scholarly journals Role of Green Tea on Obesity and Type-II Diabetes Mellitus Male Individuals

2021 ◽  
pp. 183-187
Author(s):  
Tazeen Shah ◽  
Saira Dars ◽  
Saima Ashfaque Sheikh ◽  
Farheen Shaikh ◽  
Shafaq Ansari ◽  
...  
Keyword(s):  
Green Tea ◽  
Total Body Weight ◽  
Type Ii Diabetes Mellitus ◽  
Serum Glucose ◽  
The Body ◽  
Research Centre ◽  
P Value ◽  
Glucose Levels ◽  
Total Body

Objective: To evaluate the effects of Green tea on obesity and hyperglycemia. Methodology: This observational study was carried out at the department of physiology, in affiliation to Medical Research Centre Liaquat University of Medical and Health Sciences Jamshoro. The sample was collected by convenient random sampling. Total 100 participants, 50 controls and 50 obese diabetics were enrolled. Informed written consent was taken from participants. The body mass index (BMI) of the participants was taken at the time of recruitment, and later at 16 weeks of consuming green tea. The serum glucose levels were assessed by fasting (FBS) and random blood sugar (RBS) levels, and HbA1C. The levels of serum Blood glucose were obtained with the glucose oxidase method. Data analysis was done on SPSS 21.0, analysis of variables was done by applying student t-test, the p-value of <0.05 was taken as statistically significant. Results:100 participants recruited out of which 50 controls and 50 obese diabetics men, it was found that the prolong consumption of green tea for 16 weeks with 20-30 minutes’ walk had statistically significant declined in FBS, RBS, HbA1c, and BMI in the obese diabetic subjects, as compared to the controls. Conclusion: This study concludes that the green tea has positive effect in reducing the total body weight and BMI and helps in maintaining the normoglycemic levels in Type 2 DM.

Comparative Impact of Isolated Ultrafiltration and Hemodialysis on Fluid Distribution: A Bioimpedance Study

2021 ◽  
pp. 1-11
Author(s):  
Yuki Akiyama ◽  
Ryo Matsuoka ◽  
Takahiro Masuda ◽  
Sumiya Iwamoto ◽  
Shun Sugie ◽  
...  
Keyword(s):  
Reduction Rate ◽  
Extracellular Fluid ◽  
Serum Glucose ◽  
The Body ◽  
Fluid Distribution ◽  
Glucose Levels ◽  
Reduction Effect ◽  
Total Body ◽  
The Impact ◽  
Osmolal Gap

<b><i>Introduction:</i></b> Isolated ultrafiltration (IUF) is an alternative treatment for diuretic-resistant patients with fluid retention. Although hemodialysis (HD) predominantly decreases extracellular water (ECW), the impact of IUF on fluid distribution compared with HD remains unclear. <b><i>Methods:</i></b> We compared the effect of HD (<i>n</i> = 22) and IUF (<i>n</i> = 10) sessions on the body fluid status using a bioimpedance analysis device (InBody S10). <b><i>Results:</i></b> The total ultrafiltration volume was similar between HD and IUF (HD 2.5 ± 0.3 vs. ICF 2.1 ± 0.3 L/session, <i>p</i> = 0.196). The reduction rate of ECW was significantly higher than that of intracellular water (ICW) after HD (ECW −7.9% ± 0.8% vs. ICW −3.0% ± 0.9%, <i>p</i> &#x3c; 0.001) and IUF (ECW −5.8% ± 0.9% vs. ICW -3.6% ± 0.8%, <i>p</i> = 0.048). However, the change in the ratio of ECW to total body water in HD was significantly larger than that in IUF (HD −3.2% ± 0.3% vs. ICF −1.1% ± 0.4%, <i>p</i> &#x3c; 0.001). The reduction rates in serum tonicity (effective osmolality) were higher after HD than after IUF (HD −1.8% ± 0.5% vs. IUF −0.6% ± 0.2%, <i>p</i> = 0.052). Among the components of effective osmolality, the reduction rates of serum K<sup>+</sup> and glucose levels after HD were significantly higher than those after IUF (serum K<sup>+</sup>: HD −30.5% ± 1.6% vs. IUF −0.5% ± 3.8%, <i>p</i> &#x3c; 0.001; serum glucose: HD −15.4% ± 5.0% vs. IUF 0.7% ± 4.8%, <i>p</i> = 0.026), while the serum Na<sup>+</sup> level was slightly and similarly reduced (HD −0.8% ± 0.4% vs. IUF −0.8% ± 0.4%, <i>p</i> = 0.500). The reduction in the osmolal gap value (measured osmolality–calculated osmolarity) was significantly greater after HD sessions than after IUF sessions (HD −12.4 ± 1.4 vs. IUF 2.0 ± 1.0 mOsm/kg, <i>p</i> = 0.001). <b><i>Conclusion:</i></b> The extracellular fluid reduction effect of HD is stronger than that of IUF. The different changes in effective osmolality and osmolal gap after HD and IUF sessions may be related to the different effects of HD and IUF on fluid distribution.

