scholarly journals Tuberculosis-Candida Co-Infection in Patients having Pulmonary Tuberculosis Attending DOTs Clinic in Rumuigbo Model Primary Health Centre in Port Harcourt, Nigeria

2019 ◽  
pp. 1-7
Author(s):  
Asikiya Hanson ◽  
Amala Smart Enoch ◽  
Gloria N. Wokem
Keyword(s):  
Pulmonary Tuberculosis ◽  
Health Centre ◽  
Staining Technique ◽  
Tuberculosis Patients ◽  
Candida Sp ◽  
Tube Test ◽  
Predominant Species ◽  
Sugar Fermentation ◽  
Primary Health ◽  
Port Harcourt

Introduction: Some pulmonary tuberculosis subjects were some co-infected with Candida such as C. albicans, C. tropicalis, C. kruezi and C. paraspsilosis which were initially thought to be normal floras of the oral cavity. The percentage of tuberculosis patients co-infected with Candida is becoming a concern and might complicate the treatment of tuberculosis. Materials and Methods: A total of 400 sputum samples were collected and subjected to Ziehl-Neelsen staining technique and Genexpert system, Gram’s stain, Germ tube test and examination in KOH preparation were conducted. Culture on Sabouraud Dextrose Agar with gentamicin, and cultured on CHROMagar Candida and sugar fermentation were carried out for Candida. Results: Out of the 400 sputum samples examined 93(23.3%) had TB and 32(8.0%) were positive for Candida. By gender the prevalence of tuberculosis were females 51(22.4%), males 42(24.4%) while the prevalence of Candida were females 18(35.3%) and males 14(33.3%). The percentage occurrences of Candida sp. isolated were C. albicans which was the predominant species 10(21.5%), C. tropicals 5(5.4%), C. krusei 4(4.3%) and C. Parapsilosis 3(3.2%) respectively. Conclusion: Candida albicans remains the most predominant species of Candida in patients suffering from pulmonary tuberculosis and colonization by Candida sp should not be ignored. The presence of Candida sp. might contribute to in one way to the progression of the disease.

scholarly journals Growth of Candida sp and Aspergillus sp from Bronchoscopy Pulmonary Tuberculosis Patients on Bran Media

2018 ◽  
Vol 9 (2) ◽  
Author(s):  
Mujahidah Basarang ◽  
Muhammad Rifo Rianto
Keyword(s):  
Pulmonary Tuberculosis ◽  
Fungal Growth ◽  
Raw Material ◽  
Growth Media ◽  
Carbohydrate Source ◽  
Tuberculosis Patients ◽  
Culture Techniques ◽  
Candida Sp ◽  
Untreated Culture ◽  
Aspergillus Sp

Pulmonary tuberculosis caused by Mycobacterium tuberculosis become ahealth problem in Indonesia. The chronic nature of this disease is further exacerbated ifit is accompanied by fungal infection such as Candida albicans and Aspergillus sp.,which is usually remains undiagnosed and thus untreated. Culture techniques can beused to identify Candida sp and Aspergillus sp from bronchoscopy. Fungal culturemedia in laboratory containing high carbohydrate source, nitrogen source are requiredfor the growth. This nutrient can be found in bran that contains high carbohydrates,proteins, fats, vitamins, and crude fiber. So that bran can be used as raw material for alternative fungal growth media. The purpose of this study was to increase bran as amedium for the growth of Candida sp and Aspergillus sp isolated from bronchoscopy ofpulmonary TB patients. This study included bran collection, preparation of bran media,inoculation bronchoscopy on bran media, observation of fungal growth. Colonies ofCandida sp and Aspergillus sp were confirmed microscopically. The results showed thatCandida sp and Aspergillus sp grew on both media, Bekatul Dextrose Agar and PotatoDextrose Agar. The conclusion of this study is that bran can be used as a medium forfungal growth. Bran media can be used as an alternative media to replace syntheticmedia to grow Candida sp and Aspergillus sp isolated from bronchial rinses.

scholarly journals Gender Difference on Case Detection of Pulmonary Tuberculosis Among the Suspected Cases Attending in Jutpani Primary Health Centre of Chitwan, Nepal

2013 ◽  
Vol 10 (1) ◽  
pp. 7-12
Author(s):  
K Amgain ◽  
Dillee Prasad Paudel ◽  
DP Paneru ◽  
M Dhital ◽  
G Amgain
Keyword(s):  
Gender Difference ◽  
Pulmonary Tuberculosis ◽  
Health Centre ◽  
Preventive Measure ◽  
Clinical History ◽  
Cross Sectional Study ◽  
Narrative Form ◽  
Cross Sectional ◽  
Female Ratio ◽  
Primary Health

