Age and Gender Differences in the Pattern of Antiplatelet Agents Prescribing

Aim: There is a scarcity of data regarding gender and age related aspects of antiplatelet drugs utilization in the outpatient setting. Thus, the objective of the present study was to determine the age-and gender-related differences in the outpatient use of antiplatelet drugs in Alkharj. Methodology: This is a retrospective study that include the assessment of electronic prescriptions in the outpatient setting that include an antiplatelet drug in 2018. Results: Ticagrelor was prescribed mainly for patients more than 60 years old (84.62%). Clopidogrel was prescribed mainly for patients more than 50 years old (79.76%) and aspirin also was prescribed mainly for patients more than 50 years old (71.67%). Generally, most of the patients who received antiplatelet agents were male (52.76%). Conclusion: The present study showed that there were differences in prescribing antiplatelet agents between different gender and different ages. So it is important to know the prescribing trends and to give the appropriate drugs based on several factors such as gender and age. It is expected that in the future, antiplatelet therapy may be based on age and on endogenous sex hormone level or genetic female/male differences.

Age and Gender Differences in the Variability of Vocational Interests

Journal of Career Assessment ◽

10.1177/1069072717748646 ◽

2017 ◽

Vol 27 (1) ◽

pp. 97-113 ◽

Cited By ~ 1

Author(s):

Andrei Ion ◽

Christopher D. Nye ◽

Dragoş Iliescu

Keyword(s):

Gender Differences ◽

Early Adolescence ◽

Early Adulthood ◽

Age Groups ◽

Vocational Interests ◽

Age And Gender ◽

Age Related ◽

Gender And Age ◽

Gender- and age-related differences in the variability of various human attributes and abilities have been investigated. This article investigates the age and gender differences in the variability of Holland’s six vocational dimensions with a sample including 1,519 participants, divided into four age groups: early adolescence (12–15 years old), adolescence (16–20 years old), young adulthood (21–30 years old), and adulthood (31–59 years old). The results showed nontrivial differences in the variability of vocational interests across gender and age groups alike. Although significant differences in variability were observed for all vocational interest dimensions except investigative, the most pronounced differences in variability across age and gender were observed for realistic and conventional dimensions. Generally, the observed differences in variability were larger in adolescence than in adulthood. Overall, vocational interests displayed less differentiation within the younger age groups (early adolescence and early adulthood) as compared to adulthood.

Age and Gender Trends in Prescribing and Utilization of Lipid-Lowering Drugs at a Public Hospital in Alkharj City

Journal of Pharmaceutical Research International ◽

10.9734/jpri/2020/v32i2730848 ◽

2020 ◽

pp. 1-5

Author(s):

Nehad J. Ahmed ◽

Menshawy A. Menshawy ◽

Ziyad S. Almalki ◽

Mohammed A. Alhajri

Keyword(s):

Public Hospital ◽

Outpatient Setting ◽

Lipid Lowering ◽

Prescribing Pattern ◽

Cross Sectional ◽

Age And Gender ◽

Lipid Lowering Drugs ◽

Age Related ◽

Gender And Age ◽

Aim: Lipid-lowering drugs are used to decrease low-density lipoprotein cholesterol and as a result, they are used in both secondary and primary prevention of cardiovascular diseases. This study aimed to observe the prescribing trend of lipid-lowering drugs and to describe the gender and age-related differences in the outpatient setting of a public hospital in Alkharj city. Methodology: This is a cross-sectional observational study that was conducted in outpatient setting of a public hospital in Alkharj city and included the review of electronic outpatient prescriptions. The data was collected and analyzed using Excel software; the descriptive data were represented by percentages and numbers. Results: The most prescribed lipid-lowering drug in the present study was atorvastatin (62.36%) followed by simvastatin (29.34%). The study found that there are several differences in lipid lowering medications use patterns among different gender and age groups. Therefore, frequent reviews of lipid-lowering drugs use and prescribing pattern are important to optimize patients’ treatment. Conclusion: It is important in the future to make stratified guidelines based on patient characteristics such as age and gender.

Age and Gender Differences in Self-Esteem—A Cross-Cultural Window

10.31219/osf.io/b65sa ◽

2017 ◽

Author(s):

Wiebke Bleidorn ◽

Ruben C. Arslan ◽

Jaap J. A. Denissen ◽

Jason Rentfrow ◽

Jochen E. Gebauer ◽

...

Keyword(s):

Age Differences ◽

The United States ◽

Self Esteem ◽

Cross Cultural ◽

Age And Gender ◽

Empirical Base ◽

Age Related ◽

Gender And Age ◽

Gender And Age Differences ◽

Research and theorizing on gender and age differences in self-esteem have played a prominent role in psychology over the past 20 years. However, virtually all empirical research has been undertaken in the United States or other Western industrialized countries, providing a narrow empirical base from which to draw conclusions and develop theory. To broaden the empirical base, the present research uses a large Internet sample (N 985,937) to provide the first large-scale systematic cross-cultural examination of gender and age differences in self-esteem. Across 48 nations, and consistent with previous research, wefound age-related increases in self-esteem from late adolescence to middle adulthood and significant gender gaps, with males consistently reporting higher self-esteem than females. Despite these broad cross-cultural similarities, the cultures differed significantly in the magnitude of gender, age, and Gender Age effects on self-esteem. These differences were associated with cultural differences in socioeconomic, sociodemographic, gender-equality, and cultural value indicators. Discussion focuses on the theoretical implications of cross-cultural research on self-esteem.

Exploiting Molecular Basis of Age and Gender Differences in Outcomes of SARS-CoV-2 Infections.