The role of liraglutide in the management of obesity

2019 ◽  
Vol 8 (7) ◽  
pp. 322-326
Author(s):  
Gemma Fromage
Keyword(s):  
Mental Health ◽  
Physical Activity ◽  
Total Body Weight ◽  
The Body ◽  
European Medicines Agency ◽  
Calorie Diet ◽  
Total Body ◽  
The Uk

Obesity has been defined as abnormal or excessive fat accumulation that may impair health. Obesity is associated with multiple comorbidities, affecting mechanical systems within the body as well as metabolic and mental health. If a person is overweight or obese, a loss of 5–10% of total body weight can have a number of health advantages. In the UK, there are three medications approved by the European Medicines Agency (EMA) for weight loss: orlistat, liraglutide and naltrexone in combination with bupropion. Liraglutide has the proprietary name Saxenda (Novo Nordisk). It may be prescribed for individuals with a body mass index (BMI) of 30 kg/m2 or more or people with a BMI of 27 kg/m2 who have another weight-related illness, such as high blood pressure, type 2 diabetes or dyslipidaemia. As with many weight-management programmes, liraglutide works in conjunction with a reduced-calorie diet and increased physical activity.

The putative effects of green tea on body fat: an evaluation of the evidence and a review of the potential mechanisms

2011 ◽  
Vol 106 (9) ◽  
pp. 1297-1309 ◽  
Author(s):  
Navamayooran Thavanesan
Keyword(s):  
Weight Loss ◽  
Green Tea ◽  
Body Fat ◽  
Fatty Acid Synthase ◽  
The Body ◽  
Alternative Methods ◽  
Future Research ◽  
Prevalence Of Obesity ◽  
Simultaneous Inhibition

The increase in the prevalence of obesity in recent years has prompted research into alternative methods of modulating body weight and body fat. The last decade has reflected this with a surge in studies investigating the potential of green tea as a natural agent of weight loss, with a view to confirming and elucidating the mechanisms underlying its effect on the body. Currently, it is widely believed that the polyphenolic components present in green tea have an anti-obesogenic effect on fat homeostasis, by increasing thermogenesis or reducing fat absorption among other ways. The data published to date, however, are inconsistent, with numerous putative modes of action suggested therein. While several unimodal mechanisms have been postulated, a more plausible explanation of the observed results might involve a multimodal approach. Such a mechanism is suggested here, involving simultaneous inhibition of the enzymes catechol-O-methyltransferase, acetyl-CoA carboxylase, fatty acid synthase and impeding absorption of fat via the gut. An evaluation of the available evidence supports a role of green tea in weight loss; however the extent of the effects obtained is still subject to debate, and requires more objective quantification in future research.

scholarly journals Role of Vitamin D in Reducing the Frequency of Asthma Attacks in Patients with Frequent Exacerbation of Asthma

2021 ◽  
pp. 11-16
Author(s):  
Mubeen Ahmed Memon ◽  
Sheeba Faryal Ansari ◽  
Mumtaz Ali Lakho ◽  
Mukhtiar Hussain Jaffery ◽  
Syed Zulfiquar Ali Shah ◽  
...  
Keyword(s):  
Vitamin D ◽  
Corticosteroid Treatment ◽  
Vitamin D Supplementation ◽  
The Body ◽  
P Value ◽  
Care Hospital ◽  
Asthma Exacerbations ◽  
Vitamin D Levels ◽  
Interventional Group

