level (>10−2). The sampling area trend of risk for developing cancer as a result of consuming the studied samples showed: Funtua > Daura > Dutsinma > Katsina > Malunfashi > Matazu > Zango > Ingawa > Kafur > Dabai > Birchi for both adult and children, cumulative cancer risk (∑ILCR) of all the studied Hibiscus samples have reached the moderate risk limit (>10−3) in adult. While in children with the exception of the sample from Birchi, Dabai and Kafur which are within the moderate cancer risk (>10−3) limit, all other samples were beyond the moderate cancer risk (>10−2) limit. The study suggests that consumption of the studied samples in Katsina state is of public health concern as they may contribute to the population cancer burden. 

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