Introduction: Pulmonary tuberculosis is one of the World’s public health problems particularly in developing countries including Nepal. Every year, thousands of people suffered from active tuberculosis in Nepal; of whom 50 percent have infectious pulmonary tuberculosis. It is more common among men than women, and affects mostly adults of economically productive age. There is scantiness of such information in Nepal. Hence the study was carried out to identify the gender difference on case identifi cation of pulmonary tuberculosis in Chitwan district of Nepal. Methodology: Descriptive cross sectional study was carried out from July to December 2012 in Jutpani Village Development Committee of Chitwan, Nepal. All symptomatic cases attending in Jutpani Primary Health Center with the clinical history pulmonary tuberculosis were included. Microscopic examination of sputum samples of three consecutive days was done for AFB. Results were disseminated in tabular, graphical and narrative form using appropriate statistics. Results: Total 200 suspected cases of pulmonary tuberculosis were included in this study; among them 18 (9%) were found to be AFB positive. Sex ratio of diagnosed patients was 5:4 (male; 55.56% and female; 44.44%). Highest prevalence of TB infection (36.89%) was found in 30-40 years age. Highest number of cases 5 (27.78%) were reported in the ward number four (male female ratio; 3:2). One-third of cases were in July followed by 22.22% in each of the month; August and September. Conclusion: Males were found to be more likely to have pulmonary tuberculosis than females. Gender specifi c case identifi cation and preventive measure targeting to the most productive age group population will eventually supports to reduce the risk of pulmonary tuberculosis. SAARC Journal of Tuberculosis, Lung Diseases & HIV/AIDS; 2013; X(1); 7-12 DOI: http://dx.doi.org/10.3126/saarctb.v10i1.8644

scholarly journals The Impact of Environmental Health Services in Primary Health Care on Improving the Behavior of Pulmonary Tuberculosis Patients in Banyuwangi Regency

2020 ◽  
Vol 12 (3) ◽  
pp. 181
Author(s):  
Sheilla Mufidha Wahyuningtyas ◽  
Endang Sri Lestari ◽  
Jojok Mukono ◽  
Endro Sukmono
Keyword(s):  
Health Care ◽  
Primary Health Care ◽  
Health Services ◽  
Pulmonary Tuberculosis ◽  
Environmental Health ◽  
Tuberculosis Patients ◽  
Pulmonary Tb ◽  
Primary Health ◽  
Post Test ◽  
The Impact

Introduction: Tuberculosis (TB) is a global health crisis. Environmental health services in Primary health care provide counseling services, inspections and environmental health interventions. Research aims to determine the impact of environmental health services in Primary health care on the behavior of TB patients that includes the knowledge, attitudes and actions of pulmonary tuberculosis patients in the prevention of the transmission of pulmonary tuberculosis disease. Method: The method in this study was experimental quasi. Respondents were a new case of pulmonary TB at 6 Primary health care in Banyuwangi Regency April S/d June 2019. Pre test before obtaining environmental health services. Post test was given after counseling, inspection and environmental health intervention. Result and Discussion: The results showed a total of 24 respondents to the majority pulmonary tuberculosis patient was male (54.17%). Pre test knowledge of pulmonary TB patient is good (4.16%), enough (8.33%) and less (87.50%). Category Post test knowledge of TB patients acquired good (20.83%), sufficient category (75.00%) and less (4.20%). The average Pre test knowledge score is 37.70 and the Post test is 67.20. Category Prettest Action patients TB is good (4.16%) and less (95.83%). Category Post Test action patients pulmonary TB is good (54.17%), enough (41.67%) and less (4.16%) Which is an improvement in the form of masks, hand washing soap, the habit of spitting, the use of individual cutlery and drinking equipment, washing dinnerware and drinking with hot water/drying, drying the sleeping tools, opening a window every day, separate sleeping habits. Conclusion: The conclusion of this research is environmental health services in Primary health care in patients with pulmonary tuberculosis improves the behavior of TB patients in the form of increased knowledge, attitudes and actions of the patient in the prevention of disease transmission of TB.

scholarly journals Universal Access to Xpert MTB/RIF Testing for Diagnosis of Tuberculosis in Uzbekistan: How Well Are We Doing?

2021 ◽  
Vol 18 (6) ◽  
pp. 2915
Author(s):  
Laziz Turaev ◽  
Ajay Kumar ◽  
Dilyara Nabirova ◽  
Sevak Alaverdyan ◽  
Nargiza Parpieva ◽  
...  
Keyword(s):  
Universal Access ◽  
Health Centre ◽  
Multivariable Analysis ◽  
P Value ◽  
National Guidelines ◽  
Tuberculosis Patients ◽  
Factors Associated ◽  
Primary Health ◽  
Published Evidence ◽  
Diagnostic Capacity

As per national guidelines in Uzbekistan, all presumptive tuberculosis patients should be tested using the Xpert MTB/RIF assay for diagnosing tuberculosis. There is no published evidence how well this is being implemented. In this paper, we report on the Xpert coverage among presumptive tuberculosis patients in 2018 and 2019, factors associated with non-testing and delays involved. Analysis of national aggregate data indicated that Xpert testing increased from 24% in 2018 to 46% in 2019, with variation among the regions: 21% in Tashkent region to 100% in Karakalpakstan. In a cohort (January–March 2019) constituted of 40 randomly selected health facilities in Tashkent city and Bukhara region, there were 1940 patients of whom 832 (43%, 95% confidence interval (CI): 41–45%) were not Xpert-tested. Non-testing was significantly higher in Bukhara region (73%) compared to Tashkent city (28%). In multivariable analysis, patient’s age, distance between primary health centre (PHC) and Xpert laboratory, diagnostic capacity and site of PHC were associated with non-testing. The median (interquartile range) duration from date of initial visit to PHC to receiving results was 1 (1–2) day in Tashkent city compared to 3 (1–6) days in Bukhara region (p-value < 0.001). While there is commendable progress, universal access to Xpert testing is not a reality yet.

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