Introduction: Vitamin D deficiency is common among asthmatics with literature suggesting that its low levels in the body may trigger exacerbations and decrease the response to corticosteroid treatment. It has also shown to inhibit the production of cytokines, which in turn enhances the body’s response to corticosteroid treatment during an exacerbation. Therefore, maintenance of adequate levels of vitamin D in patients with asthma may reduce the risk of exacerbation and improve their general health. This study aims to explore the role of vitamin D supplementation in preventing asthma exacerbations. Methods: This single blind parallel arm interventional study was conducted in the pulmonology ward in a tertiary care hospital from June 2018 to April 2020. Two hundred (n= 200) participants with a history of frequent acute exacerbation of asthma were enrolled in the study via consecutive convenient non-probability technique. Participants were divided into two groups; the placebo and the interventional group that received 200,000 IU of vitamin D capsule. Results: Compared to day 0, mean episodes of exacerbation in the interventional group were significantly lower after 180 days (1.1 ± 0.4 vs. 0.61 ± 0.3; p-value <0.0001). Similarly, number of asthma attacks in past 7 days was significantly lower in intervention group after 180 days (4.4 ± 2.7 vs. 3.1 ± 1.5; p-value 0.0001) Conclusion: Vitamin D supplementation is a safe and cost-friendly approach to reducing asthma exacerbations. It may also help to improve the condition in severe asthmatics with low vitamin D levels.

Changes in Levels of Serum Insulin, C-Peptide and Glucose after Electroacupuncture and Diet Therapy in Obese Women

2006 ◽  
Vol 34 (03) ◽  
pp. 367-376 ◽  
Author(s):  
Mehmet Tuğrul Cabıoğlu ◽  
Neyhan Ergene
Keyword(s):  
Weight Loss ◽  
Serum Insulin ◽  
Diet Therapy ◽  
Serum Glucose ◽  
The Body ◽  
Obese Women ◽  
Diet Restriction ◽  
C Peptide ◽  
Glucose Levels ◽  
Restriction Group

Our purpose was to investigate the effects of electroacupuncture (EA) therapy on body weight and on levels of serum insulin, c-peptide and glucose in obese women. 52 healthy women were included in this study and were allocated into three groups: 1) Placebo EA group ( n = 15; mean age = 41.8 ± 4.6 and mean body mass index { BMI } = 33.2 ± 3.5); 2) EA group ( n = 20; mean age = 42.1 ± 4.4 and BMI = 35.9 ± 3.6) and 3) Diet restriction group ( n = 20; mean age = 42.9 ± 4.3 and BMI = 34.7 ± 2.7). EA was applied to the ear points Hunger and Shen Men on alternating days and to the body points LI 4, LI 11, St 36 and St 44 once a day for 30 minutes over 20 days. Diet restriction that entailed a 1450 kilocalorie (kcal) diet program was applied to the three groups for 20 days. An increase in weight loss was observed when weight loss in the EA group (p < 0.000) was compared to that in the diet restricted and placebo EA groups using the Tukey HSD test. There were increases in the serum insulin (p < 0.001) and c-peptide levels (p < 0.000) in the women treated with EA compared to those in the women treated with the placebo EA and diet restriction groups. A decrease was observed in the glucose levels (p < 0.01)in both the EA and diet restriction groups compared to those in the placebo EA group. Our results suggest that EA therapy is an effective method in treating obesity. EA therapy also helps serum glucose levels to decrease through the increase of serum insulin and c-peptide levels.

scholarly journals GIVING RED RICE (ORIZA NIVARA) TO CHANGE GLUCOSE LEVELS IN DIABETES MELLITUS PATIENTS IN KENDARI CITY

2021 ◽  
Vol 3 (1) ◽  
pp. 38-44
Author(s):  
La Ode Ardiansyah ◽  
Nawawi Nawawi
Keyword(s):  
Diabetes Mellitus ◽  
Blood Glucose ◽  
Brown Rice ◽  
Secondary Data ◽  
The Body ◽  
P Value ◽  
Red Rice ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Quasi Experimental