10.1101/2021.05.23.21257669 ◽

2021 ◽

Author(s):

Daniele Mercatelli ◽

Elisabetta Pedace ◽

Federico Manuel Giorgi ◽

Pietro Hiram Guzzi

Keyword(s):

Molecular Mechanisms ◽

Molecular Level ◽

Tissue Level ◽

Adverse Outcomes ◽

Aging Effects ◽

Age And Gender ◽

Gender And Age ◽

And Gender ◽

Public Datasets

Motivation: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (coronavirus disease, 2019; COVID-19) is associated with adverse outcomes in patients. It has been observed that lethality seems to be related to the age of patients. Moreover, it has been demonstrated that ageing causes some modifications at a molecular level. Objective: The study aims to shed out light on a possible link between the increased COVID-19 lethality and the molecular changes that occur in elderly people. Methods: We considered public datasets on ageing-related genes and their expression at tissue level. We selected interactors that are known to be related to ageing process. Then, we performed a networkbased analysis to identify interactors significantly related to both SARS-CoV-2 and ageing. Finally, we investigated changes on the expression level of coding genes at tissue, gender and age level. Results We observed a significant intersection between some SARS-CoV-2 interactors and ageing-related genes suggesting that those genes are particularly affected by COVID-19 infection. Our analysis evidenced that virus infection particularly affects ageing molecular mechanisms centred around proteins EEF2, NPM1, HMGA1, HMGA2, APEX1, CHEK1, PRKDC, and GPX4. We found that HMGA1, and NPM1 have a different expression in lung of males, while HMGA1, APEX1, CHEK1, EEF2, and NPM1 present changes in expression in males due to aging effects. Conclusion Our study generated a mechanistic framework to explaining the correlation between COVID-19 incidence in elderly patients and molecular mechanisms of ageing. This will provide testable hypotheses for future investigation and pharmacological solutions tailored on specific age ranges.

Age and gender comparisons of muscle strength in 654 women and men aged 20–93 yr

Journal of Applied Physiology ◽

10.1152/jappl.1997.83.5.1581 ◽

1997 ◽

Vol 83 (5) ◽

pp. 1581-1587 ◽

Cited By ~ 532

Author(s):

R. S. Lindle ◽

E. J. Metter ◽

N. A. Lynch ◽

J. L. Fleg ◽

J. L. Fozard ◽

...

Keyword(s):

Gender Differences ◽

Muscle Strength ◽

Peak Torque ◽

Muscle Quality ◽

Age And Gender ◽

Men And Women ◽

Age Related ◽

Stretch Shortening Cycle ◽

Lindle, R. S., E. J. Metter, N. A. Lynch, J. L. Fleg, J. L. Fozard, J. Tobin, T. A. Roy, and B. F. Hurley. Age and gender comparisons of muscle strength in 654 women and men aged 20–93 yr. J. Appl. Physiol. 83(5): 1581–1587, 1997.—To assess age and gender differences in muscle strength, isometric, concentric (Con), and eccentric (Ecc) peak torque was measured in the knee extensors at a slow (0.52 rad/s) and fast (3.14 rad/s) velocity in 654 subjects (346 men and 308 women, aged 20–93 yr) from the Baltimore Longitudinal Study of Aging. Regression analysis revealed significant ( P < 0.001) age-related reductions in Con and Ecc peak torque for men and women at both velocities, but no differences were observed between the gender groups or velocities. Age explained losses in Con better than Ecc peak torque, accounting for 30% (Con) vs. 19% (Ecc) of the variance in men and 28% (Con) vs. 11% (Ecc) in women. To assess age and gender differences in the ability to store and utilize elastic energy, the stretch-shortening cycle was determined in a subset of subjects ( n = 47). The older women (mean age = 70 yr) showed a significantly greater enhancement in the stretch-shortening cycle, compared with men of similar age ( P < 0.01) and compared with younger men and women (each P < 0.05). Both men and women showed significant declines in muscle quality for Con peak torque ( P < 0.01), but no gender differences were observed. Only the men showed a significant decline in muscle quality ( P < 0.001) for Ecc peak torque. Thus both men and women experience age-related losses in isometric, Con, and Ecc knee extensor peak torque; however, age accounted for less of the variance in Ecc peak torque in women, and women tend to better preserve muscle quality with age for Ecc peak torque. In addition, older women have an enhanced capacity to store and utilize elastic energy compared with similarly aged men as well as with younger women and men.

Scientific Journal of National Pedagogical Dragomanov University. Series 15. Scientific and pedagogical problems of physical culture (physical culture and sports) ◽

Age-related characteristics of the reaction of the cardiovascular system of young swimmers to dosed physical activity

10.31392/npu-nc.series15.2020.3(123).32 ◽

2020 ◽

pp. 172-176

Author(s):

A. Yushko ◽

N. Balamutova ◽

E. Bloshenko ◽

L. Sheyko

Keyword(s):

Physical Activity ◽

Cardiovascular System ◽

Bicycle Ergometer ◽

School Age Children ◽

System Response ◽

School Age ◽

Age And Gender ◽

Age Related ◽

In the age-related pedagogy and physiology one of important questions is the study of the influence of physical activities on the state of the cardiovascular system of children and teenagers. The reactions of the cardiovascular system in response to physical activity have significant age and gender differences. In this regard, the indicators of the cardiovascular system were analyzed when working on a bicycle ergometer in schoolchildren before, during, at the time of completion of puberty. The aim of this research was to study the age-related characteristics of the testes` cardiovascular system response to dosed physical activity. The revealed regularities of the reaction of the cardiovascular system of school-age children to physical activity can serve as a criterion for assessing their functional possibilities.