Background:Diabetes mellitus (DM) is a phenomenon which the body  cannot  produce insulin supply which is indicated by increasing blood glucose levels. Red Rice (Oriza nivara) contains flavonoid compounds which have antidiabetic abilities. It can  reduce blood glucose by increasing insulin secretion and preventing insulin resistance. This study aims to determine the effect of giving brown rice (Oriza nivara) to change   blood glucose levels in people with diabetes mellitus in Kendari City. Methods: This research method was carried out with a quasi-experimental design with pre-post test design for 1 week with primary and secondary data collection techniques. The respondents  were  determined by proportional random sampling. Respondents in this study were 33 people with DM. Result:The results of the study on checking blood glucose levels before and after giving brown rice (oriza nivara) within 1 week obtained P value = 0.000 <  alpha 0.05. Conclusion: there is a  significant  effect of giving brown rice (oriza nivara) on changes in blood glucose level in diabetes mellitus people  in Kendari City.

scholarly journals Neurokinin 3 receptor antagonism ameliorates key metabolic features in a hyperandrogenic PCOS mouse model

Endocrinology ◽  
2021 ◽  
Author(s):  
Irene E Sucquart ◽  
Ruchi Nagarkar ◽  
Melissa C Edwards ◽  
Valentina Rodriguez Paris ◽  
Ali Aflatounian ◽  
...  
Keyword(s):  
Body Weight ◽  
Mouse Model ◽  
Polycystic Ovary ◽  
Serum Triglyceride ◽  
Total Body Weight ◽  
Neurokinin B ◽  
Glucose Levels ◽  
Neurokinin 3 Receptor ◽  
Total Body ◽  
Novel Therapeutic Strategies

Abstract Polycystic ovary syndrome (PCOS) is a prevalent endocrine condition characterised by a range of endocrine, reproductive and metabolic abnormalities. At present, management of women with PCOS is suboptimal as treatment is only symptomatic. Clinical and experimental advances in our understanding of PCOS etiology support a pivotal role for androgen neuroendocrine actions in PCOS pathogenesis. Hyperandrogenism is a key PCOS trait and androgen actions play a role in regulating the kisspeptin-/neurokinin B-/dynorphin (KNDy) system. This study aimed to investigate if targeted antagonism of neurokinin B signalling through the neurokinin 3 receptor (NK3R) would reverse PCOS traits in a dihydrotestosterone (DHT)-induced mouse model of PCOS. After 3 months, DHT exposure induced key reproductive PCOS traits of cycle irregularity and ovulatory dysfunction, and PCOS-like metabolic traits including increased body weight; white and brown fat pad weights; fasting serum triglyceride and glucose levels and blood glucose iAUC. Treatment with a NK3R antagonist (MLE4901) did not impact the observed reproductive defects. In contrast, following NK3R antagonist treatment, PCOS-like females displayed decreased total body weight, adiposity and adipocyte hypertrophy, but increased respiratory exchange ratio, suggesting NK3R antagonism altered the metabolic status of the PCOS-like females. NK3R antagonism did not improve circulating serum triglyceride or fasted glucose levels. Collectively, these findings demonstrate that NK3R antagonism may be beneficial in the treatment of adverse metabolic features associated with PCOS and support neuroendocrine targeting in the development of novel therapeutic strategies for PCOS.

Ion and Water Balance in the Ixodid Tick Dermacentor Andersoni

1973 ◽  
Vol 58 (2) ◽  
pp. 523-536
Author(s):  
W. R. KAUFMAN ◽  
J. E. PHILLIPS
Keyword(s):  
Body Weight ◽  
Extracellular Fluid ◽  
Total Body Weight ◽  
Ixodid Tick ◽  
The Body ◽  
Dermacentor Andersoni ◽  
Adult Feeding ◽  
Feeding Cycle ◽  
Total Body ◽  
Sodium And Potassium

1. Of the total meal imbibed by female Dermacentor andersoni during the normal adult feeding cycle, about 80% is excreted. Of the total water excreted by the tick, 75% is removed by salivation, less than 3% is evaporated from the integument and spiracles, and the remainder is lost via the anus. 2. Of the total excreted sodium and potassium, 4 and 82% respectively are lost via the anus. The remainder in each case is presumed excreted via the salivary glands. 3. The ionic and osmotic concentrations of the haemolymph and saliva stabilize at constant values by the third or fourth day of feeding. The volume of extracellular fluid is constantly maintained at 23% of the body weight, even though the total body weight increases 75 times over the unfed weight, and the volume of excreted fluid passing through the haemolymph is about ten times the haemolymph volume at repletion.

Effects of long-term treatment with growth hormone-releasing peptide-2 in the GHRH knockout mouse

2005 ◽  
Vol 289 (5) ◽  
pp. E762-E767 ◽  
Author(s):  
Maria Alba ◽  
Danilo Fintini ◽  
Cyril Y. Bowers ◽  
A. F. Parlow ◽  
Roberto Salvatori
Keyword(s):  
Growth Hormone ◽  
Cell Mass ◽  
Total Body Weight ◽  
Term Treatment ◽  
The Body ◽  
Ghrelin Receptor ◽  
Gh Secretion ◽  
Long Term Treatment ◽  
Total Body

Growth hormone (GH) secretagogues (GHS) stimulate GH secretion in vivo in humans and in animals. They act on the ghrelin receptor, expressed in both the hypothalamus and the pituitary. It is unknown whether GHSs act predominantly by increasing the release of hypothalamic GH-releasing hormone (GHRH) or by acting directly on the somatotroph cells. We studied whether a potent GHS could stimulate growth in the absence of endogenous GHRH. To this end, we used GHRH knockout (GHRH-KO) mice. These animals have proportionate dwarfism due to severe GH deficiency (GHD) and pituitary hypoplasia due to reduced somatotroph cell mass. We treated male GHRH-KO mice for 6 wk (from week 1 to week 7 of age) with GH-releasing peptide-2 (GHRP-2, 10 μg sc twice a day). Chronic treatment with GHRP-2 failed to stimulate somatotroph cell proliferation and GH secretion and to promote longitudinal growth. GHRP-2-treated mice showed an increase in total body weight compared with placebo-treated animals, due to worsening of the body composition alterations typical of GHD animals. These data demonstrate that GHRP-2 failed to reverse the severe GHD caused by lack of GHRH.

La fraye d'une population d'éperlans géants, Osmerus eperlanus mordax, au lac Heney, Comté de Gatineau, Québec

1968 ◽  
Vol 25 (9) ◽  
pp. 1813-1830 ◽  
Author(s):  
Roméo-O. Legault ◽  
Claude Delisle
Keyword(s):  
Body Weight ◽  
Total Body Weight ◽  
The Body ◽  
Testis Weight ◽  
Spawning Period ◽  
Weight One ◽  
Total Body ◽  
Set Up ◽  
The Right ◽  
Two Populations

Two sympatric smelt populations inhabit Lake Heney, Gatineau County, Quebec. This study deals only with the population which we call "giant" but a brief discussion on "small smelt — large smelt" theory is included. The data were obtained from 1556 specimens collected with eight gillnets set up under the ice at one locality on Lake Heney, in February, March, and April 1967. The data permitted the determination of the time and site of spawning in the giant population. The time and site of spawning in the "dwarf" population was already known, and we found a marked difference in the spawning behavior and time of spawning of the two populations. The two populations are furthermore reproductively isolated. The sex ratio during the spawning period was closely followed and found to be similar to that of all other freshwater or marine smelts. A DeGiusti dredge, dragged along the bottom below the position of the gillnets immediately after the melting of the ice, permitted the collection of embryonic smelt eggs from a depth of 30–40 ft.The maturity index, relative fecundity, and intergonadal ratio were especially studied. Ovary weight at maturity represents in average one-quarter the total body weight, and testis weight one-fortieth the body weight. A 213-mm female lays an average of 42,460 eggs. The right ovary is 4.5 times smaller than the left one, and the right testis is on the average 3.8 times smaller than the left one.There is a direct relationship between total fecundity and length of mature females. This relation is expressed by the curve log E = 4.54 log L + k.

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